{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T14:19:08Z","timestamp":1780323548300,"version":"3.54.1"},"reference-count":10,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jogc.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Obstetrics and Gynaecology Canada"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.jogc.2025.102773","type":"journal-article","created":{"date-parts":[[2025,1,28]],"date-time":"2025-01-28T19:07:18Z","timestamp":1738091238000},"page":"102773","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Xylazine: An Emerging Threat in Obstetrics"],"prefix":"10.1016","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-9406-015X","authenticated-orcid":false,"given":"Suzanne","family":"Turner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jocelyn","family":"Cook","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Graves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jogc.2025.102773_bib1","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1186\/s12954-021-00546-9","article-title":"Xylazine detected in unregulated opioids and drug administration equipment in Toronto, Canada: clinical and social implications","volume":"18","author":"Bowles","year":"2021","journal-title":"Harm Reduct J"},{"key":"10.1016\/j.jogc.2025.102773_bib2","doi-asserted-by":"crossref","first-page":"277","DOI":"10.17161\/kjm.vol16.20624","article-title":"Xylazine use in pregnancy: the effects of the fentanyl adulterant xylazine on pregnant patients and the developing fetus","volume":"16","author":"Noonan","year":"2023","journal-title":"Kans J Med"},{"key":"10.1016\/j.jogc.2025.102773_bib3","article-title":"Xylazine-induced skin ulcers in a person who injects drugs in Philadelphia, Pennsylvania, USA","volume":"14","author":"Malayala","year":"2022","journal-title":"Cureus"},{"key":"10.1016\/j.jogc.2025.102773_bib4","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.brainres.2013.02.030","article-title":"Xylazine induced central antinociception mediated by endogenous opioids and \u03bc-opioid receptor, but not \u03b4-or \u03ba-opioid receptors","volume":"1506","author":"Romero","year":"2013","journal-title":"Brain Res"},{"key":"10.1016\/j.jogc.2025.102773_bib5","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/0735-6757(86)90070-7","article-title":"Human overdose with the veterinary tranquilizer xylazine","volume":"4","author":"Spoerke","year":"1986","journal-title":"Am J Emerg Med"},{"key":"10.1016\/j.jogc.2025.102773_bib6","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1080\/15563650.2016.1277234","article-title":"Adult clonidine overdose: prolonged bradycardia and central nervous system depression, but not severe toxicity","volume":"55","author":"Isbister","year":"2017","journal-title":"Clin Toxicol"},{"key":"10.1016\/j.jogc.2025.102773_bib7","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.2460\/ajvr.2002.63.1695","article-title":"Cardiopulmonary effects of xylazine and acepromazine in pregnant cows in late gestation","volume":"63","author":"Hodgson","year":"2002","journal-title":"Am J Vet Res"},{"key":"10.1016\/j.jogc.2025.102773_bib8","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1159\/000292600","article-title":"Alpha-adrenergic receptors in human myometrium: changes during pregnancy","volume":"36","author":"Dahle","year":"1993","journal-title":"Gynecol Obstet Investig"},{"key":"10.1016\/j.jogc.2025.102773_bib9","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.rvsc.2016.07.002","article-title":"Lidocaine decreases the xylazine-evoked contractility in pregnant cows","volume":"107","author":"Piccinno","year":"2016","journal-title":"Res Vet Sci"},{"key":"10.1016\/j.jogc.2025.102773_bib10","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1016\/j.theriogenology.2014.01.031","article-title":"Effect of xylazine, isoxsuprine, and lidocaine on Doppler sonographic uterine and umbilical blood flow measurements in cows during the last month of pregnancy","volume":"81","author":"Waldvogel","year":"2014","journal-title":"Theriogenology"}],"container-title":["Journal of Obstetrics and Gynaecology Canada"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1701216325000131?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1701216325000131?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T16:12:05Z","timestamp":1761840725000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1701216325000131"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":10,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["S1701216325000131"],"URL":"https:\/\/doi.org\/10.1016\/j.jogc.2025.102773","relation":{},"ISSN":["1701-2163"],"issn-type":[{"value":"1701-2163","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Xylazine: An Emerging Threat in Obstetrics","name":"articletitle","label":"Article Title"},{"value":"Journal of Obstetrics and Gynaecology Canada","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jogc.2025.102773","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Society of Obstetricians and Gynaecologists of Canada\/La Soci\u00e9t\u00e9 des obst\u00e9triciens et gyn\u00e9cologues du Canada. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}],"article-number":"102773"}}