{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:38:29Z","timestamp":1761957509720,"version":"build-2065373602"},"reference-count":25,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T00:00:00Z","timestamp":1254355200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T00:00:00Z","timestamp":1254355200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jpagonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pediatric and Adolescent Gynecology"],"published-print":{"date-parts":[[2009,10]]},"DOI":"10.1016\/j.jpag.2008.07.020","type":"journal-article","created":{"date-parts":[[2009,7,12]],"date-time":"2009-07-12T04:28:51Z","timestamp":1247372931000},"page":"330-335","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Diagnostic Quandary: Premature Ovarian Failure and Galactosemia Variants in Adolescent Girls with Delayed Puberty"],"prefix":"10.1016","volume":"22","author":[{"given":"Amanda C.","family":"Flint","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy J.","family":"Hopwood","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josephine Z.","family":"Kasa-Vubu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpag.2008.07.020_bib1","series-title":"UpToDate","article-title":"Clinical features and diagnosis of galactosemia","author":"Sutton","year":"2007"},{"key":"10.1016\/j.jpag.2008.07.020_bib2","series-title":"Cecil Textbook of Medicine","first-page":"1268","article-title":"Galactosemia","author":"Elsas","year":"2004"},{"key":"10.1016\/j.jpag.2008.07.020_bib3","series-title":"UpToDate","article-title":"Management and outcome of galactosemia","author":"Sutton","year":"2007"},{"key":"10.1016\/j.jpag.2008.07.020_bib4","unstructured":"Chen Y-T: Defects in galactose metabolism. In: Nelson Textbook of Pediatrics, (17th ed.). Edited by RE Behrman, RM Kliegman, HB Jenson. Philadelphia, W.B. Saunders Company, pp 475\u2013476"},{"key":"10.1016\/j.jpag.2008.07.020_bib5","series-title":"UpToDate","article-title":"Pathogenesis and causes of spontaneous premature ovarian failure","author":"Welt","year":"2007"},{"key":"10.1016\/j.jpag.2008.07.020_bib6","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1007\/BF01800204","article-title":"Long-term prognosis in galactosaemia: results of a survey of 350 cases","volume":"13","author":"Waggoner","year":"1990","journal-title":"J\u00a0Inherit Metab Dis"},{"key":"10.1016\/j.jpag.2008.07.020_bib7","series-title":"Williams Textbook of Endocrinology","first-page":"1195","article-title":"Miscellaneous causes of ovarian failure","author":"Grumbach","year":"2003"},{"key":"10.1016\/j.jpag.2008.07.020_bib8","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1007\/BF01799450","article-title":"Gonadal function in patients with galactosaemia","volume":"9","author":"Kaufman","year":"1986","journal-title":"J Inherit Metab Dis"},{"key":"10.1016\/j.jpag.2008.07.020_bib9","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1093\/humupd\/dml031","article-title":"Pathophysiology of impaired ovarian function in galactosaemia","volume":"12","author":"Forges","year":"2006","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.jpag.2008.07.020_bib10","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1126\/science.7302587","article-title":"Reduction in oocyte number following prenatal exposure to a diet high in galactose","volume":"214","author":"Chen","year":"1981","journal-title":"Science"},{"key":"10.1016\/j.jpag.2008.07.020_bib11","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.reprotox.2005.07.001","article-title":"Dietary galactose inhibits GDF-9 mediated follicular development in the rat ovary","volume":"21","author":"Liu","year":"2006","journal-title":"Reprod Toxicol"},{"key":"10.1016\/j.jpag.2008.07.020_bib12","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1093\/humrep\/deg058","article-title":"Prenatal exposure to high galactose adversely affects initial gonadal pool of germ cells in rats","volume":"18","author":"Bandyopadhyay","year":"2003","journal-title":"Hum Reprod"},{"key":"10.1016\/j.jpag.2008.07.020_bib13","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1007\/s004310050568","article-title":"Altered follicle stimulating hormone isoforms in female