{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T10:47:02Z","timestamp":1780570022081,"version":"3.54.1"},"reference-count":27,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1TR003098"],"award-info":[{"award-number":["UL1TR003098"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019822","name":"Institute for Clinical and Translational Research, University of Maryland, Baltimore","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019822","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005902","name":"Institute for Clinical and Translational Research, University of Wisconsin, Madison","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005902","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","joms.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Oral and Maxillofacial Surgery"],"published-print":{"date-parts":[[2024,3]]},"DOI":"10.1016\/j.joms.2024.01.001","type":"journal-article","created":{"date-parts":[[2024,1,4]],"date-time":"2024-01-04T12:31:09Z","timestamp":1704371469000},"page":"332-340","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Risk Factors for Infection Recurrence After Surgical Resection of Advanced Stage Osteonecrosis of the Mandible"],"prefix":"10.1016","volume":"82","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4977-0968","authenticated-orcid":false,"given":"James B.","family":"Doub","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4010-853X","authenticated-orcid":false,"given":"Cameron","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donita","family":"Dyalram","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pauline","family":"Shih","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William S.","family":"Twaddell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6021-3516","authenticated-orcid":false,"given":"Joshua E.","family":"Lubek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.joms.2024.01.001_bib1","doi-asserted-by":"crossref","first-page":"23","DOI":"10.3390\/dj11010023","article-title":"Osteonecrosis of the jaw","volume":"11","author":"Lon\u010dar Brzak","year":"2023","journal-title":"Dent J (Basel)"},{"key":"10.1016\/j.joms.2024.01.001_bib2","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.oooo.2018.09.008","article-title":"Medication-related osteonecrosis of the jaw: Definition and best practice for prevention, diagnosis, and treatment","volume":"127","author":"Nicolatou-Galitis","year":"2019","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"10.1016\/j.joms.2024.01.001_bib3","first-page":"37","article-title":"New trends in adjunctive treatment and diagnosis in medication-related osteonecrosis of the jaw: A 10-year review","volume":"34","author":"De Santis","year":"2020","journal-title":"J Biol Regul Homeost Agents"},{"key":"10.1016\/j.joms.2024.01.001_bib4","first-page":"2662","article-title":"Treatment of medication-related osteonecrosis of the jaw (MRONJ). A systematic review","volume":"25","author":"Goker","year":"2021","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"10.1016\/j.joms.2024.01.001_bib5","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/jbmr.2405","article-title":"Diagnosis and management of osteonecrosis of the jaw: A systematic review and international consensus","volume":"30","author":"Khan","year":"2015","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.joms.2024.01.001_bib6","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.joms.2009.01.006","article-title":"The role of surgical resection in the management of bisphosphonate-related osteonecrosis of the jaws","volume":"67","author":"Carlson","year":"2009","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.joms.2024.01.001_bib7","article-title":"Mandibular reconstruction with free fibula flap for medication-related osteonecrosis of the jaw in patients with multiple Myeloma","volume":"8","author":"Kaoutzanis","year":"2020","journal-title":"Plast Reconstr Surg Glob Open"},{"key":"10.1016\/j.joms.2024.01.001_bib8","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.ejso.2008.05.002","article-title":"Vascularized fibula flap reconstruction of the mandible in bisphosphonate-related osteonecrosis","volume":"35","author":"Nocini","year":"2009","journal-title":"Eur J Surg Oncol"},{"key":"10.1016\/j.joms.2024.01.001_bib9","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.coms.2019.03.002","article-title":"Fibular reconstruction of the maxilla and mandible with immediate implant-supported prosthetic rehabilitation: Jaw in a Day","volume":"31","author":"Patel","year":"2019","journal-title":"Oral Maxillofac Surg Clin North Am"},{"key":"10.1016\/j.joms.2024.01.001_bib10","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1007\/s00428-007-0516-2","article-title":"Actinomycosis of the jaws--histopathological study of 45 patients shows significant involvement in bisphosphonate-associated osteonecrosis and infected osteoradionecrosis","volume":"451","author":"Hansen","year":"2007","journal-title":"Virchows Arch"},{"key":"10.1016\/j.joms.2024.01.001_bib11","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/S0140-6736(04)16727-5","article-title":"Osteomyelitis","volume":"364","author":"Lew","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.joms.2024.01.001_bib12","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.ijom.2011.12.016","article-title":"Suppurative osteomyelitis, bisphosphonate induced osteonecrosis, osteoradionecrosis: A blinded histopathologic comparison and its implications for the mechanism of each disease","volume":"41","author":"Marx","year":"2012","journal-title":"Int J Oral Maxillofac Surg"},{"key":"10.1016\/j.joms.2024.01.001_bib13","doi-asserted-by":"crossref","first-page":"2026","DOI":"10.1016\/j.jcms.2015.03.006","article-title":"Outcomes of microvascular free