{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T16:33:37Z","timestamp":1770741217732,"version":"3.49.0"},"reference-count":79,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Stomatology, Oral and Maxillofacial Surgery"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.jormas.2024.101809","type":"journal-article","created":{"date-parts":[[2024,2,29]],"date-time":"2024-02-29T09:57:21Z","timestamp":1709200641000},"page":"101809","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"S1","title":["A comprehensive consolidation of data on the relationship between IRF6 polymorphisms and non-syndromic cleft lip\/palate susceptibility: From 79 case-control studies"],"prefix":"10.1016","volume":"125","author":[{"given":"Mohammad","family":"Golshan-Tafti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seyed Alireza","family":"Dastgheib","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reza","family":"Bahrami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hossein","family":"Aarafi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elnaz","family":"Foroughi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seyed Reza","family":"Mirjalili","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naeimeh","family":"Kheirandish","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryam","family":"Aghasipour","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amirmasoud","family":"Shiri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sepideh","family":"Azizi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazem","family":"Aghili","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Manzourolhojeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hossein","family":"Neamatzadeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jormas.2024.101809_bib0001","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1080\/15513815.2019.1636430","article-title":"Association of axis inhibition protein 2 polymorphisms with non-syndromic cleft lip with or without cleft palate in Iranian children","volume":"39","author":"Noroozi","year":"2020","journal-title":"Fetal Pediatr Pathol"},{"key":"10.1016\/j.jormas.2024.101809_bib0002","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/15513815.2019.1683918","article-title":"Association of MTHFR 1298A >C polymorphism with susceptibility to non-syndromic cleft lip with or without palate: a case-control study and meta-analysis","volume":"40","author":"Niktabar","year":"2021","journal-title":"Fetal Pediatr Pathol"},{"key":"10.1016\/j.jormas.2024.101809_bib0003","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1080\/15513815.2019.1707918","article-title":"Association of fetal MTHFR 677C >T Polymorphism with non-syndromic cleft lip with or without palate risk: a systematic review and meta-analysis","volume":"40","author":"Amooee","year":"2021","journal-title":"Fetal Pediatr Pathol"},{"key":"10.1016\/j.jormas.2024.101809_bib0004","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.1002\/bdr2.1589","article-title":"National population-based estimates for major birth defects, 2010-2014","volume":"111","author":"Mai","year":"2019","journal-title":"Birth Defects Res"},{"key":"10.1016\/j.jormas.2024.101809_bib0005","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1111\/cga.12276","article-title":"Prevalence of orofacial clefts and risks for nonsyndromic cleft lip with or without cleft palate in newborns at a university hospital from West Mexico","volume":"58","author":"Corona-Rivera","year":"2018","journal-title":"Congenit Anom"},{"key":"10.1016\/j.jormas.2024.101809_bib0006","article-title":"Global, regional and national burden of orofacial clefts from 1990 to 2019: an analysis of the Global Burden of Disease Study 2019","volume":"55","author":"Wang","year":"2023","journal-title":"Ann Med"},{"key":"10.1016\/j.jormas.2024.101809_bib0007","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1080\/15513815.2019.1707916","article-title":"Association of BMP4 rs17563 polymorphism with nonsyndromic cleft lip with or without cleft palate risk: literature review and comprehensive meta-analysis","volume":"40","author":"Bahrami","year":"2021","journal-title":"Fetal