{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:59:24Z","timestamp":1786993164771,"version":"build-2736575974"},"reference-count":51,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Integrative Medicine"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.joim.2018.07.005","type":"journal-article","created":{"date-parts":[[2018,7,29]],"date-time":"2018-07-29T00:32:55Z","timestamp":1532824375000},"page":"350-357","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":64,"title":["Antimicrobial activity of Cannabis sativa, Thuja orientalis and Psidium guajava leaf extracts against methicillin-resistant Staphylococcus aureus"],"prefix":"10.1016","volume":"16","author":[{"given":"Shohini","family":"Chakraborty","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nashra","family":"Afaq","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neelam","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sukanta","family":"Majumdar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.joim.2018.07.005_b0005","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1111\/j.1469-0691.2006.01573.x","article-title":"The molecular evolution of methicillin resistant Staphylococcus aureus","volume":"13","author":"Deurenberg","year":"2007","journal-title":"Clin Microbiol Infect"},{"issue":"5219","key":"10.1016\/j.joim.2018.07.005_b0010","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1136\/bmj.1.5219.125","article-title":"\u201cCelbenin\u201d-resistant Staphylococci","volume":"1","author":"Rolinson","year":"1961","journal-title":"Br Med J"},{"issue":"10","key":"10.1016\/j.joim.2018.07.005_b0015","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0077477","article-title":"Prevalence of clonal complexes and virulence genes among commensal and invasive Staphylococcus aureus isolates in Sweden","volume":"8","author":"Rasmussen","year":"2013","journal-title":"PLoS One"},{"issue":"6","key":"10.1016\/j.joim.2018.07.005_b0020","doi-asserted-by":"crossref","first-page":"263","DOI":"10.4081\/pmc.2013.21","article-title":"Management of out breaks of nosocomial pathogens in neonatal intensive care unit","volume":"35","author":"Ghirardi","year":"2013","journal-title":"Pediatr Med Chir"},{"issue":"11","key":"10.1016\/j.joim.2018.07.005_b0025","doi-asserted-by":"crossref","first-page":"3638","DOI":"10.1128\/JCM.01375-13","article-title":"National surveillance of methicillin-resistant Staphylococcus aureus in China highlights a still-evolving epidemiology with 15 novel emerging multilocus sequence types","volume":"51","author":"Xiao","year":"2013","journal-title":"J Clin Microbiol"},{"issue":"10","key":"10.1016\/j.joim.2018.07.005_b0030","doi-asserted-by":"crossref","first-page":"3817","DOI":"10.1128\/AAC.00613-08","article-title":"Antimicrobial resistance of old and recent Staphylococcus aureus isolates from poultry: first detection of livestock-associated methicillin-resistant strain ST398","volume":"52","author":"Nemati","year":"2008","journal-title":"Antimicrob Agents Chemother"},{"issue":"2","key":"10.1016\/j.joim.2018.07.005_b0035","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.ijantimicag.2009.03.004","article-title":"Comparative evaluation of epidemiology and outcomes of methicillin-resistant Staphylococcus aureus (MRSA) USA300 infections causing community- and healthcare-associated infections","volume":"34","author":"Moore","year":"2009","journal-title":"Int J Antimicrob Agents"},{"issue":"4","key":"10.1016\/j.joim.2018.07.005_b0040","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.jhin.2009.07.004","article-title":"Community-associated methicillin-resistant Staphylococcus aureus as a cause of hospital-acquired infections","volume":"73","author":"Skov","year":"2009","journal-title":"J Hosp Infect"},{"issue":"2","key":"10.1016\/j.joim.2018.07.005_b0045","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1086\/524672","article-title":"Increase in a Dutch hospital of methicillin-resistant Staphylococcus aureus related to animal farming","volume":"46","author":"van Rijen","year":"2008","journal-title":"Clin Infect Dis"},{"issue":"2","key":"10.1016\/j.joim.2018.07.005_b0050","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1086\/502360","article-title":"Carriage of methicillin-resistant Staphylococcus aureus among hospital employees: