{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T21:54:46Z","timestamp":1781646886163,"version":"3.54.5"},"reference-count":40,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["HI16C0887"],"award-info":[{"award-number":["HI16C0887"]}],"id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Integrative Medicine"],"published-print":{"date-parts":[[2023,11]]},"DOI":"10.1016\/j.joim.2023.10.004","type":"journal-article","created":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T22:39:49Z","timestamp":1698878389000},"page":"537-542","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Electroacupuncture for abdominal pain relief in patients with acute pancreatitis: A three-arm randomized controlled trial"],"prefix":"10.1016","volume":"21","author":[{"given":"Dong","family":"Kee Jang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Kyu Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chan","family":"Yung Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung","family":"Ho Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ha","family":"Ra Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeon","family":"Sun Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jong","family":"Hwa Yoon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwang","family":"Ro Joo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Kyu Chae","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Hyeon Baek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byung-Kwan","family":"Seo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang","family":"Hyub Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiyeon","family":"Lim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.joim.2023.10.004_b0005","doi-asserted-by":"crossref","unstructured":"Peery AF, Dellon ES, Lund J, Crockett SD, McGowan CE, Bulsiewicz WJ, et al. Burden of gastrointestinal disease in the United States: 2012 update. Gastroenterology 2012;143(5):1179\u201387. e3.","DOI":"10.1053\/j.gastro.2012.08.002"},{"issue":"4","key":"10.1016\/j.joim.2023.10.004_b0010","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1097\/MPA.0000000000000783","article-title":"The changing epidemiology of acute pancreatitis hospitalizations: a decade of trends and the impact of chronic pancreatitis","volume":"46","author":"Krishna","year":"2017","journal-title":"Pancreas"},{"issue":"4","key":"10.1016\/j.joim.2023.10.004_b0015","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1097\/01.mpa.0000236733.31617.52","article-title":"Trends in the epidemiology of the first attack of acute pancreatitis: a systematic review","volume":"33","author":"Yadav","year":"2006","journal-title":"Pancreas"},{"issue":"6","key":"10.1016\/j.joim.2023.10.004_b0020","doi-asserted-by":"crossref","first-page":"787","DOI":"10.3390\/medicina58060787","article-title":"Predicting severity of acute pancreatitis","volume":"58","author":"Lee","year":"2022","journal-title":"Medicina (Kaunas)"},{"issue":"8","key":"10.1016\/j.joim.2023.10.004_b0025","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1097\/MPA.0000000000000189","article-title":"Quality of life after acute pancreatitis: a systematic review and meta-analysis","volume":"43","author":"Pendharkar","year":"2014","journal-title":"Pancreas"},{"issue":"4","key":"10.1016\/j.joim.2023.10.004_b0030","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1053\/j.gastro.2018.01.032","article-title":"American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis","volume":"154","author":"Crockett","year":"2018","journal-title":"Gastroenterology"},{"issue":"7","key":"10.1016\/j.joim.2023.10.004_b0035","article-title":"Opioids for acute pancreatitis pain","author":"Basurto Ona","year":"2013","journal-title":"Cochrane Database Syst Rev"},{"issue":"2","key":"10.1016\/j.joim.2023.10.004_b0040","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1097\/MPA.0b013e318224056f","article-title":"Pain and opioid use in chronic pancreatitis","volume":"41","author":"Nusrat","year":"2012","journal-title":"Pancreas"},{"issue":"42","key":"10.1016\/j.joim.2023.10.004_b0045","doi-asserted-by":"crossref","first-page":"7302","DOI":"10.3748\/wjg.v19.i42.7302","article-title":"Pharmacological challenges in chronic pancreatitis","volume":"19","author":"Olesen","year":"2013","journal-title":"World J Gastroenterol"},{"issue":"50","key":"10.1016\/j.joim.2023.10.004_b0050","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.15585\/mmwr.mm6450a3","article-title":"Increases in drug and opioid overdose deaths\u2014United States, 2000\u20132014","volume":"64","author":"Rudd","year":"2016","journal-title":"MMWR Morb Mortal Wkly Rep"},{"issue":"5152","key":"10.1016\/j.joim.2023.10.004_b0055","first-page":"1419","article-title":"Drug and opioid-involved overdose deaths\u2014United States, 2013\u20132017","volume":"67","author":"Scholl","year":"2019","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"10.1016\/j.joim.2023.10.004_b0060","doi-asserted-by":"crossref","unstructured":"Ciesielski T, Iyengar R, Bothra A, Tomala D, Cislo G, Gage