{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T22:44:28Z","timestamp":1781736268391,"version":"3.54.5"},"reference-count":82,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100011332","name":"University of the Chinese Academy of Sciences","doi-asserted-by":"publisher","award":["2020PB0002"],"award-info":[{"award-number":["2020PB0002"]}],"id":[{"id":"10.13039\/501100011332","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002367","name":"Chinese Academy of Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002367","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Integrative Medicine"],"published-print":{"date-parts":[[2022,11]]},"DOI":"10.1016\/j.joim.2022.08.001","type":"journal-article","created":{"date-parts":[[2022,8,9]],"date-time":"2022-08-09T02:02:34Z","timestamp":1660010554000},"page":"488-496","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["Potential medicinal plants involved in inhibiting 3CLpro activity: A practical alternate approach to combating COVID-19"],"prefix":"10.1016","volume":"20","author":[{"given":"Fan","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-lan","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akash","family":"Tariq","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sehrish","family":"Sadia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeeshan","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordi","family":"Sardans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Aleem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riaz","family":"Ullah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rainer W.","family":"Bussmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10228","key":"10.1016\/j.joim.2022.08.001_b0005","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1016\/S0140-6736(20)30419-0","article-title":"A distinct name is needed for the new coronavirus","volume":"395","author":"Jiang","year":"2020","journal-title":"Lancet"},{"issue":"12","key":"10.1016\/j.joim.2022.08.001_b0010","doi-asserted-by":"crossref","first-page":"7035","DOI":"10.3390\/ijerph19127035","article-title":"Equilibrium of tiered healthcare resources during the COVID-19 pandemic in China: a case study of Taiyuan, Shanxi Province","volume":"19","author":"Wu","year":"2022","journal-title":"Int J Environ Res Public Health"},{"issue":"7798","key":"10.1016\/j.joim.2022.08.001_b0015","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1038\/s41586-020-2012-7","article-title":"A pneumonia outbreak associated with a new coronavirus of probable bat origin","volume":"579","author":"Zhou","year":"2020","journal-title":"Nature"},{"issue":"7898","key":"10.1016\/j.joim.2022.08.001_b0020","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1038\/s41586-021-04387-1","article-title":"Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization","volume":"602","author":"Cele","year":"2022","journal-title":"Nature"},{"issue":"6538","key":"10.1016\/j.joim.2022.08.001_b0025","doi-asserted-by":"crossref","DOI":"10.1126\/science.abg3055","article-title":"Estimated transmissibility and impact of SARS-CoV-2 lineage B.1.1.7 in England","volume":"372","author":"Davies","year":"2021","journal-title":"Science"},{"issue":"9","key":"10.1016\/j.joim.2022.08.001_b0030","doi-asserted-by":"crossref","first-page":"2348","DOI":"10.1016\/j.cell.2021.02.037","article-title":"Evidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine-induced sera","volume":"184","author":"Zhou","year":"2021","journal-title":"Cell"},{"issue":"1","key":"10.1016\/j.joim.2022.08.001_b0035","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1007\/s12038-021-00145-7","article-title":"SARS-CoV-2 genomics: an Indian perspective on sequencing viral variants","volume":"46","author":"Srivastava","year":"2021","journal-title":"J Biosci"},{"issue":"7902","key":"10.1016\/j.joim.2022.08.001_b0040","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1038\/s41586-022-04479-6","article-title":"SARS-CoV-2 omicron variant replication in human bronchus and lung ex