{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T19:46:28Z","timestamp":1791575188350,"version":"4.3.4"},"reference-count":24,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","jopan.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of PeriAnesthesia Nursing"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.jopan.2025.07.019","type":"journal-article","created":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T22:02:51Z","timestamp":1763416971000},"page":"410-415","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Comparison of Sedation Efficacy Between Propofol-ketamine and Propofol-fentanyl Combinations in Short Gynecological Procedures"],"prefix":"10.1016","volume":"41","author":[{"given":"Ilke","family":"Tamdogan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet","family":"Degermenci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bilge","family":"Olgun Keles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmut Sami","family":"Tutar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.jopan.2025.07.019_bib1","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1213\/00000539-199711000-00012","article-title":"The changing role of monitored anesthesia care in the ambulatory setting","volume":"85","author":"S\u00e1 R\u00eago","year":"1997","journal-title":"Anesth Analg"},{"issue":"2","key":"10.1016\/j.jopan.2025.07.019_bib2","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1213\/00000539-199408000-00020","article-title":"Propofol infusion during regional anesthesia: sedative, amnestic, and anxiolytic properties","volume":"79","author":"Smith","year":"1994","journal-title":"Anesth Analg"},{"issue":"4","key":"10.1016\/j.jopan.2025.07.019_bib3","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1097\/00000542-199410000-00028","article-title":"Propofol: an update on its clinical use","volume":"81","author":"Smith","year":"1994","journal-title":"Anesthesiology"},{"issue":"4","key":"10.1016\/j.jopan.2025.07.019_bib4","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1097\/00000542-199410000-00008","article-title":"The interaction of fentanyl on the Cp50 of propofol for loss of consciousness and skin incision","volume":"81","author":"Smith","year":"1994","journal-title":"Anesthesiology"},{"issue":"2","key":"10.1016\/j.jopan.2025.07.019_bib5","first-page":"317","article-title":"Propofol versus propofol-ketamine sedation for retrobulbar nerve block: comparison of sedation quality, intraocular pressure changes, and recovery profiles","volume":"89","author":"Frey","year":"1999","journal-title":"Anesth Analg"},{"issue":"4","key":"10.1016\/j.jopan.2025.07.019_bib6","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1213\/00000539-200004000-00016","article-title":"The use of a ketamine-propofol combination during monitored anesthesia care","volume":"90","author":"Badrinath","year":"2000","journal-title":"Anesth Analg"},{"issue":"3","key":"10.1016\/j.jopan.2025.07.019_bib7","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/j.ajem.2015.12.074","article-title":"Ketamine-propofol combination (ketofol) vs. propofol for procedural sedation and analgesia: systematic review and meta-analysis","volume":"34","author":"Jalili","year":"2016","journal-title":"Am J Emerg Med"},{"issue":"1","key":"10.1016\/j.jopan.2025.07.019_bib8","doi-asserted-by":"crossref","first-page":"43","DOI":"10.4097\/kjae.2018.71.1.43","article-title":"Comparison of propofol alone and in combination with ketamine or fentanyl for sedation in endoscopic ultrasonography","volume":"71","author":"Singh","year":"2018","journal-title":"Korean J Anesth"},{"issue":"9","key":"10.1016\/j.jopan.2025.07.019_bib9","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1111\/acem.12737","article-title":"Ketamine-Propofol versus propofol alone for procedural sedation in the emergency department: a systematic review and meta-analysis","volume":"22","author":"Yan","year":"2015","journal-title":"Acad Emerg Med"},{"issue":"1","key":"10.1016\/j.jopan.2025.07.019_bib10","doi-asserted-by":"crossref","first-page":"5","DOI":"10.15171\/apb.2019.002","article-title":"Using ketamine and propofol for procedural sedation of adults in the emergency department: a systematic review and meta-analysis","volume":"9","author":"Ghojazadeh","year":"2019","journal-title":"Adv Pharm Bull"},{"key":"10.1016\/j.jopan.2025.07.019_bib11","doi-asserted-by":"crossref","first-page":"134","DOI":"10.4103\/abr.abr_85_18","article-title":"Comparison of propofol and ketamine combination (Ketofol) and propofol and fentanyl combination (fenofol) on quality of sedation and analgesia in the lumpectomy: a randomized clinical trial","volume":"7","author":"Nazemroaya","year":"2018","journal-title":"Adv Biomed Res"},{"issue":"4","key":"10.1016\/j.jopan.2025.07.019_bib12","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1213\/00000539-200004000-00016","article-title":"Theuse of a ketamine-propofol combination during monitored anesthesia care","volume":"90","author":"Badrinath","year":"2000","journal-title":"Anesth