flap reconstruction for mandibular osteoradionecrosis: A systematic review","volume":"43","author":"Lee","year":"2015","journal-title":"J Craniomaxillofac Surg"},{"key":"10.1016\/j.joms.2024.01.001_bib14","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1016\/j.bjoms.2020.11.013","article-title":"Outcomes of microvascular composite reconstruction for mandibular osteoradionecrosis","volume":"59","author":"O'Connell","year":"2021","journal-title":"Br J Oral Maxillofac Surg"},{"key":"10.1016\/j.joms.2024.01.001_bib15","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1002\/hed.27024","article-title":"Outcomes after definitive surgery for mandibular osteoradionecrosis","volume":"44","author":"Contrera","year":"2022","journal-title":"Head Neck"},{"key":"10.1016\/j.joms.2024.01.001_bib16","first-page":"258","article-title":"Systemic antibiotic treatment of chronic osteomyelitis in adults","volume":"23","author":"Fantoni","year":"2019","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"10.1016\/j.joms.2024.01.001_bib17","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1067\/moe.2001.117810","article-title":"Treatment of chronic osteomyelitis in Korea","volume":"92","author":"Kim","year":"2001","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.joms.2024.01.001_bib18","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/s40842-020-00096-2","article-title":"Making the equivocal unequivocal: Standardization of clean margins in diabetic foot osteomyelitis","volume":"6","author":"Schmidt","year":"2020","journal-title":"Clin Diabetes Endocrinol"},{"key":"10.1016\/j.joms.2024.01.001_bib19","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.coms.2018.12.005","article-title":"Maxillofacial reconstruction using vascularized fibula free flaps and Endosseous implants","volume":"31","author":"Patel","year":"2019","journal-title":"Oral Maxillofac Surg Clin North Am"},{"key":"10.1016\/j.joms.2024.01.001_bib20","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1016\/j.bjps.2016.05.003","article-title":"A systematic review of functional outcome and quality of life following reconstruction of maxillofacial defects using vascularized free fibula flaps and dental rehabilitation reveals poor data quality","volume":"69","author":"Wijbenga","year":"2016","journal-title":"J Plast Reconstr Aesthet Surg"},{"key":"10.1016\/j.joms.2024.01.001_bib21","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/j.coms.2017.03.007","article-title":"Bone margin analysis for osteonecrosis and osteomyelitis of the jaws","volume":"29","author":"Qaisi","year":"2017","journal-title":"Oral Maxillofac Surg Clin North Am"},{"key":"10.1016\/j.joms.2024.01.001_bib22","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1177\/107327480801500102","article-title":"Practical issues of intraoperative frozen section diagnosis of bone and soft tissue lesions","volume":"15","author":"Bui","year":"2008","journal-title":"Cancer Control"},{"key":"10.1016\/j.joms.2024.01.001_bib23","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.ijom.2022.07.010","article-title":"Intraoperative evaluation of the resected bone margin in mandibular cancers using a trephine drill and frozen section analysis","volume":"52","author":"Hegde","year":"2023","journal-title":"Int J Oral Maxillofac Surg"},{"key":"10.1016\/j.joms.2024.01.001_bib24","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.otohns.2005.09.007","article-title":"Intraoperative evaluation of cortical bony margins with frozen-section analysis","volume":"134","author":"Oxford","year":"2006","journal-title":"Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.joms.2024.01.001_bib25","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.joms.2010.07.014","article-title":"Fluorescence-guided bone resection in bisphosphonate-related osteonecrosis of the jaws: First clinical results of a prospective pilot study","volume":"69","author":"Pautke","year":"2011","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.joms.2024.01.001_bib26","doi-asserted-by":"crossref","first-page":"944","DOI":"10.3390\/antibiotics12060944","article-title":"Systemic Antimicrobial treatment of chronic osteomyelitis in adults: A Narrative review","volume":"12","author":"Besal","year":"2023","journal-title":"Antibiotics (Basel)"},{"key":"10.1016\/j.joms.2024.01.001_bib27","doi-asserted-by":"crossref","DOI":"10.1111\/dme.15162","article-title":"Residual osteomyelitis at the resection margin after conservative surgery is not associated with the recurrence of diabetic foot infection and may successfully be treated without postoperative antibiotic therapy","volume":"40","author":"Aragon-Sanchez","year":"2023","journal-title":"Diabet Med"}],"container-title":["Journal of Oral and Maxillofacial Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278239124000016?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278239124000016?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T17:09:04Z","timestamp":1759511344000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0278239124000016"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":27,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["S0278239124000016"],"URL":"https:\/\/doi.org\/10.1016\/j.joms.2024.01.001","relation":{},"ISSN":["0278-2391"],"issn-type":[{"value":"0278-2391","type":"print"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Risk Factors for Infection Recurrence After Surgical Resection of Advanced Stage Osteonecrosis of the Mandible","name":"articletitle","label":"Article Title"},{"value":"Journal of Oral and Maxillofacial Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.joms.2024.01.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 American Association of Oral and Maxillofacial Surgeons","name":"copyright","label":"Copyright"}]}}