BF. A tool to assess risk of de novo opioid abuse or dependence. Am J Med 2016;129(7):699\u2013705.e4.","DOI":"10.1016\/j.amjmed.2016.02.014"},{"issue":"2","key":"10.1016\/j.joim.2023.10.004_b0065","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1097\/ALN.0000000000000101","article-title":"Mechanisms of acupuncture-electroacupuncture on persistent pain","volume":"120","author":"Zhang","year":"2014","journal-title":"Anesthesiology"},{"issue":"3","key":"10.1016\/j.joim.2023.10.004_b0070","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/0306-9877(95)90117-5","article-title":"Acupuncture\u2014from empiricism to science: functional background to acupuncture effects in pain and disease","volume":"45","author":"Andersson","year":"1995","journal-title":"Med Hypotheses"},{"key":"10.1016\/j.joim.2023.10.004_b0075","doi-asserted-by":"crossref","unstructured":"Lee A, Chan SKC, Fan LT. Stimulation of the wrist acupuncture point P6 for preventing postoperative nausea and vomiting. Cochrane Database Syst Rev 2009;(2):CD003281.","DOI":"10.1002\/14651858.CD003281.pub3"},{"issue":"5","key":"10.1016\/j.joim.2023.10.004_b0080","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1007\/s00535-006-1773-6","article-title":"Acupuncture for functional gastrointestinal disorders","volume":"41","author":"Takahashi","year":"2006","journal-title":"J Gastroenterol"},{"issue":"8","key":"10.1016\/j.joim.2023.10.004_b0085","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1111\/j.1365-2036.2004.02196.x","article-title":"Review article: therapeutic roles of acupuncture in functional gastrointestinal disorders","volume":"20","author":"Ouyang","year":"2004","journal-title":"Aliment Pharmacol Ther"},{"key":"10.1016\/j.joim.2023.10.004_b0090","doi-asserted-by":"crossref","unstructured":"Ng SSM, Leung WW, Mak TWC, Hon SSF, Li JCM, Wong CYN, et al. Electroacupuncture reduces duration of postoperative ileus after laparoscopic surgery for colorectal cancer. Gastroenterology 2013;144(2):307\u201313.e1.","DOI":"10.1053\/j.gastro.2012.10.050"},{"issue":"2","key":"10.1016\/j.joim.2023.10.004_b0095","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1136\/acupmed-2014-010646","article-title":"Effect of electroacupuncture on the inflammatory response in patients with acute pancreatitis: an exploratory study","volume":"33","author":"Zhu","year":"2015","journal-title":"Acupunct Med"},{"issue":"2","key":"10.1016\/j.joim.2023.10.004_b0100","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1097\/MPA.0000000000000749","article-title":"Acupuncture for pain in chronic pancreatitis: A single-blinded randomized crossover trial","volume":"46","author":"Juel","year":"2017","journal-title":"Pancreas"},{"issue":"1","key":"10.1016\/j.joim.2023.10.004_b0105","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1186\/s13063-018-2644-1","article-title":"Electroacupuncture for abdominal pain relief in patients with acute pancreatitis: study protocol for a randomized controlled trial","volume":"19","author":"Jang","year":"2018","journal-title":"Trials"},{"key":"10.1016\/j.joim.2023.10.004_b0110","doi-asserted-by":"crossref","unstructured":"World Medical Association. World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA 2013;310(20):2191\u20134.","DOI":"10.1001\/jama.2013.281053"},{"key":"10.1016\/j.joim.2023.10.004_b0115","doi-asserted-by":"crossref","unstructured":"Working Group IAPAPAAPG. IAP\/APA evidence-based guidelines for the management of acute pancreatitis. Pancreatology 2013;13(4 Suppl 2):e1\u201315.","DOI":"10.1016\/j.pan.2013.07.063"},{"issue":"10","key":"10.1016\/j.joim.2023.10.004_b0120","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1097\/00003246-199510000-00007","article-title":"Multiple organ dysfunction score: a reliable descriptor of a complex clinical outcome","volume":"23","author":"Marshall","year":"1995","journal-title":"Crit Care Med"},{"issue":"1","key":"10.1016\/j.joim.2023.10.004_b0125","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1136\/gutjnl-2012-302779","article-title":"Classification of acute pancreatitis\u20142012: revision of the Atlanta classification and definitions by international consensus","volume":"62","author":"Banks","year":"2013","journal-title":"Gut"},{"key":"10.1016\/j.joim.2023.10.004_b0130","unstructured":"Schorn S, Ceyhan GO, Tieftrunk E, Friess H, Demir IE. Pain management in acute pancreatitis. Pancreapedia: Exocrine Pancreas Knowledge Base. (2015-05-30)[2022-02-01]. https:\/\/www.pancreapedia.org\/node\/9004."