Pediatr Pathol"},{"key":"10.1016\/j.jormas.2024.101809_bib0008","first-page":"578","article-title":"Analysis of environmental exposures for nonsyndromic cleft lip and\/or palate: a case-control study","volume":"51","author":"Sakran","year":"2022","journal-title":"Iran J Public Health"},{"key":"10.1016\/j.jormas.2024.101809_bib0009","doi-asserted-by":"crossref","DOI":"10.1016\/j.clinsp.2023.100266","article-title":"Maternal consumption of caffeine and second-hand tobacco smoke as risk factors for the development of oral clefts","volume":"78","author":"de Andrade","year":"2023","journal-title":"Clinics"},{"key":"10.1016\/j.jormas.2024.101809_bib0010","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1038\/s10038-023-01137-1","article-title":"Identification of putative regulatory single-nucleotide variants in NTN1 gene associated with NSCL\/P","volume":"68","author":"Tao","year":"2023","journal-title":"J Hum Genet"},{"key":"10.1016\/j.jormas.2024.101809_bib0011","doi-asserted-by":"crossref","first-page":"3645","DOI":"10.1007\/s00261-022-03625-y","article-title":"Endorectal ultrasound radiomics in locally advanced rectal cancer patients: despeckling and radiotherapy response prediction using machine learning","volume":"47","author":"Abbaspour","year":"2022","journal-title":"Abdom Radiol"},{"key":"10.1016\/j.jormas.2024.101809_bib0012","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2018.00502","article-title":"Six NSCL\/P loci show associations with normal-range craniofacial variation","volume":"9","author":"Indencleef","year":"2018","journal-title":"Front Genet"},{"key":"10.1016\/j.jormas.2024.101809_bib0013","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1007\/s00438-022-01919-w","article-title":"Identification of novel susceptibility genes for non-syndromic cleft lip with or without cleft palate using NGS-based multigene panel testing","volume":"297","author":"D\u0105browska","year":"2022","journal-title":"Mol Genet Genom"},{"key":"10.1016\/j.jormas.2024.101809_bib0014","doi-asserted-by":"crossref","first-page":"14364","DOI":"10.1038\/ncomms14364","article-title":"Genome-wide analyses of non-syndromic cleft lip with palate identify 14 novel loci and genetic heterogeneity","volume":"8","author":"Yu","year":"2017","journal-title":"Nat Commun"},{"key":"10.1016\/j.jormas.2024.101809_bib0015","doi-asserted-by":"crossref","first-page":"104","DOI":"10.52547\/wjps.10.3.104","article-title":"Inferior part of rectus abdominis muscle flap outcomes after abdominoperineal resection: a case series pilot study","volume":"10","author":"Alemrajabi","year":"2021","journal-title":"World J Plast Surg"},{"key":"10.1016\/j.jormas.2024.101809_bib0016","doi-asserted-by":"crossref","first-page":"e03019","DOI":"10.1016\/j.heliyon.2019.e03019","article-title":"Assessment of candidate genes and genetic heterogeneity in human non syndromic orofacial clefts specifically non syndromic cleft lip with or without palate","volume":"5","author":"Saleem","year":"2019","journal-title":"Heliyon"},{"key":"10.1016\/j.jormas.2024.101809_bib0017","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1002\/ajmg.c.31381","article-title":"Genetics of cleft lip and cleft palate","volume":"163C","author":"Leslie","year":"2013","journal-title":"Am J Med Genet C"},{"key":"10.1016\/j.jormas.2024.101809_bib0018","doi-asserted-by":"crossref","DOI":"10.1007\/s12032-015-0493-2","article-title":"Radiation sensitization with sodium nitrite in patients with brain metastases: a pilot randomized controlled trial","volume":"32","author":"Hosseini","year":"2015","journal-title":"Med Oncol"},{"key":"10.1016\/j.jormas.2024.101809_bib0019","doi-asserted-by":"crossref","first-page":"2348","DOI":"10.1093\/hmg\/ddac037","article-title":"Polygenic risk impacts PDGFRA mutation penetrance in non-syndromic cleft lip and palate","volume":"31","author":"Yu","year":"2022","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.jormas.2024.101809_bib0020","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1002\/bdra.23540","article-title":"Association between IRF6 and 8q24 polymorphisms and nonsyndromic cleft lip with or without cleft palate: systematic review and meta-analysis","volume":"106","author":"Wattanawong","year":"2016","journal-title":"Birth Defects Res Part A"},{"key":"10.1016\/j.jormas.2024.101809_bib0021","doi-asserted-by":"crossref","first-page":"3080","DOI":"10.1002\/ajmg.a.35634","article-title":"Three polymorphisms in IRF6 and 8q24 are associated with nonsyndromic cleft lip with or without cleft palate: evidence from 20 studies","volume":"158A","author":"Wang","year":"2012","journal-title":"Am J Med Genet Part A"},{"key":"10.1016\/j.jormas.2024.101809_bib0022","first-page":"14","article-title":"Association of IRF6 rs2235371 polymorphism with non-syndromic cleft lip\/palate: a meta-analysis","volume":"4","author":"Neamatzadeh","year":"2021","journal-title":"World J Peri Neonatol"},{"key":"10.1016\/j.jormas.2024.101809_bib0023","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2020.583115","article-title":"A novel van der Woude syndrome-causing IRF6 variant is subject to incomplete non-sense-mediated mRNA decay affecting the phenotype of keratinocytes","volume":"8","author":"Degen","year":"2020","journal-title":"Front Cell Dev Biol"},{"key":"10.1016\/j.jormas.2024.101809_bib0024","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.archoralbio.2017.09.032","article-title":"Association between the IRF6 rs2235371 polymorphism and the risk of nonsyndromic cleft lip with or without cleft palate in Chinese Han populations: a meta-analysis","volume":"84","author":"Xia","year":"2017","journal-title":"Arch Oral Biol"},{"key":"10.1016\/j.jormas.2024.101809_bib0025","first-page":"393","article-title":"A case of A fractured fragment of tracheostomy tube entering the left bronchus: a case report","volume":"23","author":"Amini","year":"2021","journal-title":"J Babol Univ Med Sci"},{"key":"10.1016\/j.jormas.2024.101809_bib0026","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1038\/ng.242","article-title":"Disruption of an AP-2alpha binding site in an IRF6 enhancer is associated with cleft lip","volume":"40","author":"Rahimov","year":"2008","journal-title":"Nat Genet"},{"key":"10.1016\/j.jormas.2024.101809_bib0027","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1038\/ng.333","article-title":"Key susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 8q24","volume":"41","author":"Birnbaum","year":"2009","journal-title":"Nat Genet"},{"key":"10.1016\/j.jormas.2024.101809_bib0028","first-page":"132","article-title":"IRF6 AP-2a binding site promoter polymorphism is associated with oral clefts in Latvia","volume":"16","author":"Krasone","year":"2014","journal-title":"Stomatologija"},{"key":"10.1016\/j.jormas.2024.101809_bib0029","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1597\/11-220","article-title":"Association and mutation analyses of the IRF6 gene in families with nonsyndromic and syndromic cleft lip and\/or cleft palate","volume":"51","author":"Pegelow","year":"2014","journal-title":"Cleft Palate-Craniofac J"},{"key":"10.1016\/j.jormas.2024.101809_bib0030","doi-asserted-by":"crossref","first-page":"226S","DOI":"10.1177\/0022034515581013","article-title":"IRF6 is a marker of severity in nonsyndromic cleft lip\/palate","volume":"94","author":"Kerameddin","year":"2015","journal-title":"J Dent Res"},{"key":"10.1016\/j.jormas.2024.101809_bib0031","doi-asserted-by":"crossref","first-page":"2344","DOI":"10.1002\/ajmg.a.37181","article-title":"Genetic risk factors for nonsyndromic cleft lip with or without cleft palate in a Brazilian population with high African ancestry","volume":"167","author":"do Rego Borges","year":"2015","journal-title":"Am J Med Genet Part A"},{"key":"10.1016\/j.jormas.2024.101809_bib0032","doi-asserted-by":"crossref","first-page":"152","DOI":"10.5507\/bp.2017.009","article-title":"Polymorphisms at 1q32, 8q24, and 17q22 loci are associated with nonsyndromic cleft lip with or without cleft palate risk in the Slovak population","volume":"161","author":"Salagovic","year":"2017","journal-title":"Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub"},{"key":"10.1016\/j.jormas.2024.101809_bib0033","first-page":"30","article-title":"Association between IRF6 rs642961 polymorphism and nonsyndromic cleft