vivo","volume":"603","author":"Hui","year":"2022","journal-title":"Nature"},{"issue":"7904","key":"10.1016\/j.joim.2022.08.001_b0045","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1038\/s41586-022-04482-x","article-title":"Pyrimidine inhibitors synergize with nucleoside analogues to block SARS-CoV-2","volume":"604","author":"Schultz","year":"2022","journal-title":"Nature"},{"issue":"12","key":"10.1016\/j.joim.2022.08.001_b0050","doi-asserted-by":"crossref","first-page":"3124","DOI":"10.1002\/ptr.6770","article-title":"Food as medicine: a possible preventive measure against coronavirus disease (COVID-19)","volume":"34","author":"Yang","year":"2020","journal-title":"Phytother Res"},{"issue":"9","key":"10.1016\/j.joim.2022.08.001_b0055","doi-asserted-by":"crossref","first-page":"2140","DOI":"10.1002\/ptr.6665","article-title":"Areca catechu\u2014from farm to food and biomedical applications","volume":"34","author":"Salehi","year":"2020","journal-title":"Phytother Res"},{"issue":"3","key":"10.1016\/j.joim.2022.08.001_b0060","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1142\/S0192415X20500378","article-title":"COVID-19: an update on the epidemiological, clinical, preventive and therapeutic evidence and guidelines of integrative Chinese-Western medicine for the management of 2019 novel coronavirus disease","volume":"48","author":"Chan","year":"2020","journal-title":"Am J Chin Med"},{"key":"10.1016\/j.joim.2022.08.001_b0065","doi-asserted-by":"crossref","first-page":"138277","DOI":"10.1016\/j.scitotenv.2020.138277","article-title":"COVID-19: a promising cure for the global panic","volume":"725","author":"Vellingiri","year":"2020","journal-title":"Sci Total Environ"},{"key":"10.1016\/j.joim.2022.08.001_b0070","doi-asserted-by":"crossref","first-page":"101165","DOI":"10.1016\/j.ctcp.2020.101165","article-title":"Traditional Chinese medicine treatment of COVID-19","volume":"39","author":"Xu","year":"2020","journal-title":"Compl Ther Clin Pract"},{"issue":"10","key":"10.1016\/j.joim.2022.08.001_b0075","doi-asserted-by":"crossref","first-page":"5086","DOI":"10.3390\/ijerph18105086","article-title":"Patients\u2019 behavior regarding dietary or herbal supplements before and during COVID-19 in Saudi Arabia","volume":"18","author":"Aldwihi","year":"2021","journal-title":"Int J Environ Res Publ Health"},{"key":"10.1016\/j.joim.2022.08.001_b0080","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.antiviral.2014.06.013","article-title":"Accessory proteins of SARS-CoV and other coronaviruses","volume":"109","author":"Liu","year":"2014","journal-title":"Antivir Res"},{"key":"10.1016\/j.joim.2022.08.001_b0085","doi-asserted-by":"crossref","first-page":"103936","DOI":"10.1016\/j.compbiomed.2020.103936","article-title":"In silico ADMET and molecular docking study on searching potential inhibitors from limnoids and triterpenoids for COVID-19","volume":"124","author":"Vardhan","year":"2020","journal-title":"Comput Biol Med"},{"key":"10.1016\/j.joim.2022.08.001_b0090","doi-asserted-by":"crossref","first-page":"105367","DOI":"10.1016\/j.compbiomed.2022.105367","article-title":"Computational studies on the interaction of SARS-CoV-2 omicron SGp RBD with human receptors ACE2, limonin and glycyrrhizic acid","volume":"144","author":"Vardhan","year":"2022","journal-title":"Comput Biol Med"},{"issue":"6","key":"10.1016\/j.joim.2022.08.001_b0095","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1097\/JCMA.0000000000000318","article-title":"Potential therapeutic agents against COVID-19: what we know so far","volume":"83","author":"Lu","year":"2020","journal-title":"J Chin Med Assoc"},{"issue":"4","key":"10.1016\/j.joim.2022.08.001_b0100","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.jpha.2020.03.009","article-title":"Structural basis of SARS-CoV-2 3CLpro and anti-COVID-19 drug discovery from medicinal plants","volume":"10","author":"Qamar","year":"2020","journal-title":"J Pharm Anal"},{"issue":"3","key":"10.1016\/j.joim.2022.08.001_b0105","first-page":"804","article-title":"Potential SARS-CoV-2 main protease