prevalence, duration, and transmission to households","volume":"25","author":"Eveillard","year":"2004","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"4","key":"10.1016\/j.joim.2018.07.005_b0055","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1093\/jac\/dkh422","article-title":"A European survey of antimicrobial susceptibility among zoonotic and commensal bacteria isolated from food-producing animals","volume":"54","author":"Bywater","year":"2004","journal-title":"J Antimicrob Chemother"},{"issue":"1\u20132","key":"10.1016\/j.joim.2018.07.005_b0060","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.ijfoodmicro.2008.12.007","article-title":"Prevalence of methicillin-resistant Staphylococcus aureus in meat","volume":"134","author":"de Boer","year":"2009","journal-title":"Intl J Food Microbiol"},{"issue":"2","key":"10.1016\/j.joim.2018.07.005_b0065","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.ijfoodmicro.2007.04.006","article-title":"Methicillin-resistant Staphylococcus aureus (MRSA) in foods of animal origin product in Italy","volume":"117","author":"Normanno","year":"2007","journal-title":"Int J Food Microbiol"},{"issue":"7","key":"10.1016\/j.joim.2018.07.005_b0070","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1111\/1750-3841.13346","article-title":"Characterization of extended spectrum \u03b2-lactamase producing enterobacteria and methicillin-resistant Staphylococcus aureus isolated from raw pork and cooked pork products in south China","volume":"81","author":"Li","year":"2016","journal-title":"J Food Sci"},{"issue":"1","key":"10.1016\/j.joim.2018.07.005_b0075","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1111\/1750-3841.12723","article-title":"Methicillin-resistant Staphylococcus aureus in raw meats and prepared foods in public hospitals in Salvador, Bahia","volume":"80","author":"Costa","year":"2015","journal-title":"Brazil. J Food Sci"},{"issue":"3","key":"10.1016\/j.joim.2018.07.005_b0080","first-page":"134","article-title":"Synergistic effects of plant extracts and antibiotics on Staphylococcus aureus strains isolated from clinical specimens","volume":"3","author":"Adwan","year":"2008","journal-title":"Middle East J Sci Res"},{"issue":"9","key":"10.1016\/j.joim.2018.07.005_b0085","first-page":"52","article-title":"In vitro antibacterial potentials and synergistic effect of south-western Nigerian plant parts used in folklore remedy for Salmonella typhi infection","volume":"8","author":"Oluduro","year":"2010","journal-title":"Nat Sci"},{"issue":"11","key":"10.1016\/j.joim.2018.07.005_b0090","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1055\/s-0030-1270904","article-title":"Botanical drugs, synergy, and network pharmacology: forth and back to intelligent mixtures","volume":"77","author":"Gertsch","year":"2011","journal-title":"Planta Med"},{"key":"10.1016\/j.joim.2018.07.005_b0095","first-page":"49","article-title":"Study of the antimicrobial activity and synergistic effect of some plant extracts and essential oils","volume":"18","author":"Gy\u00f6rgy","year":"2010","journal-title":"Rev Rom\u00e2n\u0103 Med Lab"},{"issue":"1","key":"10.1016\/j.joim.2018.07.005_b0100","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.apjtb.2015.09.024","article-title":"Evaluation of antibacterial activity and synergistic effect between antibiotic and the essential oils of some medicinal plants","volume":"6","author":"Moussaoui","year":"2016","journal-title":"Asian Pac J Trop Biomed"},{"key":"10.1016\/j.joim.2018.07.005_b0105","first-page":"520","article-title":"Combination therapy: synergism between natural plant extracts and antibiotics against infectious diseases","author":"Chanda","year":"2011","journal-title":"Sci Microb Pathog"},{"key":"10.1016\/j.joim.2018.07.005_b0110","series-title":"Fighting multidrug resistance with herbal extracts, essential oils and their components","first-page":"165","article-title":"Medicinal plants as alternative sources of therapeutics against multidrug-resistant pathogenic microorganisms based on their antimicrobial potential and synergistic properties","author":"Rakholiya","year":"2013"},{"key":"10.1016\/j.joim.2018.07.005_b0115","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2013\/760969","article-title":"In vitro antibacterial and antibiotic resistance