{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T03:38:03Z","timestamp":1791171483395,"version":"4.1.0"},"reference-count":43,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2010,10,1]],"date-time":"2010-10-01T00:00:00Z","timestamp":1285891200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,10,1]],"date-time":"2010-10-01T00:00:00Z","timestamp":1285891200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","joms.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Oral and Maxillofacial Surgery"],"published-print":{"date-parts":[[2010,10]]},"DOI":"10.1016\/j.joms.2009.12.006","type":"journal-article","created":{"date-parts":[[2010,7,16]],"date-time":"2010-07-16T05:28:17Z","timestamp":1279258097000},"page":"2459-2467","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Reconstruction of the Mandible Using Preshaped 2.3-mm Titanium Plates, Autogenous Cortical Bone Plates, Particulate Cancellous Bone, and Platelet-Rich Plasma: A Retrospective Analysis of 20 Patients"],"prefix":"10.1016","volume":"68","author":[{"given":"Robert E.C.M.","family":"Mooren","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias A.W.","family":"Merkx","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter A.W.H.","family":"Kessler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A.","family":"Jansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul J.W.","family":"Stoelinga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.joms.2009.12.006_bib1","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1111\/j.1600-0501.2005.01212.x","article-title":"Clinical outcome of dental implants placed in fibula-free flaps used for the reconstruction of maxillo-mandibular defects following ablation for tumors or osteoradionecrosis","volume":"17","author":"Chiapasco","year":"2006","journal-title":"Clin Oral Implants Res"},{"key":"10.1016\/j.joms.2009.12.006_bib2","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.tripleo.2007.04.002","article-title":"Vascularized free fibular flap for the reconstruction of mandibular defects: Clinical experience in 42 cases","volume":"106","author":"Gonz\u00e1lez-Garc\u00eda","year":"2008","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.joms.2009.12.006_bib3","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1097\/00006534-198907000-00014","article-title":"Fibular free flap: A new method of mandible reconstruction","volume":"84","author":"Hidalgo","year":"1989","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.joms.2009.12.006_bib4","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1054\/bjom.2001.0706","article-title":"Health related quality of life and clinical function after primary surgery for oral cancer","volume":"40","author":"Rogers","year":"2002","journal-title":"Br J Oral Maxillofac Surg"},{"key":"10.1016\/j.joms.2009.12.006_bib5","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1288\/00005537-199109000-00004","article-title":"Functional evaluation following microvascular oromandibular reconstruction of the oral cancer patient: A comparative study of reconstructed and nonreconstructed patients","volume":"101","author":"Urken","year":"1991","journal-title":"Laryngoscope"},{"key":"10.1016\/j.joms.2009.12.006_bib6","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.ijom.2008.03.002","article-title":"Mandibular reconstruction in adults: A review","volume":"37","author":"Goh","year":"2008","journal-title":"Int J Oral Maxillofac Surg"},{"key":"10.1016\/j.joms.2009.12.006_bib7","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1016\/S0278-2391(97)90165-8","article-title":"A comparison of vascularized and nonvascularized bone grafts for reconstruction of mandibular continuity defects","volume":"55","author":"Pogrel","year":"1997","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.joms.2009.12.006_bib8","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1001\/archotol.1991.01870190045010","article-title":"Oromandibular reconstruction using microvascular composite free flaps","volume":"117","author":"Urken","year":"1991","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.joms.2009.12.006_bib9","first-page":"46","article-title":"Arch oromandibular reconstruction using microvascular composite flaps: Report of 210 cases","volume":"124","author":"Urken","year":"1998","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.joms.2009.12.006_bib10","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.bjoms.2005.07.018","article-title":"Trends in head and neck microvascular reconstructive surgery in Liverpool (1992-2001)","volume":"44","author":"Brown","year":"2006","journal-title":"Br J Oral Maxillofac Surg"},{"key":"10.1016\/j.joms.2009.12.006_bib11","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.ijom.2007.01.024","article-title":"The evolution of preimplant surgery from preprosthetic surgery","volume":"36","author":"Cawood","year":"2007","journal-title":"Int J Oral Maxillofac Surg"},{"key":"10.1016\/j.joms.2009.12.006_bib12","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0901-5027(96)80004-X","article-title":"Oral rehabilitation with endosteal implants and free flaps","volume":"25","author":"Hayter","year":"1996","journal-title":"Int J Oral Maxillofac Surg"},{"key":"10.1016\/j.joms.2009.12.006_bib13","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1016\/S0278-2391(10)80501-4","article-title":"Mandibular reconstruction","volume":"51","author":"Marx","year":"1993","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.joms.2009.12.006_bib14","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1097\/01.scs.0000244921.07383.cc","article-title":"Reconstruction