{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:23:54Z","timestamp":1761956634946,"version":"build-2065373602"},"reference-count":16,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2009,4,1]],"date-time":"2009-04-01T00:00:00Z","timestamp":1238544000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,4,1]],"date-time":"2009-04-01T00:00:00Z","timestamp":1238544000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jpagonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pediatric and Adolescent Gynecology"],"published-print":{"date-parts":[[2009,4]]},"DOI":"10.1016\/j.jpag.2008.07.015","type":"journal-article","created":{"date-parts":[[2009,4,6]],"date-time":"2009-04-06T04:34:10Z","timestamp":1238992450000},"page":"137-140","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Managing Polycystic Ovary Syndrome in Adolescent Patients"],"prefix":"10.1016","volume":"22","author":[{"given":"Elise DeVore","family":"Berlan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. Jean","family":"Emans","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpag.2008.07.015_bib1","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1001\/archpedi.156.6.556","article-title":"Quality of life in adolescent girls with polycystic ovary syndrome","volume":"156","author":"Trent","year":"2002","journal-title":"Arch Pediatr Adolesc Med"},{"key":"10.1016\/j.jpag.2008.07.015_bib2","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1067\/mpd.2001.109603","article-title":"Early metabolic abnormalities in adolescent girls with polycystic ovarian syndrome","volume":"138","author":"Lewy","year":"2001","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpag.2008.07.015_bib3","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1210\/jcem.87.3.8305","article-title":"Screening for abnormal glucose tolerance in adolescents with polycystic ovary syndrome","volume":"87","author":"Palmert","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpag.2008.07.015_bib4","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1210\/jc.2005-1666","article-title":"Adolescent girls with polycystic ovary syndrome have an increased risk of the metabolic syndrome associated with increasing androgen levels independent of obesity and insulin resistance","volume":"91","author":"Coviello","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpag.2008.07.015_bib5","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.beem.2006.03.008","article-title":"Role of lifestyle modification in the management of polycystic ovary syndrome","volume":"20","author":"Hoeger","year":"2006","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"10.1016\/j.jpag.2008.07.015_bib6","first-page":"3469","article-title":"Body fat distribution and steroid hormone concentrations in obese adolescent girls before and after weight reduction","volume":"80","author":"Wabitsch","year":"1995","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpag.2008.07.015_bib7","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1056\/NEJM200105033441801","article-title":"Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance","volume":"344","author":"Tuomilehto","year":"2001","journal-title":"N Engl J Med"},{"issue":"Suppl 4","key":"10.1016\/j.jpag.2008.07.015_bib8","doi-asserted-by":"crossref","first-page":"S254","DOI":"10.1542\/peds.2007-2329F","article-title":"Recommendations for treatment of child and adolescent overweight and obesity","volume":"120","author":"Spear","year":"2007","journal-title":"Pediatrics"},{"issue":"3 Suppl","key":"10.1016\/j.jpag.2008.07.015_bib9","doi-asserted-by":"crossref","first-page":"23S","DOI":"10.1016\/S0010-7824(98)00079-1","article-title":"Uniqueness of oral contraceptive progestins","volume":"58","author":"Carr","year":"1998","journal-title":"Contraception"},{"key":"10.1016\/j.jpag.2008.07.015_bib10","unstructured":"FDA Approves Update to Label on Birth Control Patch. Available: http:\/\/www.fda.gov\/bbs\/topics\/NEWS\/2008\/NEW01781.html. Updated 2008. Accessed March 7, 2008."},{"key":"10.1016\/j.jpag.2008.07.015_bib11","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1093\/humrep\/dem005","article-title":"Metformin versus oral contraceptive pill in polycystic ovary syndrome: A Cochrane review","volume":"22","author":"Costello","year":"2007","journal-title":"Hum Reprod"},{"key":"10.1016\/j.jpag.2008.07.015_bib12","doi-asserted-by":"crossref","first-page":"3595","DOI":"10.1210\/jcem.86.8.7756","article-title":"Sensitization to insulin induces ovulation in non-obese adolescents with anovulatory hyperandrogenism","volume":"86","author":"Ibanez","year":"2001","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpag.2008.07.015_bib13","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1210\/jcem.87.4.8398","article-title":"Metformin therapy in obese adolescents with polycystic ovary syndrome and impaired glucose tolerance: Amelioration of exaggerated adrenal response to adrenocorticotropin with reduction of insulinemia\/insulin resistance","volume":"87","author":"Arslanian","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpag.2008.07.015_bib14","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1515\/JPEM.2005.18.8.761","article-title":"Randomized controlled trial evaluating response to metformin versus standard therapy in the treatment of adolescents with polycystic ovary syndrome","volume":"18","author":"Allen","year":"2005","journal-title":"J Pediatr Endocrinol Metab"},{"key":"10.1016\/j.jpag.2008.07.015_bib15","doi-asserted-by":"crossref","first-page":"2252","DOI":"10.1093\/humrep\/del185","article-title":"Metformin treatment is effective in obese teenage girls with PCOS","volume":"21","author":"De Leo","year":"2006","journal-title":"Hum Reprod"},{"key":"10.1016\/j.jpag.2008.07.015_bib16","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1001\/archpedi.160.3.241","article-title":"Randomized placebo-controlled trial of metformin for adolescents with polycystic ovary syndrome","volume":"160","author":"Bridger","year":"2006","journal-title":"Arch Pediatr Adolesc Med"}],"container-title":["Journal of Pediatric and Adolescent Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1083318808002441?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1083318808002441?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T13:37:03Z","timestamp":1761053823000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1083318808002441"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,4]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009,4]]}},"alternative-id":["S1083318808002441"],"URL":"https:\/\/doi.org\/10.1016\/j.jpag.2008.07.015","relation":{},"ISSN":["1083-3188"],"issn-type":[{"type":"print","value":"1083-3188"}],"subject":[],"published":{"date-parts":[[2009,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Managing Polycystic Ovary Syndrome in Adolescent Patients","name":"articletitle","label":"Article Title"},{"value":"Journal of Pediatric and Adolescent Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpag.2008.07.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}