lip with or without cleft palate Risk in an Iranian Population","volume":"1","author":"Niktabar","year":"2018","journal-title":"World J Peri Neonatol"},{"key":"10.1016\/j.jormas.2024.101809_bib0034","article-title":"IRF6 polymorphisms in Brazilian patients with non-syndromic cleft lip with or without palate","author":"Bezerra","year":"2019","journal-title":"Braz J Otorhinolaryngol"},{"key":"10.1016\/j.jormas.2024.101809_bib0035","doi-asserted-by":"crossref","DOI":"10.1089\/gtmb.2018.0315","article-title":"Association between an interferon regulatory factor 6 gene polymorphism and nonsyndromic cleft palate risk","author":"Xing","year":"2019","journal-title":"Genet Test Mol Biomarkers"},{"key":"10.1016\/j.jormas.2024.101809_bib0036","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1002\/gepi.20314","article-title":"Genetic variants in IRF6 and the risk of facial clefts: single-marker and haplotype-based analyses in a population-based case-control study of facial clefts in Norway","volume":"32","author":"Jugessur","year":"2008","journal-title":"Genet Epidemiol"},{"key":"10.1016\/j.jormas.2024.101809_bib0037","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1177\/0022034509341040","article-title":"Association between IRF6 SNPs and oral clefts in West China","volume":"88","author":"Huang","year":"2009","journal-title":"J Dent Res"},{"key":"10.1016\/j.jormas.2024.101809_bib0038","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1002\/bdra.20687","article-title":"Association between genetic variants of reported candidate genes or regions and risk of cleft lip with or without cleft palate in the polish population","volume":"88","author":"Mostowska","year":"2010","journal-title":"Birth Defects Res Part A"},{"key":"10.1016\/j.jormas.2024.101809_bib0039","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1002\/bdra.20639","article-title":"Testing reported associations of genetic risk factors for oral clefts in a large Irish study population","volume":"88","author":"Carter","year":"2010","journal-title":"Birth Defects Res Part A"},{"key":"10.1016\/j.jormas.2024.101809_bib0040","doi-asserted-by":"crossref","first-page":"2422","DOI":"10.1002\/ajmg.a.34191","article-title":"Analysis of genomewide association signals for nonsyndromic cleft lip\/palate in a Kenya African Cohort","volume":"155A","author":"Weatherley-White","year":"2011","journal-title":"Am J Med Genet Part A"},{"key":"10.1016\/j.jormas.2024.101809_bib0041","doi-asserted-by":"crossref","first-page":"e45441","DOI":"10.1371\/journal.pone.0045441","article-title":"Interaction between IRF6 and TGFA genes contribute to the risk of nonsyndromic cleft lip\/palate","volume":"7","author":"Letra","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.jormas.2024.101809_bib0042","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1002\/ajmg.a.35830","article-title":"Polymorphisms at regions 1p22.1 (rs560426) and 8q24 (rs1530300) are risk markers for nonsyndromic cleft lip and\/or palate in the Brazilian population","volume":"161","author":"Bagordakis","year":"2013","journal-title":"Am J Med Genet Part A"},{"key":"10.1016\/j.jormas.2024.101809_bib0043","doi-asserted-by":"crossref","first-page":"e70754","DOI":"10.1371\/journal.pone.0070754","article-title":"TGFA and IRF6 contribute to the risk of nonsyndromic cleft lip with or without cleft palate in northeast China","volume":"8","author":"Lu","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.jormas.2024.101809_bib0044","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.bjoms.2014.12.008","article-title":"Association of single-nucleotide polymorphisms in the IRF6 gene with non-syndromic cleft lip with or without cleft palate in the Xinjiang Uyghur population","volume":"53","author":"Mijiti","year":"2015","journal-title":"Br J Oral Maxillofac Surg"},{"key":"10.1016\/j.jormas.2024.101809_bib0045","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.mgene.2015.02.002","article-title":"IRF6 polymorphisms in Mexican patients with non-syndromic cleft lip","volume":"4","author":"Ibarra-Arce","year":"2015","journal-title":"Meta