{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T15:58:38Z","timestamp":1791907118019,"version":"4.3.4"},"reference-count":129,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["472153\/2013-7"],"award-info":[{"award-number":["472153\/2013-7"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004263","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado do Rio Grande do Sul","doi-asserted-by":"publisher","award":["PPSUS 1422-7\/2017"],"award-info":[{"award-number":["PPSUS 1422-7\/2017"]}],"id":[{"id":"10.13039\/501100004263","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004263","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado do Rio Grande do Sul","doi-asserted-by":"publisher","award":["PRONEM 246-0\/2016"],"award-info":[{"award-number":["PRONEM 246-0\/2016"]}],"id":[{"id":"10.13039\/501100004263","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006506","name":"Minist\u00e9rio da Sa\u00fade","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006506","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001409","name":"Department of Science and Technology, Ministry of Science and Technology, India","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001409","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Integrative Medicine"],"published-print":{"date-parts":[[2022,9]]},"DOI":"10.1016\/j.joim.2022.07.002","type":"journal-article","created":{"date-parts":[[2022,7,11]],"date-time":"2022-07-11T02:26:15Z","timestamp":1657506375000},"page":"385-395","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"title":["Effects of bioactive compounds from Pleurotus mushrooms on COVID-19 risk factors associated with the cardiovascular system"],"prefix":"10.1016","volume":"20","author":[{"given":"Eduardo Echer","family":"dos Reis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo Cavalheiro","family":"Schenkel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marli","family":"Camassola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.joim.2022.07.002_b0005","doi-asserted-by":"crossref","first-page":"355","DOI":"10.3109\/07388551.2014.887649","article-title":"Therapeutic potential of culinary-medicinal mushrooms for the management of neurodegenerative diseases: diversity, metabolite, and mechanism","volume":"35","author":"Phan","year":"2015","journal-title":"Crit Rev Biotechnol"},{"issue":"6","key":"10.1016\/j.joim.2022.07.002_b0010","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/j.biotechadv.2011.05.003","article-title":"Bioactive proteins from mushrooms","volume":"29","author":"Xu","year":"2011","journal-title":"Biotechnol Adv"},{"issue":"1","key":"10.1016\/j.joim.2022.07.002_b0015","doi-asserted-by":"crossref","first-page":"3","DOI":"10.2174\/1573401314666181015111724","article-title":"Nutraceutical potential and processing aspects of oyster mushrooms (Pleurotus species)","volume":"16","author":"Kumar","year":"2020","journal-title":"Curr Nutr Food Sci"},{"key":"10.1016\/j.joim.2022.07.002_b0020","series-title":"Introductory mycology","author":"Alexopoulos","year":"1996"},{"issue":"2","key":"10.1016\/j.joim.2022.07.002_b0025","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1590\/S1516-89132010000200019","article-title":"Morphological and molecular identification of four Brazilian commercial isolates of Pleurotus spp. and cultivation on corncob","volume":"53","author":"Junior","year":"2010","journal-title":"Brazilian Arch Biol Technol"},{"issue":"4","key":"10.1016\/j.joim.2022.07.002_b0030","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.riam.2010.12.001","article-title":"Search for new naturally occurring strains of Pleurotus to improve yields: Pleurotus albidus as a novel proposed species for mushroom production","volume":"28","author":"Lechner","year":"2011","journal-title":"Rev Iberoam Micol"},{"key":"10.1016\/j.joim.2022.07.002_b0035","series-title":"Edible and medicinal mushrooms: technology and applications","first-page":"5","article-title":"Current overview of mushroom production in the world","author":"Royse","year":"2017"},{"issue":"3","key":"10.1016\/j.joim.2022.07.002_b0040","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1039\/C7FO01747B","article-title":"Circular reuse of bio-resources: the role of Pleurotus spp. in the development of functional foods","volume":"9","author":"Lavelli","year":"2018","journal-title":"Food Funct"},{"issue":"1","key":"10.1016\/j.joim.2022.07.002_b0045","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1080\/07388550802688821","article-title":"Biology of Pleurotus eryngii and role in biotechnological processes: a review","volume":"29","author":"Staji\u0107","year":"2009","journal-title":"Crit Rev Biotechnol"},{"key":"10.1016\/j.joim.2022.07.002_b0050","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.cofs.2017.04.002","article-title":"The beneficial role of edible mushrooms in human health","volume":"14","author":"Roncero-Ramos","year":"2017","journal-title":"Curr Opin Food Sci"},{"issue":"3","key":"10.1016\/j.joim.2022.07.002_b0055","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.foodchem.2004.08.022","article-title":"Distribution of ergosterol in different tissues of mushrooms and its effect on the conversion of ergosterol to vitamin D2 by UV irradiation","volume":"92","author":"Jasinghe","year":"2005","journal-title":"Food Chem"},{"key":"10.1016\/j.joim.2022.07.002_b0060","doi-asserted-by":"crossref","first-page":"124988","DOI":"10.1016\/j.foodchem.2019.124988","article-title":"Chemical features and bioactivity of grain flours colonized by macrofungi as a strategy for nutritional enrichment","volume":"297","author":"Stoffel","year":"2019","journal-title":"Food Chem"},{"issue":"10","key":"10.1016\/j.joim.2022.07.002_b0065","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1039\/C4NP00060A","article-title":"Fungal natural products in research and development","volume":"31","author":"Schueffler","year":"2014","journal-title":"Nat