{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T11:58:10Z","timestamp":1768823890870,"version":"3.49.0"},"reference-count":20,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,11,1]],"date-time":"2021-11-01T00:00:00Z","timestamp":1635724800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81704013"],"award-info":[{"award-number":["81704013"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Integrative Medicine"],"published-print":{"date-parts":[[2021,11]]},"DOI":"10.1016\/j.joim.2021.10.001","type":"journal-article","created":{"date-parts":[[2021,10,12]],"date-time":"2021-10-12T09:10:16Z","timestamp":1634029816000},"page":"555-560","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Stevens-Johnson syndrome\/toxic epidermal necrolysis successfully treated with Chinese herbal medicine Pi-Yan-Ning: A case report"],"prefix":"10.1016","volume":"19","author":[{"given":"Shu-yi","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qun-wei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liu-mei","family":"Shou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shan-ming","family":"Ruan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhe-hao","family":"Liang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi-jin","family":"Shu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.joim.2021.10.001_b0005","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1007\/s12325-017-0530-y","article-title":"Stevens-Johnson syndrome and toxic epidermal necrolysis: a concise review with a comprehensive summary of therapeutic interventions emphasizing supportive measures","volume":"34","author":"Schneider","year":"2017","journal-title":"Adv Ther"},{"issue":"6","key":"10.1016\/j.joim.2021.10.001_b0010","doi-asserted-by":"crossref","first-page":"e119","DOI":"10.1016\/j.bjps.2016.01.034","article-title":"UK guidelines for the management of Stevens-Johnson syndrome\/toxic epidermal necrolysis in adults 2016","volume":"69","author":"Creamer","year":"2016","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"10.1016\/j.joim.2021.10.001_b0015","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.jclinepi.2017.04.026","article-title":"CARE guidelines for case reports: explanation and elaboration document","volume":"89","author":"Riley","year":"2017","journal-title":"J Clin Epidemiol"},{"issue":"2","key":"10.1016\/j.joim.2021.10.001_b0020","doi-asserted-by":"crossref","first-page":"519","DOI":"10.3892\/etm.2015.2549","article-title":"Clinical characteristics and treatment outcome of Stevens-Johnson syndrome and toxic epidermal necrolysis","volume":"10","author":"Chantaphakul","year":"2015","journal-title":"Exp Ther Med"},{"issue":"1","key":"10.1016\/j.joim.2021.10.001_b0025","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.burns.2016.07.026","article-title":"Steven Johnson syndrome and toxic epidermal necrolysis in a burn unit: a 15-year experience","volume":"43","author":"McCullough","year":"2017","journal-title":"Burns"},{"issue":"6","key":"10.1016\/j.joim.2021.10.001_b0030","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1111\/bjd.12607","article-title":"The role of intravenous immunoglobulin in toxic epidermal necrolysis: a retrospective analysis of 64 patients managed in a specialized centre","volume":"169","author":"Lee","year":"2013","journal-title":"Br J Dermatol"},{"issue":"1","key":"10.1016\/j.joim.2021.10.001_b0035","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.burns.2015.03.012","article-title":"Complications of Stevens-Johnson syndrome beyond the eye and skin","volume":"42","author":"Saeed","year":"2016","journal-title":"Burns"},{"issue":"3","key":"10.1016\/j.joim.2021.10.001_b0040","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.jaad.2015.10.029","article-title":"Cutaneous adverse events (AEs) of anti-programmed cell death (PD)-1 therapy in patients with metastatic melanoma: a single-institution cohort","volume":"74","author":"Hwang","year":"2016","journal-title":"J Am Acad Dermatol"},{"issue":"12","key":"10.1016\/j.joim.2021.10.001_b0045","doi-asserted-by":"crossref","first-page":"2375","DOI":"10.1093\/annonc\/mdv383","article-title":"Toxicities of the anti-PD-1 and anti-PD-L1 immune checkpoint antibodies","volume":"26","author":"Naidoo","year":"2015","journal-title":"Ann Oncol"},{"issue":"1","key":"10.1016\/j.joim.2021.10.001_b0050","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.jep.2012.06.030","article-title":"Effect of Si-Miao-Yong-An on the stability of atherosclerotic plaque in a diet-induced rabbit