{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T01:13:37Z","timestamp":1761959617943,"version":"build-2065373602"},"reference-count":36,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2010,8,1]],"date-time":"2010-08-01T00:00:00Z","timestamp":1280620800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,8,1]],"date-time":"2010-08-01T00:00:00Z","timestamp":1280620800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Pfizer\/Pharmacia"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jpagonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pediatric and Adolescent Gynecology"],"published-print":{"date-parts":[[2010,8]]},"DOI":"10.1016\/j.jpag.2009.11.004","type":"journal-article","created":{"date-parts":[[2010,5,17]],"date-time":"2010-05-17T02:22:33Z","timestamp":1274062953000},"page":"209-214","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Inadequate Vitamin D Status in Adolescents with Substantial Bone Mineral Density Loss During the Use of Depot Medroxyprogesterone Acetate Injectable Contraceptive: A Pilot Study"],"prefix":"10.1016","volume":"23","author":[{"given":"Z.","family":"Harel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Wolter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.A.","family":"Gold","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Cromer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Bruner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Stager","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Bachrach","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Hertweck","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Coupey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.C.","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Burkman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Bone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpag.2009.11.004_bib1","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/S0031-3955(05)70148-6","article-title":"The use of long-acting contraceptives in adolescents","volume":"46","author":"Harel","year":"1999","journal-title":"Pediatr Clin North Am"},{"key":"10.1016\/j.jpag.2009.11.004_bib2","series-title":"Contraceptive Technology","article-title":"Contraceptive efficacy","author":"Trussell","year":"2007"},{"key":"10.1016\/j.jpag.2009.11.004_bib3","doi-asserted-by":"crossref","first-page":"4","DOI":"10.2307\/2991517","article-title":"Trends in contraceptive use in the United States: 1982-1995","volume":"30","author":"Piccinino","year":"1998","journal-title":"Fam Plann Perspect"},{"year":"2000","series-title":"US Bureau of the Census: United States Census 2000 Summary File 1","key":"10.1016\/j.jpag.2009.11.004_bib4"},{"key":"10.1016\/j.jpag.2009.11.004_bib5","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1136\/bmj.303.6793.13","article-title":"Bone density in women receiving depot medroxyprogesterone acetate for contraception","volume":"303","author":"Cundy","year":"1991","journal-title":"BMJ"},{"key":"10.1016\/j.jpag.2009.11.004_bib6","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1111\/j.1471-0528.1998.tb10211.x","article-title":"Bone density in long-term users of depot medroxyprogesterone acetate","volume":"105","author":"Gbolade","year":"1998","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1016\/j.jpag.2009.11.004_bib7","first-page":"569","article-title":"Spinal bone density in women using depot medroxyprogesterone contraception","volume":"92","author":"Cundy","year":"1998","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.jpag.2009.11.004_bib8","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/S0010-7824(98)00125-5","article-title":"Bone density amongst long-term users of medroxyprogesterone acetate as a contraceptive","volume":"58","author":"Paiva","year":"1998","journal-title":"Contraception"},{"key":"10.1016\/j.jpag.2009.11.004_bib9","first-page":"233","article-title":"Bone mineral density in women using depot medroxyprogesterone for contraception","volume":"93","author":"Scholes","year":"1999","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.jpag.2009.11.004_bib10","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0010-7824(98)00144-9","article-title":"Long-term depot medroxyprogesterone acetate and bone mineral density","volume":"59","author":"Tang","year":"1999","journal-title":"Contraception"},{"key":"10.1016\/j.jpag.2009.11.004_bib11","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1016\/S0022-3476(96)70148-8","article-title":"A prospective comparison of bone density in adolescent girls receiving depot medroxyprogesterone acetate (Depo-Provera), levonorgestrel (Norplant), or oral contraceptives","volume":"129","author":"Cromer","year":"1996","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpag.2009.11.004_bib12","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/S1054-139X(02)00567-0","article-title":"Bone mineral density in a cohort of adolescent women using depot medroxprogesterone acetate for one to two years","volume":"32","author":"Busen","year":"2003","journal-title":"J Adolesc Health"},{"key":"10.1016\/j.jpag.2009.11.004_bib13","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.jpag.2003.11.017","article-title":"Bone mineral density in adolescent females using depot medroxyprogesterone acetate","volume":"17","author":"Lara-Torre","year":"2004","journal-title":"J Pediatr Adolesc Gynecol"},{"key":"10.1016\/j.jpag.2009.11.004_bib14","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.jadohealth.2004.07.005","article-title":"Depot medroxyprogesterone acetate, oral contraceptives and bone mineral density in a cohort of adolescent girls","volume":"35","author":"Cromer","year":"2004","journal-title":"J Adolesc Health"},{"key":"10.1016\/j.jpag.2009.11.004_bib15","unstructured":"http:\/\/www.fda.gov\/medwatch\/SAFETY\/2004\/DepoProvera_Label.pdf. Accessed January 27, 2005"},{"key":"10.1016\/j.jpag.2009.11.004_bib16","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.jadohealth.2006.03.011","article-title":"Depot medroxyprogesterone acetate and bone mineral density in adolescents-the black box warning: A position paper of the Society for Adolescent Medicine","volume":"39","author":"Cromer","year":"2006","journal-title":"J Adol Health"},{"key":"10.1016\/j.jpag.2009.11.004_bib17","first-page":"179","article-title":"Effects of contraceptive use on bone biochemical markers in young women","volume":"86","author":"Ott","year":"2001","journal-title":"J Clin Endocrinol Metabol"},{"key":"10.1016\/j.jpag.2009.11.004_bib18","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.jpag.2004.09.013","article-title":"Bone biochemical markers in adolescent girls using either depot medroxyprogesterone acetate or an oral contraceptive","volume":"17","author":"Rome","year":"2004","journal-title":"J Pediatr Adolesc Gynecol"},{"key":"10.1016\/j.jpag.2009.11.004_bib19","first-page":"339","article-title":"Serum medroxyprogesterone (MPA), sex hormone binding globulin, gonadal steroids, gonadotrophins and prolactin in women during long-term use of depo-MPA as a contraceptive","volume":"99","author":"Jeppsson","year":"1982","journal-title":"Acta Endocrinol"},{"key":"10.1016\/j.jpag.2009.11.004_bib20","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/S0015-0282(01)01748-4","article-title":"Magnitude and variability of sequential estradiol and progesterone concentrations in women using depot medroxyprogesterone acetate for contraception","volume":"75","author":"Clark","year":"2001","journal-title":"Fertil Steril"},{"key":"10.1016\/j.jpag.2009.11.004_bib21","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.contraception.2007.11.002","article-title":"Longitudinal study of depot medroxyprogesterone acetate (Depo-Provera) effects on bone health in adolescents: Study design, population characteristics and baseline bone mineral density","volume":"77","author":"Johnson","year":"2008","journal-title":"Contraception"},{"key":"10.1016\/j.jpag.2009.11.004_bib22","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1056\/NEJMra070553","article-title":"Vitamin D deficiency","volume":"357","author":"Holick","year":"2007","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jpag.2009.11.004_bib23","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1001\/archpedi.158.6.531","article-title":"Prevalence of vitamin D deficiency among healthy adolescents","volume":"158","author":"Gordon","year":"2004","journal-title":"Arch Pediatr Adolesc Med"},{"key":"10.1016\/j.jpag.2009.11.004_bib24","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.jadohealth.2004.07.015","article-title":"Vitamin D deficiency in adolescent females","volume":"37","author":"Harkness","year":"2005","journal-title":"J Adolesc Health"},{"key":"10.1016\/j.jpag.2009.11.004_bib25","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1093\/ajcn\/76.6.1446","article-title":"Vitamin D and attainment of peak bone mass among peripubertal Finnish girls: A 3-year prospective study","volume":"76","author":"Lehtonen-Veromaa","year":"2002","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.jpag.2009.11.004_bib26","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1359\/jbmr.060302","article-title":"A positive dose-response effect of vitamin D