inhibitors","volume":"26","author":"Banerjee","year":"2021","journal-title":"Drug Discov"},{"issue":"6","key":"10.1016\/j.joim.2022.08.001_b0110","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/j.immuni.2020.04.023","article-title":"Detection of SARS-CoV-2-specific humoral and cellular immunity in COVID-19 convalescent individuals","volume":"52","author":"Ni","year":"2020","journal-title":"Immunity"},{"issue":"8","key":"10.1016\/j.joim.2022.08.001_b0115","doi-asserted-by":"crossref","first-page":"1930","DOI":"10.1093\/cid\/ciaa461","article-title":"Antibody detection and dynamic characteristics in patients with COVID-19","volume":"71","author":"Xiang","year":"2020","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.joim.2022.08.001_b0120","doi-asserted-by":"crossref","first-page":"102199","DOI":"10.1016\/j.redox.2021.102199","article-title":"Oxidative stress transforms 3CLpro into an insoluble and more active form to promote SARS-CoV-2 replication","volume":"48","author":"Du","year":"2021","journal-title":"Redox Biol"},{"key":"10.1016\/j.joim.2022.08.001_b0125","article-title":"COVID-19: Pfizer\u2019s paxlovid is 89% effective in patients at risk of serious illness, company reports","volume":"375","author":"Mahase","year":"2021","journal-title":"BMJ"},{"issue":"1","key":"10.1016\/j.joim.2022.08.001_b0130","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1038\/s41598-022-05424-3","article-title":"Pro108Ser mutation of SARS-CoV-2 3CLpro reduces the enzyme activity and ameliorates the clinical severity of COVID-19","volume":"12","author":"Abe","year":"2022","journal-title":"Sci Rep"},{"issue":"1","key":"10.1016\/j.joim.2022.08.001_b0135","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1038\/s41467-022-28354-0","article-title":"The oral protease inhibitor (PF-07321332) protects Syrian hamsters against infection with SARS-CoV-2 variants of concern","volume":"13","author":"Abdelnabi","year":"2022","journal-title":"Nat Commun"},{"issue":"1\u20133","key":"10.1016\/j.joim.2022.08.001_b0140","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.febslet.2004.08.015","article-title":"Evaluation of metal-conjugated compounds as inhibitors of 3CL protease of SARS-CoV","volume":"574","author":"Hsu","year":"2004","journal-title":"FEBS Lett"},{"issue":"16","key":"10.1016\/j.joim.2022.08.001_b0145","doi-asserted-by":"crossref","first-page":"2600","DOI":"10.1002\/cbic.202100186","article-title":"Metal complexes as antiviral agents for SARS-CoV","volume":"22","author":"Karges","year":"2021","journal-title":"ChemBioChem"},{"issue":"19","key":"10.1016\/j.joim.2022.08.001_b0150","doi-asserted-by":"crossref","first-page":"10716","DOI":"10.1002\/anie.202016768","article-title":"ReI tricarbonyl complexes as coordinate covalent inhibitors for the SARS-CoV-2 main cysteine protease","volume":"60","author":"Karges","year":"2021","journal-title":"Angew Chem Int Ed Engl"},{"issue":"18","key":"10.1016\/j.joim.2022.08.001_b0155","doi-asserted-by":"crossref","first-page":"5602","DOI":"10.1016\/j.bmcl.2011.06.130","article-title":"Characteristic of alkylated chalcones from Angelica keiskei on influenza virus neuraminidase inhibition","volume":"21","author":"Park","year":"2011","journal-title":"Bioorg Med Chem Lett"},{"issue":"1","key":"10.1016\/j.joim.2022.08.001_b0160","doi-asserted-by":"crossref","first-page":"23","DOI":"10.3109\/14756366.2014.1003215","article-title":"Chalcones isolated from Angelica keiskei inhibit cysteine proteases of SARS-CoV","volume":"31","author":"Park","year":"2016","journal-title":"J Enzyme Inhib Med Chem"},{"issue":"2","key":"10.1016\/j.joim.2022.08.001_b0165","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1093\/ecam\/neh081","article-title":"Inhibition of SARS-CoV 3C-like protease activity by theaflavin-3,3\u2019-digallate (TF3)","volume":"2","author":"Chen","year":"2005","journal-title":"Evid Based Complement Alternat Med"},{"issue":"1","key":"10.1016\/j.joim.2022.08.001_b0170","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S2225-4110(16)30055-4","article-title":"Traditional Chinese medicine