{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T05:20:14Z","timestamp":1772428814308,"version":"3.50.1"},"reference-count":40,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Gynecology Obstetrics and Human Reproduction"],"published-print":{"date-parts":[[2017,3]]},"DOI":"10.1016\/j.jogoh.2016.10.007","type":"journal-article","created":{"date-parts":[[2017,2,3]],"date-time":"2017-02-03T20:26:20Z","timestamp":1486153580000},"page":"211-218","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Contraception des femmes en p\u00e9rim\u00e9nopause\u00a0: place des spermicides"],"prefix":"10.1016","volume":"46","author":[{"given":"D.","family":"Serfaty","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jogoh.2016.10.007_bib0205","doi-asserted-by":"crossref","first-page":"ITC1","DOI":"10.7326\/AITC201502030","volume":"162","author":"McNamara","year":"2015","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0210","series-title":"Tables on the French economy\u00a0\u2013\u00a0birth rate fecundity","author":"INSEE","year":"2013"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0215","series-title":"Tables on the French economy\u00a0\u2013\u00a0birth rate fecundity","author":"INSEE","year":"2015"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0220","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1503\/cmaj.121280","article-title":"Contraception in women over 40 years of age","volume":"185","author":"Allen","year":"2013","journal-title":"CMAJ"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0225","series-title":"La contraception","author":"Serfaty","year":"2016"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0230","doi-asserted-by":"crossref","first-page":"365","DOI":"10.3917\/popu.1403.0365","article-title":"Le nombre d\u2019IVG est stable, mais moins de femmes y ont recours","volume":"69","author":"Mazuy","year":"2014","journal-title":"Population-F"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0235","series-title":"Strat\u00e9gies de choix des m\u00e9thodes contraceptives chez la femme. Recommandations pour la pratique clinique. Argumentaire","author":"Agence nationale d\u2019accr\u00e9ditation et d\u2019\u00e9valuation en sant\u00e9","year":"2004"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0240","article-title":"La crise de la pilule en France\u00a0: vers un nouveau mod\u00e8le contraceptif\u00a0?","volume":"511","author":"Bajos","year":"2014","journal-title":"Popul Soc"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0245","series-title":"Fiches m\u00e9mo contraception chez l\u2019homme et chez la femme. Document de travail","author":"Haute Autorit\u00e9 de sant\u00e9","year":"2013"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0250","series-title":"Contraception for women aged over 40 years. Clinical guidance","author":"Faculty of Sexual and Reproductive Healthcare","year":"2010"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0255","series-title":"Long-acting reversible contraception the effective and appropriate use of long-acting reversible contraception","author":"National Collaborating Centre for Women's and Children's Health","year":"2005"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0260","series-title":"Reproductive health. Medical eligibility criteria for contraceptive use","author":"World Health Organization","year":"2015"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0265","author":"Faculty of Family Planning and Reproductive Health Care"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0270","doi-asserted-by":"crossref","first-page":"d6423","DOI":"10.1136\/bmj.d6423","article-title":"Risk of venous thromboembolism from use of oral contraceptives containing different progestogens and oestrogen doses: Danish cohort study, 2001-9","volume":"343","author":"Lidegaard","year":"2011","journal-title":"BMJ"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0275","series-title":"Clinical guidance. Barrier methods for contraception and STI prevention","author":"Faculty of Sexual and Reproductive Healthcare","year":"2012"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0280","first-page":"CD005218","article-title":"Spermicide used alone for contraception","volume":"12","author":"Grimes","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0285","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1080\/13625180802263515","article-title":"Update on nonoxynol-9 as vaginal spermicide","volume":"13","author":"Iyer","year":"2008","journal-title":"Eur J Contracept Reprod Health Care"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0290","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/S1297-9589(01)00213-2","article-title":"La contraception locale spermicide","volume":"29","author":"Marmor","year":"2001","journal-title":"Gynecol Obstet Fertil"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0295","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/0010-7824(86)90088-0","article-title":"Use effectiveness of a spermicidal suppository containing benzalkonium chloride","volume":"34","author":"Mendez","year":"1986","journal-title":"Contraception"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0300","first-page":"209","article-title":"Diagramme enzymatique du spermicide humain. Application \u00e0 l\u2019\u00e9tude in vitro du chlorure de benzalkonium","volume":"7","author":"Menezo","year":"1979","journal-title":"Contracept Fertil Sex"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0305","first-page":"633","article-title":"Contraception par ovules au chlorure de benzalkonium","volume":"31","author":"Levrier","year":"1980","journal-title":"Gynecologie"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0310","first-page":"11","article-title":"\u00c9tude pr\u00e9liminaire au microscope \u00e9lectronique \u00e0 balayage des effets d\u2019un spermicide tensio-actif cationique sur la membrane plasmique des spermatozo\u00efdes","volume":"14","author":"Chr\u00e9tien","year":"1986","journal-title":"Contracept Fertil Sex"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0315","first-page":"767","article-title":"Les tampons au chlorure de benzalkonium. Tol\u00e9rance locale et effets sur la glaire cervicale","volume":"12","author":"Erny","year":"1983","journal-title":"J Gyn Obst Biol Repr"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0320","first-page":"551","article-title":"Contraception vaginale et tensio-actifs","volume":"9","author":"Langlois","year":"1981","journal-title":"Contracept Fertil