{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T13:23:37Z","timestamp":1788009817697,"version":"build-2784847793"},"reference-count":28,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,1]],"date-time":"2015-12-01T00:00:00Z","timestamp":1448928000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jpagonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pediatric and Adolescent Gynecology"],"published-print":{"date-parts":[[2015,12]]},"DOI":"10.1016\/j.jpag.2015.01.002","type":"journal-article","created":{"date-parts":[[2015,1,7]],"date-time":"2015-01-07T11:56:11Z","timestamp":1420631771000},"page":"457-461","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":59,"title":["Effect of Dietary Weight Loss on Menstrual Regularity in Obese Young Adult Women with Polycystic Ovary Syndrome"],"prefix":"10.1016","volume":"28","author":[{"given":"Tayseer M.","family":"Marzouk","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Waleed A.","family":"Sayed Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpag.2015.01.002_bib1","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1210\/jc.2005-1994","article-title":"Early effects of metformin in women with polycystic ovary syndrome: a prospective randomized, double blind, placebo-controlled trial","volume":"91","author":"Eisenhardt","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpag.2015.01.002_bib2","first-page":"403","article-title":"Chronic anovulation syndrome and associated neoplasia","volume":"61","author":"Coulam","year":"1983","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.jpag.2015.01.002_bib3","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1210\/jc.2002-020815","article-title":"Dietary composition in restoring reproductive and metabolic physiology in overweight women with polycystic ovary syndrome","volume":"88","author":"Moran","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpag.2015.01.002_bib4","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1093\/ajcn\/84.1.77","article-title":"Short-term meal replacements followed by dietary macronutrient restriction enhance weight loss in polycystic ovary syndrome","volume":"84","author":"Moran","year":"2006","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.jpag.2015.01.002_bib5","doi-asserted-by":"crossref","first-page":"3970","DOI":"10.1210\/jc.2005-2250","article-title":"Treatment with flutamide, metformin, and their combination added to a hypocaloric diet in overweight-obese women with polycystic ovary syndrome: a randomized, 12-month, placebo-controlled study","volume":"91","author":"Gambineri","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpag.2015.01.002_bib6","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1016\/j.fertnstert.2003.08.023","article-title":"A randomized trial of the effects of two types of short-term hypocaloric diets on weight loss in women with polycystic ovary syndrome","volume":"81","author":"Stamets","year":"2004","journal-title":"Fertil Steril"},{"key":"10.1016\/j.jpag.2015.01.002_bib7","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.fertnstert.2004.02.104","article-title":"A randomized, 48-week, placebo-controlled trial of intensive lifestyle modification and\/or metformin therapy in overweight women with polycystic ovary syndrome: a pilot study","volume":"82","author":"Hoeger","year":"2004","journal-title":"Fertil Steril"},{"key":"10.1016\/j.jpag.2015.01.002_bib8","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1111\/j.1365-2265.1992.tb02909.x","article-title":"Improvement in endocrine and ovarian function during dietary treatment of obese women with polycystic ovary syndrome","volume":"36","author":"Kiddy","year":"1992","journal-title":"Clin Endocrinol (Oxf)"},{"key":"10.1016\/j.jpag.2015.01.002_bib9","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.jpag.2011.01.002","article-title":"Effect of weight loss on menstrual function in adolescents with polycystic ovary syndrome","volume":"24","author":"Ornstein","year":"2011","journal-title":"J Pediatr Adolesc Gynecol"},{"key":"10.1016\/j.jpag.2015.01.002_bib10","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1093\/ajcn\/40.1.168","article-title":"The Harris Benedict equation reevaluated","volume":"40","author":"Roza","year":"1984","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.jpag.2015.01.002_bib11","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/j.jand.2012.11.018","article-title":"Dietary composition in the treatment of polycystic ovary syndrome: a systematic review to inform evidence-based guidelines","volume":"113","author":"Moran","year":"2013","journal-title":"J Acad Nutr Diet"},{"key":"10.1016\/j.jpag.2015.01.002_bib12","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1016\/S0002-8223(21)03818-9","article-title":"Validity of the 24-hour dietary recall","volume":"85","author":"Karvetti","year":"1985","journal-title":"J Am Diet Assoc"},{"key":"10.1016\/j.jpag.2015.01.002_bib13","series-title":"Obesity: preventing and managing the global epidemic: report of a WHO convention, Geneva 1999 (WHO technical report series 894)","author":"World Health Organization","year":"2000"},{"key":"10.1016\/j.jpag.2015.01.002_bib14","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1210\/jcem-21-11-1440","article-title":"Clinical assessment of body hair growth in