Prod Rep"},{"key":"10.1016\/j.joim.2022.07.002_b0070","doi-asserted-by":"crossref","first-page":"139330","DOI":"10.1016\/j.scitotenv.2020.139330","article-title":"\u03b2-Glucan extracts from the same edible shiitake mushroom Lentinus edodes produce differential in vitro immunomodulatory and pulmonary cytoprotective effects\u2014implications for coronavirus disease (COVID-19) immunotherapies","volume":"732","author":"Murphy","year":"2020","journal-title":"Sci Total Environ"},{"issue":"4","key":"10.1016\/j.joim.2022.07.002_b0075","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1038\/s41569-020-00437-9","article-title":"Lifestyle interventions for the prevention and treatment of hypertension","volume":"18","author":"Valenzuela","year":"2021","journal-title":"Nat Rev Cardiol"},{"issue":"3","key":"10.1016\/j.joim.2022.07.002_b0080","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.exger.2006.10.006","article-title":"Protective effect of an extract of the oyster mushroom, Pleurotus ostreatus, on antioxidants of major organs of aged rats","volume":"42","author":"Jayakumar","year":"2007","journal-title":"Exp Gerontol"},{"key":"10.1016\/j.joim.2022.07.002_b0085","doi-asserted-by":"crossref","first-page":"127173","DOI":"10.1016\/j.foodchem.2020.127173","article-title":"Obtaining extracts rich in antioxidant polysaccharides from the edible mushroom Pleurotus ostreatus using binary system with hot water and supercritical CO2","volume":"330","author":"Barbosa","year":"2020","journal-title":"Food Chem"},{"issue":"5","key":"10.1016\/j.joim.2022.07.002_b0090","doi-asserted-by":"crossref","first-page":"331","DOI":"10.3390\/pathogens9050331","article-title":"The human coronavirus disease COVID-19: its origin, characteristics, and insights into potential drugs and its mechanisms","volume":"9","author":"Alanagreh","year":"2020","journal-title":"Pathogens"},{"key":"10.1016\/j.joim.2022.07.002_b0095","doi-asserted-by":"crossref","first-page":"60","DOI":"10.11606\/s1518-8787.2020054002481","article-title":"A brief-review of the risk factors for COVID-19 severity","volume":"54","author":"Rod","year":"2020","journal-title":"Rev Saude Publica"},{"issue":"13","key":"10.1016\/j.joim.2022.07.002_b0100","doi-asserted-by":"crossref","first-page":"1239","DOI":"10.1001\/jama.2020.2648","article-title":"Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72314 cases from the Chinese Center for Disease Control and Prevention","volume":"323","author":"Wu","year":"2020","journal-title":"JAMA"},{"issue":"10223","key":"10.1016\/j.joim.2022.07.002_b0105","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0140-6736(20)30183-5","article-title":"Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China","volume":"395","author":"Huang","year":"2020","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.joim.2022.07.002_b0110","first-page":"687","article-title":"Prevalence of systemic arterial hypertension and associated factors among adults from the semi-arid region of Pernambuco, Brazil","volume":"113","author":"Santiago","year":"2019","journal-title":"Arq Bras Cardiol"},{"issue":"2","key":"10.1016\/j.joim.2022.07.002_b0115","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.tifs.2014.06.002","article-title":"Therapeutic potential of mushrooms in preventing and ameliorating hypertension","volume":"39","author":"Mohamed Yahaya","year":"2014","journal-title":"Trends Food Sci Technol"},{"issue":"17","key":"10.1016\/j.joim.2022.07.002_b0120","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1007\/s40265-014-0306-5","article-title":"Updated national and international hypertension guidelines: a review of current recommendations","volume":"74","author":"Kjeldsen","year":"2014","journal-title":"Drugs"},{"issue":"2","key":"10.1016\/j.joim.2022.07.002_b0125","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1152\/physrev.00056.2003","article-title":"Links between dietary salt intake, renal salt handling, blood pressure, and cardiovascular diseases","volume":"85","author":"Meneton","year":"2005","journal-title":"Physiol Rev"},{"issue":"2","key":"10.1016\/j.joim.2022.07.002_b0130","first-page":"35","article-title":"Mushroom nutraceuticals for improved nutrition and better human health: a review","volume":"5","author":"Rathore","year":"2017","journal-title":"Pharma Nutr"},{"issue":"13","key":"10.1016\/j.joim.2022.07.002_b0135","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1016\/0024-3205(86)90169-4","article-title":"Hypotensive and renal effects of an extract of the edible mushroom Pleurotus sajor-caju","volume":"38","author":"Tam","year":"1986","journal-title":"Life Sci"},{"issue":"2","key":"10.1016\/j.joim.2022.07.002_b0140","doi-asserted-by":"crossref","first-page":"383","DOI":"10.21010\/ajtcam.v14i2.39","article-title":"Structural characteristics and antihypertensive effects of angiotensin-I-converting enzyme inhibitory peptides in the renin-angiotensin and kallikrein kinin systems","volume":"14","author":"Manoharan","year":"2017","journal-title":"African J Tradit Complement Altern Med"},{"issue":"12","key":"10.1016\/j.joim.2022.07.002_b0145","doi-asserted-by":"crossref","first-page":"675","DOI":"10.5650\/jos.57.675","article-title":"Antihypertensive effect of Pleurotus nebrodensis in spontaneously hypertensive rats","volume":"57","author":"Miyazawa","year":"2008","journal-title":"J Oleo Sci"},{"issue":"2","key":"10.1016\/j.joim.2022.07.002_b0150","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.bionut.2014.02.006","article-title":"Blood pressure lowering activity of a flavonoid and phytosterol rich extract of the sclerotia of Pleurotus tuberregium (Fr) Sing in salt-loaded rats","volume":"4","author":"Ikewuchi","year":"2014","journal-title":"Biomed Prev Nutr"},{"issue":"8","key":"10.1016\/j.joim.2022.07.002_b0155","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1271\/bbb.69.1603","article-title":"A