{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T00:17:44Z","timestamp":1783642664851,"version":"3.55.0"},"reference-count":33,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","joms.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Oral and Maxillofacial Surgery"],"published-print":{"date-parts":[[2018,8]]},"DOI":"10.1016\/j.joms.2017.11.012","type":"journal-article","created":{"date-parts":[[2017,11,21]],"date-time":"2017-11-21T23:45:32Z","timestamp":1511307932000},"page":"1794-1799","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Nodal Stage: Is It a Prognostic Factor for Submandibular Gland Cancer?"],"prefix":"10.1016","volume":"76","author":[{"given":"Yanbin","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lizheng","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RunTao","family":"Zhuang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhengxue","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.joms.2017.11.012_bib1","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1002\/path.1711460106","article-title":"Salivary gland tumours. A review of 2410 cases with particular reference to histological types, site, age and sex distribution","volume":"146","author":"Eveson","year":"1985","journal-title":"J Pathol"},{"key":"10.1016\/j.joms.2017.11.012_bib2","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1002\/hed.2890080309","article-title":"Salivary neoplasms: Overview of a 35-year experience with 2,807 patients","volume":"8","author":"Spiro","year":"1986","journal-title":"Head Neck Surg"},{"key":"10.1016\/j.joms.2017.11.012_bib3","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.joms.2003.06.012","article-title":"Survival and prognosis for cancer of the submandibular gland","volume":"62","author":"Bhattacharyya","year":"2004","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.joms.2017.11.012_bib4","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1177\/000348948609500223","article-title":"Carcinomas of the submandibular and sublingual glands","volume":"95","author":"Batsakis","year":"1986","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"10.1016\/j.joms.2017.11.012_bib5","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1001\/archotol.1990.01870090071011","article-title":"Submandibular gland tumors. Adverse histologic factors and therapeutic implications","volume":"116","author":"Weber","year":"1990","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.joms.2017.11.012_bib6","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1016\/j.joms.2006.02.036","article-title":"Submandibular gland excision: 15 Years of experience","volume":"65","author":"Preuss","year":"2007","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.joms.2017.11.012_bib7","first-page":"1575","article-title":"MR of the submandibular gland: Normal and pathologic states","volume":"17","author":"Kaneda","year":"1996","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.joms.2017.11.012_bib8","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1054\/bjps.1996.0210","article-title":"Malignant tumours of the submandibular salivary gland: A 15-year review","volume":"51","author":"Camilleri","year":"1998","journal-title":"Br J Plast Surg"},{"key":"10.1016\/j.joms.2017.11.012_bib9","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/S0002-9610(73)80030-3","article-title":"Malignant tumors of the submaxillary gland","volume":"126","author":"Byers","year":"1973","journal-title":"Am J Surg"},{"key":"10.1016\/j.joms.2017.11.012_bib10","doi-asserted-by":"crossref","first-page":"2104","DOI":"10.1016\/j.joms.2009.09.030","article-title":"Prognostic factors and outcome analysis of submandibular gland cancer: A clinical audit","volume":"68","author":"Mallik","year":"2010","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.joms.2017.11.012_bib11","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1001\/archotol.133.6.546","article-title":"Effect of initial treatment on disease outcome for patients with submandibular gland carcinoma","volume":"133","author":"Kaszuba","year":"2007","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.joms.2017.11.012_bib12","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1177\/000348947208100303","article-title":"Analysis of 115 patients with tumors of the submandibular gland","volume":"81","author":"Conley","year":"1972","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"10.1016\/j.joms.2017.11.012_bib13","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1097\/00000421-198612000-00009","article-title":"Malignant parotid tumors. Prognostic factors and optimum treatment","volume":"9","author":"Theriault","year":"1986","journal-title":"Am J Clin Oncol"},{"key":"10.1016\/j.joms.2017.11.012_bib14","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.oraloncology.2010.01.011","article-title":"Primary tumors of the submandibular glands: A retrospective study based on 41 cases","volume":"46","author":"Ziglinas","year":"2010","journal-title":"Oral Oncol"},{"key":"10.1016\/j.joms.2017.11.012_bib15","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1002\/(SICI)1097-0142(19990515)85:10<2255::AID-CNCR22>3.0.CO;2-D","article-title":"Prognostic factors for long term results of the treatment of patients with malignant submandibular gland tumors","volume":"85","author":"Vander Poorten","year":"1999","journal-title":"Cancer"},{"key":"10.1016\/j.joms.2017.11.012_bib16","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1080\/00016480310016406","article-title":"Management of malignant submandibular gland tumors","volume":"123","author":"Rinaldo","year":"2003","journal-title":"Acta Otolaryngol"},{"key":"10.1016\/j.joms.2017.11.012_bib17","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1016\/j.otohns.2004.06.705","article-title":"Adenoid cystic carcinoma of the submandibular gland: A 35-year