{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T05:16:41Z","timestamp":1783228601384,"version":"3.54.6"},"reference-count":139,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T00:00:00Z","timestamp":1776816000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003819","name":"Natural Science Foundation of Hubei Province","doi-asserted-by":"publisher","award":["2024AFD251"],"award-info":[{"award-number":["2024AFD251"]}],"id":[{"id":"10.13039\/501100003819","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Integrative Medicine"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.joim.2026.04.002","type":"journal-article","created":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T15:54:30Z","timestamp":1775231670000},"page":"481-492","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Current state and future prospects of acupuncture for insomnia: From central mechanisms to peripheral effects"],"prefix":"10.1016","volume":"24","author":[{"given":"Si-yi","family":"Zhai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu-rui","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-yu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.joim.2026.04.002_b0005","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.chest.2017.01.026","article-title":"Insomnia and risk of cardiovascular disease","volume":"152","author":"Javaheri","year":"2017","journal-title":"Chest"},{"issue":"1\u20133","key":"10.1016\/j.joim.2026.04.002_b0010","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.jad.2011.01.011","article-title":"Insomnia as a predictor of depression: a meta-analytic evaluation of longitudinal epidemiological studies","volume":"135","author":"Baglioni","year":"2011","journal-title":"J Affect Disord"},{"issue":"Suppl 2","key":"10.1016\/j.joim.2026.04.002_b0015","doi-asserted-by":"crossref","first-page":"S204","DOI":"10.1542\/peds.2019-2056I","article-title":"Sleep disorders in adolescents","volume":"145","author":"Kansagra","year":"2020","journal-title":"Pediatrics"},{"issue":"2","key":"10.1016\/j.joim.2026.04.002_b0020","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0170772","article-title":"The prevalence of insomnia in the general population in China: a meta-analysis","volume":"12","author":"Cao","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.joim.2026.04.002_b0025","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1016\/j.bbi.2020.07.037","article-title":"Anxiety and depression in COVID-19 survivors: role of inflammatory and clinical predictors","volume":"89","author":"Mazza","year":"2020","journal-title":"Brain Behav Immun"},{"issue":"8","key":"10.1016\/j.joim.2026.04.002_b0030","doi-asserted-by":"crossref","first-page":"3214","DOI":"10.1038\/s41380-022-01638-z","article-title":"A systematic review and meta-analysis on prevalence of and risk factors associated with depression, anxiety and insomnia in infectious diseases, including COVID-19: a call to action","volume":"27","author":"Yuan","year":"2022","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.joim.2026.04.002_b0035","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.jad.2020.08.001","article-title":"Impact of COVID-19 pandemic on mental health in the general population: a systematic review","volume":"277","author":"Xiong","year":"2020","journal-title":"J Affect Disord"},{"issue":"1","key":"10.1016\/j.joim.2026.04.002_b0040","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1007\/s13311-021-01029-2","article-title":"Non-pharmacological approaches for management of insomnia","volume":"18","author":"Chan","year":"2021","journal-title":"Neurotherapeutics"},{"issue":"1","key":"10.1016\/j.joim.2026.04.002_b0045","first-page":"24927","article-title":"Zolpidem: efficacy and side effects for insomnia","volume":"9","author":"Edinoff","year":"2021","journal-title":"Health Psychol Res"},{"issue":"2","key":"10.1016\/j.joim.2026.04.002_b0050","first-page":"154","article-title":"Treatment of chronic insomnia in adults","volume":"109","author":"Matheson","year":"2024","journal-title":"Am Fam Physician"},{"issue":"3","key":"10.1016\/j.joim.2026.04.002_b0055","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1002\/wps.20567","article-title":"Management of common adverse effects of antipsychotic medications","volume":"17","author":"Stroup","year":"2018","journal-title":"World Psychiatry"},{"issue":"2","key":"10.1016\/j.joim.2026.04.002_b0060","doi-asserted-by":"crossref","first-page":"255","DOI":"10.5664\/jcsm.8986","article-title":"Behavioral and psychological treatments for chronic insomnia disorder in adults: an American Academy of sleep medicine clinical practice guideline","volume":"17","author":"Edinger","year":"2021","journal-title":"J Clin Sleep Med"},{"issue":"1","key":"10.1016\/j.joim.2026.04.002_b0065","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1007\/s41782-022-00197-1","article-title":"Management of chronic insomnia using cognitive behavior therapy for insomnia (CBT-I) during COVID-19 pandemic: does one shoe fit all?","volume":"6","author":"Pal","year":"2022","journal-title":"Sleep Vigil"},{"issue":"3","key":"10.1016\/j.joim.2026.04.002_b0070","doi-asserted-by":"crossref","first-page":"e6327","DOI":"10.1002\/pon.6327","article-title":"A retrospective cost-effectiveness analysis of different cognitive-behavioral therapy for insomnia intervention delivery approaches in adult cancer survivors","volume":"33","author":"Pilehvari","year":"2024","journal-title":"Psychooncology"},{"issue":"52","key":"10.1016\/j.joim.2026.04.002_b0075","doi-asserted-by":"crossref","first-page":"e9471","DOI":"10.1097\/MD.0000000000009471","article-title":"Acupuncture as a primary and independent treatment for a patient with chronic insomnia: one-year follow-up case