{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T15:51:45Z","timestamp":1791129105630,"version":"4.1.0"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T00:00:00Z","timestamp":1786320000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["JP20he1302028"],"award-info":[{"award-number":["JP20he1302028"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Orthopaedic Translation"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.jot.2026.101201","type":"journal-article","created":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T09:00:34Z","timestamp":1787821234000},"page":"101201","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Preclinical evaluation of a fully threaded biodegradable magnesium alloy headless compression screw for enhanced fixation in small bones"],"prefix":"10.1016","volume":"60","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9426-7731","authenticated-orcid":false,"given":"Hiroshi","family":"Noguchi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6000-1556","authenticated-orcid":false,"given":"Kotaro","family":"Hanada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6675-5244","authenticated-orcid":false,"given":"Ryunosuke","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasukazu","family":"Totoki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yohei","family":"Tomaru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6034-1593","authenticated-orcid":false,"given":"Akira","family":"Ikumi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-3185-5076","authenticated-orcid":false,"given":"Akira","family":"Kitagawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3699-5938","authenticated-orcid":false,"given":"Sakiko","family":"Orui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lulu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajime","family":"Mishima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.jot.2026.101201_bib1","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.pmatsci.2008.06.004","article-title":"Ti based biomaterials, the ultimate choice for orthopaedic implants \u2013 a review","volume":"54","author":"Geetha","year":"2026","journal-title":"Prog Mater Sci"},{"issue":"1\u20132","key":"10.1016\/j.jot.2026.101201_bib2","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/0921-5093(96)10243-4","article-title":"The use of titanium for medical applications in the US","volume":"213","author":"Wang","year":"1996","journal-title":"Mater Sci Eng"},{"issue":"2","key":"10.1016\/j.jot.2026.101201_bib3","doi-asserted-by":"crossref","first-page":"113","DOI":"10.5435\/00124635-200602000-00006","article-title":"Hardware removal: indications and expectations","volume":"14","author":"Busam","year":"2006","journal-title":"J Am Acad Orthop Surg"},{"issue":"2","key":"10.1016\/j.jot.2026.101201_bib4","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1007\/s00776-005-0984-7","article-title":"Internal plate fixation of fractures: short history and recent developments","volume":"11","author":"Uhthoff","year":"2006","journal-title":"J Orthop Sci"},{"issue":"24","key":"10.1016\/j.jot.2026.101201_bib5","doi-asserted-by":"crossref","first-page":"2615","DOI":"10.1016\/S0142-9612(00)00129-0","article-title":"Clinical biocompatibility of biodegradable orthopaedic implants for internal fixation: a review","volume":"21","author":"B\u00f6stman","year":"2000","journal-title":"Biomaterials"},{"issue":"6","key":"10.1016\/j.jot.2026.101201_bib6","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1302\/0301-620X.74B6.1447246","article-title":"Absorbable pins of self-reinforced poly-L-lactic acid for fixation of fractures and osteotomies","volume":"74","author":"Pihlajam\u00e4ki","year":"1992","journal-title":"J Bone Joint Surg Br"},{"issue":"9","key":"10.1016\/j.jot.2026.101201_bib7","doi-asserted-by":"crossref","first-page":"1728","DOI":"10.1016\/j.biomaterials.2005.10.003","article-title":"Magnesium and its alloys as orthopedic biomaterials: a review","volume":"27","author":"Staiger","year":"2006","journal-title":"Biomaterials"},{"key":"10.1016\/j.jot.2026.101201_bib8","first-page":"468","article-title":"Research hotspots and trends of biodegradable magnesium and its