phytochemical in the edible Tamogi-take mushroom (Pleurotus cornucopiae), D-mannitol, inhibits ACE activity and lowers the blood pressure of spontaneously hypertensive rats","volume":"69","author":"Hagiwara","year":"2005","journal-title":"Biosci Biotechnol Biochem"},{"issue":"2","key":"10.1016\/j.joim.2022.07.002_b0160","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.foodchem.2011.01.010","article-title":"Characterisation of a new antihypertensive angiotensin I-converting enzyme inhibitory peptide from Pleurotus cornucopiae","volume":"127","author":"Jang","year":"2011","journal-title":"Food Chem"},{"issue":"6801","key":"10.1016\/j.joim.2022.07.002_b0165","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1038\/35025203","article-title":"Atherosclerosis","volume":"407","author":"Lusis","year":"2000","journal-title":"Nature"},{"issue":"2","key":"10.1016\/j.joim.2022.07.002_b0170","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1007\/s13105-012-0215-6","article-title":"Antihypercholesterolemic and antioxidative effects of an extract of the oyster mushroom, Pleurotus ostreatus, and its major constituent, chrysin, in Triton WR-1339-induced hypercholesterolemic rats","volume":"69","author":"Anandhi","year":"2013","journal-title":"J Physiol Biochem"},{"issue":"3","key":"10.1016\/j.joim.2022.07.002_b0175","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/S0899-9007(97)00471-1","article-title":"Dose- and time-dependent hypocholesterolemic effect of oyster mushroom (Pleurotus ostreatus) in rats","volume":"14","author":"Bobek","year":"1998","journal-title":"Nutrition"},{"issue":"5","key":"10.1016\/j.joim.2022.07.002_b0180","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1002\/(SICI)1521-3803(19991001)43:5<339::AID-FOOD339>3.0.CO;2-5","article-title":"Hypocholesterolemic and antiatherogenic effect of oyster mushroom (Pleurotus ostreatus) in rabbits","volume":"43","author":"Bobek","year":"1999","journal-title":"Nahrung"},{"issue":"5","key":"10.1016\/j.joim.2022.07.002_b0185","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.nutres.2008.03.010","article-title":"Antiatherosclerotic effect of the edible mushrooms Pleurotus eryngii (Eringi), Grifola frondosa (Maitake), and Hypsizygus marmoreus (Bunashimeji) in apolipoprotein E-deficient mice","volume":"28","author":"Mori","year":"2008","journal-title":"Nutr Res"},{"issue":"1","key":"10.1016\/j.joim.2022.07.002_b0190","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1186\/s12906-017-1892-z","article-title":"Antihyperlipidaemic and hepatoprotective activities of acidic and enzymatic hydrolysis exopolysaccharides from Pleurotus eryngii SI-04","volume":"17","author":"Zhang","year":"2017","journal-title":"BMC Complement Altern Med"},{"issue":"2","key":"10.1016\/j.joim.2022.07.002_b0195","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/j.jep.2013.09.002","article-title":"Moderation of hematological and plasma biochemical indices of sub-chronic salt-loaded rats by aqueous extract of the sclerotia of Pleurotus tuberregium (Fr) Sing\u2019s: implications for the reduction of cardiovascular risk","volume":"150","author":"Ikewuchi","year":"2013","journal-title":"J Ethnopharmacol"},{"key":"10.1016\/j.joim.2022.07.002_b0200","doi-asserted-by":"crossref","first-page":"101014","DOI":"10.1016\/j.eujim.2019.101014","article-title":"Preparation and characterization of nano statins using oyster mushroom (Pleurotus sajor-caju): a new strategy to reduce toxicity and enhance efficacy for the treatment of cardiovascular disease","volume":"33","author":"Mehra","year":"2020","journal-title":"Eur J Integr Med"},{"issue":"6 Pt 1","key":"10.1016\/j.joim.2022.07.002_b0205","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1016\/j.biotechadv.2015.04.001","article-title":"Lovastatin production: from molecular basis to industrial process optimization","volume":"33","author":"Mulder","year":"2015","journal-title":"Biotechnol Adv"},{"key":"10.1016\/j.joim.2022.07.002_b0210","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.carbpol.2017.08.009","article-title":"Anti-hyperlipidemic and antioxidant effects of alkali-extractable mycelia polysaccharides by Pleurotus eryngii var. tuolensis","volume":"175","author":"Ren","year":"2017","journal-title":"Carbohydr Polym"},{"issue":"Pt 2","key":"10.1016\/j.joim.2022.07.002_b0215","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1258\/acb.2007.007177","article-title":"HDL-cholesterol modulation and its impact on the management of cardiovascular risk","volume":"45","author":"Ferns","year":"2008","journal-title":"Ann Clin Biochem"},{"issue":"1","key":"10.1016\/j.joim.2022.07.002_b0220","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1161\/01.CIR.79.1.8","article-title":"High-density lipoprotein cholesterol and cardiovascular disease. Four prospective American studies","volume":"79","author":"Gordon","year":"1989","journal-title":"Circulation"},{"issue":"2","key":"10.1016\/j.joim.2022.07.002_b0225","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1615\/IntJMedMushrooms.v19.i2.20","article-title":"In vitro antioxidant and in vivo hypolipidemic effects of the king oyster culinary-medicinal mushroom, Pleurotus eryngii var. ferulae DDL01 (Agaricomycetes), in rats with high-fat diet-induced fatty liver and hyperlipidemia","volume":"19","author":"Choi","year":"2017","journal-title":"Int J Med Mushrooms"},{"key":"10.1016\/j.joim.2022.07.002_b0230","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.ijbiomac.2019.01.164","article-title":"Characterization and anti-hyperlipidemia effects of enzymatic residue polysaccharides from Pleurotus ostreatus","volume":"129","author":"Dong","year":"2019","journal-title":"Int J Biol Macromol"},{"key":"10.1016\/j.joim.2022.07.002_b0235","unstructured":"Bobek P, Galbav\u00fd S. The oyster mushroom (Pleurotus ostreatus) effectively prevents the development of atherosclerosis in rabbits. Ceska Slov Farm 1999;48(5):226\u201330 [Slovak]."