report","volume":"96","author":"Zhang","year":"2017","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.joim.2026.04.002_b0080","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/319734","article-title":"Characterization of Deqi sensation and acupuncture effect","volume":"2013","author":"Yang","year":"2013","journal-title":"Evid Based Complement Alternat Med"},{"key":"10.1016\/j.joim.2026.04.002_b0085","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2022.1038945","article-title":"The autonomic nervous system: a potential link to the efficacy of acupuncture","volume":"16","author":"Li","year":"2022","journal-title":"Front Neurosci"},{"key":"10.1016\/j.joim.2026.04.002_b0090","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.ctim.2018.12.020","article-title":"Acupuncture for treatment of insomnia: an overview of systematic reviews","volume":"42","author":"He","year":"2019","journal-title":"Complement Ther Med"},{"issue":"9","key":"10.1016\/j.joim.2026.04.002_b0095","article-title":"Acupuncture for insomnia","volume":"2012","author":"Cheuk","year":"2012","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.joim.2026.04.002_b0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.smrv.2023.101892","article-title":"Acupuncture for primary insomnia: effectiveness, safety, mechanisms and recommendations for clinical practice","volume":"74","author":"Zhao","year":"2024","journal-title":"Sleep Med Rev"},{"issue":"22","key":"10.1016\/j.joim.2026.04.002_b0105","doi-asserted-by":"crossref","first-page":"4075","DOI":"10.1523\/JNEUROSCI.1913-22.2023","article-title":"Structure and function of neuronal circuits linking ventrolateral preoptic nucleus and lateral hypothalamic area","volume":"43","author":"Prokofeva","year":"2023","journal-title":"J Neurosci"},{"key":"10.1016\/j.joim.2026.04.002_b0110","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2023.1122803","article-title":"Neural pathways from hypothalamic orexin neurons to the ventrolateral preoptic area mediate sleep impairments induced by conditioned fear","volume":"17","author":"Ma","year":"2023","journal-title":"Front Neurosci"},{"issue":"14","key":"10.1016\/j.joim.2026.04.002_b0115","doi-asserted-by":"crossref","first-page":"2140","DOI":"10.3390\/cells11142140","article-title":"Activation of the ventrolateral preoptic neurons projecting to the perifornical-hypothalamic area promotes sleep: DREADD activation in wild-type rats","volume":"11","author":"Kostin","year":"2022","journal-title":"Cells"},{"issue":"1","key":"10.1016\/j.joim.2026.04.002_b0120","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.cub.2023.11.035","article-title":"Regulation of stress-induced sleep fragmentation by preoptic glutamatergic neurons","volume":"34","author":"Smith","year":"2024","journal-title":"Curr Biol"},{"issue":"16","key":"10.1016\/j.joim.2026.04.002_b0125","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.1016\/j.cub.2016.05.078","article-title":"A novel population of wake-promoting GABAergic neurons in the ventral lateral hypothalamus","volume":"26","author":"Venner","year":"2016","journal-title":"Curr Biol"},{"issue":"5","key":"10.1016\/j.joim.2026.04.002_b0130","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/j.cub.2019.12.063","article-title":"Activation of preoptic GABAergic or glutamatergic neurons modulates sleep-wake architecture, but not anesthetic state transitions","volume":"30","author":"Vanini","year":"2020","journal-title":"Curr Biol"},{"issue":"24","key":"10.1016\/j.joim.2026.04.002_b0135","doi-asserted-by":"crossref","first-page":"4155","DOI":"10.1016\/j.cub.2019.10.026","article-title":"An inhibitory lateral hypothalamic-preoptic circuit mediates rapid arousals from sleep","volume":"29","author":"Venner","year":"2019","journal-title":"Curr Biol"},{"issue":"37","key":"10.1016\/j.joim.2026.04.002_b0140","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abc2590","article-title":"Hypothalamic circuitry underlying stress-induced insomnia and peripheral immunosuppression","volume":"6","author":"Li","year":"2020","journal-title":"Sci Adv"},{"issue":"2","key":"10.1016\/j.joim.2026.04.002_b0145","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsae224","article-title":"Effects of night-to-night variations in objectively measured sleep on blood glucose in healthy university students","volume":"48","author":"Ng","year":"2025","journal-title":"Sleep"},{"key":"10.1016\/j.joim.2026.04.002_b0150","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2023.1227372","article-title":"Unraveling the associations and causalities between glucose metabolism and multiple sleep traits","volume":"14","author":"Yi","year":"2023","journal-title":"Front Endocrinol (Lausanne)"},{"issue":"20","key":"10.1016\/j.joim.2026.04.002_b0155","doi-asserted-by":"crossref","first-page":"4343","DOI":"10.1016\/j.cub.2023.08.071","article-title":"Suprachiasmatic nucleus promotes hyperglycemia induced by sleep delay","volume":"33","author":"Hurtado-Alvarado","year":"2023","journal-title":"Curr Biol"},{"issue":"1","key":"10.1016\/j.joim.2026.04.002_b0160","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1186\/s12915-024-02097-4","article-title":"Chronic sleep deprivation disturbs energy balance modulated by suprachiasmatic nucleus efferents in mice","volume":"22","author":"Du","year":"2024","journal-title":"BMC Biol"},{"issue":"11","key":"10.1016\/j.joim.2026.04.002_b0165","doi-asserted-by":"crossref","DOI":"10.1111\/cns.70141","article-title":"Dorsal raphe serotonergic neurons-ventral tegmental area neural pathway promotes wake from sleep","volume":"30","author":"Wang","year":"2024","journal-title":"CNS Neurosci Ther"},{"issue":"12","key":"10.1016\/j.joim.2026.04.002_b0170","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsac235","article-title":"Regulation of wakefulness by GABAergic dorsal raphe nucleus-ventral tegmental area