alloys","volume":"4","author":"Zan","year":"2023","journal-title":"Smart Mater Med"},{"issue":"1","key":"10.1016\/j.jot.2026.101201_bib9","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1177\/08853282251324799","article-title":"Evaluation of the efficacy of magnesium alloy fixation screws in a goat femoral condylar fracture model","volume":"40","author":"Li","year":"2025","journal-title":"J Biomater Appl"},{"key":"10.1016\/j.jot.2026.101201_bib10","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.ijom.2019.03.966","article-title":"Influence of surface modifications on the degradation of standard-sized magnesium plates and healing of mandibular osteotomies in miniature pigs","volume":"49","author":"Naujokat","year":"2020","journal-title":"Int J Oral Maxillofac Surg"},{"issue":"15","key":"10.1016\/j.jot.2026.101201_bib11","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202000800","article-title":"Biodegradable magnesium alloys promote angio-osteogenesis to enhance bone repair","volume":"7","author":"Han","year":"2020","journal-title":"Adv Sci"},{"issue":"1","key":"10.1016\/j.jot.2026.101201_bib12","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1186\/s12880-017-0187-7","article-title":"Biodegradable magnesium Herbert screw \u2013 image quality and artifacts with radiography, CT and MRI","volume":"17","author":"Sonnow","year":"2017","journal-title":"BMC Med Imag"},{"issue":"5","key":"10.1016\/j.jot.2026.101201_bib13","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1177\/0885328212472215","article-title":"In vivo study of a biodegradable orthopedic screw (MgYREZr-alloy) in a rabbit model for up to 12 months","volume":"28","author":"Waizy","year":"2014","journal-title":"J Biomater Appl"},{"key":"10.1016\/j.jot.2026.101201_bib14","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1186\/1475-925X-12-62","article-title":"Biodegradable magnesium-based screw clinically equivalent to titanium screw in hallux valgus surgery: short term results of the first prospective, randomized, controlled clinical pilot study","volume":"12","author":"Windhagen","year":"2013","journal-title":"Biomed Eng Online"},{"issue":"6","key":"10.1016\/j.jot.2026.101201_bib15","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.bjoms.2017.04.007","article-title":"Fixation of fractures of the condylar head of the mandible with a new magnesium-alloy biodegradable cannulated headless bone screw","volume":"55","author":"Leonhardt","year":"2017","journal-title":"Br J Oral Maxillofac Surg"},{"issue":"12","key":"10.1016\/j.jot.2026.101201_bib16","article-title":"Fixation of small osteochondral fragments in a comminuted distal humerus fracture with magnesium bioabsorbable screws: a case report","volume":"10","author":"Aktan","year":"2018","journal-title":"Cureus"},{"issue":"S3","key":"10.1016\/j.jot.2026.101201_bib17","doi-asserted-by":"crossref","first-page":"S48","DOI":"10.1016\/j.injury.2018.09.055","article-title":"Intercondylar eminence fracture treated by resorbable magnesium screws osteosynthesis: a case series","volume":"49","author":"Gigante","year":"2018","journal-title":"Injury"},{"issue":"3","key":"10.1016\/j.jot.2026.101201_bib18","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.fas.2018.02.005","article-title":"Internal fixation of three-dimensional distal metatarsal I osteotomies in the treatment of hallux valgus deformities using biodegradable magnesium screws in comparison to titanium screws","volume":"25","author":"Klauser","year":"2019","journal-title":"Foot Ankle Surg"},{"issue":"2","key":"10.1016\/j.jot.2026.101201_bib19","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.jos.2017.11.005","article-title":"Bioabsorbable magnesium versus standard titanium compression screws for fixation of distal metatarsal osteotomies - 3 year results of a randomized clinical trial","volume":"23","author":"Plaass","year":"2018","journal-title":"J Orthop Sci"},{"issue":"6","key":"10.1016\/j.jot.2026.101201_bib20","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/j.fas.2018.09.001","article-title":"Magnesium-based bioabsorbable screw fixation for hallux valgus surgery \u2013 a suitable alternative to metallic implants","volume":"25","author":"Choo","year":"2019","journal-title":"Foot Ankle