{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T17:31:46Z","timestamp":1762018306848,"version":"build-2065373602"},"reference-count":31,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Foundation of Key Discipline Construction of Zhejiang Province for Traditional Chinese Medicine","award":["2017-XK-A36"],"award-info":[{"award-number":["2017-XK-A36"]}]},{"name":"Foundation of Key Research Project of Zhejiang Province for Traditional Chinese Medicine","award":["2019ZZ014"],"award-info":[{"award-number":["2019ZZ014"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Integrative Medicine"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1016\/j.joim.2020.07.006","type":"journal-article","created":{"date-parts":[[2020,7,30]],"date-time":"2020-07-30T02:49:45Z","timestamp":1596077385000},"page":"434-440","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Clinical characteristics and outcomes of patients with hepatic veno-occlusive disease induced by Gynura segetum: A retrospective study"],"prefix":"10.1016","volume":"18","author":[{"given":"Meng-xiao","family":"Feng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan-qiang","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"5069","key":"10.1016\/j.joim.2020.07.006_b0005","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1016\/S0140-6736(01)00020-4","article-title":"Senecio disease, or cirrhosis of the liver due to Senecio poisoning","volume":"196","author":"Willmot","year":"1920","journal-title":"Lancet"},{"issue":"3","key":"10.1016\/j.joim.2020.07.006_b0010","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1046\/j.1365-2141.1999.01680.x","article-title":"The pathology, diagnosis, and treatment of hepatic veno-occlusive disease: current status and novel approaches","volume":"107","author":"Richardson","year":"1999","journal-title":"Br J Haematol"},{"issue":"4","key":"10.1016\/j.joim.2020.07.006_b0015","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1055\/s-2007-991515","article-title":"Hepatic microvasculature in liver injury","volume":"27","author":"DeLeve","year":"2007","journal-title":"Semin Liver Dis"},{"issue":"3","key":"10.1016\/j.joim.2020.07.006_b0020","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1188\/08.ONF.385-397","article-title":"Hepatic sinusoidal obstruction syndrome in patients undergoing hematopoietic stem cell transplant","volume":"35","author":"Eisenberg","year":"2008","journal-title":"Oncol Nurs Forum"},{"issue":"3","key":"10.1016\/j.joim.2020.07.006_b0025","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1038\/bmt.2015.283","article-title":"Sinusoidal obstruction syndrome after allogeneic hematopoietic stem cell transplantation: incidence, risk factors and outcomes","volume":"51","author":"Yakushijin","year":"2016","journal-title":"Bone Marrow Transplant"},{"issue":"1","key":"10.1016\/j.joim.2020.07.006_b0030","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1002\/hep.1840040121","article-title":"Venoocclusive disease of the liver after bone marrow transplantation: diagnosis, incidence, and predisposing factors","volume":"4","author":"McDonald","year":"1984","journal-title":"Hepatology"},{"issue":"6","key":"10.1016\/j.joim.2020.07.006_b0035","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1097\/00007890-198712000-00011","article-title":"Venoocclusive disease of the liver following bone marrow transplantation","volume":"44","author":"Jones","year":"1987","journal-title":"Transplantation"},{"issue":"5","key":"10.1016\/j.joim.2020.07.006_b0040","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1002\/hep.1840140511","article-title":"Azathioprine hepatotoxicity after liver transplantation","volume":"14","author":"Sterneck","year":"1991","journal-title":"Hepatology"},{"issue":"3","key":"10.1016\/j.joim.2020.07.006_b0045","first-page":"256","article-title":"Role of endothelial cell injury in the spectrum of azathioprine-induced liver disease after renal transplant: light microscopy and ultrastructural observations","volume":"83","author":"Haboubi","year":"1988","journal-title":"Am J