},{"issue":"1","key":"10.1016\/j.joim.2022.07.002_b0240","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1152\/physrev.00018.2001","article-title":"Free radicals in the physiological control of cell function","volume":"82","author":"Dr\u00f6ge","year":"2002","journal-title":"Physiol Rev"},{"issue":"Suppl 2","key":"10.1016\/j.joim.2022.07.002_b0245","doi-asserted-by":"crossref","first-page":"S181","DOI":"10.2337\/dc08-s245","article-title":"Possible role of oxidative stress in the pathogenesis of hypertension","volume":"31","author":"Ceriello","year":"2008","journal-title":"Diabetes Care"},{"issue":"4","key":"10.1016\/j.joim.2022.07.002_b0250","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1007\/s00253-007-0865-4","article-title":"A polysaccharide-peptide complex from abalone mushroom (Pleurotus abalonus) fruiting bodies increases activities and gene expression of antioxidant enzymes and reduces lipid peroxidation in senescence-accelerated mice","volume":"75","author":"Li","year":"2007","journal-title":"Appl Microbiol Biotechnol"},{"issue":"1","key":"10.1016\/j.joim.2022.07.002_b0255","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cbi.2005.12.009","article-title":"Free radicals, metals and antioxidants in oxidative stress-induced cancer","volume":"160","author":"Valko","year":"2006","journal-title":"Chem Biol Interact"},{"issue":"3","key":"10.1016\/j.joim.2022.07.002_b0260","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1038\/s41569-019-0260-8","article-title":"NADPH oxidases and oxidase crosstalk in cardiovascular diseases: novel therapeutic targets","volume":"17","author":"Zhang","year":"2020","journal-title":"Nat Rev Cardiol"},{"key":"10.1016\/j.joim.2022.07.002_b0265","doi-asserted-by":"crossref","first-page":"678741","DOI":"10.1155\/2014\/678741","article-title":"Oxidative stress and antioxidant strategies in cardiovascular disease","volume":"2014","author":"Bell\u00f3-Klein","year":"2014","journal-title":"Oxid Med Cell Longev"},{"key":"10.1016\/j.joim.2022.07.002_b0270","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1007\/978-1-4419-7347-4_18","article-title":"Methods for the determination of antioxidant capacity in food and raw materials","volume":"698","author":"Litescu","year":"2010","journal-title":"Adv Exp Med Biol"},{"issue":"8","key":"10.1016\/j.joim.2022.07.002_b0275","doi-asserted-by":"crossref","first-page":"2969","DOI":"10.3390\/nu5082969","article-title":"Plasma and dietary antioxidant status as cardiovascular disease risk factors: a review of human studies","volume":"5","author":"Wang","year":"2013","journal-title":"Nutrients"},{"issue":"1\u20132","key":"10.1016\/j.joim.2022.07.002_b0280","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.mce.2014.04.010","article-title":"Cardioprotective effects of thyroid hormones in a rat model of myocardial infarction are associated with oxidative stress reduction","volume":"391","author":"Castro","year":"2014","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.joim.2022.07.002_b0285","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.fct.2012.09.021","article-title":"A review on antioxidants, prooxidants and related controversy: natural and synthetic compounds, screening and analysis methodologies and future perspectives","volume":"51","author":"Carocho","year":"2013","journal-title":"Food Chem Toxicol"},{"key":"10.1016\/j.joim.2022.07.002_b0290","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.biortech.2016.01.121","article-title":"Evaluation of productivity and antioxidant profile of solid-state cultivated macrofungi Pleurotus albidus and Pycnoporus sanguineus","volume":"207","author":"Gambato","year":"2016","journal-title":"Bioresour Technol"},{"issue":"2","key":"10.1016\/j.joim.2022.07.002_b0295","doi-asserted-by":"crossref","first-page":"89","DOI":"10.59566\/IJBS.2008.4089","article-title":"Free radicals, antioxidants in disease and health","volume":"4","author":"Pham-Huy","year":"2008","journal-title":"Int J Biomed Sci"},{"issue":"9","key":"10.1016\/j.joim.2022.07.002_b0300","doi-asserted-by":"crossref","first-page":"685","DOI":"10.2165\/00002512-200118090-00004","article-title":"Role of free radicals in the neurodegenerative diseases","volume":"18","author":"Halliwell","year":"2001","journal-title":"Drugs Aging"},{"issue":"12","key":"10.1016\/j.joim.2022.07.002_b0305","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1080\/1071576021000049890","article-title":"Amyloid \u03b2-peptide (1\u201342)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer\u2019s disease brain. A review","volume":"36","author":"Butterfield","year":"2002","journal-title":"Free Radic Res"},{"issue":"1\u20133","key":"10.1016\/j.joim.2022.07.002_b0310","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0014-2999(01)01320-6","article-title":"Oxidative stress and lung inflammation in airways disease","volume":"429","author":"MacNee","year":"2001","journal-title":"Eur J Pharmacol"},{"issue":"4","key":"10.1016\/j.joim.2022.07.002_b0315","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1089\/ars.2007.1961","article-title":"Redox-based therapeutics for lung diseases","volume":"10","author":"Hoshino","year":"2008","journal-title":"Antioxid Redox Signal"},{"issue":"1","key":"10.1016\/j.joim.2022.07.002_b0320","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1093\/aje\/kwj007","article-title":"Serum antioxidants, inflammation, and total mortality in older women","volume":"163","author":"Walston","year":"2006","journal-title":"Am J Epidemiol"},{"issue":"1","key":"10.1016\/j.joim.2022.07.002_b0325","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.biocel.2006.07.001","article-title":"Free radicals and antioxidants in normal physiological functions and human disease","volume":"39","author":"Valko","year":"2007","journal-title":"Int J Biochem Cell