{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T13:25:07Z","timestamp":1780320307987,"version":"3.54.1"},"reference-count":34,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Orthopaedic Science"],"published-print":{"date-parts":[[2019,11]]},"DOI":"10.1016\/j.jos.2019.07.008","type":"journal-article","created":{"date-parts":[[2019,8,6]],"date-time":"2019-08-06T00:17:03Z","timestamp":1565050623000},"page":"1125-1129","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Olanexidine gluconate versus povidone-iodine for preventing surgical-site infection in orthopaedic surgery: A retrospective study"],"prefix":"10.1016","volume":"24","author":[{"given":"Mitsuru","family":"Asukai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsuyoshi","family":"Ohishi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomotada","family":"Fujita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsuya","family":"Nishida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaori","family":"Sugiura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukihiro","family":"Matsuyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.jos.2019.07.008_bib1","doi-asserted-by":"crossref","first-page":"2621","DOI":"10.1007\/s11999-010-1737-2","article-title":"Infirmity and injury complexity are risk factors for surgical-site infection after operative fracture care","volume":"469","author":"Bachoura","year":"2011","journal-title":"Clin Orthop Relat Res"},{"issue":"4","key":"10.1016\/j.jos.2019.07.008_bib2","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1086\/502033","article-title":"The impact of surgical-site infections following orthopedic surgery at a community hospital and a university hospital: adverse quality of life, excess length of stay, and extra cost","volume":"23","author":"Whitehouse","year":"2002","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1016\/j.jos.2019.07.008_bib3","first-page":"CD003949","article-title":"Preoperative skin antiseptics for preventing surgical wound infections after clean surgery","volume":"3","author":"Edwards","year":"2004","journal-title":"Cochrane Database Syst Rev"},{"issue":"4","key":"10.1016\/j.jos.2019.07.008_bib4","first-page":"365","article-title":"Staphylococci in orthopaedic surgical wounds","volume":"24","author":"Arciola","year":"2001","journal-title":"New Microbiol"},{"issue":"6","key":"10.1016\/j.jos.2019.07.008_bib5","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1086\/502431","article-title":"The value of bacterial culture during clean orthopedic surgery: a prospective study of 1,036 patients","volume":"25","author":"Bernard","year":"2004","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"5","key":"10.1016\/j.jos.2019.07.008_bib6","doi-asserted-by":"crossref","first-page":"980","DOI":"10.2106\/JBJS.D.01977","article-title":"Efficacy of surgical preparation solutions in foot and ankle surgery","volume":"87","author":"Ostrander","year":"2005","journal-title":"J\u00a0Bone Joint Surg Am"},{"issue":"8","key":"10.1016\/j.jos.2019.07.008_bib7","doi-asserted-by":"crossref","first-page":"1949","DOI":"10.2106\/JBJS.H.00768","article-title":"Efficacy of surgical preparation solutions in shoulder surgery","volume":"91","author":"Saltzman","year":"2009","journal-title":"J\u00a0Bone Joint Surg Am"},{"issue":"4","key":"10.1016\/j.jos.2019.07.008_bib8","first-page":"CD003949","article-title":"Preoperative skin antiseptics for preventing surgical wound infections after clean surgery","author":"Dumville","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"issue":"8","key":"10.1016\/j.jos.2019.07.008_bib9","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1007\/s00586-018-5513-4","article-title":"Epidemiological trends in spine surgery over 10 years in a multicenter database","volume":"27","author":"Kobayashi","year":"2018","journal-title":"Eur Spine J"},{"issue":"8","key":"10.1016\/j.jos.2019.07.008_bib10","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1016\/j.otsr.2018.08.009","article-title":"Ten-year epidemiological study in an orthopaedic and trauma surgery centre: are there risks involved in increasing scheduled arthroplasty volume without increasing resources?","volume":"104","author":"Erivan","year":"2018","journal-title":"Orthop Traumatol Surg