pathway","volume":"45","author":"Cai","year":"2022","journal-title":"Sleep"},{"key":"10.1016\/j.joim.2026.04.002_b0175","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2022.877054","article-title":"Functional interaction between GABAergic neurons in the ventral tegmental area and serotonergic neurons in the dorsal raphe nucleus","volume":"16","author":"Rahaman","year":"2022","journal-title":"Front Neurosci"},{"key":"10.1016\/j.joim.2026.04.002_b0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2023.109621","article-title":"Modulation of dopamine from ventral tegmental area neurons by the LC-REM-OFF and PPT-REM-ON neurons in REMS regulation in freely moving rats","volume":"237","author":"Ratna","year":"2023","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.joim.2026.04.002_b0185","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2023.1230428","article-title":"Orexin and MCH neurons: regulators of sleep and metabolism","volume":"17","author":"Bou\u00e2ouda","year":"2023","journal-title":"Front Neurosci"},{"issue":"3","key":"10.1016\/j.joim.2026.04.002_b0190","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsab301","article-title":"Hypocretin in locus coeruleus and dorsal raphe nucleus mediates inescapable footshock stimulation (IFS)-induced REM sleep alteration","volume":"45","author":"Lo","year":"2022","journal-title":"Sleep"},{"issue":"9","key":"10.1016\/j.joim.2026.04.002_b0195","doi-asserted-by":"crossref","first-page":"5213","DOI":"10.1038\/s41380-020-0810-9","article-title":"Dysfunction of ventral tegmental area GABA neurons causes mania-like behavior","volume":"26","author":"Yu","year":"2021","journal-title":"Mol Psychiatry"},{"issue":"5","key":"10.1016\/j.joim.2026.04.002_b0200","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1016\/j.neuron.2018.02.005","article-title":"A hypothalamic switch for REM and non-REM sleep","volume":"97","author":"Chen","year":"2018","journal-title":"Neuron"},{"issue":"2","key":"10.1016\/j.joim.2026.04.002_b0205","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/s00406-022-01534-1","article-title":"Top-down and bottom-up alterations of connectivity patterns of the suprachiasmatic nucleus in chronic insomnia disorder","volume":"274","author":"Yu","year":"2024","journal-title":"Eur Arch Psychiatry Clin Neurosci"},{"key":"10.1016\/j.joim.2026.04.002_b0210","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.brainres.2008.05.060","article-title":"Role of orexin input in the diurnal rhythm of locus coeruleus impulse activity","volume":"1224","author":"Gompf","year":"2008","journal-title":"Brain Res"},{"issue":"4","key":"10.1016\/j.joim.2026.04.002_b0215","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1111\/j.1460-9568.2008.06606.x","article-title":"Circuit projection from suprachiasmatic nucleus to ventral tegmental area: a novel circadian output pathway","volume":"29","author":"Luo","year":"2009","journal-title":"Eur J Neurosci"},{"issue":"17","key":"10.1016\/j.joim.2026.04.002_b0220","doi-asserted-by":"crossref","first-page":"3729","DOI":"10.1016\/j.cub.2021.06.031","article-title":"The NAergic locus coeruleus-ventrolateral preoptic area neural circuit mediates rapid arousal from sleep","volume":"31","author":"Liang","year":"2021","journal-title":"Curr Biol"},{"issue":"35","key":"10.1016\/j.joim.2026.04.002_b0225","doi-asserted-by":"crossref","DOI":"10.1523\/JNEUROSCI.1939-23.2024","article-title":"Role of the locus coeruleus arousal promoting neurons in maintaining brain criticality across the sleep-wake cycle","volume":"44","author":"Huo","year":"2024","journal-title":"J Neurosci"},{"key":"10.1016\/j.joim.2026.04.002_b0230","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2021.634984","article-title":"Novel neuroimaging biomarker for sleep quality in insomnia disorder: a hypothalamus resting state study","volume":"15","author":"Ding","year":"2021","journal-title":"Front Neurosci"},{"issue":"6","key":"10.1016\/j.joim.2026.04.002_b0235","doi-asserted-by":"crossref","first-page":"3026","DOI":"10.1093\/cercor\/bhac258","article-title":"A role of prefrontal cortico-hypothalamic projections in wake promotion","volume":"33","author":"Zhong","year":"2023","journal-title":"Cereb Cortex"},{"issue":"3","key":"10.1016\/j.joim.2026.04.002_b0240","first-page":"402","article-title":"Research progress in the role of the ventral tegmental area-medial prefrontal cortex neural circuit in the regulation of arousal","volume":"46","author":"Hao","year":"2024","journal-title":"Zhongguo Yi Xue Ke Xue Yuan Xue Bao"},{"issue":"9","key":"10.1016\/j.joim.2026.04.002_b0245","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2023.107486","article-title":"Ventrolateral periaqueductal gray GABAergic neurons promote arousal of sevoflurane anesthesia through cortico-midbrain circuit","volume":"26","author":"Guo","year":"2023","journal-title":"iScience"},{"issue":"1","key":"10.1016\/j.joim.2026.04.002_b0250","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.ado9965","article-title":"Mesolimbic dopamine neurons drive infradian rhythms in sleep-wake and heightened activity state","volume":"11","author":"Markam","year":"2025","journal-title":"Sci Adv"},{"issue":"6413","key":"10.1016\/j.joim.2026.04.002_b0255","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1126\/science.aat2512","article-title":"The paraventricular thalamus is a critical thalamic area for wakefulness","volume":"362","author":"Ren","year":"2018","journal-title":"Science"},{"issue":"3","key":"10.1016\/j.joim.2026.04.002_b0260","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1136\/rapm-2023-104964","article-title":"Inhibition of the glutamatergic PVT-NAc projections attenuates local anesthetic-induced neurotoxic behaviors","volume":"50","author":"Zou","year":"2025","journal-title":"Reg Anesth Pain