herbal extracts of Cibotium barometz, Gentiana scabra, Dioscorea batatas, Cassia tora, and Taxillus chinensis inhibit SARS-CoV replication","volume":"1","author":"Wen","year":"2011","journal-title":"J Trad Complem Med"},{"issue":"6","key":"10.1016\/j.joim.2022.08.001_b0175","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.5530\/pj.2020.12.174","article-title":"Phytotherapeutic evidence against coronaviruses and prospects for COVID-19","volume":"12","author":"Jamiu","year":"2020","journal-title":"Pharmacogn J"},{"issue":"17","key":"10.1016\/j.joim.2022.08.001_b0180","doi-asserted-by":"crossref","first-page":"4087","DOI":"10.1021\/jm070295s","article-title":"Specific plant terpenoids and lignoids possess potent antiviral activities against severe acute respiratory syndrome coronavirus","volume":"50","author":"Wen","year":"2007","journal-title":"J Med Chem"},{"issue":"13","key":"10.1016\/j.joim.2022.08.001_b0185","doi-asserted-by":"crossref","first-page":"3730","DOI":"10.1016\/j.bmc.2013.04.026","article-title":"Dieckol, a SARS-CoV 3CLpro inhibitor, isolated from edible brown algae Ecklonia cava","volume":"21","author":"Park","year":"2013","journal-title":"Bioorg Med Chem"},{"issue":"1","key":"10.1016\/j.joim.2022.08.001_b0190","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.jep.2008.03.018","article-title":"Immunomodulatory and anti-SARS activities of Houttuynia cordata","volume":"118","author":"Lau","year":"2008","journal-title":"J Ethnopharmacol"},{"issue":"1","key":"10.1016\/j.joim.2022.08.001_b0195","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.antiviral.2005.07.002","article-title":"Anti-SARS coronavirus 3C-like protease effects of Isatis indigotica root and plant-derived phenolic compounds","volume":"68","author":"Lin","year":"2005","journal-title":"Antiviral Res"},{"issue":"5","key":"10.1016\/j.joim.2022.08.001_b0200","first-page":"699","article-title":"A study on anti-SARS-CoV 3CL protein of flavonoids from Litchi chinensis Sonn core","volume":"24","author":"Gong","year":"2008","journal-title":"Zhongguo Yao Li Xue Tong Bao"},{"issue":"12","key":"10.1016\/j.joim.2022.08.001_b0205","doi-asserted-by":"crossref","first-page":"21854","DOI":"10.3390\/molecules201219806","article-title":"Comparative analysis of Amaryllidaceae alkaloids from three Lycoris species","volume":"20","author":"Tian","year":"2015","journal-title":"Molecules"},{"issue":"1","key":"10.1016\/j.joim.2022.08.001_b0210","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.antiviral.2005.02.007","article-title":"Identification of natural compounds with antiviral activities against SARS-associated coronavirus","volume":"67","author":"Li","year":"2005","journal-title":"Antiviral Res"},{"issue":"4","key":"10.1016\/j.joim.2022.08.001_b0215","first-page":"124","article-title":"Anti-SARS coronavirus 3C-like protease effects of Rheum palmatum L. extracts","volume":"3","author":"Luo","year":"2009","journal-title":"Biosci Trends"},{"issue":"19","key":"10.1016\/j.joim.2022.08.001_b0220","doi-asserted-by":"crossref","first-page":"5928","DOI":"10.1016\/j.bmc.2012.07.038","article-title":"Tanshinones as selective and slow-binding inhibitors for SARS-CoV cysteine proteases","volume":"20","author":"Park","year":"2012","journal-title":"Bioorg Med Chem"},{"issue":"22","key":"10.1016\/j.joim.2022.08.001_b0225","doi-asserted-by":"crossref","first-page":"7940","DOI":"10.1016\/j.bmc.2010.09.035","article-title":"Biflavonoids from Torreya nucifera displaying SARS-CoV 3CLpro inhibition","volume":"18","author":"Ryu","year":"2010","journal-title":"Bioorg Med Chem"},{"issue":"6","key":"10.1016\/j.joim.2022.08.001_b0230","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1016\/j.bmcl.2010.01.152","article-title":"SARS-CoV 3CLpro inhibitory effects of quinone-methide triterpenes from Tripterygium regelii","volume":"20","author":"Ryu","year":"2010","journal-title":"Bioorg Med Chem Lett"},{"issue":"2","key":"10.1016\/j.joim.2022.08.001_b0235","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0304-3835(03)00466-X","article-title":"Chalcones, coumarins, and