{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T08:02:28Z","timestamp":1784534548791,"version":"3.55.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Stomatology Oral and Maxillofacial Surgery"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.jormas.2025.102677","type":"journal-article","created":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T00:41:19Z","timestamp":1764981679000},"page":"102677","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Nasal irrigation reduces radiation-induced rhinosinusitis in nasopharyngeal carcinoma treated with volumetric modulated arc therapy"],"prefix":"10.1016","volume":"127","author":[{"given":"Jiarong","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanchen","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhining","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baihan","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-3150-4382","authenticated-orcid":false,"given":"Renxian","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jormas.2025.102677_bib0001","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/S0140-6736(19)30956-0","article-title":"Nasopharyngeal carcinoma","volume":"394","author":"Chen","year":"2019","journal-title":"Lancet"},{"key":"10.1016\/j.jormas.2025.102677_bib0002","doi-asserted-by":"crossref","DOI":"10.1016\/j.oraloncology.2020.104978","article-title":"Toxicity and dosimetric analysis of nasopharyngeal carcinoma patients undergoing radiotherapy with IMRT or VMAT: a regional center\u2019s experience","volume":"109","author":"He","year":"2020","journal-title":"Oral Oncol"},{"key":"10.1016\/j.jormas.2025.102677_bib0003","doi-asserted-by":"crossref","first-page":"930","DOI":"10.3389\/fonc.2020.00930","article-title":"Quality of life, toxicity and unmet needs in nasopharyngeal cancer survivors","volume":"10","author":"McDowell","year":"2020","journal-title":"Front Oncol"},{"key":"10.1016\/j.jormas.2025.102677_bib0004","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1177\/1945892418822448","article-title":"Radiation-induced rhinitis: cytological and olfactory changes","volume":"33","author":"G","year":"2019","journal-title":"Am J Rhinol Allergy"},{"key":"10.1016\/j.jormas.2025.102677_bib0005","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1002\/alr.22526","article-title":"Chronic rhinosinusitis after radiotherapy in patients with head and neck cancer: a population-based cohort study in Taiwan","volume":"10","author":"Lu","year":"2020","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jormas.2025.102677_bib0006","doi-asserted-by":"crossref","first-page":"2324","DOI":"10.3390\/cancers14092324","article-title":"Sinonasal side effects of chemotherapy and\/or radiation therapy for Head and Neck cancer: a literature review","volume":"14","author":"Riva","year":"2022","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.jormas.2025.102677_bib0007","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1002\/alr.23317","article-title":"The nasal and systemic inflammatory responses in early phase of acute radiation rhinosinusitis: a pilot study","volume":"14","author":"Zheng","year":"2024","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jormas.2025.102677_bib0008","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1370\/afm.552","article-title":"Qualitative aspects of nasal irrigation use by patients with chronic sinus disease in a multimethod study","volume":"4","author":"D","year":"2006","journal-title":"Ann Fam Med"},{"key":"10.1016\/j.jormas.2025.102677_bib0009","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1067\/mhn.2001.115909","article-title":"Nasal irrigation for the alleviation of sinonasal symptoms","volume":"125","author":"Dg","year":"2001","journal-title":"Otolaryngol.