Biol"},{"issue":"2","key":"10.1016\/j.joim.2022.07.002_b0330","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0929-7855(96)00555-X","article-title":"Preventive effects of two PAF-antgonists, PMS 536 and PMS 549, on cyclosporin-induced LLC-PK1 oxidative injury","volume":"15","author":"Massicot","year":"1997","journal-title":"J Lipid Mediat Cell Signal"},{"issue":"2","key":"10.1016\/j.joim.2022.07.002_b0335","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0039-6257(00)00140-5","article-title":"The role of oxidative stress in the pathogenesis of age-related macular degeneration","volume":"45","author":"Beatty","year":"2000","journal-title":"Surv Ophthalmol"},{"key":"10.1016\/j.joim.2022.07.002_b0340","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1159\/000082771","article-title":"Nutritional supplementation to prevent cataract formation","volume":"38","author":"Meyer","year":"2005","journal-title":"Dev Ophthalmol"},{"issue":"10","key":"10.1016\/j.joim.2022.07.002_b0345","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.2174\/0929867053764635","article-title":"Metals, toxicity and oxidative stress","volume":"12","author":"Valko","year":"2005","journal-title":"Curr Med Chem"},{"key":"10.1016\/j.joim.2022.07.002_b0350","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.carbpol.2015.06.076","article-title":"A polysaccharide (PNPA) from Pleurotus nebrodensis offers cardiac protection against ischemia-reperfusion injury in rats","volume":"133","author":"Yan","year":"2015","journal-title":"Carbohydr Polym"},{"issue":"Pt 1","key":"10.1016\/j.joim.2022.07.002_b0355","first-page":"447","article-title":"A polysaccharide (PNPA) from Pleurotus nebrodensis ameliorates hepatic ischemic\/reperfusion (I\/R) injury in rats","volume":"105","author":"Wang","year":"2017","journal-title":"Int J Biol Macromol"},{"key":"10.1016\/j.joim.2022.07.002_b0360","doi-asserted-by":"crossref","first-page":"851","DOI":"10.2147\/TCRM.S107635","article-title":"The role of inflammation in cardiovascular diseases: the predictive value of neutrophil-lymphocyte ratio as a marker in peripheral arterial disease","volume":"12","author":"Paquissi","year":"2016","journal-title":"Ther Clin Risk Manag"},{"issue":"6","key":"10.1016\/j.joim.2022.07.002_b0365","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1038\/s41577-020-0311-8","article-title":"The trinity of COVID-19: immunity, inflammation and intervention","volume":"20","author":"Tay","year":"2020","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.joim.2022.07.002_b0370","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/j.foodchem.2014.05.110","article-title":"Antioxidant and antibacterial activities of sulphated polysaccharides from Pleurotus eryngii and Streptococcus thermophilus ASCC 1275","volume":"165","author":"Li","year":"2014","journal-title":"Food Chem"},{"key":"10.1016\/j.joim.2022.07.002_b0375","doi-asserted-by":"crossref","unstructured":"Gambato G, Pav\u00e3o EM, Chilanti G, Fontana RC, Salvador M, Camassola M. Pleurotus albidus modulates mitochondrial metabolism disrupted by hyperglycaemia in EA.hy926 endothelial cells. Biomed Res Int 2018;2018:2859787.","DOI":"10.1155\/2018\/2859787"},{"issue":"3","key":"10.1016\/j.joim.2022.07.002_b0380","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/j.foodchem.2011.03.036","article-title":"Protective effect of two edible mushrooms against oxidative cell damage and their phenolic composition","volume":"128","author":"Oke","year":"2011","journal-title":"Food Chem"},{"issue":"2\u20133","key":"10.1016\/j.joim.2022.07.002_b0385","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.cbi.2008.08.006","article-title":"Pleurotus ostreatus, an oyster mushroom, decreases the oxidative stress induced by carbon tetrachloride in rat kidneys, heart and brain","volume":"176","author":"Jayakumar","year":"2008","journal-title":"Chem Biol Interact"},{"issue":"4","key":"10.1016\/j.joim.2022.07.002_b0390","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/j.foodres.2011.03.015","article-title":"In-vitro and in-vivo antioxidant effects of the oyster mushroom Pleurotus ostreatus","volume":"44","author":"Jayakumar","year":"2011","journal-title":"Food Res Int"},{"issue":"5","key":"10.1016\/j.joim.2022.07.002_b0395","doi-asserted-by":"crossref","first-page":"e36320","DOI":"10.1371\/journal.pone.0036320","article-title":"Overfeeding reduces insulin sensitivity and increases oxidative stress, without altering markers of mitochondrial content and function in humans","volume":"7","author":"Samocha-Bonet","year":"2012","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.joim.2022.07.002_b0400","doi-asserted-by":"crossref","first-page":"646","DOI":"10.3109\/13880209.2013.863948","article-title":"Pleurotus ostreatus, an edible mushroom, enhances glucose 6-phosphate dehydrogenase, ascorbate peroxidase and reduces xanthine dehydrogenase in major organs of aged rats","volume":"52","author":"Thomas","year":"2014","journal-title":"Pharm Biol"},{"key":"10.1016\/j.joim.2022.07.002_b0405","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s13225-012-0187-4","article-title":"Medicinal mushrooms in prevention and control of diabetes mellitus","volume":"56","author":"De Silva","year":"2012","journal-title":"Fungal Divers"},{"key":"10.1016\/j.joim.2022.07.002_b0410","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.njas.2012.03.003","article-title":"Nutritional qualities and antioxidant activity of three edible oyster mushrooms (Pleurotus spp.).","volume":"72\u201373","author":"Khatun","year":"2015","journal-title":"NJAS\u2013Wageningen J Life Sci"},{"issue":"4","key":"10.1016\/j.joim.2022.07.002_b0415","doi-asserted-by":"crossref","first-page":"291","DOI":"10.5941\/MYCO.2016.44.4.291","article-title":"Evaluation of antioxidant, anti-cholinesterase, and anti-inflammatory effects of culinary mushroom Pleurotus