{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T21:25:57Z","timestamp":1767993957736,"version":"3.49.0"},"reference-count":38,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","jopan.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of PeriAnesthesia Nursing"],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1016\/j.jopan.2024.10.010","type":"journal-article","created":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T16:14:03Z","timestamp":1737648843000},"page":"938-944","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Efficacy of Chewing Xylitol Gum on Restoring Postoperative Bowel Activity After Laparoscopic Cholecystectomy: A Three-arm Randomized Controlled Trial"],"prefix":"10.1016","volume":"40","author":[{"given":"Esra","family":"\u00d6ZKAN","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tuna","family":"ALBAYRAK","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jopan.2024.10.010_bib1","first-page":"79","article-title":"Mi\u0307ni\u0307mal invazi\u0307v cerrahi\u0307de g\u00fcncel yakla\u015f\u0131mlar","volume":"3","author":"G\u00fcl","year":"2022","journal-title":"Sel\u00e7uk Sa\u011fl\u0131k Derg"},{"issue":"1","key":"10.1016\/j.jopan.2024.10.010_bib2","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1007\/s00464-019-06739-5","article-title":"Long-term follow-up after single-incision laparoscopic surgery","volume":"34","author":"Barutcu","year":"2020","journal-title":"Surg Endosc"},{"issue":"3","key":"10.1016\/j.jopan.2024.10.010_bib3","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1007\/s00464-016-5134-0","article-title":"A retrospective comparison of robotic cholecystectomy versus laparoscopic cholecystectomy: operative outcomes and cost analysis","volume":"31","author":"Strosberg","year":"2017","journal-title":"Surg Endosc"},{"issue":"2","key":"10.1016\/j.jopan.2024.10.010_bib4","first-page":"336","article-title":"Pain management after laparoscopic cholecystectomy","volume":"5","author":"Yaprak","year":"2019","journal-title":"Akdeniz Med J"},{"issue":"1","key":"10.1016\/j.jopan.2024.10.010_bib5","first-page":"37","article-title":"Laparoskopik kolesistektomi sonras\u0131 geli\u015fen enfeksiyonlar ile ili\u015fkili fakt\u00f6rlerin ve hem\u015firelik tan\u0131lar\u0131n\u0131n belirlenmesi [Determination of nursing diagnoses and factors associated with infections after laparoscopic cholecystectomy]","volume":"5","author":"Ilkaz","year":"2023","journal-title":"Univ Health Sci J Nurs"},{"issue":"7","key":"10.1016\/j.jopan.2024.10.010_bib6","doi-asserted-by":"crossref","first-page":"343","DOI":"10.4236\/ss.2022.137043","article-title":"Iatrogenic bile duct injuries after cholecystectomy, is the laparoscopic approach a good idea?","volume":"13","author":"Tinoco","year":"2022","journal-title":"Surg Sci"},{"issue":"1","key":"10.1016\/j.jopan.2024.10.010_bib7","doi-asserted-by":"crossref","first-page":"26","DOI":"10.5455\/umj.20190130080233","article-title":"The effectiveness of bupivacaine instillation on postoperative pain after elective laparoscopic cholecystectomy: a prospective randomized controlled trial","volume":"5","author":"Arshad","year":"2019","journal-title":"Ulutas Med J"},{"issue":"7","key":"10.1016\/j.jopan.2024.10.010_bib8","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1002\/bjs.10781","article-title":"Postoperative ileus following major colorectal surgery","volume":"105","author":"Chapman","year":"2018","journal-title":"Br J Surg"},{"issue":"43","key":"10.1016\/j.jopan.2024.10.010_bib9","doi-asserted-by":"crossref","first-page":"70066","DOI":"10.18632\/oncotarget.11735","article-title":"Meta-analysis comparing chewing gum versus standard postoperative care after colorectal resection","volume":"7","author":"Song","year":"2016","journal-title":"Oncotarget"},{"issue":"5","key":"10.1016\/j.jopan.2024.10.010_bib10","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1007\/s12262-020-02628-7","article-title":"Effects of gum chewing on early postoperative recovery after laparoscopic cholecystectomy surgery: a randomized controlled trial","volume":"83","author":"Urcanoglu","year":"2021","journal-title":"Indian J Surg"},{"key":"10.1016\/j.jopan.2024.10.010_bib11","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.ygyno.2023.04.009","article-title":"Enhanced recovery after surgery (ERAS\u00ae) society guidelines for gynecologic oncology: addressing implementation challenges - 2023 update","volume":"173","author":"Nelson","year":"2023","journal-title":"Gynecol Oncol"},{"issue":"5","key":"10.1016\/j.jopan.2024.10.010_bib12","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1093\/bja\/78.5.606","article-title":"Multimodal approach to control postoperative pathophysiology