supplementation on site-specific bone mineral augmentation in adolescent girls: A double-blinded randomized placebo-controlled 1-year intervention","volume":"21","author":"Viljakainen","year":"2006","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.jpag.2009.11.004_bib27","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/j.amjmed.2003.12.029","article-title":"Positive association between 25 (OH) D levels and bone mineral density: A population-based study of younger and older adults","volume":"116","author":"Bischoff-Ferrari","year":"2004","journal-title":"Am J Med"},{"key":"10.1016\/j.jpag.2009.11.004_bib28","doi-asserted-by":"crossref","first-page":"1735S","DOI":"10.1093\/ajcn\/80.6.1735S","article-title":"Vitamin D requirements: current and future","volume":"80","author":"Weaver","year":"2004","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.jpag.2009.11.004_bib29","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1093\/ajcn\/74.2.206","article-title":"Vitamin D status affects serum parathyroid hormone concentrations during winter in female adolescents: Associations with forearm bone mineral density","volume":"74","author":"Outila","year":"2001","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.jpag.2009.11.004_bib30","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1542\/peds.2008-1862","article-title":"Section on Breastfeeding and Committee on Nutrition: Prevention of rickets and vitamin D deficiency in infants, children, and adolescents","volume":"122","author":"Wagner","year":"2008","journal-title":"Pediatrics"},{"year":"1997","series-title":"Standing Committee on the Scientific Evaluation of Dietary Reference Intakes, Food and Nutrition Board, Institute of Medicine: Dietary reference intakes for calcium, phosphorus, magnesium, vitamin D, and fluoride","key":"10.1016\/j.jpag.2009.11.004_bib31"},{"key":"10.1016\/j.jpag.2009.11.004_bib32","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1016\/S0899-9007(97)83011-0","article-title":"Calcium and osteoporosis","volume":"13","author":"Nordin","year":"1997","journal-title":"Nutrition"},{"key":"10.1016\/j.jpag.2009.11.004_bib33","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1111\/j.1469-7793.1998.313bi.x","article-title":"Oestrogen deficiency impairs intestinal calcium absorption in the rat","volume":"511","author":"O'Loughlin","year":"1998","journal-title":"J Physiol"},{"key":"10.1016\/j.jpag.2009.11.004_bib34","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1210\/endo.140.1.6408","article-title":"Estrogen increases 1,25-dihydroxyvitamin D receptors expression and bioresponse in the rat duodenal mucosa","volume":"140","author":"Liel","year":"1999","journal-title":"Endocrinology"},{"key":"10.1016\/j.jpag.2009.11.004_bib35","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/S0006-291X(02)02657-8","article-title":"Estrogens (E2) regulate expression and response of 1,25-dihydroxyvitamin D3 receptors in bone cells: Changes with aging and hormone deprivation","volume":"299","author":"Duque","year":"2002","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.jpag.2009.11.004_bib36","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/S0010-7824(02)00460-2","article-title":"A 2-year prospective study on the effects of depot medroxyprogesterone acetate on bone mass-response to estrogen and calcium therapy in individual users","volume":"67","author":"Merki-Feld","year":"2003","journal-title":"Contraception"}],"container-title":["Journal of Pediatric and Adolescent Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1083318809003556?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1083318809003556?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T13:37:51Z","timestamp":1761053871000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1083318809003556"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8]]},"references-count":36,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2010,8]]}},"alternative-id":["S1083318809003556"],"URL":"https:\/\/doi.org\/10.1016\/j.jpag.2009.11.004","relation":{},"ISSN":["1083-3188"],"issn-type":[{"type":"print","value":"1083-3188"}],"subject":[],"published":{"date-parts":[[2010,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Inadequate Vitamin D Status in Adolescents with Substantial Bone Mineral Density Loss During the Use of Depot Medroxyprogesterone Acetate Injectable Contraceptive: A Pilot Study","name":"articletitle","label":"Article Title"},{"value":"Journal of Pediatric and Adolescent Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpag.2009.11.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}