review","volume":"131","author":"Cohen","year":"2004","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.joms.2017.11.012_bib18","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1001\/archotol.1989.01860270058015","article-title":"Carcinoma of major salivary glands. Recent trends","volume":"115","author":"Spiro","year":"1989","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.joms.2017.11.012_bib19","doi-asserted-by":"crossref","first-page":"1974","DOI":"10.1002\/cncr.23393","article-title":"Smoking and risk of parotid gland tumors: A nationwide case-control study","volume":"112","author":"Sadetzki","year":"2008","journal-title":"Cancer"},{"key":"10.1016\/j.joms.2017.11.012_bib20","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1001\/archotol.1990.01870100057012","article-title":"Salivary gland cancer. A case-control investigation of risk factors","volume":"116","author":"Spitz","year":"1990","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.joms.2017.11.012_bib21","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1097\/00001648-199707000-00011","article-title":"Environmental factors and the risk of salivary gland cancer","volume":"8","author":"Horn-Ross","year":"1997","journal-title":"Epidemiology"},{"key":"10.1016\/j.joms.2017.11.012_bib22","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1017\/S0022215100098807","article-title":"Salivary duct adenocarcinoma: A high grade malignancy","volume":"100","author":"Hui","year":"1986","journal-title":"J Laryngol Otol"},{"key":"10.1016\/j.joms.2017.11.012_bib23","first-page":"774","article-title":"Polymorphous low-grade adenocarcinoma of submandibular gland origin","volume":"43","author":"Haba","year":"1993","journal-title":"Acta Pathol Jpn"},{"key":"10.1016\/j.joms.2017.11.012_bib24","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1067\/mhn.2000.108200","article-title":"Polymorphous low-grade adenocarcinoma of the submandibular gland","volume":"123","author":"Cinamon","year":"2000","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.joms.2017.11.012_bib25","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0385-8146(00)00107-3","article-title":"Basal cell adenocarcinomas of the submandibular and parotid glands recognized simultaneously: Report of a case","volume":"28","author":"Takeuchi","year":"2001","journal-title":"Auris Nasus Larynx"},{"key":"10.1016\/j.joms.2017.11.012_bib26","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1007\/s00428-001-0565-x","article-title":"Sebaceous differentiation in basal cell adenocarcinoma of the submandibular gland","volume":"440","author":"Ide","year":"2002","journal-title":"Virchows Arch"},{"key":"10.1016\/j.joms.2017.11.012_bib27","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0196-0709(92)90008-H","article-title":"Malignant salivary gland tumors: Squamous cell carcinoma of the submandibular gland in a child","volume":"13","author":"Rasp","year":"1992","journal-title":"Am J Otolaryngol"},{"key":"10.1016\/j.joms.2017.11.012_bib28","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1001\/archotol.128.8.904","article-title":"Nodal metastasis in major salivary gland cancer: Predictive factors and effects on survival","volume":"128","author":"Bhattacharyya","year":"2002","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.joms.2017.11.012_bib29","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.oraloncology.2007.02.004","article-title":"Diagnosis and management of neoplastic lesions of the submandibular triangle","volume":"44","author":"Munir","year":"2008","journal-title":"Oral Oncol"},{"key":"10.1016\/j.joms.2017.11.012_bib30","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1002\/1097-0142(19920201)69:3<615::AID-CNCR2820690303>3.0.CO;2-9","article-title":"The indications for elective treatment of the neck in cancer of the major salivary glands","volume":"69","author":"Armstrong","year":"1992","journal-title":"Cancer"},{"key":"10.1016\/j.joms.2017.11.012_bib31","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1097\/00000421-198802000-00010","article-title":"Malignant submandibular gland tumors. A review of 91 patients","volume":"11","author":"Bissett","year":"1988","journal-title":"Am J Clin Oncol"},{"key":"10.1016\/j.joms.2017.11.012_bib32","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1001\/archotol.1990.01870030054008","article-title":"Malignant tumors of major salivary gland origin. A matched-pair analysis of the role of combined surgery and postoperative radiotherapy","volume":"116","author":"Armstrong","year":"1990","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.joms.2017.11.012_bib33","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1016\/S0360-3016(01)01724-2","article-title":"Postoperative radiotherapy for malignant tumors of the submandibular gland","volume":"51","author":"Storey","year":"2001","journal-title":"Int J Radiat Oncol Biol Phys"}],"container-title":["Journal of Oral and Maxillofacial Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278239117314325?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278239117314325?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T16:55:45Z","timestamp":1759510545000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0278239117314325"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8]]},"references-count":33,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2018,8]]}},"alternative-id":["S0278239117314325"],"URL":"https:\/\/doi.org\/10.1016\/j.joms.2017.11.012","relation":{},"ISSN":["0278-2391"],"issn-type":[{"value":"0278-2391","type":"print"}],"subject":[],"published":{"date-parts":[[2018,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Nodal Stage: Is It a Prognostic Factor for Submandibular Gland Cancer?","name":"articletitle","label":"Article Title"},{"value":"Journal of Oral and Maxillofacial Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joms.2017.11.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier Inc on behalf of the American Association of Oral and Maxillofacial Surgeons","name":"copyright","label":"Copyright"}]}}