and rehabilitation","volume":"78","author":"Kehlet","year":"1997","journal-title":"Br J Anaesth"},{"issue":"3","key":"10.1016\/j.jopan.2024.10.010_bib13","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1097\/NT.0000000000000541","article-title":"Nutrition care process of surgical patients in the context of enhanced recovery after surgery","volume":"57","author":"Khalooeifard","year":"2022","journal-title":"Nutr Today"},{"issue":"3","key":"10.1016\/j.jopan.2024.10.010_bib14","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.clnu.2005.02.003","article-title":"A comparison in five European Centres of case mix, clinical management and outcomes following either conventional or fast-track perioperative care in colorectal surgery","volume":"24","author":"Nygren","year":"2005","journal-title":"Clin Nutr"},{"issue":"2","key":"10.1016\/j.jopan.2024.10.010_bib15","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.ygyno.2015.12.019","article-title":"Guidelines for postoperative care in gynecologic\/oncology surgery: Enhanced Recovery After Surgery (ERAS\u00ae) Society recommendations\u2014Part II","volume":"140","author":"Nelson","year":"2016","journal-title":"Gynecol Oncol"},{"issue":"1","key":"10.1016\/j.jopan.2024.10.010_bib16","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.aorn.2015.04.021","article-title":"Postoperative care of patients undergoing same-day laparoscopic cholecystectomy","volume":"102","author":"Brenner","year":"2015","journal-title":"AORN J"},{"issue":"10","key":"10.1016\/j.jopan.2024.10.010_bib17","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1111\/j.1471-0528.2009.02225.x","article-title":"Gum chewing stimulates early return of bowel motility after caesarean section","volume":"116","author":"Abd-El-Maeboud","year":"2009","journal-title":"BJOG Int J Obstet Gynaecol"},{"issue":"4","key":"10.1016\/j.jopan.2024.10.010_bib18","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1097\/SLE.0000000000000174","article-title":"Xylitol gum chewing to achieve early postoperative restoration of bowel motility after laparoscopic surgery","volume":"25","author":"Gong","year":"2015","journal-title":"Surg Laparosc Endosc Percutan Tech"},{"issue":"1","key":"10.1016\/j.jopan.2024.10.010_bib19","first-page":"53","article-title":"Chewing xylitol gum could accelerate bowel motility recovery after elective open proctectomy for rectal cancer","volume":"70","author":"Yang","year":"2018","journal-title":"Rev Invest Clin"},{"key":"10.1016\/j.jopan.2024.10.010_bib20","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.ijsu.2016.11.088","article-title":"Do we really need the full compliance with ERAS protocol in laparoscopic colorectal surgery? A prospective cohort study","volume":"36","author":"Pisarska","year":"2016","journal-title":"Int J Surg"},{"key":"10.1016\/j.jopan.2024.10.010_bib21","first-page":"788","article-title":"Meta-analysis of randomized studies evaluating chewing gum to enhance postoperative recovery following colectomy","volume":"143","author":"Purkayastha","year":"2008"},{"key":"10.1016\/j.jopan.2024.10.010_bib22","first-page":"1058","article-title":"Efficacy of gum chewing on bowel movement after","volume":"11","author":"Matsuoka","year":"2015","journal-title":"Dis Colon Rectum"},{"issue":"13","key":"10.1016\/j.jopan.2024.10.010_bib23","first-page":"1","article-title":"Influence of gum-chewing on postoperative bowel activity after laparoscopic surgery for gastric cancer: a randomized controlled trial","volume":"96","author":"Ge","year":"2017","journal-title":"Medicine (United States)"},{"issue":"10","key":"10.1016\/j.jopan.2024.10.010_bib24","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.jmig.2023.06.015","article-title":"The effect of postoperative gum chewing on gastrointestinal function following laparoscopic gynecological surgery. a meta-analysis of randomized controlled trials","volume":"30","author":"Douligeris","year":"2023","journal-title":"J Minim Invasive Gynecol"},{"issue":"5","key":"10.1016\/j.jopan.2024.10.010_bib25","article-title":"Effects of gum chewing on recovery from postoperative ileus: a randomized clinical trail","volume":"30","author":"Hsu","year":"2022","journal-title":"J Nurs Res"},{"issue":"5","key":"10.1016\/j.jopan.2024.10.010_bib26","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1080\/01443615.2019.1652891","article-title":"The impact of chewing gum on postoperative bowel activity and postoperative pain after total laparoscopic hysterectomy","volume":"40","author":"Turkay","year":"2020","journal-title":"J Obstet Gynaecol"},{"issue":"17","key":"10.1016\/j.jopan.2024.10.010_bib27","doi-asserted-by":"crossref","first-page":"7225","DOI":"10.1007\/s00253-020-10708-7","article-title":"Health