{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T16:16:55Z","timestamp":1787242615169,"version":"build-2736575974"},"reference-count":10,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jpagonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pediatric and Adolescent Gynecology"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.jpag.2025.06.001","type":"journal-article","created":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T19:29:24Z","timestamp":1749497364000},"page":"637-639","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["A Case Report of Primary Ovarian Failure in an Adolescent Associated With a Homozygous Pathogenic Variant in the Mitochondrial Poly-A-Polymerase Gene (MTPAP)"],"prefix":"10.1016","volume":"38","author":[{"given":"Jessy","family":"Epstein","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simrat","family":"Veera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Pappas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bina Cherryl","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.jpag.2025.06.001_bib0001","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.fertnstert.2024.11.007","article-title":"Evidence-based guideline: premature ovarian insufficiency","volume":"123","author":"Panay","year":"2025","journal-title":"Fertil Steril"},{"issue":"10","key":"10.1016\/j.jpag.2025.06.001_bib0002","doi-asserted-by":"crossref","first-page":"2353","DOI":"10.1210\/en.2019-00441","article-title":"Mitochondrial dysfunction in primary ovarian insufficiency","volume":"160","author":"Tiosano","year":"2019","journal-title":"Endocrinology"},{"issue":"1-2","key":"10.1016\/j.jpag.2025.06.001_bib0003","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.mce.2013.04.014","article-title":"Steroid hormone synthesis in mitochondria","volume":"379","author":"Miller","year":"2013","journal-title":"Mol Cell Endocrinol"},{"issue":"6","key":"10.1016\/j.jpag.2025.06.001_bib0004","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1016\/j.rbmo.2018.02.007","article-title":"The role of mitochondrial activity in female fertility and assisted reproductive technologies: overview and current insights","volume":"36","author":"Cecchino","year":"2018","journal-title":"Reprod Biomed Online"},{"key":"10.1016\/j.jpag.2025.06.001_bib0005","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.23908","article-title":"Mitochondrial flashes regulate ATP homeostasis in the heart","volume":"6","author":"Wang","year":"2017","journal-title":"Elife"},{"issue":"15","key":"10.1016\/j.jpag.2025.06.001_bib0006","doi-asserted-by":"crossref","first-page":"7999","DOI":"10.3390\/ijms22157999","article-title":"Human mitochondrial RNA processing and modifications: overview","volume":"22","author":"Jedynak-Slyvka","year":"2021","journal-title":"Int J Mol Sci"},{"issue":"20","key":"10.1016\/j.jpag.2025.06.001_bib0007","doi-asserted-by":"crossref","first-page":"6001","DOI":"10.1093\/nar\/gkh923","article-title":"Identification of a novel human nuclear-encoded mitochondrial poly(A) polymerase","volume":"32","author":"Tomecki","year":"2004","journal-title":"Nucleic Acids Res"},{"issue":"23","key":"10.1016\/j.jpag.2025.06.001_bib0008","doi-asserted-by":"crossref","first-page":"6345","DOI":"10.1093\/hmg\/ddu352","article-title":"A human mitochondrial poly(A) polymerase mutation reveals the complexities of post-transcriptional mitochondrial gene expression","volume":"23","author":"Wilson","year":"2014","journal-title":"Hum Mol Genet"},{"issue":"5","key":"10.1016\/j.jpag.2025.06.001_bib0009","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.ajhg.2010.09.013","article-title":"Defective mitochondrial mRNA maturation is associated with spastic ataxia","volume":"87","author":"Crosby","year":"2010","journal-title":"Am J Hum Genet"},{"issue":"3","key":"10.1016\/j.jpag.2025.06.001_bib0010","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1055\/s-0039-3400979","article-title":"Biallelic mutations in MTPAP associated with a lethal encephalopathy","volume":"51","author":"Van Eyck","year":"2020","journal-title":"Neuropediatrics"}],"container-title":["Journal of Pediatric and Adolescent Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1083318825002736?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1083318825002736?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T13:59:19Z","timestamp":1757771959000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1083318825002736"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["S1083318825002736"],"URL":"https:\/\/doi.org\/10.1016\/j.jpag.2025.06.001","relation":{},"ISSN":["1083-3188"],"issn-type":[{"value":"1083-3188","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A Case Report of Primary Ovarian Failure in an Adolescent Associated With a Homozygous Pathogenic Variant in the Mitochondrial Poly-A-Polymerase Gene (MTPAP)","name":"articletitle","label":"Article Title"},{"value":"Journal of Pediatric and Adolescent Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpag.2025.06.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}