Res"},{"issue":"2","key":"10.1016\/j.jos.2019.07.008_bib11","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.ocl.2015.09.004","article-title":"Impact of infection on fracture fixation","volume":"47","author":"Willey","year":"2016","journal-title":"Orthop Clin N Am"},{"key":"10.1016\/j.jos.2019.07.008_bib12","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1016\/S0960-894X(97)00297-7","article-title":"Synthesis and structure-activity relationship of novel antiseptics","volume":"7(13)","author":"Tsubouchi","year":"1997","journal-title":"Bioorg Med Chem Lett"},{"issue":"8","key":"10.1016\/j.jos.2019.07.008_bib13","doi-asserted-by":"crossref","first-page":"4551","DOI":"10.1128\/AAC.05048-14","article-title":"Bactericidal effects and mechanism of action of olanexidine gluconate, a new antiseptic","volume":"59","author":"Hagi","year":"2015","journal-title":"Antimicrob Agents Chemother"},{"issue":"Pt 1","key":"10.1016\/j.jos.2019.07.008_bib14","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1099\/jmm.0.080861-0","article-title":"Novel antiseptic compound OPB-2045G shows potent bactericidal activity against methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus both in\u00a0vitro and in\u00a0vivo: a pilot study in animals","volume":"64","author":"Inoue","year":"2015","journal-title":"J\u00a0Med Microbiol"},{"issue":"2","key":"10.1016\/j.jos.2019.07.008_bib15","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0196-6553(99)70088-X","article-title":"Guideline for prevention of surgical site infection, 1999. Centers for disease Control and prevention (CDC) hospital infection Control practices advisory committee","volume":"27","author":"Mangram","year":"1999","journal-title":"Am J Infect Contr"},{"issue":"1","key":"10.1016\/j.jos.2019.07.008_bib16","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1046\/j.1365-2672.1999.00482.x","article-title":"An evaluation of the suitability of the European suspension test to reflect in\u00a0vitro activity of antiseptics against clinically significant organisms","volume":"28","author":"Payne","year":"1999","journal-title":"Lett Appl Microbiol"},{"issue":"1","key":"10.1016\/j.jos.2019.07.008_bib17","first-page":"25","article-title":"Inhibition of povidone-iodine's bactericidal activity by common organic substances: an experimental study","volume":"98","author":"Zamora","year":"1985","journal-title":"Surgery"},{"issue":"4","key":"10.1016\/j.jos.2019.07.008_bib18","first-page":"414","article-title":"Chemical burn from povidone-iodine: case and review","volume":"10","author":"Rees","year":"2011","journal-title":"J\u00a0Drugs Dermatol"},{"issue":"3","key":"10.1016\/j.jos.2019.07.008_bib19","first-page":"152","article-title":"Aqueous based Povidone-iodine related chemical burn under the tourniquet (a case report) and literature review","volume":"10","author":"Supradeeptha","year":"2013","journal-title":"J\u00a0Orthop"},{"issue":"1","key":"10.1016\/j.jos.2019.07.008_bib20","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1159\/000431358","article-title":"Chlorhexidine anaphylaxis masquerading as septic shock","volume":"167","author":"Hong","year":"2015","journal-title":"Int Arch Allergy Immunol"},{"issue":"4","key":"10.1016\/j.jos.2019.07.008_bib21","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1111\/ans.13269","article-title":"Chlorhexidine-induced anaphylaxis in surgical patients: a review of the literature","volume":"86","author":"Sharp","year":"2016","journal-title":"ANZ J Surg"},{"issue":"1","key":"10.1016\/j.jos.2019.07.008_bib22","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1213\/01.ane.0000183641.09008.f2","article-title":"Fires in the operating room and intensive care unit: awareness is the key to prevention","volume":"102","author":"Prasad","year":"2006","journal-title":"Anesth Analg"},{"issue":"4","key":"10.1016\/j.jos.2019.07.008_bib23","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1097\/00000539-200110000-00031","article-title":"Fire in the operating room: a case report and laboratory study","volume":"93","author":"Barker","year":"2001","journal-title":"Anesth Analg"},{"issue":"12","key":"10.1016\/j.jos.2019.07.008_bib24","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1002\/bjs.1800631225","article-title":"Inflammable antiseptics and theatre fires","volume":"63","author":"Briscoe","year":"1976","journal-title":"Br J