Med"},{"issue":"1","key":"10.1016\/j.joim.2026.04.002_b0265","doi-asserted-by":"crossref","first-page":"1838","DOI":"10.1038\/s41598-020-58711-2","article-title":"Nucleus accumbens pathways control cell-specific gene expression in the medial prefrontal cortex","volume":"10","author":"Hikida","year":"2020","journal-title":"Sci Rep"},{"key":"10.1016\/j.joim.2026.04.002_b0270","doi-asserted-by":"crossref","DOI":"10.1016\/j.nicl.2020.102474","article-title":"Dysfunction of the NAc-mPFC circuit in insomnia disorder","volume":"28","author":"Shao","year":"2020","journal-title":"Neuroimage Clin"},{"key":"10.1016\/j.joim.2026.04.002_b0275","article-title":"Control of behavioral arousal and defense by a glutamatergic midbrain-amygdala pathway in mice","volume":"16","author":"Chen","year":"2022","journal-title":"Front Neurosci"},{"issue":"2","key":"10.1016\/j.joim.2026.04.002_b0280","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.neuron.2019.05.015","article-title":"Sleep regulation by neurotensinergic neurons in a thalamo-amygdala circuit","volume":"103","author":"Ma","year":"2019","journal-title":"Neuron"},{"issue":"11","key":"10.1016\/j.joim.2026.04.002_b0285","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2022.111824","article-title":"A paraventricular thalamus to central amygdala neural circuit modulates acute stress-induced heightened wakefulness","volume":"41","author":"Zhao","year":"2022","journal-title":"Cell Rep"},{"issue":"2","key":"10.1016\/j.joim.2026.04.002_b0290","doi-asserted-by":"crossref","DOI":"10.1136\/gpsych-2023-101183","article-title":"Dual roles of the amygdala-hippocampus circuit in the regulation of rapid eye movement sleep and depression symptoms by repetitive transcranial magnetic stimulation in patients with insomnia","volume":"37","author":"Liu","year":"2024","journal-title":"Gen Psychiatr"},{"issue":"9","key":"10.1016\/j.joim.2026.04.002_b0295","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1038\/s41386-024-01875-6","article-title":"Ventral subiculum promotes wakefulness through several pathways in male mice","volume":"49","author":"Zhang","year":"2024","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.joim.2026.04.002_b0300","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.sleep.2023.10.032","article-title":"Pontine parabrachial nucleus-basal forebrain circuitry regulating cortical and hippocampal arousal","volume":"113","author":"Lv","year":"2024","journal-title":"Sleep Med"},{"issue":"1","key":"10.1016\/j.joim.2026.04.002_b0305","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsac224","article-title":"Amygdala and hippocampus dialogue with neocortex during human sleep and wakefulness","volume":"46","author":"Mu\u00f1oz-Torres","year":"2023","journal-title":"Sleep"},{"issue":"1","key":"10.1016\/j.joim.2026.04.002_b0310","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/s12868-024-00881-0","article-title":"Efferent pathways from the suprachiasmatic nucleus to the horizontal limbs of diagonal band promote NREM sleep during the dark phase in mice","volume":"25","author":"Chen","year":"2024","journal-title":"BMC Neurosci"},{"key":"10.1016\/j.joim.2026.04.002_b0315","article-title":"Distinct hypothalamic paraventricular nucleus inputs to the cingulate cortex and paraventricular thalamic nucleus modulate anxiety and arousal","volume":"13","author":"Liu","year":"2022","journal-title":"Front Pharmacol"},{"key":"10.1016\/j.joim.2026.04.002_b0320","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2022.108979","article-title":"A glutamatergic basal forebrain to midbrain circuit mediates wakefulness and defensive behavior","volume":"208","author":"Cai","year":"2022","journal-title":"Neuropharmacology"},{"issue":"15","key":"10.1016\/j.joim.2026.04.002_b0325","doi-asserted-by":"crossref","first-page":"3301","DOI":"10.1016\/j.cub.2024.06.010","article-title":"A REM-active basal ganglia circuit that regulates anxiety","volume":"34","author":"Ba","year":"2024","journal-title":"Curr Biol"},{"issue":"2","key":"10.1016\/j.joim.2026.04.002_b0330","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1213\/ANE.0000000000006739","article-title":"Ventral tegmental area glutamatergic neurons facilitated emergence from isoflurane anesthesia involves excitation of lateral septum GABA-ergic neurons in mice","volume":"139","author":"Zhang","year":"2024","journal-title":"Anesth Analg"},{"key":"10.1016\/j.joim.2026.04.002_b0335","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.copsyc.2019.12.002","article-title":"Depression and sleep: what has the treatment research revealed and could the HPA axis be a potential mechanism?","volume":"34","author":"Asarnow","year":"2020","journal-title":"Curr Opin Psychol"},{"key":"10.1016\/j.joim.2026.04.002_b0340","doi-asserted-by":"crossref","DOI":"10.1016\/j.yhbeh.2020.104865","article-title":"Acute exposure of rats to a severe stressor alters the circadian pattern of corticosterone and sensitizes to a novel stressor: relationship to pre-stress individual differences in resting corticosterone levels","volume":"126","author":"Belda","year":"2020","journal-title":"Horm Behav"},{"issue":"3","key":"10.1016\/j.joim.2026.04.002_b0345","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1123\/ijsnem.2013-0265","article-title":"Dietary intake, eating behaviors, and diurnal patterns of salivary cortisol and \u03b1-amylase secretion among professional young adult female tennis players","volume":"25","author":"Filaire","year":"2015","journal-title":"Int J Sport Nutr Exerc Metab"},{"key":"10.1016\/j.joim.2026.04.002_b0350","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.bbrc.2021.06.015","article-title":"Circadian misalignment leads to changes in cortisol rhythms, blood biochemical variables and serum miRNA profiles","volume":"567","author":"Huang","year":"2021","journal-title":"Biochem Biophys Res