flavanones from the exudate of Angelica keiskei and their chemopreventive effects","volume":"201","author":"Akihisa","year":"2003","journal-title":"Cancer Lett"},{"issue":"1","key":"10.1016\/j.joim.2022.08.001_b0240","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1021\/np058080d","article-title":"Chalcones and other compounds from the exudates of Angelica keiskei and their cancer chemopreventive effects","volume":"69","author":"Akihisa","year":"2006","journal-title":"J Nat Prod"},{"issue":"10","key":"10.1016\/j.joim.2022.08.001_b0245","doi-asserted-by":"crossref","first-page":"1878","DOI":"10.1248\/bpb.30.1878","article-title":"Isobavachalcone, a chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma","volume":"30","author":"Nishimura","year":"2007","journal-title":"Biol Pharm Bull"},{"issue":"1","key":"10.1016\/j.joim.2022.08.001_b0250","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1038\/sj.ejcn.1602489","article-title":"Black tea\u2014helpful or harmful? A review of the evidence","volume":"61","author":"Gardner","year":"2007","journal-title":"Eur J Clin Nutr"},{"issue":"2","key":"10.1016\/j.joim.2022.08.001_b0255","doi-asserted-by":"crossref","first-page":"474","DOI":"10.3390\/nu11020474","article-title":"A review of the role of green tea (Camellia sinensis) in antiphotoaging, stress resistance, neuroprotection, and autophagy","volume":"11","author":"Prasanth","year":"2019","journal-title":"Nutrients"},{"issue":"2","key":"10.1016\/j.joim.2022.08.001_b0260","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1080\/07315724.2006.10719518","article-title":"Beneficial effects of green tea\u2014a review","volume":"25","author":"Cabrera","year":"2006","journal-title":"J Am Coll Nutr"},{"issue":"7","key":"10.1016\/j.joim.2022.08.001_b0265","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1080\/10408398.2012.678949","article-title":"Tea and its consumption: benefits and risks","volume":"55","author":"Hayat","year":"2015","journal-title":"Crit Rev Food Sci Nutr"},{"issue":"8","key":"10.1016\/j.joim.2022.08.001_b0270","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.3390\/molecules22081337","article-title":"A review of the antiviral role of green tea catechins","volume":"22","author":"Xu","year":"2017","journal-title":"Molecules"},{"issue":"6","key":"10.1016\/j.joim.2022.08.001_b0275","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1248\/bpb.27.863","article-title":"Antibacterial and antifungal effects of essential oils from coniferous trees","volume":"27","author":"Hong","year":"2004","journal-title":"Biol Pharm Bull"},{"issue":"2","key":"10.1016\/j.joim.2022.08.001_b0280","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.fitote.2006.09.026","article-title":"Chemical composition and antimicrobial activity of Chamaecyparis obtusa leaf essential oil","volume":"78","author":"Yang","year":"2007","journal-title":"Fitoterapia"},{"issue":"1","key":"10.1016\/j.joim.2022.08.001_b0285","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.fitote.2009.06.016","article-title":"The essential oils of Chamaecyparis obtusa promote hair growth through the induction of vascular endothelial growth factor gene","volume":"81","author":"Lee","year":"2010","journal-title":"Fitoterapia"},{"key":"10.1016\/j.joim.2022.08.001_b0290","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.antiviral.2006.01.011","article-title":"Yatein from Chamaecyparis obtusa suppresses herpes simplex virus type 1 replication in HeLa cells by interrupting the immediate-early gene expression","volume":"70","author":"Kuo","year":"2006","journal-title":"Antiviral Res"},{"issue":"10","key":"10.1016\/j.joim.2022.08.001_b0295","doi-asserted-by":"crossref","first-page":"4439","DOI":"10.1021\/jf9003913","article-title":"Inhibitory effects and molecular mechanism of dieckol isolated from marine brown alga on COX-2 and iNOS in microglial cells","volume":"57","author":"Jung","year":"2009","journal-title":"J Agric Food Chem"},{"issue":"10","key":"10.1016\/j.joim.2022.08.001_b0300","first-page":"e5003","article-title":"Scientific