of mandibular defects using autografts combined with demineralized bone matrix and cancellous allograft","volume":"18","author":"Canter","year":"2007","journal-title":"J Craniofac Surg"},{"key":"10.1016\/j.joms.2009.12.006_bib15","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1002\/(SICI)1097-0347(199901)21:1<66::AID-HED9>3.0.CO;2-Z","article-title":"Vascularized bone flaps versus nonvascularized bone grafts for mandibular reconstruction: An outcome analysis of primary bony union and endosseous implant success","volume":"21","author":"Foster","year":"1999","journal-title":"Head Neck"},{"key":"10.1016\/j.joms.2009.12.006_bib16","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1016\/S0278-2391(99)90015-0","article-title":"Comparison of the late results of mandibular reconstruction using nonvascularized or vascularized grafts and dental implants","volume":"57","author":"Schliephake","year":"1999","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.joms.2009.12.006_bib17","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0278-2391(94)90440-5","article-title":"Mandibular reconstruction with the Dacron urethane tray: A radiologic assessment of bone remodeling","volume":"52","author":"Cheung","year":"1994","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.joms.2009.12.006_bib18","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1111\/j.1834-7819.1999.tb00221.x","article-title":"Custom-made titanium mandibular reconstruction tray","volume":"44","author":"Samman","year":"1999","journal-title":"Aust Dent J"},{"key":"10.1016\/j.joms.2009.12.006_bib19","first-page":"1","article-title":"Mandibular defect reconstruction using three-dimensional polycaprolactone scaffold in combination with platelet-rich plasma and recombinant human bone morphogenetic protein-2: De novo synthesis of bone in a single case","volume":"14","author":"Schuckert","year":"2008","journal-title":"Tissue Eng Part A"},{"key":"10.1016\/j.joms.2009.12.006_bib20","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/S1079-2104(98)90029-4","article-title":"Platelet-rich plasma: Growth factor enhancement for bone grafts","volume":"85","author":"Marx","year":"1998","journal-title":"Oral Surg Oral Med Oral Pathol Radiol Endod"},{"key":"10.1016\/j.joms.2009.12.006_bib21","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/0278-2391(94)90401-4","article-title":"Autologous fibrin adhesive in mandibular reconstruction with particulate cancellous bone and marrow","volume":"52","author":"Tayaponsak","year":"1994","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.joms.2009.12.006_bib22","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1016\/S0278-2391(97)90187-7","article-title":"Platelet gel: An autologous alternative to fibrin glue with applications in oral and maxillofacial surgery","volume":"55","author":"Whitman","year":"1997","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.joms.2009.12.006_bib23","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/j.ijom.2004.06.003","article-title":"Reconstruction of the mandible using preshaped 2.3 mm titanium plates, autogenous particulate cortico-cancellous bone grafts and platelet-rich plasma: A report on eight patients","volume":"33","author":"Merkx","year":"2004","journal-title":"Int J Oral Maxillofac Surg"},{"key":"10.1016\/j.joms.2009.12.006_bib24","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.ijom.2005.10.009","article-title":"Reconstruction of the mandible after ablative surgery for the treatment of aggressive, benign odontogenic tumours in Tanzania: A preliminary study","volume":"35","author":"Simon","year":"2006","journal-title":"Int J Oral Maxillofac Surg"},{"key":"10.1016\/j.joms.2009.12.006_bib25","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1054\/ijom.2003.0461","article-title":"Autologous fibrin glue with growth factors in reconstructive maxillofacial surgery","volume":"33","author":"Thorn","year":"2004","journal-title":"Int J Oral Maxillofac Surg"},{"key":"10.1016\/j.joms.2009.12.006_bib26","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1054\/ijom.2003.0452","article-title":"Mandibular reconstruction: A histological and histomorphometric study on the use of autogenous scaffolds, particulate cortico-cancellous bone grafts and platelet-rich plasma in goats","volume":"33","author":"Fennis","year":"2004","journal-title":"Int J Oral Maxillofac Surg"},{"key":"10.1016\/j.joms.2009.12.006_bib27","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/j.ijom.2007.03.013","article-title":"The effect of platelet-rich plasma on early and late bone healing: An experimental study in goats","volume":"36","author":"Mooren","year":"2007","journal-title":"Int J Oral Maxillofac Surg"},{"key":"10.1016\/j.joms.2009.12.006_bib28","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1111\/j.1600-0501.2006.01327.x","article-title":"Early effect of platelet-rich plasma on bone healing in combination with an osteoconductive material in rat cranial defects","volume":"18","author":"Plachokova","year":"2007","journal-title":"Clin Oral Implants Res"},{"key":"10.1016\/j.joms.2009.12.006_bib29","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1097\/00006534-199707000-00005","article-title":"Regional differences of dura osteoinduction: Squamous dura induces osteogenesis, sutural dura induces chondrogenesis and