Commun"},{"issue":"11","key":"10.1016\/j.joim.2026.04.002_b0355","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsab130","article-title":"Evening binge alcohol disrupts cardiovagal tone and baroreflex function during polysomnographic sleep","volume":"44","author":"Greenlund","year":"2021","journal-title":"Sleep"},{"issue":"1","key":"10.1016\/j.joim.2026.04.002_b0360","doi-asserted-by":"crossref","DOI":"10.1016\/j.imr.2023.100922","article-title":"Addressing cancer-related fatigue through sleep: a secondary analysis of a randomized trial comparing acupuncture and cognitive behavioral therapy for insomnia","volume":"12","author":"Li","year":"2023","journal-title":"Integr Med Res"},{"issue":"1","key":"10.1016\/j.joim.2026.04.002_b0365","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1186\/s12916-020-01821-5","article-title":"Adverse effects of Z-drugs for sleep disturbance in people living with dementia: a population-based cohort study","volume":"18","author":"Richardson","year":"2020","journal-title":"BMC Med"},{"issue":"7","key":"10.1016\/j.joim.2026.04.002_b0370","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2022.20563","article-title":"Effect of electroacupuncture on insomnia in patients with depression: a randomized clinical trial","volume":"5","author":"Yin","year":"2022","journal-title":"JAMA Netw Open"},{"issue":"11","key":"10.1016\/j.joim.2026.04.002_b0375","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsx153","article-title":"Acupuncture improves peri-menopausal insomnia: a randomized controlled trial","volume":"40","author":"Fu","year":"2017","journal-title":"Sleep"},{"issue":"6","key":"10.1016\/j.joim.2026.04.002_b0380","first-page":"629","article-title":"Acupuncture at \u201cumbilical four-acupoints\u201d for chronic insomnia and its comorbid symptoms","volume":"43","author":"Li","year":"2023","journal-title":"Zhongguo Zhen Jiu"},{"issue":"6","key":"10.1016\/j.joim.2026.04.002_b0385","first-page":"634","article-title":"Bushen Anshen acupuncture for perimenopausal insomnia of kidney-yin deficiency: a randomized controlled trial","volume":"43","author":"Yang","year":"2023","journal-title":"Zhongguo Zhen Jiu"},{"issue":"1","key":"10.1016\/j.joim.2026.04.002_b0390","first-page":"19","article-title":"Regulation action and nerve electrophysiology mechanism of acupuncture on arousal state in patients of primary insomnia","volume":"37","author":"Liu","year":"2017","journal-title":"Zhongguo Zhen Jiu"},{"issue":"2","key":"10.1016\/j.joim.2026.04.002_b0395","first-page":"151","article-title":"Effects of Tiaoshu Anshen acupuncture on sleep quality and serum neurotransmitter levels in patients with chronic insomnia","volume":"45","author":"Liu","year":"2025","journal-title":"Zhongguo Zhen Jiu"},{"issue":"5","key":"10.1016\/j.joim.2026.04.002_b0400","first-page":"4633","article-title":"\u201cGovernor Vessel Daoqi method of acupuncture\u201d combined with estazolam for insomnia: a randomized controlled trial","volume":"38","author":"Ding","year":"2018","journal-title":"Zhongguo Zhen Jiu"},{"issue":"1","key":"10.1016\/j.joim.2026.04.002_b0405","first-page":"326","article-title":"Clinical efficacy of Sun\u2019s abdominal acupuncture combined with CBTI in treating chronic insomnia with anxiety","volume":"31","author":"He","year":"2025","journal-title":"Altern Ther Health Med"},{"issue":"1","key":"10.1016\/j.joim.2026.04.002_b0410","first-page":"3","article-title":"Efficacy comparison of different points combination in the treatment of menopausal insomnia: a randomized controlled trial","volume":"34","author":"Yang","year":"2014","journal-title":"Zhongguo Zhen Jiu"},{"issue":"10","key":"10.1016\/j.joim.2026.04.002_b0415","first-page":"1107","article-title":"Brian effects of electroacupuncture on sleep quality and cognitive function in patients with insomnia related to cerebral infarction","volume":"44","author":"Jiao","year":"2024","journal-title":"Zhongguo Zhen Jiu"},{"issue":"12","key":"10.1016\/j.joim.2026.04.002_b0420","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1007\/s11655-022-3581-0","article-title":"Effect of auricular acupoint bloodletting plus auricular acupressure on sleep quality and neuroendocrine level in college students with primary insomnia: a randomized controlled trial","volume":"28","author":"Chen","year":"2022","journal-title":"Chin J Integr Med"},{"key":"10.1016\/j.joim.2026.04.002_b0425","doi-asserted-by":"crossref","first-page":"271","DOI":"10.2147\/NSS.S247628","article-title":"Effect of acupuncture on pregnancy-related insomnia and melatonin: a single-blinded, randomized, placebo-controlled trial","volume":"12","author":"Foroughinia","year":"2020","journal-title":"Nat Sci Sleep"},{"issue":"45","key":"10.1016\/j.joim.2026.04.002_b0430","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000035942","article-title":"Acupuncture combined with Chinese herbal medicine in the treatment of perimenopausal insomnia: a systematic review and meta-analysis","volume":"102","author":"Li","year":"2023","journal-title":"Medicine (Baltimore)"},{"issue":"11","key":"10.1016\/j.joim.2026.04.002_b0435","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000033213","article-title":"Treatment of insomnia based on the mechanism of pathophysiology by acupuncture combined with herbal medicine: a review","volume":"102","author":"Wang","year":"2023","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.joim.2026.04.002_b0440","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.sleep.2024.05.006","article-title":"Chinese herbal medicine and acupuncture for insomnia in stroke patients: a systematic review and meta-analysis of randomised controlled trials","volume":"120","author":"Su","year":"2024","journal-title":"Sleep Med"},{"issue":"6","key":"10.1016\/j.joim.2026.04.002_b0445","first-page":"1460","article-title":"Clinical