Gastroenterol"},{"issue":"2","key":"10.1016\/j.joim.2020.07.006_b0050","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0268-960X(03)00002-X","article-title":"Veno-occlusive disease: cytokines, genetics, and haemostasis","volume":"17","author":"Coppell","year":"2003","journal-title":"Blood Rev"},{"issue":"3","key":"10.1016\/j.joim.2020.07.006_b0055","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1016\/S0022-3565(25)38620-9","article-title":"Dacarbazine toxicity in murine liver cells: a model of hepatic endothelial injury and glutathione defense","volume":"268","author":"Deleve","year":"1994","journal-title":"J Pharmacol Exp Ther"},{"issue":"15","key":"10.1016\/j.joim.2020.07.006_b0060","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000010415","article-title":"VEGF levels in plasma in relation to metabolic control, inflammation, and microvascular complications in type-2 diabetes: a cohort study","volume":"97","author":"Zhang","year":"2018","journal-title":"Medicine (Baltimore)"},{"issue":"4","key":"10.1016\/j.joim.2020.07.006_b0065","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1016\/j.jhep.2010.07.031","article-title":"Hepatic sinusoidal obstruction syndrome associated with consumption of Gynura segetum","volume":"54","author":"Lin","year":"2011","journal-title":"J Hepatol"},{"issue":"10","key":"10.1016\/j.joim.2020.07.006_b0070","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.3748\/wjg.v13.i10.1628","article-title":"Gynura root induces hepatic veno-occlusive disease: a case report and review of the literature","volume":"13","author":"Dai","year":"2007","journal-title":"World J Gastroenterol"},{"issue":"17","key":"10.1016\/j.joim.2020.07.006_b0075","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000010552","article-title":"Hepatic veno-occlusive disease related to Gynura segetum: a case report","volume":"97","author":"Sun","year":"2018","journal-title":"Medicine (Baltimore)"},{"issue":"12","key":"10.1016\/j.joim.2020.07.006_b0080","doi-asserted-by":"crossref","first-page":"3913","DOI":"10.1007\/s00204-017-2013-y","article-title":"First evidence of pyrrolizidine alkaloid N-oxide-induced hepatic sinusoidal obstruction syndrome in humans","volume":"91","author":"Yang","year":"2017","journal-title":"Arch Toxicol"},{"issue":"8","key":"10.1016\/j.joim.2020.07.006_b0085","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1111\/1753-0407.12480","article-title":"Association between the vascular endothelial growth factor single nucleotide polymorphisms and diabetic retinopathy risk: a meta-analysis","volume":"9","author":"Xie","year":"2017","journal-title":"J Diabetes"},{"issue":"6","key":"10.1016\/j.joim.2020.07.006_b0090","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1111\/j.1440-1746.2011.06661.x","article-title":"Effect of ligustrazine on mice model of hepatic veno-occlusive disease induced by Gynura segetum","volume":"26","author":"Chen","year":"2011","journal-title":"J Gastroenterol Hepatol"},{"issue":"1","key":"10.1016\/j.joim.2020.07.006_b0095","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1631\/jzus.B1200112","article-title":"Expression of MMP-9 in hepatic sinusoidal obstruction syndrome induced by Gynura segetum","volume":"14","author":"Yu","year":"2013","journal-title":"J Zhejiang Univ Sci B"},{"issue":"1","key":"10.1016\/j.joim.2020.07.006_b0100","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/j.1365-2036.2006.02742.x","article-title":"Review article: updates in the pathogenesis and therapy of hepatic sinusoidal obstruction syndrome","volume":"23","author":"Helmy","year":"2006","journal-title":"Aliment Pharmacol Ther"},{"issue":"Suppl 1","key":"10.1016\/j.joim.2020.07.006_b0105","doi-asserted-by":"crossref","first-page":"S25","DOI":"10.1016\/S0168-8278(12)60004-X","article-title":"Management of hepatic vascular diseases","volume":"56","author":"Plessier","year":"2012","journal-title":"J Hepatol"},{"issue":"5","key":"10.1016\/j.joim.2020.07.006_b0110","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1002\/hep.22772","article-title":"Vascular disorders of the liverVascular disorders of the