opinion on the safety of Ecklonia cava phlorotannins as a novel food pursuant to Regulation (EC) No 258\/97","volume":"15","author":"Turck","year":"2017","journal-title":"EFSA J"},{"issue":"1\u20133","key":"10.1016\/j.joim.2022.08.001_b0305","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.ejphar.2010.09.032","article-title":"Fucoxanthin inhibits the inflammatory response by suppressing the activation of NF-\u03baB and MAPKs in lipopolysaccharide-induced RAW 264.7 macrophages","volume":"649","author":"Kim","year":"2010","journal-title":"Eur J Pharmacol"},{"issue":"9","key":"10.1016\/j.joim.2022.08.001_b0310","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1002\/jsfa.3623","article-title":"\u03b1-Glucosidase and \u03b1-amylase inhibitory activities of phloroglucinal derivatives from edible marine brown alga, Ecklonia cava","volume":"89","author":"Lee","year":"2009","journal-title":"J Sci Food Agric"},{"issue":"4","key":"10.1016\/j.joim.2022.08.001_b0315","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1089\/fpd.2009.0434","article-title":"Antibacterial activity of Ecklonia cava against methicillin-resistant Staphylococcus aureus and Salmonella spp","volume":"7","author":"Choi","year":"2010","journal-title":"Foodborn Pathog Dis"},{"key":"10.1016\/j.joim.2022.08.001_b0320","doi-asserted-by":"crossref","unstructured":"Bais S, Gill NS, Rana N, Shandil, S. A phytopharmacological review on a medicinal plant: Juniperus communis. Int Sch Res Notices 2014;2014:634723.","DOI":"10.1155\/2014\/634723"},{"issue":"1\u20132","key":"10.1016\/j.joim.2022.08.001_b0325","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.jep.2005.09.012","article-title":"Anti-inflammatory effect of Houttuynia cordata injection","volume":"104","author":"Lu","year":"2006","journal-title":"J Ethnopharmacol"},{"issue":"3","key":"10.1016\/j.joim.2022.08.001_b0330","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1142\/S0192415X03001090","article-title":"Anti-herpes simplex virus activity of Bidens pilosa and Houttuynia cordata","volume":"31","author":"Chiang","year":"2003","journal-title":"Am J Chin Med"},{"issue":"6","key":"10.1016\/j.joim.2022.08.001_b0335","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1007\/BF02975156","article-title":"Cytotoxic alkaloids from Houttuynia cordata","volume":"24","author":"Kim","year":"2001","journal-title":"Arch Pharm Res"},{"key":"10.1016\/j.joim.2022.08.001_b0340","doi-asserted-by":"crossref","first-page":"714694","DOI":"10.3389\/fphar.2021.714694","article-title":"Houttuynia cordata Thunb: an ethnopharmacological review","volume":"12","author":"Wu","year":"2021","journal-title":"Front Pharmacol"},{"issue":"6","key":"10.1016\/j.joim.2022.08.001_b0345","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1002\/(SICI)1098-1128(199811)18:6<375::AID-MED2>3.0.CO;2-8","article-title":"Recent advances on bioactive natural products from Chinese medicinal plants","volume":"18","author":"Qin","year":"1998","journal-title":"Med Res Rev"},{"issue":"4","key":"10.1016\/j.joim.2022.08.001_b0350","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1021\/bp0300624","article-title":"Quantitative analysis of indigo and indigo precursors in leaves of Isatis spp. and Polygonum tinctorium","volume":"20","author":"Gilbert","year":"2004","journal-title":"Biotechnol Prog"},{"issue":"18","key":"10.1016\/j.joim.2022.08.001_b0355","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1097\/01.aids.0000194805.74293.11","article-title":"Indirubin-3-monoxime, a derivative of a Chinese antileukemia medicine, inhibits P-TEFb function and HIV-1 replication","volume":"19","author":"Heredia","year":"2005","journal-title":"AIDS"},{"key":"10.1016\/j.joim.2022.08.001_b0360","doi-asserted-by":"crossref","first-page":"3223","DOI":"10.4028\/www.scientific.net\/AMM.411-414.3223","article-title":"The research on the medicinal value of Amaryllidaceae plants","volume":"411\u2013414","author":"Ji","year":"2013","journal-title":"Appl Mech