Gene"},{"key":"10.1016\/j.jormas.2024.101809_bib0046","doi-asserted-by":"crossref","DOI":"10.4238\/gmr.15038210","article-title":"Association of single-nucleotide polymorphisms, rs2235371 and rs2013162, in the IRF6 gene with non-syndromic cleft palate in northeast China","volume":"15","author":"Xu","year":"2016","journal-title":"Genet Mol Res"},{"key":"10.1016\/j.jormas.2024.101809_bib0047","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4172\/2332-0702.1000233","article-title":"Interferon Regulatory Factor 6 (IRF6) and gene \u2013 environment interactions in non-syndromic orofacial cleft cases in saudi arabia-a case control study","volume":"06","author":"Alamoudi","year":"2018","journal-title":"J Oral Hyg Health"},{"key":"10.1016\/j.jormas.2024.101809_bib0048","series-title":"A preliminary investigation into orofacial clefts in the central and western regions of Saudi Arabia","author":"Sabbagh","year":"2015"},{"key":"10.1016\/j.jormas.2024.101809_bib0049","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/j.1601-0825.2009.01627.x","article-title":"Lack of association between IRF6 polymorphisms (rs2235371 and rs642961) and non-syndromic cleft lip and\/or palate in a Brazilian population","volume":"16","author":"Parana\u00edba","year":"2010","journal-title":"Oral Dis"},{"key":"10.1016\/j.jormas.2024.101809_bib0050","first-page":"181","article-title":"Association of rs2013162 and rs2235375 polymorphisms in IRF6 gene with susceptibility to non-syndromic cleft lip and palate","volume":"14","author":"Soleymani","year":"2022","journal-title":"Avicenna J Med Biotechnol"},{"key":"10.1016\/j.jormas.2024.101809_bib0051","doi-asserted-by":"crossref","first-page":"14","DOI":"10.29228\/HMJ.9","article-title":"Investigation of the SNPs of IRF6 gene in non-syndromic cleft lip and\/or palate (NSCLP) in a Turkish population","volume":"2","author":"Ye\u011fin","year":"2022","journal-title":"Hippocrat Med J"},{"key":"10.1016\/j.jormas.2024.101809_bib0052","doi-asserted-by":"crossref","first-page":"1995","DOI":"10.3390\/genes14111995","article-title":"Association between IRF6, TP63, GREM1 gene polymorphisms and non-syndromic orofacial cleft phenotypes in vietnamese population: a case-control and family-based study","volume":"14","author":"Pham","year":"2023","journal-title":"Genes"},{"key":"10.1016\/j.jormas.2024.101809_bib0053","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1056\/NEJMoa032909","article-title":"Interferon regulatory factor 6 (IRF6) gene variants and the risk of isolated cleft lip or palate","volume":"351","author":"Zucchero","year":"2004","journal-title":"New Engl J Med"},{"key":"10.1016\/j.jormas.2024.101809_bib0054","doi-asserted-by":"crossref","first-page":"e46","DOI":"10.1136\/jmg.2005.032235","article-title":"Significant association between IRF6 820G->A and non-syndromic cleft lip with or without cleft palate in the Thai population","volume":"42","author":"Srichomthong","year":"2005","journal-title":"J Med Genet"},{"key":"10.1016\/j.jormas.2024.101809_bib0055","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1089\/gtmb.2008.0115","article-title":"MTHFR 677TT Alone and IRF6 820GG Together with MTHFR 677CT, but Not MTHFR A1298C, are risks for nonsyndromic cleft lip with or without cleft palate in an Indian population","volume":"13","author":"Ali","year":"2009","journal-title":"Genet Test Mol Biomark"},{"key":"10.1016\/j.jormas.2024.101809_bib0056","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1597\/07-131.1","article-title":"Association analysis between the IRF6 G820A polymorphism and nonsyndromic cleft lip and\/or cleft palate in a Chinese population","volume":"46","author":"Tang","year":"2009","journal-title":"Cleft Palate Craniofac J"},{"key":"10.1016\/j.jormas.2024.101809_bib0057","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/S1007-4376(09)60024-1","article-title":"Association of single nucleotide polymorphisms in IRF6 and TGFA genes with nonsyndromic cleft lip with or without cleft palate in Chinese patients","volume":"23","author":"Shen","year":"2009","journal-title":"J Nanjing Med Univ"},{"key":"10.1016\/j.jormas.2024.101809_bib0058","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.3892\/mmr.2013.1617","article-title":"SNPs