efficacy of acupuncture combined with modified Xiangfu Decoction in treatment of menopausal insomnia cause by liver qi stagnation","volume":"45","author":"Yan","year":"2020","journal-title":"Zhongguo Zhong Yao Za Zhi"},{"issue":"51","key":"10.1016\/j.joim.2026.04.002_b0450","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000030703","article-title":"A systematic review and meta-analysis of acupuncture combined with Tuina in the treatment of insomnia","volume":"101","author":"Luo","year":"2022","journal-title":"Medicine (Baltimore)"},{"issue":"4","key":"10.1016\/j.joim.2026.04.002_b0455","first-page":"374","article-title":"Effect of acupuncture combined with low frequency rTMS on comorbid mild-to-moderate depressive disorder and insomnia: a randomized controlled trial","volume":"43","author":"Yan","year":"2023","journal-title":"Zhongguo Zhen Jiu"},{"issue":"12","key":"10.1016\/j.joim.2026.04.002_b0460","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1093\/jnci\/djz050","article-title":"Acupuncture versus cognitive behavioral therapy for insomnia in cancer survivors: a randomized clinical trial","volume":"111","author":"Garland","year":"2019","journal-title":"J Natl Cancer Inst"},{"issue":"2","key":"10.1016\/j.joim.2026.04.002_b0465","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.nec.2010.11.001","article-title":"Overview of functional magnetic resonance imaging","volume":"22","author":"Glover","year":"2011","journal-title":"Neurosurg Clin N Am"},{"issue":"1","key":"10.1016\/j.joim.2026.04.002_b0470","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1186\/s12906-020-02969-6","article-title":"Effectiveness and cerebral responses of multi-points acupuncture for primary insomnia: a preliminary randomized clinical trial and fMRI study","volume":"20","author":"Wang","year":"2020","journal-title":"BMC Complement Med Ther"},{"issue":"1","key":"10.1016\/j.joim.2026.04.002_b0475","doi-asserted-by":"crossref","DOI":"10.1002\/brb3.1927","article-title":"Gender-related difference in altered fractional amplitude of low-frequency fluctuations after electroacupuncture on primary insomnia patients: a resting-state fMRI study","volume":"11","author":"Shi","year":"2021","journal-title":"Brain Behav"},{"issue":"7","key":"10.1016\/j.joim.2026.04.002_b0480","first-page":"767","article-title":"Effect of Jiannao Anshen acupuncture on insomnia: a functional magnetic resonance imaging study","volume":"41","author":"Zhao","year":"2021","journal-title":"Zhongguo Zhen Jiu"},{"issue":"1","key":"10.1016\/j.joim.2026.04.002_b0485","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1186\/s12906-024-04612-0","article-title":"Acupuncture modulates emotional network resting-state functional connectivity in patients with insomnia disorder: a randomized controlled trial and fMRI study","volume":"24","author":"Jiang","year":"2024","journal-title":"BMC Complement Med Ther"},{"key":"10.1016\/j.joim.2026.04.002_b0490","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/465760","article-title":"Differential activation patterns of fMRI in sleep-deprived brain: restoring effects of acupuncture","volume":"2014","author":"Gao","year":"2014","journal-title":"Evid Based Complement Alternat Med"},{"issue":"1","key":"10.1016\/j.joim.2026.04.002_b0495","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1186\/s12906-024-04703-y","article-title":"The altered hypothalamic network functional connectivity in chronic insomnia disorder and regulation effect of acupuncture: a randomized controlled neuroimaging study","volume":"24","author":"Peng","year":"2024","journal-title":"BMC Complement Med Ther"},{"key":"10.1016\/j.joim.2026.04.002_b0500","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2022.947379","article-title":"The altered intrinsic functional connectivity after acupuncture at Shenmen (HT7) in acute sleep deprivation","volume":"13","author":"Ning","year":"2022","journal-title":"Front Neurol"},{"issue":"8","key":"10.1016\/j.joim.2026.04.002_b0505","first-page":"690","article-title":"Effect of Tiaoshen needling on plasma melatonin and cortisol in patients with chronic insomnia","volume":"46","author":"Li","year":"2021","journal-title":"Zhen Ci Yan Jiu"},{"issue":"12","key":"10.1016\/j.joim.2026.04.002_b0510","first-page":"1107","article-title":"Clinical efficacy of shallow-needle therapy combined with estazolam on insomnia of liver stagnation transforming into fire pattern: a randomized controlled trial","volume":"47","author":"Fu","year":"2022","journal-title":"Zhen Ci Yan Jiu"},{"key":"10.1016\/j.joim.2026.04.002_b0515","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1146\/annurev-neuro-071013-014030","article-title":"The brain\u2019s default mode network","volume":"38","author":"Raichle","year":"2015","journal-title":"Annu Rev Neurosci"},{"issue":"8","key":"10.1016\/j.joim.2026.04.002_b0520","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/s11910-018-0861-3","article-title":"Insomnia disorder and brain\u2019s default-mode network","volume":"18","author":"Marques","year":"2018","journal-title":"Curr Neurol Neurosci Rep"},{"key":"10.1016\/j.joim.2026.04.002_b0525","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.jpsychires.2018.05.013","article-title":"The imbalanced anterior and posterior default mode network in the primary insomnia","volume":"103","author":"Yu","year":"2018","journal-title":"J Psychiatr Res"},{"key":"10.1016\/j.joim.2026.04.002_b0530","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.sleep.2022.11.036","article-title":"Altered functional connectivity of anterior cingulate cortex in chronic insomnia: a resting-state fMRI study","volume":"102","author":"Wang","year":"2023","journal-title":"Sleep Med"},{"key":"10.1016\/j.joim.2026.04.002_b0535","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.smrv.2017.10.002","article-title":"The