Surg"},{"issue":"2","key":"10.1016\/j.jos.2019.07.008_bib25","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1053\/jhin.1998.0559","article-title":"Efficacy of hand disinfectants against vancomycin-resistant enterococci in\u00a0vitro","volume":"42","author":"Kampf","year":"1999","journal-title":"J\u00a0Hosp Infect"},{"issue":"12","key":"10.1016\/j.jos.2019.07.008_bib26","first-page":"562","article-title":"Bactericidal effects of antiseptics and disinfectants against methicillin-resistant Staphylococcus aureus","volume":"10","author":"Kobayashi","year":"1989","journal-title":"Infect Control Hosp Epidemiol"},{"issue":"5","key":"10.1016\/j.jos.2019.07.008_bib27","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1099\/jmm.0.000462","article-title":"Effects of olanexidine gluconate on preoperative skin preparation: an experimental study in cynomolgus monkeys","volume":"66","author":"Nakata","year":"2017","journal-title":"J\u00a0Med Microbiol"},{"issue":"2","key":"10.1016\/j.jos.2019.07.008_bib28","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/s00590-014-1475-3","article-title":"Epidemiology and risk factors for surgical site infections in patients requiring orthopedic surgery","volume":"25","author":"Jain","year":"2015","journal-title":"Eur J Orthop Surg Traumatol"},{"issue":"3","key":"10.1016\/j.jos.2019.07.008_bib29","first-page":"439","article-title":"Surgical site infections in patients of orthopedic - trauma unit in district hospital in 2008-2012","volume":"67","author":"Walaszek","year":"2013","journal-title":"Przegl Epidemiol"},{"issue":"12","key":"10.1016\/j.jos.2019.07.008_bib30","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1016\/j.ajic.2013.03.305","article-title":"Epidemiology and outcomes of surgical site infections following orthopedic surgery","volume":"41","author":"Li","year":"2013","journal-title":"Am J Infect Contr"},{"issue":"2","key":"10.1016\/j.jos.2019.07.008_bib31","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1111\/cod.12877","article-title":"Allergic contact dermatitis caused by Olanedine\u00ae (olanexidine gluconate), a new antiseptic","volume":"78","author":"Nagai","year":"2018","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.jos.2019.07.008_bib32","series-title":"Global guidelines for the prevention of surgical site infection","author":"World Health Organization","year":"2016"},{"issue":"12","key":"10.1016\/j.jos.2019.07.008_bib33","doi-asserted-by":"crossref","first-page":"e276","DOI":"10.1016\/S1473-3099(16)30398-X","article-title":"WHO Guidelines Development Group. New WHO recommendations on preoperative measures for surgical site infection prevention: an evidence-based global perspective","volume":"16","author":"Allegranzi","year":"2016","journal-title":"Lancet Infect Dis"},{"issue":"8","key":"10.1016\/j.jos.2019.07.008_bib34","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1001\/jamasurg.2017.0904","article-title":"Healthcare infection Control practices advisory committee. Centers for disease Control and prevention guideline for the prevention of surgical site infection, 2017","volume":"152","author":"Berr\u00edos-Torres","year":"2017","journal-title":"JAMA Surg"}],"container-title":["Journal of Orthopaedic Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0949265819302106?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0949265819302106?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T19:30:59Z","timestamp":1760556659000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0949265819302106"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":34,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,11]]}},"alternative-id":["S0949265819302106"],"URL":"https:\/\/doi.org\/10.1016\/j.jos.2019.07.008","relation":{},"ISSN":["0949-2658"],"issn-type":[{"value":"0949-2658","type":"print"}],"subject":[],"published":{"date-parts":[[2019,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Olanexidine gluconate versus povidone-iodine for preventing surgical-site infection in orthopaedic surgery: A retrospective study","name":"articletitle","label":"Article Title"},{"value":"Journal of Orthopaedic Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jos.2019.07.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Published by Elsevier B.V. on behalf of The Japanese Orthopaedic Association.","name":"copyright","label":"Copyright"}]}}