Surg"},{"issue":"8","key":"10.1016\/j.jot.2026.101201_bib21","doi-asserted-by":"crossref","first-page":"2265","DOI":"10.1016\/j.injury.2021.03.037","article-title":"Safety and performance of biodegradable magnesium-based implants in children and adolescents","volume":"52","author":"St\u00fcrznickel","year":"2021","journal-title":"Injury"},{"issue":"3","key":"10.1016\/j.jot.2026.101201_bib22","doi-asserted-by":"crossref","first-page":"721","DOI":"10.52312\/jdrs.2021.298","article-title":"Surgical outcomes of scaphoid fracture osteosynthesis with magnesium screws","volume":"32","author":"Polat","year":"2021","journal-title":"Joint Diseases and Related Surgery"},{"issue":"3","key":"10.1016\/j.jot.2026.101201_bib23","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1302\/1863-2548.15.210004","article-title":"Use of resorbable magnesium screws in children: systematic review of the literature and short-term follow-up from our series","volume":"15","author":"Baldini","year":"2021","journal-title":"J Child Orthop"},{"issue":"6","key":"10.1016\/j.jot.2026.101201_bib24","article-title":"Bioabsorbable magnesium screw fixation for tibial tubercle osteotomy; a preliminary study","volume":"92","author":"\u00dcnal","year":"2021","journal-title":"Acta Biomed"},{"issue":"N3","key":"10.1016\/j.jot.2026.101201_bib25","article-title":"Osteosynthesis devices in absorbable magnesium alloy in comparison to standard ones: a systematic review on effectiveness and safety","volume":"92","author":"Leigheb","year":"2021","journal-title":"Acta Biomed"},{"key":"10.1016\/j.jot.2026.101201_bib26","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1186\/s12891-019-2717-7","article-title":"Hallux valgus correction utilising a modified short scarf osteotomy with a magnesium biodegradable or titanium compression screws \u2013 a comparative study of clinical outcomes","volume":"20","author":"Atkinson","year":"2019","journal-title":"BMC Muscoskelet Disord"},{"key":"10.1016\/j.jot.2026.101201_bib27","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s10195-020-00547-7","article-title":"Bioabsorbable magnesium screw versus conventional titanium screw fixation for medial malleolar fractures","volume":"21","author":"May","year":"2020","journal-title":"J Orthop Traumatol"},{"key":"10.1016\/j.jot.2026.101201_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.foot.2021.101779","article-title":"Matched retrospective analysis of three different fixation devices for chevron osteotomy","volume":"47","author":"Wendelstein","year":"2021","journal-title":"Foot"},{"key":"10.1016\/j.jot.2026.101201_bib29","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/1749-799X-6-27","article-title":"A comparison of two headless compression screws for operative treatment of scaphoid fractures","volume":"6","author":"Grewal","year":"2011","journal-title":"J Orthop Surg Res"},{"issue":"7","key":"10.1016\/j.jot.2026.101201_bib30","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/j.injury.2012.03.015","article-title":"Biomechanical analysis of second-generation headless compression screws","volume":"43","author":"Assari","year":"2012","journal-title":"Injury"},{"issue":"11","key":"10.1016\/j.jot.2026.101201_bib31","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1007\/s10856-020-06445-y","article-title":"Pull-out forces of headless compression screws in variations of synthetic bone models imitating different types of scaphoid fractures in good bone quality","volume":"31","author":"Erhart","year":"2020","journal-title":"J Mater Sci Mater Med"},{"issue":"5","key":"10.1016\/j.jot.2026.101201_bib32","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1007\/s43465-020-00107-5","article-title":"Which headless compression screw produces the highest interfragmentary compression force in scaphoid fracture?","volume":"54","author":"Vishwanathan","year":"2020","journal-title":"Indian J Orthop"},{"key":"10.1016\/j.jot.2026.101201_bib33","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-019-51123-x","article-title":"Biodegradable surgical staple composed of magnesium alloy","volume":"9","author":"Amano","year":"2019","journal-title":"Sci Rep"},{"issue":"2","key":"10.1016\/j.jot.2026.101201_bib34","doi-asserted-by":"crossref","DOI":"10.1177\/10225536251360459","article-title":"The