{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T16:09:10Z","timestamp":1783613350663,"version":"3.55.0"},"reference-count":32,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jpagonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pediatric and Adolescent Gynecology"],"published-print":{"date-parts":[[2013,10]]},"DOI":"10.1016\/j.jpag.2013.06.003","type":"journal-article","created":{"date-parts":[[2013,9,5]],"date-time":"2013-09-05T01:48:25Z","timestamp":1378345705000},"page":"285-289","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":47,"title":["Prevalence of Hemostatic Disorders in Adolescents with Abnormal Uterine Bleeding"],"prefix":"10.1016","volume":"26","author":[{"given":"V.","family":"Seravalli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Linari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Peruzzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Dei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Paladino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Bruni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpag.2013.06.003_bib1","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1111\/j.1471-0528.2004.00176.x","article-title":"von Willebrand disease in women with menorrhagia: a systematic review","volume":"111","author":"Shankar","year":"2004","journal-title":"BJOG"},{"issue":"6 Suppl","key":"10.1016\/j.jpag.2013.06.003_bib2","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/j.jpag.2010.08.005","article-title":"von Willebrand disease in the pediatric and adolescent population","volume":"23","author":"Mikhail","year":"2010","journal-title":"J Pediatr Adolesc Gynecol"},{"key":"10.1016\/j.jpag.2013.06.003_bib3","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1182\/blood.V69.2.454.454","article-title":"Epidemiological investigation of the prevalence of von Willebrand's disease","volume":"69","author":"Rodeghiero","year":"1987","journal-title":"Blood"},{"key":"10.1016\/j.jpag.2013.06.003_bib4","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1111\/hae.12012","article-title":"Menstrual bleeding patterns and prevalence of bleeding disorders in a multidisciplinary adolescent haematology clinic","volume":"19","author":"Vo","year":"2013","journal-title":"Haemophilia"},{"key":"10.1016\/j.jpag.2013.06.003_bib5","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.1111\/j.1538-7836.2006.02146.x","article-title":"Working Party on von Willebrand Disease Classification: Update on the pathophysiology and classification of von Willebrand disease: a report of the Subcommittee on von Willebrand Factor","volume":"4","author":"Sadler","year":"2006","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.jpag.2013.06.003_bib6","doi-asserted-by":"crossref","first-page":"e223","DOI":"10.1111\/j.1365-2516.2010.02382.x","article-title":"The spectrum of haemostatic characteristics of women with unexplained menorrhagia","volume":"17","author":"Miller","year":"2011","journal-title":"Haemophilia"},{"key":"10.1016\/j.jpag.2013.06.003_bib7","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1046\/j.1538-7836.2003.00061.x","article-title":"Platelet functional defects in women with unexplained menorrhagia","volume":"1","author":"Philipp","year":"2003","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.jpag.2013.06.003_bib8","doi-asserted-by":"crossref","first-page":"357","DOI":"10.3324\/haematol.10816","article-title":"High prevalence of bleeders of unknown cause among patients with inherited mucocutaneous bleeding. A prospective study of 280 patients and 299 controls","volume":"92","author":"Quiroga","year":"2007","journal-title":"Haematologica"},{"key":"10.1016\/j.jpag.2013.06.003_bib9","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1111\/j.1479-828X.2005.00470.x","article-title":"Bleeding disorders in teenagers presenting with menorrhagia","volume":"45","author":"Jayasinghe","year":"2005","journal-title":"Aust N Z J Obstet Gynaecol"},{"key":"10.1016\/j.jpag.2013.06.003_bib10","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/0002-9378(81)90009-0","article-title":"Acute adolescent menorrhagia","volume":"139","author":"Claessens","year":"1981","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.jpag.2013.06.003_bib11","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1097\/01.AOG.0000148889.15061.fb","article-title":"Age and the prevalence of bleeding disorders in women with menorrhagia","volume":"105","author":"Philipp","year":"2005","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.jpag.2013.06.003_bib12","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1067\/mpd.2001.113042","article-title":"Bleeding disorders: A common cause of menorrhagia in adolescents","volume":"138","author":"Bevan","year":"2001","journal-title":"J Pediatr"},{"key":"10.1016\/j.jpag.2013.06.003_bib13","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1111\/j.1365-2516.2007.01496.x","article-title":"The prevalence of disorders of haemostasis in adolescents with menorrhagia referred to a haemophilia treatment centre","volume":"13","author":"Mikhail","year":"2007","journal-title":"Haemophilia"},{"key":"10.1016\/j.jpag.2013.06.003_bib14","first-page":"263","article-title":"American College of Obstetricians and Gynecologists: ACOG practice bulletin: management of anovulatory bleeding","volume":"72","author":"ACOG Committee on Practice Bulletins\u2013Gynecology","year":"2001","journal-title":"Int J Gynaecol"},{"key":"10.1016\/j.jpag.2013.06.003_bib15","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1097\/01.aids.0000299801.42415.8a","article-title":"Abnormal uterine bleeding: getting our terminology straight","volume":"19","author":"Fraser","year":"2007","journal-title":"Curr Opin Obstet Gynecol"},{"key":"10.1016\/j.jpag.2013.06.003_bib16","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.pedhc.2009.02.003","article-title":"Practice