{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T14:35:32Z","timestamp":1790778932157,"version":"4.1.0"},"reference-count":24,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100017661","name":"China Health Promotion Foundation","doi-asserted-by":"publisher","award":["0715"],"award-info":[{"award-number":["0715"]}],"id":[{"id":"10.13039\/501100017661","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","joms.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Oral and Maxillofacial Surgery"],"published-print":{"date-parts":[[2023,1]]},"DOI":"10.1016\/j.joms.2022.09.008","type":"journal-article","created":{"date-parts":[[2022,9,15]],"date-time":"2022-09-15T23:41:39Z","timestamp":1663285299000},"page":"8-16","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"title":["Can Remimazolam Be a New Sedative Option for Outpatients Undergoing Ambulatory Oral and Maxillofacial Surgery?"],"prefix":"10.1016","volume":"81","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3078-294X","authenticated-orcid":false,"given":"Zijian","family":"Guo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaodong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Likuan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6722-0708","authenticated-orcid":false,"given":"Xudong","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.joms.2022.09.008_bib1","doi-asserted-by":"crossref","first-page":"502","DOI":"10.14219\/jada.archive.2006.0223","article-title":"Balancing efficacy and safety in the use of oral sedation in dental outpatients","volume":"137","author":"Dionne","year":"2006","journal-title":"J Am Dent Assoc"},{"key":"10.1016\/j.joms.2022.09.008_bib2","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/s10006-015-0488-3","article-title":"Comparative study of hemodynamic changes caused by diazepam and midazolam during third molar surgery: A randomized controlled trial","volume":"19","author":"de Morais","year":"2015","journal-title":"Oral Maxillofac Surg"},{"key":"10.1016\/j.joms.2022.09.008_bib3","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/s10006-015-0502-9","article-title":"Safety of adjunct pre-emptive intravenous tramadol with midazolam sedation for third molar surgery","volume":"19","author":"Eriksson","year":"2015","journal-title":"Oral Maxillofac Surg"},{"key":"10.1016\/j.joms.2022.09.008_bib4","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1136\/rapm-2021-102989","article-title":"Association of perioperative midazolam use and complications: A population-based analysis","volume":"47","author":"Athanassoglou","year":"2022","journal-title":"Reg Anesth Pain Med"},{"key":"10.1016\/j.joms.2022.09.008_bib6","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.chest.2018.09.015","article-title":"Safety and efficacy of remimazolam compared with placebo and midazolam for moderate sedation during bronchoscopy","volume":"155","author":"Pastis","year":"2019","journal-title":"Chest"},{"key":"10.1016\/j.joms.2022.09.008_bib7","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.gie.2018.04.2351","article-title":"A phase III study evaluating the efficacy and safety of remimazolam (CNS 7056) compared with placebo and midazolam in patients undergoing colonoscopy","volume":"88","author":"Rex","year":"2018","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.joms.2022.09.008_bib8","series-title":"Sample Size Calculations in Clinical Research","first-page":"265","author":"Chow","year":"2017"},{"key":"10.1016\/j.joms.2022.09.008_bib9","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1097\/LBR.0000000000000784","article-title":"Correlation of vital signs and depth of sedation by modified observer\u2019s assessment of alertness and sedation (MOAA\/S) scale in bronchoscopy","volume":"29","author":"Pastis","year":"2022","journal-title":"J Bronchology Interv Pulmonol"},{"key":"10.1016\/j.joms.2022.09.008_bib10","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1097\/EJA.0000000000000683","article-title":"European Society of Anaesthesiology and European Board of Anaesthesiology guidelines for procedural sedation and analgesia in adults","volume":"35","author":"Hinkelbein","year":"2018","journal-title":"Eur J Anaesthesiol"},{"key":"10.1016\/j.joms.2022.09.008_bib11","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1213\/ANE.0000000000000548","article-title":"A Phase IIa, randomized, double-blind study of remimazolam (CNS 7056) versus midazolam for sedation in upper gastrointestinal endoscopy","volume":"120","author":"Borkett","year":"2015","journal-title":"Anesth Analg"},{"key":"10.1016\/j.joms.2022.09.008_bib12","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1016\/j.gie.2015.08.062","article-title":"A phase IIb study comparing the safety and efficacy of remimazolam and midazolam in patients undergoing colonoscopy","volume":"83","author":"Pambianco","year":"2016","journal-title":"Gastrointest