{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T14:13:05Z","timestamp":1789135985322,"version":"build-2803163510"},"reference-count":29,"publisher":"Scientific Scholar","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Orthopaedics"],"published-print":{"date-parts":[[2020,7]]},"DOI":"10.1016\/j.jor.2020.01.013","type":"journal-article","created":{"date-parts":[[2020,1,13]],"date-time":"2020-01-13T13:43:23Z","timestamp":1578923003000},"page":"257-260","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Association of catechol-O-methyltranferase 472G>A (Val158Met) polymorphism with susceptibility to fibromyalgia syndrome"],"prefix":"10.25259","volume":"20","author":[{"given":"Maryam","family":"Hatami","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Reza","family":"Sobhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyed Alireza","family":"Dastgheib","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Hossein","family":"Jarahzadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammadali","family":"Jafari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amirhossein","family":"Yadegari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jalal","family":"Sadeghizadeh-Yazdi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hossein","family":"Neamatzadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","reference":[{"issue":"2","key":"10.1016\/j.jor.2020.01.013_bib1","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1007\/s00296-010-1678-9","article-title":"Candidate gene studies of fibromyalgia: a systematic review and meta-analysis","volume":"32","author":"Lee","year":"2012","journal-title":"Rheumatol Int"},{"issue":"7","key":"10.1016\/j.jor.2020.01.013_bib2","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1007\/s00296-008-0525-8","article-title":"Polymorphisms of the serotonin-2A receptor and catechol-O-methyltransferase genes: a study on fibromyalgia susceptibility","volume":"28","author":"Tander","year":"2008","journal-title":"Rheumatol Int"},{"issue":"4","key":"10.1016\/j.jor.2020.01.013_bib4","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.rbr.2016.10.004","article-title":"Prevalence of fibromyalgia: literature review update","volume":"57","author":"Marques","year":"2017","journal-title":"Rev Bras Reumatol"},{"issue":"10","key":"10.1016\/j.jor.2020.01.013_bib5","doi-asserted-by":"crossref","first-page":"952","DOI":"10.3109\/00498254.2014.913083","article-title":"Clinical symptoms in fibromyalgia are associated to catechol -O- methyltransferase (COMT) gene Val158Met polymorphism","volume":"44","author":"Inanir","year":"2014","journal-title":"Xenobiotica"},{"key":"10.1016\/j.jor.2020.01.013_bib6","author":"Cohen"},{"issue":"6","key":"10.1016\/j.jor.2020.01.013_bib7","doi-asserted-by":"crossref","first-page":"984","DOI":"10.3904\/kjim.2016.207","article-title":"New insights into the genetics of fibromyalgia","volume":"32","author":"Park","year":"2017","journal-title":"Korean J Intern Med"},{"issue":"3","key":"10.1016\/j.jor.2020.01.013_bib8","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1186\/ar1950","article-title":"Biology and therapy of fibromyalgia: pain in fibromyalgia syndrome","volume":"8","author":"Staud","year":"2006","journal-title":"Arthritis Res Ther"},{"issue":"4","key":"10.1016\/j.jor.2020.01.013_bib9","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/s11916-016-0556-x","article-title":"Fibromyalgia pathogenesis and treatment options update","volume":"20","author":"Chinn","year":"2016","journal-title":"Curr Pain Headache Rep"},{"issue":"6","key":"10.1016\/j.jor.2020.01.013_bib10","doi-asserted-by":"crossref","first-page":"984","DOI":"10.3904\/kjim.2016.207","article-title":"New insights into the genetics of fibromyalgia","volume":"32","author":"Park","year":"2017","journal-title":"Korean J Intern Med"},{"issue":"6","key":"10.1016\/j.jor.2020.01.013_bib11","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.3390\/ijms19061707","article-title":"The role of genetic polymorphisms in chronic pain patients","volume":"19","author":"Knezevic","year":"2018","journal-title":"Int J Mol Sci"},{"issue":"2","key":"10.1016\/j.jor.2020.01.013_bib12","article-title":"Association between catechol-O-methyltransferase Val158Met (158G\/A) polymorphism and suicide susceptibility: a meta-analysis","volume":"17","author":"Sadeghiyeh","year":"2017","journal-title":"J Res Health Sci"},{"issue":"2","key":"10.1016\/j.jor.2020.01.013_bib13","article-title":"Association between catechol-O-methyltransferase Val158Met (158G\/A) polymorphism and suicide susceptibility: a meta-analysis","volume":"17","author":"Sadeghiyeh","year":"2017","journal-title":"J Res Health Sci"},{"issue":"1","key":"10.1016\/j.jor.2020.01.013_bib14","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s00296-014-3075-2","article-title":"Association between the COMT Val158Met polymorphism and fibromyalgia susceptibility and fibromyalgia impact questionnaire score: a meta-analysis","volume":"35","author":"Lee","year":"2015","journal-title":"Rheumatol Int"},{"issue":"6","key":"10.1016\/j.jor.2020.01.013_bib15","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1093\/carcin\/bgh080","article-title":"Genetic polymorphisms of MPO, COMT, MnSOD, NQO1, interactions with environmental exposures and bladder cancer risk","volume":"25","author":"Hung","year":"2004","journal-title":"Carcinogenesis"},{"issue":"12","key":"10.1016\/j.jor.2020.01.013_bib16","first-page":"8489","article-title":"Meta-analysis reveals a lack of association between a common catechol-O-methyltransferase (COMT) polymorphism val158met and fibromyalgia","volume":"7","author":"Zhang","year":"2014","journal-title":"Int J Clin Exp Pathol"},{"issue":"10","key":"10.1016\/j.jor.2020.01.013_bib17","doi-asserted-by":"crossref","first-page":"952","DOI":"10.3109\/00498254.2014.913083","article-title":"Clinical symptoms in