{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T10:51:32Z","timestamp":1776768692667,"version":"3.51.2"},"reference-count":14,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T00:00:00Z","timestamp":1754956800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jpagonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pediatric and Adolescent Gynecology"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.jpag.2025.08.002","type":"journal-article","created":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T22:26:43Z","timestamp":1755037603000},"page":"754-758","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Virilization and Hyperandrogenism in Turner Syndrome without Y Mosaicism: A Case Report and Review of the Literature"],"prefix":"10.1016","volume":"38","author":[{"given":"Jacquelyn R.","family":"Evans","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer M.","family":"Ladd","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miriam R.","family":"Conces","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott E.","family":"Hickey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel C.","family":"Koboldt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yueyang Frances","family":"Fei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.jpag.2025.08.002_bib0001","doi-asserted-by":"crossref","first-page":"G53","DOI":"10.1093\/ejendo\/lvae050","article-title":"Clinical practice guidelines for the care of girls and women with Turner syndrome","volume":"190","author":"Gravholt","year":"2024","journal-title":"Eur J Endocrinol"},{"issue":"1-02","key":"10.1016\/j.jpag.2025.08.002_bib0002","first-page":"42","article-title":"Non-PCOS hyperandrogenic disorders in adolescents","volume":"40","author":"Esquivel-Zuniga","year":"2022","journal-title":"Semin Reprod Med"},{"issue":"10","key":"10.1016\/j.jpag.2025.08.002_bib0003","article-title":"Oxandrolone for growth hormone-treated girls aged up to 18 years with Turner syndrome","volume":"2019","author":"Mohamed","year":"2019","journal-title":"Cochrane Database Syst Rev"},{"issue":"3","key":"10.1016\/j.jpag.2025.08.002_bib0004","first-page":"338","article-title":"Virilizing ovarian hilus (Leydig) cell tumor with concurrent contralateral hilus cell hyperplasia: a rare diagnosis","volume":"30","author":"Zafrakas","year":"2009","journal-title":"Eur J Gynaecol Oncol"},{"key":"10.1016\/j.jpag.2025.08.002_bib0005","article-title":"Bilateral Leydig cell hyperplasia: a rare cause of postmenopausal hirsutism","volume":"2022","author":"Pathmanathan","year":"2022","journal-title":"Case Rep Endocrinol"},{"key":"10.1016\/j.jpag.2025.08.002_bib0006","article-title":"Leydig tumor in normal sized ovaries causing clitoromegaly: a case report","volume":"52","author":"Chavez","year":"2024","journal-title":"Gynecol Oncol Rep"},{"issue":"4","key":"10.1016\/j.jpag.2025.08.002_bib0007","first-page":"490","article-title":"Virilization in Turner syndrome","volume":"52","author":"Fayez","year":"1978","journal-title":"Obstet Gynecol"},{"issue":"7","key":"10.1016\/j.jpag.2025.08.002_bib0008","doi-asserted-by":"crossref","first-page":"2430.e7","DOI":"10.1016\/j.fertnstert.2011.03.068","article-title":"Ovarian hilus cell hyperplasia as the cause of virilization in 45,X Turner\u2019s syndrome","volume":"95","author":"Damle","year":"2011","journal-title":"Fertil Steril"},{"issue":"5","key":"10.1016\/j.jpag.2025.08.002_bib0009","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1210\/js.2018-00017","article-title":"Hepatocellular carcinoma, virilization, and hilus cell hyperplasia in a girl with Turner syndrome","volume":"2","author":"Law","year":"2018","journal-title":"J Endocr Soc"},{"issue":"7325","key":"10.1016\/j.jpag.2025.08.002_bib0010","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0140-6736(64)92225-1","article-title":"Hilus-cell adenoma in a dysgenetic gonad with XX\/XO mosaicism","volume":"1","author":"Warren","year":"1964","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.jpag.2025.08.002_bib0011","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1046\/j.1365-2265.1999.00607.x","article-title":"Y-chromosome identification by PCR and gonadal histopathology in Turner\u2019s syndrome without overt Y-mosaicism","volume":"50","author":"Mendes","year":"1999","journal-title":"Clin Endocrinol (Oxf)"},{"issue":"2","key":"10.1016\/j.jpag.2025.08.002_bib0012","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1111\/j.1471-0528.1980.tb04512.x","article-title":"A virilizing hilus-cell tumour in an African patient with Turner\u2019s syndrome","volume":"87","author":"Lyons","year":"1980","journal-title":"Br J Obstet Gynaecol"},{"issue":"4","key":"10.1016\/j.jpag.2025.08.002_bib0013","doi-asserted-by":"crossref","first-page":"e279","DOI":"10.1097\/AOG.0000000000003164","article-title":"ACOG Committee Opinion No. 774: opportunistic salpingectomy as a strategy for epithelial ovarian cancer prevention","volume":"133","year":"2019","journal-title":"Obstet Gynecol"},{"issue":"10","key":"10.1016\/j.jpag.2025.08.002_bib0014","doi-asserted-by":"crossref","first-page":"bvac127","DOI":"10.1210\/jendso\/bvac127","article-title":"Precocious puberty in a boy with bilateral Leydig cell tumors due to a somatic gain-of-function LHCGR variant","volume":"6","author":"Flippo","year":"2022","journal-title":"J Endocr Soc"}],"container-title":["Journal of Pediatric and Adolescent Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1083318825003237?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1083318825003237?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T03:43:46Z","timestamp":1763696626000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1083318825003237"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":14,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["S1083318825003237"],"URL":"https:\/\/doi.org\/10.1016\/j.jpag.2025.08.002","relation":{},"ISSN":["1083-3188"],"issn-type":[{"value":"1083-3188","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Virilization and Hyperandrogenism in Turner Syndrome without Y Mosaicism: A Case Report and Review of the Literature","name":"articletitle","label":"Article Title"},{"value":"Journal of Pediatric and Adolescent Gynecology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpag.2025.08.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc. on behalf of North American Society for Pediatric and Adolescent Gynecology.","name":"copyright","label":"Copyright"}]}}