women","volume":"21","author":"Ferriman","year":"1961","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpag.2015.01.002_bib15","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1038\/sj.ijo.0801994","article-title":"Obesity and the polycystic ovary syndrome","volume":"26","author":"Gambineri","year":"2002","journal-title":"Int J Obes Relat Metab Disord"},{"key":"10.1016\/j.jpag.2015.01.002_bib16","first-page":"97","article-title":"Polycystic ovary syndrome. Long term sequelae and management","volume":"54","author":"Legro","year":"2002","journal-title":"Minerva Ginecol"},{"key":"10.1016\/j.jpag.2015.01.002_bib17","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/S1054-139X(01)00202-6","article-title":"Metformin to restore normal menses in oligo-amenorrheic teenage girls with polycystic ovary syndrome (PCOS)","volume":"29","author":"Glueck","year":"2001","journal-title":"J\u00a0Adolesc Health"},{"key":"10.1016\/j.jpag.2015.01.002_bib18","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1515\/JPEM.2006.19.6.831","article-title":"Metformin-diet ameliorates coronary heart disease risk factors and facilitates resumption of regular menses in adolescents with polycystic ovary syndrome","volume":"19","author":"Glueck","year":"2006","journal-title":"J Pediatr Endocrinol Metab"},{"key":"10.1016\/j.jpag.2015.01.002_bib19","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1515\/JPEM.2009.22.9.815","article-title":"Metformin-diet ameliorates coronary heart disease risk factors and facilitates resumption of regular menses in adolescents with polycystic ovary syndrome","volume":"22","author":"Glueck","year":"2009","journal-title":"J Pediatr Endocrinol Metab"},{"key":"10.1016\/j.jpag.2015.01.002_bib20","doi-asserted-by":"crossref","first-page":"3533","DOI":"10.1210\/jc.2011-1609","article-title":"Effect of lifestyle intervention on features of polycystic ovarian syndrome, metabolic syndrome, and intima-media thickness in obese adolescent girls","volume":"96","author":"Lass","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpag.2015.01.002_bib21","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1186\/1743-7075-2-35","article-title":"The effects of a low-carbohydrate, ketogenic diet on the polycystic ovary syndrome: a pilot study","volume":"16","author":"Mavropoulos","year":"2005","journal-title":"Nutr Metab (Lond)"},{"key":"10.1016\/j.jpag.2015.01.002_bib22","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.fertnstert.2005.08.045","article-title":"Role of diet in the treatment of polycystic ovary syndrome","volume":"85","author":"Douglas","year":"2006","journal-title":"Fertil Steril"},{"key":"10.1016\/j.jpag.2015.01.002_bib23","doi-asserted-by":"crossref","first-page":"83","DOI":"10.3945\/ajcn.2010.29261","article-title":"Effect of a low glycemic index compared with a conventional healthy diet on polycystic ovary syndrome","volume":"92","author":"Marsh","year":"2010","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.jpag.2015.01.002_bib24","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.dsx.2013.10.005","article-title":"Adiponectin and waist circumference as predictors of insulin-resistance in women","volume":"8","author":"Bonneau","year":"2014","journal-title":"Diabetes Metab Syndr"},{"key":"10.1016\/j.jpag.2015.01.002_bib25","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1210\/jcem.87.2.8261","article-title":"Ovarian function and metabolic factors in women with oligomenorrhea treated with metformin in a randomized double blind, placebo controlled fashion","volume":"87","author":"Fleming","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpag.2015.01.002_bib26","first-page":"3299","article-title":"The insulin sensitizing agent troglitazone improves metabolic and reproductive abnormalities in the polycystic ovary syndrome","volume":"81","author":"Dunaif","year":"1996","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.jpag.2015.01.002_bib27","doi-asserted-by":"crossref","first-page":"2082","DOI":"10.1056\/NEJMoa022207","article-title":"A randomized trial of a low-carbohydrate diet for obesity","volume":"348","author":"Foster","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jpag.2015.01.002_bib28","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/j.fertnstert.2011.09.024","article-title":"Consensus on women's health aspects\u00a0of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE\/ASRM-Sponsored 3rd PCOS Consensus Workshop Group","volume":"97","author":"Fauser","year":"2012","journal-title":"Fertil Steril"}],"container-title":["Journal of Pediatric and Adolescent Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1083318815000030?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1083318815000030?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T13:42:05Z","timestamp":1761054125000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1083318815000030"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,12]]}},"alternative-id":["S1083318815000030"],"URL":"https:\/\/doi.org\/10.1016\/j.jpag.2015.01.002","relation":{},"ISSN":["1083-3188"],"issn-type":[{"value":"1083-3188","type":"print"}],"subject":[],"published":{"date-parts":[[2015,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of Dietary Weight Loss on Menstrual Regularity in Obese Young Adult Women with Polycystic Ovary Syndrome","name":"articletitle","label":"Article Title"},{"value":"Journal of Pediatric and Adolescent Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpag.2015.01.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}