influence of sleep on human hypothalamic-pituitary-adrenal (HPA) axis reactivity: a systematic review","volume":"39","author":"van Dalfsen","year":"2018","journal-title":"Sleep Med Rev"},{"issue":"5","key":"10.1016\/j.joim.2026.04.002_b0540","doi-asserted-by":"crossref","first-page":"3106","DOI":"10.1210\/jc.2004-1056","article-title":"On the interactions of the hypothalamic-pituitary-adrenal (HPA) axis and sleep: normal HPA axis activity and circadian rhythm, exemplary sleep disorders","volume":"90","author":"Buckley","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.joim.2026.04.002_b0545","series-title":"Endotext","article-title":"HPA axis and sleep","author":"Nicolaides","year":"2000"},{"issue":"6","key":"10.1016\/j.joim.2026.04.002_b0550","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1177\/09645284221146197","article-title":"Effects of electroacupuncture on the ventral tegmental area-nucleus accumbens dopamine pathway in rats with chronic sleep deprivation","volume":"41","author":"Xi","year":"2023","journal-title":"Acupunct Med"},{"key":"10.1016\/j.joim.2026.04.002_b0555","doi-asserted-by":"crossref","DOI":"10.1093\/ecam\/nep132","article-title":"Endogenous opiates in the nucleus tractus solitarius mediate electroacupuncture-induced sleep activities in rats","volume":"2011","author":"Cheng","year":"2011","journal-title":"Evid Based Complement Alternat Med"},{"issue":"1","key":"10.1016\/j.joim.2026.04.002_b0560","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/s12929-015-0145-z","article-title":"Low-frequency electroacupuncture suppresses focal epilepsy and improves epilepsy-induced sleep disruptions","volume":"22","author":"Yi","year":"2015","journal-title":"J Biomed Sci"},{"key":"10.1016\/j.joim.2026.04.002_b0565","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/5527060","article-title":"Effects of electroacupuncture on sleep via the dopamine system of the HPA axis in rats after cage change","volume":"2021","author":"Xie","year":"2021","journal-title":"Evid Based Complement Alternat Med"},{"issue":"6","key":"10.1016\/j.joim.2026.04.002_b0570","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1177\/09645284211011489","article-title":"Acupuncture stimulation at HT7 as a non-pharmacological therapy for sleep disorder caused by caffeine administration in rats","volume":"39","author":"Seo","year":"2021","journal-title":"Acupunct Med"},{"key":"10.1016\/j.joim.2026.04.002_b0575","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/3626120","article-title":"Effects of acupuncture treatment in reducing sleep disorder and gut microbiota alterations in PCPA-induced insomnia mice","volume":"2020","author":"Hong","year":"2020","journal-title":"Evid Based Complement Alternat Med"},{"issue":"2","key":"10.1016\/j.joim.2026.04.002_b0580","first-page":"131","article-title":"Effects of acupuncture stimulation of different acupoint groups on sleeping latency, serum and hippocampal TNF-\u03b1 and IL-25 contents in rats with gastric mucosal injury","volume":"40","author":"Huang","year":"2015","journal-title":"Zhen Ci Yan Jiu"},{"issue":"1","key":"10.1016\/j.joim.2026.04.002_b0585","doi-asserted-by":"crossref","DOI":"10.1111\/adb.12862","article-title":"Role of the central amygdala in acupuncture inhibition of methamphetamine-induced behaviors in rats","volume":"26","author":"Kim","year":"2021","journal-title":"Addict Biol"},{"key":"10.1016\/j.joim.2026.04.002_b0590","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2021.119259","article-title":"Electroacupuncture regulates inflammatory cytokines by activating the vagus nerve to enhance antitumor immunity in mice with breast tumors","volume":"272","author":"Zhang","year":"2021","journal-title":"Life Sci"},{"issue":"3","key":"10.1016\/j.joim.2026.04.002_b0595","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0151882","article-title":"Anti-inflammatory effects of acupuncture stimulation via the vagus nerve","volume":"11","author":"Lim","year":"2016","journal-title":"PLoS One"},{"issue":"23","key":"10.1016\/j.joim.2026.04.002_b0600","doi-asserted-by":"crossref","first-page":"5261","DOI":"10.1113\/JP282064","article-title":"Vagus nerve stimulation activates nucleus of solitary tract neurons via supramedullary pathways","volume":"599","author":"Cooper","year":"2021","journal-title":"J Physiol"},{"issue":"1","key":"10.1016\/j.joim.2026.04.002_b0605","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0006-8993(78)91125-3","article-title":"Anatomical evidence of direct projections from the nucleus of the solitary tract to the hypothalamus, amygdala, and other forebrain structures in the rat","volume":"153","author":"Ricardo","year":"1978","journal-title":"Brain Res"},{"key":"10.1016\/j.joim.2026.04.002_b0610","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.neulet.2014.03.018","article-title":"Involvement of amygdaloid neuropeptide Y in the anxiolytic effects of acupuncture during ethanol withdrawal in rats","volume":"567","author":"Zhao","year":"2014","journal-title":"Neurosci Lett"},{"issue":"5","key":"10.1016\/j.joim.2026.04.002_b0615","first-page":"351","article-title":"Involvement of GABAergic projection from central amygdaloid nucleus to paraventricular nucleus of hypothalamus in electroacupuncture-induced regulation of gastric function in Gad2-Cre mice","volume":"45","author":"Wang","year":"2020","journal-title":"Zhen Ci Yan Jiu"},{"key":"10.1016\/j.joim.2026.04.002_b0620","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.neulet.2016.01.004","article-title":"Electroacupuncture regulates hypothalamic-pituitary-adrenal axis and enhances hippocampal serotonin system in a rat model of depression","volume":"615","author":"Le","year":"2016","journal-title":"Neurosci