-Head Neck Surg"},{"key":"10.1016\/j.jormas.2025.102677_bib0010","doi-asserted-by":"crossref","first-page":"258","DOI":"10.2500\/ajr.2008.22.3166","article-title":"Nasal irrigation reduces postirradiation rhinosinusitis in patients with nasopharyngeal carcinoma","volume":"22","author":"Liang","year":"2008","journal-title":"Am J Rhinol"},{"key":"10.1016\/j.jormas.2025.102677_bib0011","doi-asserted-by":"crossref","first-page":"e41","DOI":"10.2500\/ajra.2015.29.4156","article-title":"Nasal cytological changes as late effects of radiotherapy for nasopharyngeal cancer","volume":"29","author":"G","year":"2015","journal-title":"Am J Rhinol Allergy"},{"key":"10.1016\/j.jormas.2025.102677_bib0012","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2023.e23554","article-title":"Clinical and dosimetric predictors of radiation-induced rhinosinusitis following VMAT for nasopharyngeal carcinoma: a retrospective study","volume":"10","author":"Bao","year":"2024","journal-title":"Heliyon"},{"key":"10.1016\/j.jormas.2025.102677_bib0013","doi-asserted-by":"crossref","first-page":"579","DOI":"10.5732\/cjc.012.10095","article-title":"Locoregional extension patterns of nasopharyngeal carcinoma and suggestions for clinical target volume delineation","volume":"31","author":"Li","year":"2012","journal-title":"Chin J Cancer"},{"key":"10.1016\/j.jormas.2025.102677_bib0014","doi-asserted-by":"crossref","DOI":"10.1016\/j.oraloncology.2020.104978","article-title":"Toxicity and dosimetric analysis of nasopharyngeal carcinoma patients undergoing radiotherapy with IMRT or VMAT: a regional center\u2019s experience","volume":"109","author":"He","year":"2020","journal-title":"Oral Oncol"},{"key":"10.1016\/j.jormas.2025.102677_bib0015","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.neurad.2021.01.010","article-title":"Imaging in chronic rhinosinusitis: a systematic review of MRI and CT diagnostic accuracy and reliability in severity staging","volume":"48","author":"Greguri\u0107","year":"2021","journal-title":"J Neuroradiol"},{"key":"10.1016\/j.jormas.2025.102677_bib0016","doi-asserted-by":"crossref","first-page":"82","DOI":"10.2500\/ajra.2013.27.3915","article-title":"Management of radiation-induced early nasal adhesion after radiotherapy for nasopharyngeal carcinoma","volume":"27","author":"Xiang","year":"2013","journal-title":"Am J Rhinol Allergy"},{"key":"10.1016\/j.jormas.2025.102677_bib0017","doi-asserted-by":"crossref","first-page":"3195","DOI":"10.1007\/s00405-014-3004-8","article-title":"Factors influencing the incidence of sinusitis in nasopharyngeal carcinoma patients after intensity-modulated radiation therapy","volume":"271","author":"Su","year":"2014","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"10.1016\/j.jormas.2025.102677_bib0018","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1067\/mhn.2001.115909","article-title":"Nasal irrigation for the alleviation of sinonasal symptoms","volume":"125","author":"Heatley","year":"2001","journal-title":"Otolaryngol\u2013Head Neck Surg"},{"key":"10.1016\/j.jormas.2025.102677_bib0019","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1177\/1945892418762872","article-title":"Does heating up saline for nasal irrigation improve mucociliary function in chronic rhinosinusitis?","volume":"32","author":"Nimsakul","year":"2018","journal-title":"Am J Rhinol Allergy"},{"key":"10.1016\/j.jormas.2025.102677_bib0020","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1002\/alr.22330","article-title":"Nasal saline irrigation: a clinical update","volume":"9","author":"Succar","year":"2019","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jormas.2025.102677_bib0021","doi-asserted-by":"crossref","first-page":"e41","DOI":"10.2500\/ajra.2015.29.4156","article-title":"Nasal cytological changes as late effects of radiotherapy for nasopharyngeal cancer","volume":"29","author":"Riva","year":"2015","journal-title":"Am J Rhinol Allergy"},{"key":"10.1016\/j.jormas.2025.102677_bib0022","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.radonc.2020.03.038","article-title":"Long-term defects of nasal epithelium barrier functions in patients with nasopharyngeal carcinoma post chemo-radiotherapy","volume":"148","author":"Zhou","year":"2020","journal-title":"Radiother Oncol"},{"key":"10.1016\/j.jormas.2025.102677_bib0023","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1667\/RR1535.1","article-title":"Absence of inflammatory response from upper airway epithelial cells after X irradiation","volume":"171","author":"Reiter","year":"2009","journal-title":"Radiat Res"},{"key":"10.1016\/j.jormas.2025.102677_bib0024","first-page":"1117","article-title":"Saline nasal irrigation for upper respiratory conditions","volume":"80","author":"Rabago","year":"2009","journal-title":"Am Fam