Endosc"},{"key":"10.1016\/j.joms.2022.09.008_bib13","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.dld.2020.10.039","article-title":"Safety and efficacy of remimazolam in high risk colonoscopy: A randomized trial","volume":"53","author":"Rex","year":"2021","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.joms.2022.09.008_bib14","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1007\/s40265-021-01544-8","article-title":"Remimazolam: A review in procedural sedation","volume":"81","author":"Lee","year":"2021","journal-title":"Drugs"},{"key":"10.1016\/j.joms.2022.09.008_bib15","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1007\/s00540-021-03030-7","article-title":"Neurological sedative indicators during general anesthesia with remimazolam","volume":"36","author":"Shirozu","year":"2022","journal-title":"J Anesth"},{"key":"10.1016\/j.joms.2022.09.008_bib16","doi-asserted-by":"crossref","first-page":"678","DOI":"10.3390\/medicina55100678","article-title":"Psychological Factors in dental patient care: Odontophobia","volume":"55","author":"De Stefano","year":"2019","journal-title":"Medicina (Kaunas)"},{"key":"10.1016\/j.joms.2022.09.008_bib17","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.cden.2015.11.002","article-title":"Oral sedation in the dental Office","volume":"60","author":"Sebastiani","year":"2016","journal-title":"Dent Clin North Am"},{"key":"10.1016\/j.joms.2022.09.008_bib18","series-title":"Procedural sedation. StatPearls","author":"Benzoni","year":"2022"},{"key":"10.1016\/j.joms.2022.09.008_bib19","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1097\/ACO.0000000000000877","article-title":"Remimazolam for anaesthesia or sedation","volume":"33","author":"Sneyd","year":"2020","journal-title":"Curr Opin Anaesthesiol"},{"key":"10.1016\/j.joms.2022.09.008_bib20","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.mayocpiqo.2017.10.002","article-title":"Overall cost comparison of gastrointestinal endoscopic procedures with endoscopist- or anesthesia-supported sedation by activity-based costing techniques","volume":"1","author":"Helmers","year":"2017","journal-title":"Mayo Clin Proc Innov Qual Outcomes"},{"key":"10.1016\/j.joms.2022.09.008_bib21","first-page":"1","article-title":"Efficacy and safety of remimazolam in procedural sedation and analgesia: A protocol for systematic review and meta analysis","volume":"99","author":"Wang","year":"2020","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.joms.2022.09.008_bib22","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1097\/01.anes.0000267503.85085.c0","article-title":"CNS 7056: A novel ultra-short-acting benzodiazepine","volume":"107","author":"Kilpatrick","year":"2007","journal-title":"Anesthesiology"},{"key":"10.1016\/j.joms.2022.09.008_bib23","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1213\/ANE.0b013e3182a705ae","article-title":"A phase Ib, dose-finding study of multiple doses of remimazolam (CNS 7056) in volunteers undergoing colonoscopy","volume":"117","author":"Worthington","year":"2013","journal-title":"Anesth Analg"},{"key":"10.1016\/j.joms.2022.09.008_bib24","doi-asserted-by":"crossref","first-page":"122","DOI":"10.2344\/0003-3006(2005)52[122:ASP]2.0.CO;2","article-title":"A survey of pain, pressure, and discomfort induced by commonly used oral local anesthesia injections","volume":"52","author":"Kaufman","year":"2005","journal-title":"Anesth Prog"},{"key":"10.1016\/j.joms.2022.09.008_bib25","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/s10006-017-0628-z","article-title":"Infiltrative local anesthesia with articaine is equally as effective as inferior alveolar nerve block with lidocaine for the removal of erupted molars","volume":"21","author":"Venkat Narayanan","year":"2017","journal-title":"Oral Maxillofac Surg"}],"container-title":["Journal of Oral and Maxillofacial Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278239122008941?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278239122008941?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T10:35:12Z","timestamp":1777545312000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0278239122008941"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["S0278239122008941"],"URL":"https:\/\/doi.org\/10.1016\/j.joms.2022.09.008","relation":{},"ISSN":["0278-2391"],"issn-type":[{"value":"0278-2391","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Can Remimazolam Be a New Sedative Option for Outpatients Undergoing Ambulatory Oral and Maxillofacial Surgery?","name":"articletitle","label":"Article Title"},{"value":"Journal of Oral and Maxillofacial Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joms.2022.09.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 American Association of Oral and Maxillofacial Surgeons","name":"copyright","label":"Copyright"}]}}