pulmonarius","volume":"44","author":"Nguyen","year":"2016","journal-title":"Mycobiology"},{"issue":"1\u20133","key":"10.1016\/j.joim.2022.07.002_b0420","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.ejphar.2008.08.028","article-title":"Anti-inflammatory and analgesic properties in a rodent model of a (1\u21923), (1\u21926)-linked \u03b2-glucan isolated from Pleurotus pulmonarius","volume":"597","author":"Smiderle","year":"2008","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.joim.2022.07.002_b0425","doi-asserted-by":"crossref","unstructured":"Castro-Alves VC, do Nascimento JRO. \u03b1- and \u03b2-d-Glucans from the edible mushroom Pleurotus albidus differentially regulate lipid-induced inflammation and foam cell formation in human macrophage-like THP-1 cells. Int J Biol Macromol 2018;111:1222\u20138.","DOI":"10.1016\/j.ijbiomac.2018.01.131"},{"key":"10.1016\/j.joim.2022.07.002_b0430","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.ijbiomac.2017.01.043","article-title":"Antioxidant, antitumor and immunostimulatory activities of the polypeptide from Pleurotus eryngii mycelium","volume":"97","author":"Sun","year":"2017","journal-title":"Int J Biol Macromol"},{"issue":"3","key":"10.1016\/j.joim.2022.07.002_b0435","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1017\/S0007114509991760","article-title":"Orally administered glucans from the edible mushroom Pleurotus pulmonarius reduce acute inflammation in dextran sulfate sodium-induced experimental colitis","volume":"103","author":"Lavi","year":"2010","journal-title":"Br J Nutr"},{"key":"10.1016\/j.joim.2022.07.002_b0440","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/j.ijbiomac.2018.10.157","article-title":"Pleurotus citrinopileatus polysaccharide stimulates anti-inflammatory properties during monocyte-to-macrophage differentiation","volume":"122","author":"Minato","year":"2019","journal-title":"Int J Biol Macromol"},{"issue":"1","key":"10.1016\/j.joim.2022.07.002_b0445","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1002\/ptr.1355","article-title":"Methanol extract of the oyster mushroom, Pleurotus florida, inhibits inflammation and platelet aggregation","volume":"18","author":"Jose","year":"2004","journal-title":"Phyther Res"},{"issue":"4","key":"10.1016\/j.joim.2022.07.002_b0450","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1615\/IntJMedMushr.v14.i4.20","article-title":"Oral hypoglycemic activity of culinary-medicinal mushrooms Pleurotus ostreatus and P. cystidiosus (higher basidiomycetes) in normal and alloxan-induced diabetic Wistar rats","volume":"14","author":"Jayasuriya","year":"2012","journal-title":"Int J Med Mushrooms"},{"key":"10.1016\/j.joim.2022.07.002_b0455","doi-asserted-by":"crossref","unstructured":"Kanagasabapathy G, Kuppusamy UR, Malek SNA, Abdulla MA, Chua KH, Sabaratnam V. Glucan-rich polysaccharides from Pleurotus sajor-caju (Fr.) Singer prevents glucose intolerance, insulin resistance and inflammation in C57BL\/6J mice fed a high-fat diet. BMC Complement Altern Med 2012;12:261.","DOI":"10.1186\/1472-6882-12-261"},{"key":"10.1016\/j.joim.2022.07.002_b0460","doi-asserted-by":"crossref","first-page":"856381","DOI":"10.1155\/2012\/856381","article-title":"Pleurotus tuber-regium polysaccharides attenuate hyperglycemia and oxidative stress in experimental diabetic rats","volume":"2012","author":"Huang","year":"2012","journal-title":"Evid Based Complement Altern Med"},{"key":"10.1016\/j.joim.2022.07.002_b0465","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.ijbiomac.2018.01.009","article-title":"Antioxidation, anti-hyperglycaemia and renoprotective effects of extracellular polysaccharides from Pleurotus eryngii SI-04","volume":"111","author":"Zhang","year":"2018","journal-title":"Int J Biol Macromol"},{"issue":"2","key":"10.1016\/j.joim.2022.07.002_b0470","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1111\/1541-4337.12255","article-title":"Antimicrobials from mushrooms for assuring food safety","volume":"16","author":"Shen","year":"2017","journal-title":"Compr Rev Food Sci Food Saf"},{"issue":"12","key":"10.1016\/j.joim.2022.07.002_b0475","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.1016\/j.fct.2006.06.025","article-title":"Antioxidant activity of the oyster mushroom, Pleurotus ostreatus, on CCl4-induced liver injury in rats","volume":"44","author":"Jayakumar","year":"2006","journal-title":"Food Chem Toxicol"},{"key":"10.1016\/j.joim.2022.07.002_b0480","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1016\/j.carbpol.2014.04.074","article-title":"Purification and antioxidant activities of intracellular zinc polysaccharides from Pleurotus cornucopiae SS-03","volume":"111","author":"Zhang","year":"2014","journal-title":"Carbohydr Polym"},{"issue":"5","key":"10.1016\/j.joim.2022.07.002_b0485","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1615\/IntJMedMushrooms.v17.i5.90","article-title":"Antioxidant potential of white oyster culinary-medicinal mushroom, Pleurotus florida (higher Basidiomycetes)","volume":"17","author":"Ganeshpurkar","year":"2015","journal-title":"Int J Med Mushrooms"},{"issue":"2","key":"10.1016\/j.joim.2022.07.002_b0490","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1615\/IntJMedMushrooms.v17.i2.30","article-title":"Determination of lovastatin, \u03b2-glucan, total polyphenols, and antioxidant activity in raw and processed oyster culinary-medicinal mushroom, Pleurotus ostreatus (higher basidiomycetes)","volume":"17","author":"Lam","year":"2015","journal-title":"Int J Med Mushrooms"},{"key":"10.1016\/j.joim.2022.07.002_b0495","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.cbi.2015.06.017","article-title":"Antioxidant and antitumor effects of polysaccharides from the fungus Pleurotus abalonus","volume":"237","author":"Ren","year":"2015","journal-title":"Chem Biol Interact"},{"issue":"2","key":"10.1016\/j.joim.2022.07.002_b0500","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1615\/IntJMedMushrooms.v18.i2.20","article-title":"Protective