},{"issue":"1","key":"10.1016\/j.joim.2023.10.004_b0135","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1089\/acm.1999.5.27","article-title":"Acupuncture for gastrointestinal and hepatobiliary disorders","volume":"5","author":"Diehl","year":"1999","journal-title":"J Altern Complement Med"},{"issue":"10","key":"10.1016\/j.joim.2023.10.004_b0140","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.3109\/00365528509089285","article-title":"Acupuncture and transcutaneous electric nerve stimulation in the treatment of pain associated with chronic pancreatitis","volume":"20","author":"Ballegaard","year":"1985","journal-title":"A randomized study Scand J Gastroenterol"},{"issue":"6","key":"10.1016\/j.joim.2023.10.004_b0145","first-page":"421","article-title":"Electroacupuncture for treatment of acute pancreatitis and its effect on the intestinal permeability of the patient","volume":"27","author":"Wang","year":"2007","journal-title":"Zhongguo Zhen Jiu"},{"key":"10.1016\/j.joim.2023.10.004_b0150","unstructured":"Society KAMM. Acupuncture Medicine. Seoul: Hanmi Medical Publishing Co.; 2016: 240\u20134, 688."},{"issue":"22","key":"10.1016\/j.joim.2023.10.004_b0155","doi-asserted-by":"crossref","first-page":"4120","DOI":"10.1200\/JCO.2003.09.011","article-title":"Analgesic effect of auricular acupuncture for cancer pain: a randomized, blinded, controlled trial","volume":"21","author":"Alimi","year":"2003","journal-title":"J Clin Oncol"},{"issue":"3","key":"10.1016\/j.joim.2023.10.004_b0160","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.pan.2013.02.003","article-title":"Parenteral analgesics for pain relief in acute pancreatitis: a systematic review","volume":"13","author":"Meng","year":"2013","journal-title":"Pancreatology"},{"issue":"1","key":"10.1016\/j.joim.2023.10.004_b0165","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1023\/A:1021730314068","article-title":"Neural mechanism of acupuncture-induced gastric relaxations in rats","volume":"48","author":"Tada","year":"2003","journal-title":"Dig Dis Sci"},{"issue":"3","key":"10.1016\/j.joim.2023.10.004_b0170","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1089\/acu.2019.1339","article-title":"The science of auricular microsystem acupuncture: amygdala function in psychiatric, neuromusculoskeletal, and functional disorders","volume":"31","author":"Liebell","year":"2019","journal-title":"Med Acupunct"},{"key":"10.1016\/j.joim.2023.10.004_b0175","doi-asserted-by":"crossref","unstructured":"Zeliadt SB, Thomas ER, Olson J, Coggeshall S, Giannitrapani K, Ackland PE, et al. Patient feedback on the effectiveness of auricular acupuncture on pain in routine clinical care: the experience of 11,406 veterans. Med Care 2020;58 Suppl 2 9S(2 9 Suppl):S101\u20137.","DOI":"10.1097\/MLR.0000000000001368"},{"issue":"6","key":"10.1016\/j.joim.2023.10.004_b0180","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/j.ajem.2018.02.038","article-title":"Battlefield acupuncture to treat low back pain in the emergency department","volume":"36","author":"Fox","year":"2018","journal-title":"Am J Emerg Med"},{"issue":"3","key":"10.1016\/j.joim.2023.10.004_b0185","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1093\/pm\/pnw215","article-title":"Ear acupuncture for immediate pain relief\u2014a systematic review and meta-analysis of randomized controlled trials","volume":"18","author":"Murakami","year":"2017","journal-title":"Pain Med"},{"key":"10.1016\/j.joim.2023.10.004_b0190","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.heares.2017.12.003","article-title":"Transauricular vagus nerve stimulation at auricular acupoints Kindey (CO10), Yidan (CO11), Liver (CO12) and Shenmen (TF4) can induce auditory and limbic cortices activation measured by fMRI","volume":"359","author":"Peng","year":"2018","journal-title":"Hear Res"},{"issue":"6","key":"10.1016\/j.joim.2023.10.004_b0195","first-page":"514","article-title":"Is the WHO analgesic ladder still valid? Twenty-four years of experience","volume":"56","author":"Vargas-Schaffer","year":"2010","journal-title":"Can Fam Physician"},{"issue":"5","key":"10.1016\/j.joim.2023.10.004_b0200","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1055\/a-0588-5365","article-title":"Endoscopic management of acute necrotizing pancreatitis: European Society of Gastrointestinal Endoscopy (ESGE) evidence-based multidisciplinary guidelines","volume":"50","author":"Arvanitakis","year":"2018","journal-title":"Endoscopy"}],"container-title":["Journal of Integrative Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S209549642300081X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S209549642300081X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:54:57Z","timestamp":1761864897000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S209549642300081X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":40,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,11]]}},"alternative-id":["S209549642300081X"],"URL":"https:\/\/doi.org\/10.1016\/j.joim.2023.10.004","relation":{},"ISSN":["2095-4964"],"issn-type":[{"value":"2095-4964","type":"print"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Electroacupuncture for abdominal pain relief in patients with acute pancreatitis: A three-arm randomized controlled trial","name":"articletitle","label":"Article Title"},{"value":"Journal of Integrative Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joim.2023.10.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Shanghai Yueyang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine.","name":"copyright","label":"Copyright"}]}}