use of 3D-printed cutting guide improves the accuracy of distal chevron osteotomy for hallux valgus surgery","volume":"33","author":"Yee","year":"2025","journal-title":"J Orthop Surg"},{"issue":"1","key":"10.1016\/j.jot.2026.101201_bib35","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1186\/s13018-024-05327-1","article-title":"Fully-threaded cannulated screws versus partially-threaded cannulated screws for femoral neck fractures: a systematic review and meta-analysis","volume":"19","author":"Jia","year":"2024","journal-title":"J Orthop Surg Res"},{"issue":"1","key":"10.1016\/j.jot.2026.101201_bib36","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1186\/s12891-025-08559-2","article-title":"Magnesium versus titanium headless compression screws for fixation of a Hoffa-type fracture - a biomechanical in-vitro study","volume":"26","author":"Felten","year":"2025","journal-title":"BMC Muscoskelet Disord"},{"issue":"9","key":"10.1016\/j.jot.2026.101201_bib37","doi-asserted-by":"crossref","first-page":"1912","DOI":"10.1016\/j.jse.2020.02.009","article-title":"Biomechanical comparison of biodegradable magnesium screws and titanium screws for operative stabilization of displaced capitellar fractures","volume":"29","author":"Wagner","year":"2020","journal-title":"J Shoulder Elb Surg"},{"issue":"1","key":"10.1016\/j.jot.2026.101201_bib38","doi-asserted-by":"crossref","first-page":"282","DOI":"10.3390\/ijms25010282","article-title":"Magnesium alloys in orthopedics: a systematic review on approaches, coatings and strategies to improve biocompatibility, osteogenic properties and osteointegration capabilities","volume":"25","author":"Giavaresi","year":"2024","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jot.2026.101201_bib39","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.biomaterials.2017.12.007","article-title":"Magnesium alloy based interference screw developed for ACL reconstruction attenuates peri-tunnel bone loss in rabbits","volume":"157","author":"Wang","year":"2018","journal-title":"Biomaterials"},{"issue":"10","key":"10.1016\/j.jot.2026.101201_bib40","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.2106\/00004623-199810000-00006","article-title":"Metal release in patients who have had a primary total hip arthroplasty. A prospective, controlled, longitudinal study","volume":"80","author":"Jacobs","year":"1998","journal-title":"J Bone Joint Surg"},{"key":"10.1016\/j.jot.2026.101201_bib41","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.actbio.2015.07.025","article-title":"In vivo evaluation of a magnesium-based degradable intramedullary nailing system in a sheep model","volume":"25","author":"R\u00f6ssig","year":"2015","journal-title":"Acta Biomater"},{"key":"10.1016\/j.jot.2026.101201_bib42","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/j.actbio.2016.08.002","article-title":"Biocompatibility and degradation of LAE442-based magnesium alloys after implantation of up to 3.5 years in a rabbit model","volume":"44","author":"Angrisani","year":"2016","journal-title":"Acta Biomater"}],"container-title":["Journal of Orthopaedic Translation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214031X26001609?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2214031X26001609?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T14:51:35Z","timestamp":1791125495000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2214031X26001609"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":42,"alternative-id":["S2214031X26001609"],"URL":"https:\/\/doi.org\/10.1016\/j.jot.2026.101201","relation":{},"ISSN":["2214-031X"],"issn-type":[{"value":"2214-031X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Preclinical evaluation of a fully threaded biodegradable magnesium alloy headless compression screw for enhanced fixation in small bones","name":"articletitle","label":"Article Title"},{"value":"Journal of Orthopaedic Translation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jot.2026.101201","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier B.V. on behalf of Chinese Speaking Orthopaedic Society.","name":"copyright","label":"Copyright"}],"article-number":"101201"}}