modifying effect of bioactive plant extracts on methicillin-resistant Staphylococcus epidermidis","volume":"2013","author":"Chovanov\u00e1","year":"2013","journal-title":"Int J Microb"},{"issue":"3","key":"10.1016\/j.joim.2018.07.005_b0120","first-page":"741","article-title":"Synergism of antibiotics and plant extracts in antibacterial activity against methicillin resistant Staphylococcus aureus (MRSA)","volume":"4","author":"Blesson","year":"2014","journal-title":"World J Pharm Pharm Sci"},{"issue":"3","key":"10.1016\/j.joim.2018.07.005_b0125","first-page":"409","article-title":"A classification of micrococci and staphylococci based on physiological and biochemical tests","volume":"30","author":"Baird-Parker","year":"1963","journal-title":"Microbiology"},{"issue":"1","key":"10.1016\/j.joim.2018.07.005_b0130","first-page":"13","article-title":"Isolation and identification of Staphylococcus species from raw bovine milk in Debre Zeit, Ethiopia","volume":"4","author":"Addis","year":"2011","journal-title":"Vet Res"},{"issue":"9","key":"10.1016\/j.joim.2018.07.005_b0135","first-page":"106","article-title":"Tannin extract of guava leaves (Psidium guajava L) variation with concentration organic solvents","volume":"2","author":"Mailoa","year":"2013","journal-title":"Int J Sci Technol Res"},{"key":"10.1016\/j.joim.2018.07.005_b0140","unstructured":"Helrich K. Association of official analytical chemists (AOAC). In: Helrich K. Official method of analysis, 15th ed., Arlington, Virginia; 1990."},{"issue":"2","key":"10.1016\/j.joim.2018.07.005_b0145","first-page":"53","article-title":"Review on nutritional medicinal and pharmacological properties of Psidium guajava","volume":"124","author":"Joseph","year":"2011","journal-title":"Int J Pharma Bio Sci"},{"key":"10.1016\/j.joim.2018.07.005_b0150","first-page":"157","article-title":"Antimicrobial activities of various medicinal and commercial plant extracts","volume":"27","author":"Ate\u015f","year":"2003","journal-title":"Turk J Biol"},{"issue":"25","key":"10.1016\/j.joim.2018.07.005_b0155","first-page":"1886","article-title":"Antibacterial, antioxidant and phytochemical investigation of Thuja orientalis leaves","volume":"7","author":"Jasuja","year":"2013","journal-title":"J Med Plants Res"},{"issue":"4","key":"10.1016\/j.joim.2018.07.005_b0160","first-page":"493","article-title":"Antibiotic by standardized single disk method","volume":"45","author":"Bauer","year":"1996","journal-title":"Am J Clin Path"},{"key":"10.1016\/j.joim.2018.07.005_b0165","unstructured":"NCCLS Reference method for broth dilution antifungal susceptibility testing of yeasts; approved standard\u2014second edition 2002 Wayne, Pennsylvania: NCCLS."},{"key":"10.1016\/j.joim.2018.07.005_b0170","series-title":"Reference method for broth dilution antifungal susceptibility testing filamentous fungi, approved standard\u2014second edition","author":"Clinical and Laboratory Standards Institute","year":"2008"},{"issue":"3","key":"10.1016\/j.joim.2018.07.005_b0175","first-page":"1194","article-title":"Preliminary phytochemical screening and HPTLC finger print profile of Tragia plukenetii","volume":"8","author":"Kalaivanan","year":"2016","journal-title":"Int J Pharm Sci Res"},{"issue":"2","key":"10.1016\/j.joim.2018.07.005_b0180","doi-asserted-by":"crossref","first-page":"162","DOI":"10.4103\/0973-8258.54912","article-title":"Phytochemical analysis and antibacterial activity of Vitex agnus-castus","volume":"3","author":"Arokiyaraj","year":"2009","journal-title":"Int J Green Pharm"},{"issue":"2","key":"10.1016\/j.joim.2018.07.005_b0185","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.jep.2007.09.031","article-title":"Evaluation of antimicrobial, antioxidant and wound healing potentials of Holoptelea integrifolia","volume":"115","author":"Reddy","year":"2008","journal-title":"J Ethnopharmacol"},{"issue":"3","key":"10.1016\/j.joim.2018.07.005_b0190","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1111\/j.1469-0691.2011.03570.x","article-title":"Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance","volume":"18","author":"Magiorakos","year":"2012","journal-title":"Clin Microbiol Infect"},{"issue":"Suppl. 