and interaction analyses of IRF6, MSX1 and PAX9 genes in patients with non\u2011syndromic cleft lip with or without palate","volume":"8","author":"Song","year":"2013","journal-title":"Mol Med Rep"},{"key":"10.1016\/j.jormas.2024.101809_bib0059","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1177\/0974909820140405","article-title":"Association of IRF6 (G820A) gene variant with nonsyndromic cleft lip and palate in South Indian population","volume":"48","author":"Rathore","year":"2014","journal-title":"J Indian Orthod Soc"},{"key":"10.1016\/j.jormas.2024.101809_bib0060","doi-asserted-by":"crossref","first-page":"2505","DOI":"10.1002\/ajmg.a.33624","article-title":"IRF6 polymorphisms are associated with nonsyndromic orofacial clefts in a Chinese Han population","volume":"152A","author":"Pan","year":"2010","journal-title":"Am J Med Genet Part A"},{"key":"10.1016\/j.jormas.2024.101809_bib0061","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1134\/S0026893315060102","article-title":"Significant association between nonsyndromic cleft lip with or without cleft palate and IRF6rs2235371 polymorphism in Iranian familiar population","volume":"49","author":"Jafary","year":"2015","journal-title":"Mol Biol"},{"key":"10.1016\/j.jormas.2024.101809_bib0062","first-page":"11732","article-title":"Association of polymorphisms of IRF6 to non-syndromic cleft lip with or without palate in a Guangdong population","volume":"9","author":"Wu","year":"2016","journal-title":"Int J Clin Exp Med"},{"key":"10.1016\/j.jormas.2024.101809_bib0063","doi-asserted-by":"crossref","first-page":"3207","DOI":"10.1002\/ajmg.a.35641","article-title":"Association of interactions among the IRF6 gene, the 8q24 region, and maternal folic acid intake with non-syndromic cleft lip\/palate in Mexican Mestizos","volume":"158A","author":"Vel\u00e1zquez-Arag\u00f3n","year":"2012","journal-title":"Am J Med Genet Part A"},{"key":"10.1016\/j.jormas.2024.101809_bib0064","doi-asserted-by":"crossref","first-page":"570","DOI":"10.21103\/Article11(4)_OA28","article-title":"Association of the irf6 rs2235371 and rs861019 polymorphisms with non-syndromic cleft lip with or without cleft palate in the yakut population","volume":"11","author":"Pavlova","year":"2021","journal-title":"Int J Biomed"},{"key":"10.1016\/j.jormas.2024.101809_bib0065","first-page":"175","article-title":"Association of MTHFR, BMP4, TGFA and IRF6 polymorphisms with non-syndromic cleft lip and palate in north indian patients","volume":"14","author":"Avasthi","year":"2022","journal-title":"Avicenna J Med Biotechnol"},{"key":"10.1016\/j.jormas.2024.101809_bib0066","doi-asserted-by":"crossref","first-page":"59","DOI":"10.17219\/dmp\/142760","article-title":"IRF6 rs2235371 as a risk factor for non-syndromic cleft palate only among the Deutero-Malay race in Indonesia and its effect on the IRF6 mRNA expression level","volume":"59","author":"Nasroen","year":"2022","journal-title":"Dent Med Probl"},{"key":"10.1016\/j.jormas.2024.101809_bib0067","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1086\/427344","article-title":"Strong evidence of linkage disequilibrium between polymorphisms at the IRF6 locus and nonsyndromic cleft lip with or without cleft palate, in an Italian population","volume":"76","author":"Scapoli","year":"2005","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.jormas.2024.101809_bib0068","article-title":"IRF6 rs2235375 single nucleotide polymorphism is associated with isolated non-syndromic cleft palate but not with cleft lip with or without palate in south Indian population","author":"Gurramkonda","year":"2017","journal-title":"Braz J Otorhinolaryngol"},{"key":"10.1016\/j.jormas.2024.101809_bib0069","doi-asserted-by":"crossref","first-page":"1857","DOI":"10.1007\/s43032-020-00203-9","article-title":"Association between IRF6 variants and nonsyndromic cleft lip with or without cleft palate in Chile","volume":"27","author":"Suazo","year":"2020","journal-title":"Reprod Sci"},{"key":"10.1016\/j.jormas.2024.101809_bib0070","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1016\/j.bbrc.2011.06.006","article-title":"Single-nucleotide polymorphisms (SNPs) of