effect of antioxidant extracts from grey oyster mushroom, Pleurotus pulmonarius (Agaricomycetes), against human low-density lipoprotein oxidation and aortic endothelial cell damage","volume":"18","author":"Abidin","year":"2016","journal-title":"Int J Med Mushrooms"},{"issue":"1","key":"10.1016\/j.joim.2022.07.002_b0505","doi-asserted-by":"crossref","first-page":"386","DOI":"10.4103\/0973-1482.148691","article-title":"Modulatory effect of Pleurotus ostreatus on oxidant\/antioxidant status in 7,12-dimethylbenz (a) anthracene induced mammary carcinoma in experimental rats\u2014a dose-response study","volume":"12","author":"Krishnamoorthy","year":"2016","journal-title":"J Cancer Res Ther"},{"key":"10.1016\/j.joim.2022.07.002_b0510","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.bcab.2016.12.003","article-title":"Antioxidant and antibacterial activities of acetonitrile and hexane extracts of Lentinus tigrinus and Pleurotus djamour","volume":"9","author":"Dulay","year":"2017","journal-title":"Biocatal Agric Biotechnol"},{"key":"10.1016\/j.joim.2022.07.002_b0515","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/j.ijbiomac.2018.04.001","article-title":"Antioxidant and hepatoprotective effects of intracellular mycelium polysaccharides from Pleurotus geesteranus against alcoholic liver diseases","volume":"114","author":"Song","year":"2018","journal-title":"Int J Biol Macromol"},{"key":"10.1016\/j.joim.2022.07.002_b0520","doi-asserted-by":"crossref","unstructured":"Rodrigues Barbosa J, Dos Santos Freitas MM, da Silva Martins LH, de Carvalho RN. Polysaccharides of mushroom Pleurotus spp.: new extraction techniques, biological activities and development of new technologies. Carbohydr Polym 2020;229:115550.","DOI":"10.1016\/j.carbpol.2019.115550"},{"key":"10.1016\/j.joim.2022.07.002_b0525","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1186\/1475-2891-10-52","article-title":"Anti-inflammatory activity of edible oyster mushroom is mediated through the inhibition of NF-\u03baB and AP-1 signaling","volume":"10","author":"Jedinak","year":"2011","journal-title":"Nutr J"},{"issue":"4","key":"10.1016\/j.joim.2022.07.002_b0530","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1007\/s00296-009-1258-z","article-title":"The effects of \u03b2-glucan isolated from Pleurotus ostreatus on methotrexate treatment in rats with adjuvant arthritis","volume":"31","author":"Rovensk\u00fd","year":"2011","journal-title":"Rheumatol Int"},{"issue":"1","key":"10.1016\/j.joim.2022.07.002_b0535","doi-asserted-by":"crossref","first-page":"66","DOI":"10.4103\/0253-7613.106438","article-title":"Experimental evaluation of analgesic and anti-inflammatory potential of oyster mushroom Pleurotus florida","volume":"45","author":"Ganeshpurkar","year":"2013","journal-title":"Indian J Pharmacol"},{"key":"10.1016\/j.joim.2022.07.002_b0540","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/j.carbpol.2014.07.057","article-title":"Structural characterization and anti-inflammatory activity of a linear \u03b2-D-glucan isolated from Pleurotus sajor-caju","volume":"113","author":"Silveira","year":"2014","journal-title":"Carbohydr Polym"},{"key":"10.1016\/j.joim.2022.07.002_b0545","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.ijbiomac.2015.01.023","article-title":"Exopolysaccharide produced by Pleurotus sajor-caju: its chemical structure and anti-inflammatory activity","volume":"75","author":"Silveira","year":"2015","journal-title":"Int J Biol Macromol"},{"issue":"2","key":"10.1016\/j.joim.2022.07.002_b0550","doi-asserted-by":"crossref","first-page":"141","DOI":"10.4103\/0253-7613.178826","article-title":"Anti-inflammatory effect of aqueous extracts of spent Pleurotus ostreatus substrates in mouse ears treated with 12-O-tetradecanoylphorbol-13-acetate","volume":"48","author":"Rivero-P\u00e9rez","year":"2016","journal-title":"Indian J Pharmacol"},{"issue":"1","key":"10.1016\/j.joim.2022.07.002_b0555","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/s12906-016-1546-6","article-title":"Pleurotus giganteus (Berk. Karun & Hyde), the giant oyster mushroom inhibits NO production in LPS\/H2O2 stimulated RAW 264.7 cells via STAT3 and COX-2 pathways","volume":"17","author":"Baskaran","year":"2017","journal-title":"BMC Complement Altern Med"},{"issue":"6","key":"10.1016\/j.joim.2022.07.002_b0560","doi-asserted-by":"crossref","first-page":"2175","DOI":"10.1039\/C7FO00244K","article-title":"Isolation of a novel bioactive protein from an edible mushroom Pleurotus eryngii and its anti-inflammatory potential","volume":"8","author":"Yuan","year":"2017","journal-title":"Food Funct"},{"issue":"6","key":"10.1016\/j.joim.2022.07.002_b0565","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1080\/14786419.2014.952230","article-title":"Antihyperglycaemic mechanisms of an aceteoside polymer from rose flowers and a polysaccharide-protein complex from abalone mushroom","volume":"29","author":"Chen","year":"2015","journal-title":"Nat Prod Res"},{"key":"10.1016\/j.joim.2022.07.002_b0570","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.ijbiomac.2015.11.045","article-title":"Antidiabetic effect of polysaccharides from Pleurotus ostreatus in streptozotocin-induced diabetic rats","volume":"83","author":"Zhang","year":"2016","journal-title":"Int J Biol Macromol"},{"issue":"3","key":"10.1016\/j.joim.2022.07.002_b0575","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/mnfr.201700444","article-title":"Antidiabetic activity of ergosterol from Pleurotus ostreatus in KK-Ay mice with spontaneous type 2 diabetes mellitus","volume":"62","author":"Xiong","year":"2018","journal-title":"Mol Nutr Food Res"},{"issue":"3","key":"10.1016\/j.joim.2022.07.002_b0580","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1042\/BSR20110012","article-title":"Isolation and identification of a novel polysaccharide-peptide complex with antioxidant, anti-proliferative and hypoglycaemic