galactosaemia patients","volume":"156","author":"Prestoz","year":"1997","journal-title":"Eur J Pediatr"},{"key":"10.1016\/j.jpag.2008.07.020_bib14","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1067\/mpd.2000.109148","article-title":"Risk factors for premature ovarian failure in females with galactosemia","volume":"137","author":"Guerrero","year":"2000","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpag.2008.07.020_bib15","unstructured":"Rapaport R: Hypergonadotropic hypogonadism in the female. In: Nelson Textbook of Pediatrics, (17th ed.). Edited by RE Behrman, RM Kliegman, HB Jenson HB. Philadelphia, W.B. Saunders Company, pp 1931\u20131935"},{"key":"10.1016\/j.jpag.2008.07.020_bib16","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/S0140-6736(87)92948-5","article-title":"Failure to identify heterozygotes for galactosaemia in women with premature ovarian failure","volume":"2","author":"Fraser","year":"1987","journal-title":"Lancet"},{"key":"10.1016\/j.jpag.2008.07.020_bib17","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.fertnstert.2004.09.041","article-title":"Galactose-1-phosphate uridyl transferase gene mutations in women with premature ovarian failure","volume":"84","author":"Mlinar","year":"2005","journal-title":"Fertil Steril"},{"key":"10.1016\/j.jpag.2008.07.020_bib18","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/S0015-0282(16)56232-3","article-title":"Results of a survey of carrier women for the galactosemia gene","volume":"60","author":"Kaufman","year":"1993","journal-title":"Fertil Steril"},{"key":"10.1016\/j.jpag.2008.07.020_bib19","unstructured":"Cramer DW, et al: Society for Gynecologic Investigation, 1989; Annual Meeting Abstract Number 400."},{"key":"10.1016\/j.jpag.2008.07.020_bib20","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1086\/498985","article-title":"Epimerase-deficiency galactosemia is not a binary condition","volume":"78","author":"Openo","year":"2006","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.jpag.2008.07.020_bib21","series-title":"UpToDate","article-title":"Disorders of tyrosine metabolism","author":"Grompe","year":"2007"},{"key":"10.1016\/j.jpag.2008.07.020_bib22","doi-asserted-by":"crossref","first-page":"2191","DOI":"10.1210\/jcem.81.3.8772552","article-title":"Self-concept and behavior in adolescent girls with Turner syndrome: potential estrogen effects","volume":"81","author":"Ross","year":"1996","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpag.2008.07.020_bib23","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/S0029-7844(97)00583-8","article-title":"Bone loss in young women with karyotypically normal spontaneous premature ovarian failure","volume":"91","author":"Anasti","year":"1998","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.jpag.2008.07.020_bib24","unstructured":"Berry GT, Anadiotis GA: Galactose-1-Phosphate Uridyltransferase Deficiency (Galactosemia). eMedicine Sep 22, 2006, www.emedicine.com\/ped\/topic818.htm"},{"year":"2001","series-title":"National Newborn Screening Report \u2013 1997","key":"10.1016\/j.jpag.2008.07.020_bib25"}],"container-title":["Journal of Pediatric and Adolescent Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1083318808002490?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1083318808002490?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T13:37:12Z","timestamp":1761053832000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1083318808002490"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10]]},"references-count":25,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2009,10]]}},"alternative-id":["S1083318808002490"],"URL":"https:\/\/doi.org\/10.1016\/j.jpag.2008.07.020","relation":{},"ISSN":["1083-3188"],"issn-type":[{"type":"print","value":"1083-3188"}],"subject":[],"published":{"date-parts":[[2009,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Diagnostic Quandary: Premature Ovarian Failure and Galactosemia Variants in Adolescent Girls with Delayed Puberty","name":"articletitle","label":"Article Title"},{"value":"Journal of Pediatric and Adolescent Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpag.2008.07.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}