Physician"},{"key":"10.1016\/j.jormas.2025.102677_bib0025","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1667\/RR1535.1","article-title":"Absence of inflammatory response from upper airway epithelial cells after X irradiation","volume":"171","author":"Reiter","year":"2009","journal-title":"Radiat Res"},{"issue":"5","key":"10.1016\/j.jormas.2025.102677_bib0026","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1378\/chest.106.5.1487","article-title":"Nasal hyperthermia and simple irrigation for perennial rhinitis. Changes in inflammatory mediators","volume":"106","author":"Georgitis","year":"1994","journal-title":"Chest"},{"key":"10.1016\/j.jormas.2025.102677_bib0027","first-page":"1117","article-title":"Saline nasal irrigation for upper respiratory conditions","volume":"80","author":"Rabago","year":"2009","journal-title":"Am Fam Physician"},{"key":"10.1016\/j.jormas.2025.102677_bib0028","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.1002\/alr.22330","article-title":"Nasal saline irrigation: a clinical update","volume":"9","author":"Succar","year":"2019","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jormas.2025.102677_bib0029","doi-asserted-by":"crossref","first-page":"34","DOI":"10.2500\/ajr.2008.22.3122","article-title":"Baby shampoo nasal irrigations for the symptomatic post-functional endoscopic sinus surgery patient","volume":"22","author":"Chiu","year":"2008","journal-title":"Am J Rhinol"},{"key":"10.1016\/j.jormas.2025.102677_bib0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.bjorl.2024.101436","article-title":"Non-antibiotic antimicrobial agents for chronic rhinosinusitis: a narrative review","volume":"90","author":"Caetano","year":"2024","journal-title":"Braz J Otorhinolaryngol"},{"key":"10.1016\/j.jormas.2025.102677_bib0031","article-title":"International consensus statement on allergy and rhinology: rhinosinusitis 2021","volume":"11","author":"Rr","year":"2021","journal-title":"Int Forum Allergy Rhinol"},{"key":"10.1016\/j.jormas.2025.102677_bib0032","doi-asserted-by":"crossref","first-page":"2324","DOI":"10.3390\/cancers14092324","article-title":"Sinonasal side effects of chemotherapy and\/or radiation therapy for Head and Neck cancer: a literature review","volume":"14","author":"Riva","year":"2022","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.jormas.2025.102677_bib0033","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1038\/nrc1950","article-title":"Preventing or reducing late side effects of radiation therapy: radiobiology meets molecular pathology","volume":"6","author":"Bentzen","year":"2006","journal-title":"Nat Rev Cancer"},{"key":"10.1016\/j.jormas.2025.102677_bib0034","doi-asserted-by":"crossref","DOI":"10.1177\/00368504251355373","article-title":"Bacterial lysates in allergic rhinitis and chronic rhinosinusitis: mechanisms and clinical evidence","volume":"108","author":"Huang","year":"2025","journal-title":"Sci Prog"},{"key":"10.1016\/j.jormas.2025.102677_bib0035","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1016\/j.jaip.2024.03.023","article-title":"Current management of allergic rhinitis","volume":"12","author":"Klimek","year":"2024","journal-title":"J Allergy Clin Immunol Pract"}],"container-title":["Journal of Stomatology Oral and Maxillofacial Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2468785525004628?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2468785525004628?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T07:10:22Z","timestamp":1784531422000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2468785525004628"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":35,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["S2468785525004628"],"URL":"https:\/\/doi.org\/10.1016\/j.jormas.2025.102677","relation":{},"ISSN":["2468-7855"],"issn-type":[{"value":"2468-7855","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Nasal irrigation reduces radiation-induced rhinosinusitis in nasopharyngeal carcinoma treated with volumetric modulated arc therapy","name":"articletitle","label":"Article Title"},{"value":"Journal of Stomatology Oral and Maxillofacial Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jormas.2025.102677","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Masson SAS. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"102677"}}