model","volume":"143","author":"Peng","year":"2012","journal-title":"J Ethnopharmacol"},{"key":"10.1016\/j.joim.2021.10.001_b0055","doi-asserted-by":"crossref","first-page":"990","DOI":"10.3389\/fphar.2019.00990","article-title":"Si-Miao-Yong-An Decoction protects against cardiac hypertrophy and dysfunction by inhibiting platelet aggregation and activation","volume":"10","author":"Su","year":"2019","journal-title":"Front Pharmacol"},{"key":"10.1016\/j.joim.2021.10.001_b0060","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.ijbiomac.2015.06.033","article-title":"Effect of ultrasonic treatment on immunological activities of polysaccharides from adlay","volume":"80","author":"Yao","year":"2015","journal-title":"Int J Biol Macromol"},{"issue":"1","key":"10.1016\/j.joim.2021.10.001_b0065","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.jep.2012.02.009","article-title":"Inhibitory effects of adlay bran (Coix lachryma-jobi L. var. ma-yuen Stapf) on chemical mediator release and cytokine production in rat basophilic leukemia cells","volume":"141","author":"Chen","year":"2012","journal-title":"J Ethnopharmacol"},{"key":"10.1016\/j.joim.2021.10.001_b0070","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.fitote.2015.07.006","article-title":"Anti-inflammatory dimeric furanocoumarins from the roots of Angelica dahurica","volume":"105","author":"Yang","year":"2015","journal-title":"Fitoterapia"},{"issue":"1","key":"10.1016\/j.joim.2021.10.001_b0075","doi-asserted-by":"crossref","first-page":"874","DOI":"10.3892\/etm.2017.4569","article-title":"Coumarins from the roots of Angelica dahurica cause anti-allergic inflammation","volume":"14","author":"Li","year":"2017","journal-title":"Exp Ther Med"},{"key":"10.1016\/j.joim.2021.10.001_b0080","doi-asserted-by":"crossref","first-page":"18080","DOI":"10.1038\/srep18080","article-title":"Discovery of anti-inflammatory ingredients in Chinese herbal formula Kouyanqing Granule based on relevance analysis between chemical characters and biological effects","volume":"5","author":"Liu","year":"2015","journal-title":"Sci Rep"},{"issue":"3","key":"10.1016\/j.joim.2021.10.001_b0085","first-page":"1445","article-title":"Liquiritin suppresses UVB\u2013induced skin injury through prevention of inflammation, oxidative stress and apoptosis through the TLR4\/MyD88\/NF-\u03baB and MAPK\/caspase signaling pathways","volume":"42","author":"Li","year":"2018","journal-title":"Int J Mol Med"},{"issue":"6","key":"10.1016\/j.joim.2021.10.001_b0090","doi-asserted-by":"crossref","first-page":"4613","DOI":"10.3892\/mmr.2016.5107","article-title":"Hyperoside protects human primary melanocytes against H2O2-induced oxidative damage","volume":"13","author":"Yang","year":"2016","journal-title":"Mol Med Rep"},{"key":"10.1016\/j.joim.2021.10.001_b0095","first-page":"599","article-title":"Isolation, characterization and hypolipidemic activity of ferulic acid in high-fat-diet-induced hyperlipidemia in laboratory rats","volume":"15","author":"Jain","year":"2016","journal-title":"EXCLI J"},{"issue":"1","key":"10.1016\/j.joim.2021.10.001_b0100","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.jep.2013.02.017","article-title":"Glycyrrhizic acid as the antiviral component of Glycyrrhiza uralensis Fisch. against coxsackievirus A16 and enterovirus 71 of hand foot and mouth disease","volume":"147","author":"Wang","year":"2013","journal-title":"J Ethnopharmacol"}],"container-title":["Journal of Integrative Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S209549642100087X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S209549642100087X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:52:07Z","timestamp":1761864727000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S209549642100087X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11]]},"references-count":20,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["S209549642100087X"],"URL":"https:\/\/doi.org\/10.1016\/j.joim.2021.10.001","relation":{},"ISSN":["2095-4964"],"issn-type":[{"value":"2095-4964","type":"print"}],"subject":[],"published":{"date-parts":[[2021,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Stevens-Johnson syndrome\/toxic epidermal necrolysis successfully treated with Chinese herbal medicine Pi-Yan-Ning: A case report","name":"articletitle","label":"Article Title"},{"value":"Journal of Integrative Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joim.2021.10.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Shanghai Yueyang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}