activities from the abalone mushroom","volume":"32","author":"Li","year":"2012","journal-title":"Biosci Rep"},{"issue":"3","key":"10.1016\/j.joim.2022.07.002_b0585","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1615\/IntJMedMushr.v16.i3.10","article-title":"Antidiabetic potential of polysaccharides from the white oyster culinary-medicinal mushroom Pleurotus florida (higher Basidiomycetes)","volume":"16","author":"Ganeshpurkar","year":"2014","journal-title":"Int J Med Mushrooms"},{"issue":"4","key":"10.1016\/j.joim.2022.07.002_b0590","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1089\/jmf.2009.1130","article-title":"An extract of the Pleurotus ostreatus mushroom bolsters the glutathione redox system in various organs of aged rats","volume":"13","author":"Jayakumar","year":"2010","journal-title":"J Med Food"},{"issue":"1","key":"10.1016\/j.joim.2022.07.002_b0595","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1097\/FJC.0b013e3182567fef","article-title":"Endogenous glucocorticoids inhibit myocardial inflammation induced by lipopolysaccharide: involvement of regulation of histone deacetylation","volume":"60","author":"Zhang","year":"2012","journal-title":"J Cardiovasc Pharmacol"},{"issue":"5","key":"10.1016\/j.joim.2022.07.002_b0600","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1016\/j.fct.2012.02.013","article-title":"Antioxidant properties and phenolic profile of the most widely appreciated cultivated mushrooms: a comparative study between in vivo and in vitro samples","volume":"50","author":"Reis","year":"2012","journal-title":"Food Chem Toxicol"},{"issue":"1","key":"10.1016\/j.joim.2022.07.002_b0605","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/s00253-005-0043-5","article-title":"Antihyperglycemic effect of polysaccharide from fermented broth of Pleurotus citrinopileatus","volume":"70","author":"Hu","year":"2006","journal-title":"Appl Microbiol Biotechnol"},{"key":"10.1016\/j.joim.2022.07.002_b0610","unstructured":"Khatun S, Islam A, Guler P, Cakilcioglu U, Chatterjee NC. Hypoglycemic activity of a dietary mushroom Pleurotus florida on alloxan induced diabetic rats. Biol Divers Conserv 20013;6(2):91\u20136."},{"issue":"2","key":"10.1016\/j.joim.2022.07.002_b0615","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1093\/ecam\/nem010","article-title":"Interaction of aqueous extract of Pleurotus pulmonarius (Fr.) Quel-Champ. with glyburide in alloxan induced diabetic mice","volume":"5","author":"Badole","year":"2008","journal-title":"Evid Based Complement Altern Med"},{"issue":"5","key":"10.1016\/j.joim.2022.07.002_b0620","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1007\/s12250-014-3486-y","article-title":"Antiviral activity of Basidiomycete mycelia against influenza type A (serotype H1N1) and herpes simplex virus type 2 in cell culture","volume":"29","author":"Krupodorova","year":"2014","journal-title":"Virol Sin"},{"issue":"1","key":"10.1016\/j.joim.2022.07.002_b0625","doi-asserted-by":"crossref","first-page":"e12937","DOI":"10.1111\/sji.12937","article-title":"Can medicinal mushrooms have prophylactic or therapeutic effect against COVID-19 and its pneumonic superinfection and complicating inflammation?","volume":"93","author":"Hetland","year":"2021","journal-title":"Scand J Immunol"},{"key":"10.1016\/j.joim.2022.07.002_b0630","doi-asserted-by":"crossref","first-page":"8562309","DOI":"10.1155\/2020\/8562309","article-title":"Efficacy of pleuran (\u03b2-glucan from Pleurotus ostreatus) in the management of herpes simplex virus type 1 infection","volume":"2020","author":"Urbancikova","year":"2020","journal-title":"Evid Based Complement Alternat Med"},{"issue":"4","key":"10.1016\/j.joim.2022.07.002_b0635","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.3390\/nu13041333","article-title":"Immunomodulating effects of fungal \u03b2-glucans: from traditional use to medicine","volume":"13","author":"van Steenwijk","year":"2021","journal-title":"Nutrients"},{"issue":"2","key":"10.1016\/j.joim.2022.07.002_b0640","doi-asserted-by":"crossref","first-page":"172","DOI":"10.23736\/S1121-421X.20.02697-5","article-title":"Possible therapeutic role of a highly standardized mixture of active compounds derived from cultured Lentinula edodes mycelia (AHCC) in patients infected with 2019 novel coronavirus","volume":"66","author":"Di Pierro","year":"2020","journal-title":"Minerva Gastroenterol Dietol"},{"issue":"2","key":"10.1016\/j.joim.2022.07.002_b0645","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.jtcme.2020.12.002","article-title":"Mushroom-derived bioactive compounds potentially serve as the inhibitors of SARS-CoV-2 main protease: an in silico approach","volume":"11","author":"Rangsinth","year":"2021","journal-title":"J Tradit Complement Med"}],"container-title":["Journal of Integrative Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2095496422000759?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2095496422000759?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:53:27Z","timestamp":1761864807000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2095496422000759"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9]]},"references-count":129,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,9]]}},"alternative-id":["S2095496422000759"],"URL":"https:\/\/doi.org\/10.1016\/j.joim.2022.07.002","relation":{},"ISSN":["2095-4964"],"issn-type":[{"value":"2095-4964","type":"print"}],"subject":[],"published":{"date-parts":[[2022,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effects of bioactive compounds from Pleurotus mushrooms on COVID-19 risk factors associated with the cardiovascular system","name":"articletitle","label":"Article Title"},{"value":"Journal of Integrative Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joim.2022.07.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Shanghai Yueyang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}