1","key":"10.1016\/j.joim.2018.07.005_b0195","article-title":"Infections caused by Gram-positive bacteria: a review of the global challenge","volume":"59","author":"Woodford","year":"2009","journal-title":"J Infect"},{"issue":"1","key":"10.1016\/j.joim.2018.07.005_b0200","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.jgeb.2012.01.004","article-title":"Identification of Staphylococcus aureus and Escherichia coli isolated from Egyptian food by conventional and molecular methods","volume":"10","author":"El-Hadedy","year":"2012","journal-title":"J Genetic Eng Biotech"},{"issue":"6","key":"10.1016\/j.joim.2018.07.005_b0205","first-page":"974","article-title":"Prevalence of methicillin, vancomycin and multidrug resistance among Staphylococcus aureus","volume":"6","author":"Dhanalakshmi","year":"2012","journal-title":"J Clin Diagn Res"},{"key":"10.1016\/j.joim.2018.07.005_b0210","series-title":"Glossary of Indian medicinal plants","first-page":"7","author":"Chopra","year":"1992"},{"issue":"1","key":"10.1016\/j.joim.2018.07.005_b0215","first-page":"1","article-title":"Preliminary phytochemical analysis of the extracts of Psidium leaves","volume":"1","author":"Arya","year":"2012","journal-title":"J Pharmacog Phytochem"},{"issue":"6","key":"10.1016\/j.joim.2018.07.005_b0220","first-page":"375","article-title":"Antimicrobial activities of leaf extracts of guava (Psidium guajava L.) on two Gram-negative and Gram-positive bacteria","volume":"2","author":"Biswas","year":"2016","journal-title":"Int J Microbiol"},{"issue":"5","key":"10.1016\/j.joim.2018.07.005_b0225","first-page":"243","article-title":"Antibacterial and phytochemical investigation of Thuja orientalis (L.) leaves essential oil from","volume":"7","author":"Khubeiz","year":"2016","journal-title":"Syria. Int J Current Pharm Rev Res"},{"issue":"25","key":"10.1016\/j.joim.2018.07.005_b0230","first-page":"1886","article-title":"Antibacterial, antioxidant and phytochemical investigation of Thuja orientalis leaves","volume":"7","author":"Jasuja","year":"2013","journal-title":"J Med Plants Res"},{"issue":"3","key":"10.1016\/j.joim.2018.07.005_b0235","first-page":"604","article-title":"Phytochemical evaluation and HPTLC finger print profile of Cassia fistula","volume":"3","author":"Seasotiya","year":"2014","journal-title":"Int J Adv Pharm Biol Chem"},{"key":"10.1016\/j.joim.2018.07.005_b0240","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.fm.2014.08.002","article-title":"Antimicrobial activity of gallic acid against thermophilic Campylobacter is strain specific and associated with a loss of calcium ions","volume":"46","author":"Sarjit","year":"2015","journal-title":"Food Microbiol"},{"issue":"5","key":"10.1016\/j.joim.2018.07.005_b0245","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.ijantimicag.2005.09.002","article-title":"Antimicrobial activity of flavonoids","volume":"26","author":"Cushnie","year":"2005","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.joim.2018.07.005_b0250","series-title":"Food phytochemicals for cancer prevention II","first-page":"34","author":"Hara","year":"1994"},{"issue":"6","key":"10.1016\/j.joim.2018.07.005_b0255","first-page":"74","article-title":"Antimicrobial activity of the extract of Vernonia ambigua (aerial part)","volume":"2","author":"Kunle","year":"2010","journal-title":"Researcher"}],"container-title":["Journal of Integrative Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2095496418300815?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2095496418300815?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,8,30]],"date-time":"2018-08-30T19:17:01Z","timestamp":1535656621000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2095496418300815"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":51,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["S2095496418300815"],"URL":"https:\/\/doi.org\/10.1016\/j.joim.2018.07.005","relation":{},"ISSN":["2095-4964"],"issn-type":[{"value":"2095-4964","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Antimicrobial activity of Cannabis sativa, Thuja orientalis and Psidium guajava leaf extracts against methicillin-resistant Staphylococcus aureus","name":"articletitle","label":"Article Title"},{"value":"Journal of Integrative Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joim.2018.07.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Shanghai Changhai Hospital. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}