the IRF6 and TFAP2A in non-syndromic cleft lip with or without cleft palate (NSCLP) in a northern Chinese population","volume":"410","author":"Shi","year":"2011","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.jormas.2024.101809_bib0071","doi-asserted-by":"crossref","first-page":"2170","DOI":"10.1002\/ajmg.a.35526","article-title":"IRF6 is a risk factor for nonsyndromic cleft lip in the Brazilian population","volume":"158A","author":"Brito","year":"2012","journal-title":"Am J Med Genet Part A"},{"key":"10.1016\/j.jormas.2024.101809_bib0072","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1597\/12-234","article-title":"Association between interferon regulatory factor 6 gene polymorphisms and nonsyndromic cleft lip with or without cleft palate in a Chinese population","volume":"50","author":"Zhou","year":"2013","journal-title":"Cleft Palate-Craniofac J"},{"key":"10.1016\/j.jormas.2024.101809_bib0073","first-page":"25","article-title":"Lack of association between IRF6 polymorphisms and nonsyndromic oral clefts in South Indian population","volume":"1","author":"Gurramkonda","year":"2013","journal-title":"Dent"},{"key":"10.1016\/j.jormas.2024.101809_bib0074","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1002\/bdra.23221","article-title":"Nonsyndromic cleft lip with or without cleft palate in arab populations: genetic analysis of 15 risk loci in a novel case-control sample recruited in Yemen","volume":"100","author":"Aldhorae","year":"2014","journal-title":"Birth Defects Res Part A"},{"key":"10.1016\/j.jormas.2024.101809_bib0075","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1038\/s41415-023-5994-3","article-title":"Genetics and orofacial clefts: a clinical perspective","volume":"234","author":"Kini","year":"2023","journal-title":"Br Dent J"},{"key":"10.1016\/j.jormas.2024.101809_bib0076","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1597\/10-178","article-title":"Genetics of nonsyndromic orofacial clefts","volume":"49","author":"Rahimov","year":"2012","journal-title":"Cleft Palate Craniofac J"},{"key":"10.1016\/j.jormas.2024.101809_bib0077","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1177\/1055665620980238","article-title":"Screening of IRF6 variants in patients subjected to genetic association studies for nonsyndromic cleft lip\/palate","volume":"58","author":"Vel\u00e1zquez-Arag\u00f3n","year":"2021","journal-title":"Cleft Palate Craniofac J"},{"key":"10.1016\/j.jormas.2024.101809_bib0078","first-page":"73","article-title":"A meta-analysis for prevalence of lung cancer patients with SARS-CoV-2 infection during the COVID-19 pandemic","volume":"6","author":"Gholi-Nataj","year":"2022","journal-title":"Eurasian J Med Oncol"},{"key":"10.1016\/j.jormas.2024.101809_bib0079","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1016\/j.jhep.2019.01.010","article-title":"Radiation-primed hepatocyte transplantation in murine monogeneic dyslipidemia normalizes cholesterol and prevents atherosclerosis","volume":"70","author":"Barahman","year":"2019","journal-title":"J Hepatol"}],"container-title":["Journal of Stomatology, Oral and Maxillofacial Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S246878552400051X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S246878552400051X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,2]],"date-time":"2025-02-02T15:31:22Z","timestamp":1738510282000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S246878552400051X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":79,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["S246878552400051X"],"URL":"https:\/\/doi.org\/10.1016\/j.jormas.2024.101809","relation":{},"ISSN":["2468-7855"],"issn-type":[{"value":"2468-7855","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A comprehensive consolidation of data on the relationship between IRF6 polymorphisms and non-syndromic cleft lip\/palate susceptibility: From 79 case-control studies","name":"articletitle","label":"Article Title"},{"value":"Journal of Stomatology, Oral and Maxillofacial Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jormas.2024.101809","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"101809"}}