fibromyalgia are associated to catechol -O- methyltransferase (COMT) gene Val158Met polymorphism","volume":"44","author":"Inanir","year":"2014","journal-title":"Xenobiotica"},{"issue":"7","key":"10.1016\/j.jor.2020.01.013_bib18","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1002\/ejp.837","article-title":"Association between catechol-O-methyl transferase gene polymorphisms and fibromyalgia in a Korean population: a case-control study","volume":"20","author":"Park","year":"2016","journal-title":"Eur J Pain"},{"issue":"1","key":"10.1016\/j.jor.2020.01.013_bib19","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1002\/j.1532-2149.2012.00153.x","article-title":"Pain sensitivity in fibromyalgia is associated with catechol-O-methyltransferase (COMT) gene","volume":"17","author":"Mart\u00ednez-Jauand","year":"2013","journal-title":"Eur J Pain"},{"issue":"10","key":"10.1016\/j.jor.2020.01.013_bib20","doi-asserted-by":"crossref","first-page":"952","DOI":"10.3109\/00498254.2014.913083","article-title":"Clinical symptoms in fibromyalgia are associated to catechol -O- methyltransferase (COMT) gene Val158Met polymorphism","volume":"44","author":"Inanir","year":"2014","journal-title":"Xenobiotica"},{"issue":"1","key":"10.1016\/j.jor.2020.01.013_bib21","article-title":"The catechol-methyltransferase rs4680 G > A polymorphism is associated with uterine leiomyoma susceptibility","volume":"6","author":"Heydari","year":"2019","journal-title":"Gene, Cell Tissue"},{"issue":"4","key":"10.1016\/j.jor.2020.01.013_bib22","first-page":"265","article-title":"Catechol-O-Methyltransferase (COMT) gene (Val158Met) and brain-derived neurotropic factor (BDNF) (Val66Met) genes polymorphism in schizophrenia: a case-control study","volume":"12","author":"Saravani","year":"2017","journal-title":"Iran J Psychiatry"},{"issue":"1","key":"10.1016\/j.jor.2020.01.013_bib23","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/s00296-014-3075-2","article-title":"Association between the COMT Val158Met polymorphism and fibromyalgia susceptibility and fibromyalgia impact questionnaire score: a meta-analysis","volume":"35","author":"Lee","year":"2015","journal-title":"Rheumatol Int"},{"issue":"12","key":"10.1016\/j.jor.2020.01.013_bib24","first-page":"8489","article-title":"Meta-analysis reveals a lack of association between a common catechol-O-methyltransferase (COMT) polymorphism val158met and fibromyalgia","volume":"7","author":"Zhang","year":"2014","journal-title":"Int J Clin Exp Pathol"},{"issue":"3","key":"10.1016\/j.jor.2020.01.013_bib25","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.pain.2006.09.022","article-title":"Catechol-O-methyltransferase inhibition increases pain sensitivity through activation of both \u03b22- and \u03b23-adrenergic receptors","volume":"128","author":"Nackley","year":"2007","journal-title":"Pain"},{"issue":"8","key":"10.1016\/j.jor.2020.01.013_bib26","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0043423","article-title":"A meta-analysis of the Val158Met COMT polymorphism and violent behavior in schizophrenia","volume":"7","author":"Singh","year":"2012","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.jor.2020.01.013_bib27","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1007\/s00296-017-3896-x","article-title":"The TT genotype of the rs6860 polymorphism of the charged multivesicular body protein 1A gene is associated with susceptibility to fibromyalgia in southern Spanish women","volume":"38","author":"Est\u00e9vez-L\u00f3pez","year":"2018","journal-title":"Rheumatol Int"},{"issue":"2","key":"10.1016\/j.jor.2020.01.013_bib28","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/s00296-010-1659-z","article-title":"Influence of catechol-O-methyltransferase (COMT) gene polymorphisms in pain sensibility of Brazilian fibromialgia patients","volume":"32","author":"Barbosa","year":"2012","journal-title":"Rheumatol Int"},{"issue":"1","key":"10.1016\/j.jor.2020.01.013_bib29","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1002\/j.1532-2149.2012.00153.x","article-title":"Pain sensitivity in fibromyalgia is associated with catechol-O-methyltransferase (COMT) gene","volume":"17","author":"Mart\u00ednez-Jauand","year":"2013","journal-title":"Eur J Pain"},{"issue":"2","key":"10.1016\/j.jor.2020.01.013_bib30","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.jpain.2013.10.004","article-title":"Central pain sensitization, COMT Val158Met polymorphism, and emotional factors in fibromyalgia","volume":"15","author":"Desmeules","year":"2014","journal-title":"J Pain"}],"updated-by":[{"DOI":"10.1016\/j.jor.2020.12.006","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000}}],"container-title":["Journal of Orthopaedics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0972978X20300131?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0972978X20300131?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T14:03:37Z","timestamp":1789135417000},"score":1,"resource":{"primary":{"URL":"https:\/\/jortho.org\/association-of-catechol-o-methyltranferase-472ga-val158met-polymorphism-with-susceptibility-to-fibromyalgia-syndrome\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":29,"alternative-id":["S0972978X20300131"],"URL":"https:\/\/doi.org\/10.1016\/j.jor.2020.01.013","relation":{},"ISSN":["0972-978X"],"issn-type":[{"value":"0972-978X","type":"print"}],"subject":[],"published":{"date-parts":[[2020,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association of catechol-O-methyltranferase 472G>A (Val158Met) polymorphism with susceptibility to fibromyalgia syndrome","name":"articletitle","label":"Article Title"},{"value":"Journal of Orthopaedics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jor.2020.01.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Professor P K Surendran Memorial Education Foundation. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}