Mater"},{"issue":"12","key":"10.1016\/j.joim.2022.08.001_b0365","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.00023-19","article-title":"High throughput screening and identification of potent broad-spectrum inhibitors of coronaviruses","volume":"93","author":"Shen","year":"2019","journal-title":"J Virol"},{"key":"10.1016\/j.joim.2022.08.001_b0370","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1186\/1743-422X-8-483","article-title":"Lycorine reduces mortality of human entero virus 71-infected mice by inhibiting virus replication","volume":"8","author":"Liu","year":"2011","journal-title":"Virol J"},{"issue":"12","key":"10.1016\/j.joim.2022.08.001_b0375","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1177\/0091270005282630","article-title":"Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use","volume":"45","author":"Zhou","year":"2005","journal-title":"J Clin Pharmacol"},{"issue":"25","key":"10.1016\/j.joim.2022.08.001_b0380","first-page":"2813","article-title":"Salvia miltiorrhiza: chemical and pharmacological review of a medicinal plant","volume":"4","author":"Wang","year":"2010","journal-title":"J Med Plants Res"},{"issue":"1","key":"10.1016\/j.joim.2022.08.001_b0385","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0166-3542(02)00011-6","article-title":"Isolation of two highly potent and non-toxic inhibitors of human immuno-deficiency virus type 1 (HIV-1) integrase from Salvia miltiorrhiza","volume":"55","author":"Abd-Elazem","year":"2002","journal-title":"Antiviral Res"},{"issue":"1","key":"10.1016\/j.joim.2022.08.001_b0390","doi-asserted-by":"crossref","first-page":"21","DOI":"10.12729\/jbtr.2018.19.1.021","article-title":"The anti-influenza effect of a water soluble herbal extract from Salvia miltiorrhiza (Danshen) in vivo","volume":"19","author":"Lee","year":"2018","journal-title":"J Biomed Trans Res"},{"issue":"01","key":"10.1016\/j.joim.2022.08.001_b0395","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1142\/S0192415X07004709","article-title":"Antiviral effects of Salvia miltiorrhiza (Danshen) against enterovirus 71","volume":"35","author":"Wu","year":"2007","journal-title":"Am J Chin Med"},{"issue":"20","key":"10.1016\/j.joim.2022.08.001_b0400","doi-asserted-by":"crossref","first-page":"8612","DOI":"10.1002\/ece3.3344","article-title":"Phylogeographic and phylogenetic analysis for Tripterygium species delimitation","volume":"7","author":"Ma","year":"2017","journal-title":"Ecol Evol"},{"issue":"3","key":"10.1016\/j.joim.2022.08.001_b0405","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.intimp.2011.01.012","article-title":"Triptolide and its expanding multiple pharmacological functions","volume":"11","author":"Liu","year":"2011","journal-title":"Int Immunopharmacol"},{"issue":"4","key":"10.1016\/j.joim.2022.08.001_b0410","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1093\/jac\/37.4.759","article-title":"Characterization of antiviral activity of a sesquiterpene, triptofordin C-2","volume":"37","author":"Hayashi","year":"1996","journal-title":"J Antimicrob Chemother"}],"container-title":["Journal of Integrative Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2095496422000899?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2095496422000899?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:53:15Z","timestamp":1761864795000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2095496422000899"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":82,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["S2095496422000899"],"URL":"https:\/\/doi.org\/10.1016\/j.joim.2022.08.001","relation":{},"ISSN":["2095-4964"],"issn-type":[{"value":"2095-4964","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Potential medicinal plants involved in inhibiting 3CLpro activity: A practical alternate approach to combating COVID-19","name":"articletitle","label":"Article Title"},{"value":"Journal of Integrative Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joim.2022.08.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Shanghai Yueyang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}