Analg"},{"issue":"6","key":"10.1016\/j.jopan.2025.07.019_bib13","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/j.annemergmed.2012.01.017","article-title":"Ketamine-propofol combination (ketofol) versus propofol alone for emergency department procedural sedation and analgesia: a randomized double-blind trial","volume":"59","author":"Andolfatto","year":"2012","journal-title":"Ann Emerg Med"},{"issue":"9","key":"10.1016\/j.jopan.2025.07.019_bib14","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1016\/j.ajem.2007.12.005","article-title":"Adverse events associated with ketamine for procedural sedation in adults","volume":"26","author":"Strayer","year":"2008","journal-title":"Am J Emerg Med"},{"issue":"4","key":"10.1016\/j.jopan.2025.07.019_bib15","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1213\/ANE.0000000000004967","article-title":"Safety and efficacy of the combination of propofol and ketamine for procedural sedation\/anesthesia in the pediatric population: a systematic review and meta-analysis","volume":"132","author":"Hayes","year":"2021","journal-title":"Anesth Analg"},{"issue":"1","key":"10.1016\/j.jopan.2025.07.019_bib16","first-page":"21393","article-title":"Procedural sedation using two different proportions of ketamine-propofol combination in short gynecological procedures: a randomized controlled trial","volume":"14","author":"Padhi","year":"2022","journal-title":"Cureus"},{"issue":"3","key":"10.1016\/j.jopan.2025.07.019_bib17","first-page":"217","article-title":"Comparision of ketofol and midazolam-fentanyl sedoanalgesia methods in septoplasty operations","volume":"31","author":"Kele\u015f","year":"2023","journal-title":"JARSS"},{"issue":"2","key":"10.1016\/j.jopan.2025.07.019_bib18","doi-asserted-by":"crossref","first-page":"72","DOI":"10.4103\/1658-354X.65132","article-title":"Comparison of two drug combinations in total intravenous anesthesia: propofol-ketamine and propofol-fentanyl","volume":"4","author":"Bajwa","year":"2010","journal-title":"Saudi J Anaesth"},{"issue":"1","key":"10.1016\/j.jopan.2025.07.019_bib19","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1186\/s12890-023-02517-1","article-title":"Comparison of remifentanil and esketamine in combination with propofol for patient sedation during fiberoptic bronchoscopy","volume":"23","author":"Nie","year":"2023","journal-title":"BMC Pulm Med"},{"issue":"1","key":"10.1016\/j.jopan.2025.07.019_bib20","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1097\/TA.0b013e318250cdb8","article-title":"Ketamine\/propofol ad mixture (ketofol) is associated with improved hemodynamics as an induction agent: a randomized, controlled trial","volume":"73","author":"Smischney","year":"2012","journal-title":"J Trauma Acute Care Surg"},{"issue":"5","key":"10.1016\/j.jopan.2025.07.019_bib21","first-page":"1","article-title":"Comparison of propofol and ketamine versus propofol and fentanyl for puerperal sterilization, a randomized clinical trial","volume":"8","author":"Kb","year":"2014","journal-title":"J Clin Diagn Res"},{"issue":"1","key":"10.1016\/j.jopan.2025.07.019_bib22","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1186\/s12871-023-02292-w","article-title":"Comparison of different ratios of propofol-ketamine admixture in rapid-sequence induction of anesthesia for emergency laparotomy: a randomized controlled trial","volume":"23","author":"Elsherbiny","year":"2023","journal-title":"BMC Anesthesiol"},{"key":"10.1016\/j.jopan.2025.07.019_bib23","first-page":"33","article-title":"Comparison of hemodynamic stability of propofol ketamine versus etomidate ketamine during induction in peritonitis cases posted for emergency surgery","volume":"2","author":"Suneetha","year":"2023","journal-title":"EUREKA\u00a0Health Sci"},{"issue":"2","key":"10.1016\/j.jopan.2025.07.019_bib24","doi-asserted-by":"crossref","first-page":"72","DOI":"10.4103\/1658-354X.65132","article-title":"Comparison of two\u00a0drug combinations in total intravenous anesthesia: propofol-ketamine and propofol-fentanyl","volume":"4","author":"Bajwa","year":"2010","journal-title":"Saudi J Anaesth"}],"container-title":["Journal of PeriAnesthesia Nursing"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1089947225004149?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1089947225004149?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T23:11:37Z","timestamp":1775517097000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1089947225004149"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["S1089947225004149"],"URL":"https:\/\/doi.org\/10.1016\/j.jopan.2025.07.019","relation":{},"ISSN":["1089-9472"],"issn-type":[{"value":"1089-9472","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparison of Sedation Efficacy Between Propofol-ketamine and Propofol-fentanyl Combinations in Short Gynecological Procedures","name":"articletitle","label":"Article Title"},{"value":"Journal of PeriAnesthesia Nursing","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jopan.2025.07.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 American Society of PeriAnesthesia Nurses. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}