Sex"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0325","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.contraception.2011.01.021","article-title":"Contraceptive failure in the United States","volume":"83","author":"Trussell","year":"2011","journal-title":"Contraception"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0330","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1097\/01.AOG.0000113620.18395.0b","article-title":"Contraceptive effectiveness and safety of five nonoxynol-9 spermicides: a randomized trial","volume":"103","author":"Raymond","year":"2004","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0335","doi-asserted-by":"crossref","first-page":"56","DOI":"10.2307\/2991640","article-title":"Contraceptive failure rates: new estimates from the 1995 National Survey of Family Growth","volume":"31","author":"Fu","year":"1999","journal-title":"Fam Plann Perspect"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0340","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/j.contraception.2012.09.012","article-title":"Effectiveness of an optimized benzalkonium chloride gel as vaginal contraceptive: a randomized controlled trial among Chinese women","volume":"87","author":"Li","year":"2013","journal-title":"Contraception"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0345","doi-asserted-by":"crossref","first-page":"89","DOI":"10.3109\/13625180903462326","article-title":"State-of-the-art of non-hormonal methods of contraception: I. Chemical barrier contraceptives","volume":"15","author":"Batar","year":"2010","journal-title":"Eur J Contracept Reprod Health Care"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0350","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/0378-4274(82)90214-4","article-title":"Transvaginal absorption and disposition of nonoxynol-9 in gravid rats","volume":"13","author":"Buttar","year":"1982","journal-title":"Toxicol Lett"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0355","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/S0010-7824(80)80010-2","article-title":"Studies on nonoxynol-9. II. Intravaginal absorption, distribution, metabolism and excretion in rats and rabbits","volume":"22","author":"Chvapil","year":"1980","journal-title":"Contraception"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0360","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.jgyn.2014.07.001","article-title":"[Contraception in breastfeeding women: place for spermicides]","volume":"44","author":"Serfaty","year":"2015","journal-title":"J Gynecol Obstet Biol Reprod (Paris)"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0365","doi-asserted-by":"crossref","first-page":"589","DOI":"10.3109\/10915818909010524","article-title":"Final report on the safety assessment of benzalkonium chloride","volume":"8","author":"Liebert","year":"1989","journal-title":"J Am Coll Toxicol"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0370","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.ejpb.2005.01.012","article-title":"The evaluation of the local tolerance of vaginal formulations containing dapivirine using the Slug Mucosal Irritation test and the rabbit vaginal irritation test","volume":"60","author":"Dhondt","year":"2005","journal-title":"Eur J Pharm Biopharm"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0375","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1095\/biolreprod.104.029603","article-title":"Interleukin (IL)-1, IL-6, and IL-8 predict mucosal toxicity of vaginal microbicidal contraceptives","volume":"71","author":"Fichorova","year":"2004","journal-title":"Biol Reprod"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0380","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.tox.2010.10.001","article-title":"Development of an in vitro alternative assay method for vaginal irritation","volume":"279","author":"Ayehunie","year":"2011","journal-title":"Toxicology"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0385","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1080\/13625180008500373","article-title":"Local spermicidal contraception: a comparative study of the acceptability and safety of a new pharmaceutical formulation of benzalkonium chloride, the vaginal capsule, with a reference formulation, the pessary","volume":"5","author":"Aubeny","year":"2000","journal-title":"Eur J Contracept Reprod Health Care"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0390","doi-asserted-by":"crossref","first-page":"e19850","DOI":"10.1371\/journal.pone.0019850","article-title":"In vitro surfactant structure-toxicity relationships: implications for surfactant use in sexually transmitted infection prophylaxis and contraception","volume":"6","author":"Inacio","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0395","doi-asserted-by":"crossref","first-page":"3693","DOI":"10.2174\/0929867321666140826115929","article-title":"Spermicidal and microbicidal compounds: in search of an efficient multipurpose strategy","volume":"21","author":"Baptista","year":"2014","journal-title":"Curr Med Chem"},{"key":"10.1016\/j.jogoh.2016.10.007_bib0400","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1001\/jama.1992.03490040053025","article-title":"Efficacy of nonoxynol 9 contraceptive sponge use in preventing heterosexual acquisition of HIV in Nairobi prostitutes","volume":"268","author":"Kreiss","year":"1992","journal-title":"JAMA"}],"container-title":["Journal of Gynecology Obstetrics and Human Reproduction"],"original-title":[],"language":"fr","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S246878471730017X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S246878471730017X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,11,6]],"date-time":"2021-11-06T22:08:37Z","timestamp":1636236517000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S246878471730017X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3]]},"references-count":40,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["S246878471730017X"],"URL":"https:\/\/doi.org\/10.1016\/j.jogoh.2016.10.007","relation":{},"ISSN":["2468-7847"],"issn-type":[{"value":"2468-7847","type":"print"}],"subject":[],"published":{"date-parts":[[2017,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Contraception des femmes en p\u00e9rim\u00e9nopause\u00a0: place des spermicides","name":"articletitle","label":"Article Title"},{"value":"Journal of Gynecology Obstetrics and Human Reproduction","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jogoh.2016.10.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Published by Elsevier Masson SAS.","name":"copyright","label":"Copyright"}]}}