liver","volume":"49","author":"DeLeve","year":"2009","journal-title":"Hepatology"},{"issue":"8","key":"10.1016\/j.joim.2020.07.006_b0115","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1111\/liv.12160","article-title":"The association between circulating oestradiol levels and severity of liver disease in males with hepatitis B virus infection","volume":"33","author":"Mao","year":"2013","journal-title":"Liver Int"},{"issue":"1","key":"10.1016\/j.joim.2020.07.006_b0120","doi-asserted-by":"crossref","first-page":"11587","DOI":"10.1038\/s41598-018-29800-0","article-title":"Predictive value of the maximum serum creatinine value and growth rate in acute paraquat poisoning patients","volume":"8","author":"Feng","year":"2018","journal-title":"Sci Rep"},{"issue":"3","key":"10.1016\/j.joim.2020.07.006_b0125","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1002\/hep.510230326","article-title":"Toxicity of azathioprine and monocrotaline in murine sinusoidal endothelial cells and hepatocytes: the role of glutathione and relevance to hepatic venoocclusive disease","volume":"23","author":"DeLeve","year":"1996","journal-title":"Hepatology"},{"issue":"9","key":"10.1016\/j.joim.2020.07.006_b0130","doi-asserted-by":"crossref","first-page":"962","DOI":"10.3109\/15563650.2010.527851","article-title":"Sinusoidal obstruction syndrome associated with the ingestion of gynura root","volume":"48","author":"Li","year":"2010","journal-title":"Clin Toxicol (Phila)"},{"issue":"1","key":"10.1016\/j.joim.2020.07.006_b0135","doi-asserted-by":"crossref","first-page":"2239","DOI":"10.1038\/s41598-017-02527-0","article-title":"Time-dependent haemoperfusion after acute paraquat poisoning","volume":"7","author":"Wang","year":"2017","journal-title":"Sci Rep"},{"issue":"1","key":"10.1016\/j.joim.2020.07.006_b0140","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1186\/s12876-018-0879-7","article-title":"Risk factors for hepatic veno-occlusive disease caused by Gynura segetum: a retrospective study","volume":"18","author":"Wang","year":"2018","journal-title":"BMC Gastroenterol"},{"issue":"3","key":"10.1016\/j.joim.2020.07.006_b0145","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1111\/j.1872-034X.2011.00918.x","article-title":"Hepatic veno-occlusive disease after taking Gynura Rhizome: the value of multidetector computed tomography in diagnosing the disease and evaluating the clinical therapeutic effect","volume":"42","author":"Wu","year":"2012","journal-title":"Hepatol Res"},{"issue":"4","key":"10.1016\/j.joim.2020.07.006_b0150","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/j.jhep.2010.12.003","article-title":"Herbal medicine hepatotoxicity: a new step with development of specific biomarkers","volume":"54","author":"Larrey","year":"2011","journal-title":"J Hepatol"},{"issue":"6","key":"10.1016\/j.joim.2020.07.006_b0155","first-page":"252","article-title":"Hepatic veno-occlusive disease associated with toxicity of pyrrolizidine alkaloids in herbal preparations","volume":"68","author":"Chen","year":"2010","journal-title":"Neth J Med"}],"container-title":["Journal of Integrative Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2095496420300765?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2095496420300765?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:49:55Z","timestamp":1761864595000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2095496420300765"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":31,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,9]]}},"alternative-id":["S2095496420300765"],"URL":"https:\/\/doi.org\/10.1016\/j.joim.2020.07.006","relation":{},"ISSN":["2095-4964"],"issn-type":[{"type":"print","value":"2095-4964"}],"subject":[],"published":{"date-parts":[[2020,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinical characteristics and outcomes of patients with hepatic veno-occlusive disease induced by Gynura segetum: A retrospective study","name":"articletitle","label":"Article Title"},{"value":"Journal of Integrative Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joim.2020.07.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Shanghai Changhai Hospital. Published by ELSEVIER B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}