benefits of xylitol","volume":"104","author":"Gasmi Benahmed","year":"2020","journal-title":"Appl Microbiol Biotechnol"},{"issue":"4","key":"10.1016\/j.jopan.2024.10.010_bib28","first-page":"231","article-title":"Sugar alcohol: a comparison of xylitol and sorbitol in food application","volume":"1","author":"Asasta","year":"2024","journal-title":"J Glob Ilm"},{"issue":"1","key":"10.1016\/j.jopan.2024.10.010_bib29","doi-asserted-by":"crossref","first-page":"63","DOI":"10.7212\/zkufbd.v4i1.125","article-title":"Some alternative sweeteners (xylitol, sorbitol, sucralose and stevia): review","volume":"4","author":"Sheet","year":"2014","journal-title":"Karaelmas Sci Eng J"},{"issue":"2","key":"10.1016\/j.jopan.2024.10.010_bib30","doi-asserted-by":"crossref","first-page":"175","DOI":"10.3758\/BF03193146","article-title":"G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences","volume":"39","author":"Faul","year":"2007","journal-title":"Behav Res Methods"},{"issue":"1","key":"10.1016\/j.jopan.2024.10.010_bib31","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.mehy.2008.06.044","article-title":"Hypothesis: hexitols in chewing gum may play a role in reducing postoperative ileus","volume":"72","author":"Tandeter","year":"2009","journal-title":"Med Hypotheses"},{"issue":"2","key":"10.1016\/j.jopan.2024.10.010_bib32","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1177\/1099800415592966","article-title":"The role of xylitol gum chewing in restoring postoperative bowel activity after cesarean section","volume":"18","author":"Lee","year":"2016","journal-title":"Biol Res Nurs"},{"issue":"11","key":"10.1016\/j.jopan.2024.10.010_bib33","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1002\/bjs.10277","article-title":"Randomized clinical trial of chewing gum after laparoscopic colorectal resection","volume":"103","author":"Shum","year":"2016","journal-title":"Br J Surg"},{"issue":"4","key":"10.1016\/j.jopan.2024.10.010_bib34","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1097\/SLE.0000000000000174","article-title":"Xylitol gum chewing to achieve early postoperative restoration of bowel motility after laparoscopic surgery","volume":"25","author":"Gong","year":"2015","journal-title":"Surg Laparosc Endosc Percutan Tech"},{"issue":"5","key":"10.1016\/j.jopan.2024.10.010_bib35","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1080\/01443615.2021.1941821","article-title":"The effect of chewing gum on bowel function postoperatively in patients with total laparoscopic hysterectomy: a randomised controlled trial","volume":"42","author":"Kadirogullari","year":"2022","journal-title":"J Obstet Gynaecol"},{"issue":"9","key":"10.1016\/j.jopan.2024.10.010_bib36","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.bjae.2020.04.006","article-title":"Anaesthesia, analgesia, and the surgical stress response","volume":"20","author":"Cusack","year":"2020","journal-title":"BJA Educ"},{"issue":"7","key":"10.1016\/j.jopan.2024.10.010_bib37","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1007\/s00268-008-9491-2","article-title":"Prolonged postoperative ileus\u2014definition, risk factors, and predictors after surgery","volume":"32","author":"Artinyan","year":"2008","journal-title":"World J Surg"},{"issue":"1","key":"10.1016\/j.jopan.2024.10.010_bib38","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1111\/ajco.12113","article-title":"Gum chewing promotes bowel motility after a radical retropubic prostatectomy","volume":"10","author":"Choi","year":"2014","journal-title":"Asia-Pac J Clin Oncol"}],"container-title":["Journal of PeriAnesthesia Nursing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1089947224005185?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1089947224005185?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T09:35:31Z","timestamp":1753868131000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1089947224005185"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":38,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["S1089947224005185"],"URL":"https:\/\/doi.org\/10.1016\/j.jopan.2024.10.010","relation":{},"ISSN":["1089-9472"],"issn-type":[{"value":"1089-9472","type":"print"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Efficacy of Chewing Xylitol Gum on Restoring Postoperative Bowel Activity After Laparoscopic Cholecystectomy: A Three-arm Randomized Controlled Trial","name":"articletitle","label":"Article Title"},{"value":"Journal of PeriAnesthesia Nursing","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jopan.2024.10.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 American Society of PeriAnesthesia Nurses. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}