Lett"},{"issue":"10","key":"10.1016\/j.joim.2026.04.002_b0625","doi-asserted-by":"crossref","first-page":"3649","DOI":"10.1210\/EN.2015-1018","article-title":"Effects of acupuncture, RU-486 on the hypothalamic-pituitary-adrenal axis in chronically stressed adult male rats","volume":"156","author":"Eshkevari","year":"2015","journal-title":"Endocrinology"},{"issue":"10","key":"10.1016\/j.joim.2026.04.002_b0630","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1038\/s41575-021-00452-2","article-title":"Gut microbiota as a transducer of dietary cues to regulate host circadian rhythms and metabolism","volume":"18","author":"Choi","year":"2021","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10.1016\/j.joim.2026.04.002_b0635","article-title":"Acupuncture can play an antidepressant role by regulating the intestinal microbes and neurotransmitters in a rat model of depression","volume":"27","author":"Li","year":"2021","journal-title":"Med Sci Monit"},{"issue":"3","key":"10.1016\/j.joim.2026.04.002_b0640","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/s11655-012-1240-6","article-title":"Effects of acupuncture with meridian acupoints and three Anmian acupoints on insomnia and related depression and anxiety state","volume":"19","author":"Huo","year":"2013","journal-title":"Chin J Integr Med"},{"issue":"11","key":"10.1016\/j.joim.2026.04.002_b0645","first-page":"1155","article-title":"Yinyang Ruyin acupuncture on refractory insomnia: a randomized controlled trial","volume":"39","author":"Wang","year":"2019","journal-title":"Zhongguo Zhen Jiu"},{"issue":"7","key":"10.1016\/j.joim.2026.04.002_b0650","first-page":"630","article-title":"Acupoint compatibility effect and mechanism of Shenmen (HT7) and Sanyinjiao (SP6) in improving daytime fatigue and sleepiness of insomnia","volume":"47","author":"Song","year":"2022","journal-title":"Zhen Ci Yan Jiu"},{"key":"10.1016\/j.joim.2026.04.002_b0655","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.copsyc.2019.09.004","article-title":"Sex differences in insomnia and risk for psychopathology in adolescence","volume":"34","author":"Marver","year":"2020","journal-title":"Curr Opin Psychol"},{"issue":"9","key":"10.1016\/j.joim.2026.04.002_b0660","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1007\/s11920-018-0940-9","article-title":"Sex differences in insomnia: from epidemiology and etiology to intervention","volume":"20","author":"Suh","year":"2018","journal-title":"Curr Psychiatry Rep"},{"key":"10.1016\/j.joim.2026.04.002_b0665","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainresbull.2024.111092","article-title":"Infralimbic-basolateral amygdala circuit associated with depression-like not anxiety-like behaviors induced by chronic neuropathic pain and the antidepressant effects of electroacupuncture","volume":"218","author":"Xie","year":"2024","journal-title":"Brain Res Bull"},{"issue":"9","key":"10.1016\/j.joim.2026.04.002_b0670","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2022.32133","article-title":"Effectiveness of acupuncture for anxiety among patients with Parkinson disease: a randomized clinical trial","volume":"5","author":"Fan","year":"2022","journal-title":"JAMA Netw Open"},{"issue":"1","key":"10.1016\/j.joim.2026.04.002_b0675","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/s40659-022-00396-0","article-title":"Acupuncture attenuates comorbid anxiety- and depressive-like behaviors of atopic dermatitis through modulating neuroadaptation in the brain reward circuit in mice","volume":"55","author":"Yeom","year":"2022","journal-title":"Biol Res"},{"key":"10.1016\/j.joim.2026.04.002_b0680","article-title":"Application of machine learning models in predicting insomnia severity: an integrative approach with constitution of traditional Chinese medicine","volume":"10","author":"Li","year":"2023","journal-title":"Front Med (Lausanne)"},{"issue":"1","key":"10.1016\/j.joim.2026.04.002_b0685","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1186\/s12906-023-03926-9","article-title":"Electroacupuncture for the management of symptom clusters in cancer patients and survivors (EAST)","volume":"23","author":"Xie","year":"2023","journal-title":"BMC Complement Med Ther"},{"issue":"6","key":"10.1016\/j.joim.2026.04.002_b0690","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1177\/09645284211026314","article-title":"Auricular acupressure for insomnia associated with attention deficit hyperactivity disorder: a case report","volume":"39","author":"Hong","year":"2021","journal-title":"Acupunct Med"},{"issue":"10","key":"10.1016\/j.joim.2026.04.002_b0695","first-page":"1039","article-title":"Impacts of the repetitive transcranial acupuncture stimulation on the content of serum orexin a in patients with post-stroke insomnia","volume":"38","author":"Hou","year":"2018","journal-title":"Zhongguo Zhen Jiu"}],"container-title":["Journal of Integrative Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2095496426000415?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2095496426000415?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T04:35:14Z","timestamp":1783226114000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2095496426000415"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":139,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["S2095496426000415"],"URL":"https:\/\/doi.org\/10.1016\/j.joim.2026.04.002","relation":{},"ISSN":["2095-4964"],"issn-type":[{"value":"2095-4964","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Current state and future prospects of acupuncture for insomnia: From central mechanisms to peripheral effects","name":"articletitle","label":"Article Title"},{"value":"Journal of Integrative Medicine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joim.2026.04.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Shanghai Yueyang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}