guideline: evaluation and management of abnormal vaginal bleeding in adolescents","volume":"23","author":"Benjamins","year":"2009","journal-title":"J Pediatr Health Care"},{"key":"10.1016\/j.jpag.2013.06.003_bib17","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1055\/s-0038-1661174","article-title":"Measurement of the bleeding time","volume":"52","author":"Mielke","year":"1984","journal-title":"Thromb Haemost"},{"key":"10.1016\/j.jpag.2013.06.003_bib18","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1182\/blood.V69.6.1691.1691","article-title":"The effect of ABO blood group on the diagnosis of von Willebrand disease","volume":"69","author":"Gill","year":"1987","journal-title":"Blood"},{"key":"10.1016\/j.jpag.2013.06.003_bib19","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1182\/blood.V75.7.1383.1383","article-title":"Glanzmann's thrombasthenia: the spectrum of clinical disease","volume":"75","author":"George","year":"1990","journal-title":"Blood"},{"key":"10.1016\/j.jpag.2013.06.003_bib20","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1515\/IJAMH.2004.16.2.183","article-title":"Coagulation disorders as the cause of menorrhagia in adolescents","volume":"16","author":"Kanbur","year":"2004","journal-title":"Int J Adolesc Med Health"},{"key":"10.1016\/j.jpag.2013.06.003_bib21","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1007\/s004040100192","article-title":"Hematological abnormalities in adolescent menorrhagia","volume":"266","author":"Oral","year":"2002","journal-title":"Arch Gynecol Obstet"},{"key":"10.1016\/j.jpag.2013.06.003_bib22","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S1083-3188(98)70101-9","article-title":"Menorrhagia in adolescents requiring hospitalization","volume":"11","author":"Smith","year":"1998","journal-title":"J Pediatr Adolesc Gynecol"},{"key":"10.1016\/j.jpag.2013.06.003_bib23","series-title":"Textbook of Hemophilia","first-page":"286","article-title":"Von Willebrand disease: epidemiology","author":"Rodeghiero","year":"2010"},{"key":"10.1016\/j.jpag.2013.06.003_bib24","series-title":"The Diagnosis, Evaluation, and Management of von Willebrand Disease, Publication No. 08-5832","author":"National Heart, Lung, and Blood Institute","year":"2007"},{"key":"10.1016\/j.jpag.2013.06.003_bib25","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1002\/ajh.2830400208","article-title":"On laboratory problems in diagnosing mild von Willebrand's disease","volume":"40","author":"Blomback","year":"1992","journal-title":"Am J Hematol"},{"key":"10.1016\/j.jpag.2013.06.003_bib26","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1055\/s-0037-1613140","article-title":"Changes in von Willebrand factor and\u00a0factor\u00a0VIII levels during the menstrual cycle","volume":"87","author":"Miller","year":"2002","journal-title":"Thromb Haemost"},{"issue":"6 Suppl","key":"10.1016\/j.jpag.2013.06.003_bib27","doi-asserted-by":"crossref","first-page":"S11","DOI":"10.1016\/j.jpag.2010.08.012","article-title":"Platelet disorders in adolescents","volume":"23","author":"Philipp","year":"2010","journal-title":"J Pediatr Adolesc Gynecol"},{"key":"10.1016\/j.jpag.2013.06.003_bib28","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.jpag.2012.01.004","article-title":"Platelet function disorders and menorrhagia in adolescents: a review of laboratory diagnosis","volume":"25","author":"Sokkary","year":"2012","journal-title":"J Pediatr Adolesc Gynecol"},{"key":"10.1016\/j.jpag.2013.06.003_bib29","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1097\/AOG.0b013e3181c6f975","article-title":"American College of Obstetricians and Gynecologists Committee Gynecologic Practice: ACOG Committee Opinion No. 451: Von Willebrand disease in women","volume":"114","author":"American College of Obstetricians and Gynecologists Committee on Adolescent Health Care","year":"2009","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.jpag.2013.06.003_bib30","doi-asserted-by":"crossref","first-page":"2515","DOI":"10.1182\/blood.V90.7.2515","article-title":"Desmopressin (DDAVP) in the treatment of bleeding disorders: the first 20 years","volume":"90","author":"Mannucci","year":"1997","journal-title":"Blood"},{"key":"10.1016\/j.jpag.2013.06.003_bib31","first-page":"117","article-title":"Evidence-based recommendations on the treatment of von Willebrand disease in Italy","volume":"7","author":"Mannucci","year":"2009","journal-title":"Blood Transfus"},{"key":"10.1016\/j.jpag.2013.06.003_bib32","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.jpag.2007.04.002","article-title":"Screening for coagulation disorders in adolescents with abnormal uterine bleeding","volume":"21","author":"Kulp","year":"2008","journal-title":"J Pediatr Adolesc Gynecol"}],"container-title":["Journal of Pediatric and Adolescent Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1083318813001885?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1083318813001885?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T13:40:32Z","timestamp":1761054032000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1083318813001885"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10]]},"references-count":32,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["S1083318813001885"],"URL":"https:\/\/doi.org\/10.1016\/j.jpag.2013.06.003","relation":{},"ISSN":["1083-3188"],"issn-type":[{"value":"1083-3188","type":"print"}],"subject":[],"published":{"date-parts":[[2013,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Prevalence of Hemostatic Disorders in Adolescents with Abnormal Uterine Bleeding","name":"articletitle","label":"Article Title"},{"value":"Journal of Pediatric and Adolescent Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpag.2013.06.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}