osteogenesis","volume":"100","author":"Yu","year":"1997","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.joms.2009.12.006_bib30","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1097\/00006534-198403000-00005","article-title":"The influence of the recipient site on bone grafts to the face","volume":"73","author":"Zins","year":"1984","journal-title":"Plast Reconstr Surg"},{"key":"10.1016\/j.joms.2009.12.006_bib31","doi-asserted-by":"crossref","first-page":"2029","DOI":"10.1016\/S0142-9612(99)00105-2","article-title":"Incorporation of particulate bone grafts in the facial skeleton","volume":"20","author":"Merkx","year":"1999","journal-title":"Biomaterials"},{"key":"10.1016\/j.joms.2009.12.006_bib32","doi-asserted-by":"crossref","first-page":"6524","DOI":"10.1128\/IAI.70.12.6524-6533.2002","article-title":"Antimicrobial peptides from human platelets","volume":"70","author":"Tang","year":"2002","journal-title":"Infect Immun"},{"key":"10.1016\/j.joms.2009.12.006_bib33","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1302\/0301-620X.89B3.18491","article-title":"Antibacterial effect of autologous platelet gel enriched with growth factors and other active substances: An in vitro study","volume":"89","author":"Bielecki","year":"2007","journal-title":"J Bone Joint Surg Br"},{"key":"10.1016\/j.joms.2009.12.006_bib34","doi-asserted-by":"crossref","first-page":"20374","DOI":"10.1074\/jbc.275.27.20374","article-title":"Microbicidal proteins from human blood platelets, are C-terminal deletion products of CXC chemokines","volume":"275","author":"Krijgsveld","year":"2000","journal-title":"J Biol Chem"},{"key":"10.1016\/j.joms.2009.12.006_bib35","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1086\/516120","article-title":"The role of platelets in antimicrobial host defense","volume":"25","author":"Yeaman","year":"1997","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.joms.2009.12.006_bib36","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1002\/jbmr.5650060509","article-title":"Inhibiting and stimulating effects of TGF-beta 1 on osteoclastic bone resorption in fetal mouse bone organ cultures","volume":"6","author":"Dieudonn\u00e9","year":"1991","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.joms.2009.12.006_bib37","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1046\/j.1524-475X.2002.10510.x","article-title":"Fibroblast proliferation due to exposure to a platelet concentrate in vitro is pH dependent","volume":"10","author":"Liu","year":"2002","journal-title":"Wound Repair Regen"},{"key":"10.1016\/j.joms.2009.12.006_bib38","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.joms.2003.12.003","article-title":"Platelet-rich plasma: Evidence to support its use","volume":"62","author":"Marx","year":"2004","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.joms.2009.12.006_bib39","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1007\/s10006-002-0367-6","article-title":"Growth stimulation of human osteoblast-like cells by thrombocyte concentrates in vitro","volume":"6","author":"Weibrich","year":"2002","journal-title":"Mund Kiefer Gesichtschir"},{"key":"10.1016\/j.joms.2009.12.006_bib40","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/j.bone.2003.12.010","article-title":"Effect of platelet concentration in platelet-rich plasma on peri-implant bone regeneration","volume":"34","author":"Weibrich","year":"2004","journal-title":"Bone"},{"key":"10.1016\/j.joms.2009.12.006_bib41","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1111\/j.1600-0501.2005.01203.x","article-title":"The in vitro effect of different PRP concentrations on osteoblasts and fibroblasts","volume":"17","author":"Graziani","year":"2006","journal-title":"Clin Oral Implants Res"},{"key":"10.1016\/j.joms.2009.12.006_bib42","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.bbrc.2008.08.014","article-title":"The content of bone morphogenetic proteins in platelets varies greatly between different platelet donors","volume":"17","author":"Kal\u00e9n","year":"2008","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.joms.2009.12.006_bib43","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.bbrc.2007.06.142","article-title":"Platelet-rich plasma stimulates osteoblastic differentiation in the presence of BMPs","volume":"361","author":"Tomoyasu","year":"2007","journal-title":"Biochem Biophys Res Commun"}],"container-title":["Journal of Oral and Maxillofacial Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278239109021181?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278239109021181?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T16:34:31Z","timestamp":1759509271000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0278239109021181"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,10]]},"references-count":43,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2010,10]]}},"alternative-id":["S0278239109021181"],"URL":"https:\/\/doi.org\/10.1016\/j.joms.2009.12.006","relation":{},"ISSN":["0278-2391"],"issn-type":[{"value":"0278-2391","type":"print"}],"subject":[],"published":{"date-parts":[[2010,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Reconstruction of the Mandible Using Preshaped 2.3-mm Titanium Plates, Autogenous Cortical Bone Plates, Particulate Cancellous Bone, and Platelet-Rich Plasma: A Retrospective Analysis of 20 Patients","name":"articletitle","label":"Article Title"},{"value":"Journal of Oral and Maxillofacial Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joms.2009.12.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}