{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,4]],"date-time":"2026-03-04T06:15:57Z","timestamp":1772604957018,"version":"3.50.1"},"reference-count":35,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2008,7,1]],"date-time":"2008-07-01T00:00:00Z","timestamp":1214870400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2008,7,1]],"date-time":"2008-07-01T00:00:00Z","timestamp":1214870400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T00:00:00Z","timestamp":1694390400000},"content-version":"vor","delay-in-days":5550,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jpain.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pain"],"published-print":{"date-parts":[[2008,7]]},"DOI":"10.1016\/j.jpain.2008.02.003","type":"journal-article","created":{"date-parts":[[2008,4,16]],"date-time":"2008-04-16T09:41:46Z","timestamp":1208338906000},"page":"658-665","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Widespread Unilateral Pain Associated With Herpes Simplex Virus Infections"],"prefix":"10.1016","volume":"9","author":[{"given":"Katariina","family":"Kallio-Laine","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikko","family":"Sepp\u00e4nen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marja-Liisa","family":"Lokki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maija","family":"Lappalainen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irma-Leena","family":"Notkola","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilkka","family":"Sepp\u00e4l\u00e4","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mika","family":"Koskinen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ville","family":"Valtonen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eija","family":"Kalso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpain.2008.02.003_bib1","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1034\/j.1399-0039.2000.560302.x","article-title":"Prospective analysis suggests susceptibility genes for deficiencies of IgA and several other immunoglobulins on the [HLA-B8, SC01, DR3] conserved extended haplotype","volume":"56","author":"Alper","year":"2000","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.jpain.2008.02.003_bib2","doi-asserted-by":"crossref","first-page":"2181","DOI":"10.1056\/NEJMcpc049005","article-title":"Case 16-2004: A 76 year old woman with numbness and pain in the feet and legs","volume":"350","author":"Amato","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jpain.2008.02.003_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.pain.2006.03.001","article-title":"Mediation of chronic pain: Not by neurons alone","volume":"124","author":"Banks","year":"2006","journal-title":"Pain"},{"key":"10.1016\/j.jpain.2008.02.003_bib4","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/S1567-5769(01)00019-4","article-title":"Genetic, structural and functional diversities of human complement components C4A and C4B and their mouse homologues, Slp and C4","volume":"1","author":"Blanchong","year":"2001","journal-title":"Int Immunopharmacol"},{"key":"10.1016\/j.jpain.2008.02.003_bib5","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1146\/annurev.med.54.101601.152346","article-title":"The influence of HLA genotype on AIDS","volume":"54","author":"Carrington","year":"2003","journal-title":"Annu Rev Med"},{"key":"10.1016\/j.jpain.2008.02.003_bib6","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1056\/NEJM197811022991805","article-title":"Cellular immune response in genital herpes simplex virus infection","volume":"299","author":"Corey","year":"1978","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jpain.2008.02.003_bib7","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1056\/NEJM200003023420906","article-title":"Neurologic complications of the reactivation of varicella-zoster virus","volume":"342","author":"Gilden","year":"2000","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jpain.2008.02.003_bib8","series-title":"CRPS: Current Diagnosis and Therapy","first-page":"45","article-title":"Diagnostic criteria: The statistical derivation of the four criterion factors","author":"Harden","year":"2005"},{"key":"10.1016\/j.jpain.2008.02.003_bib9","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1128\/CMR.16.1.96-113.2003","article-title":"Recent progress in herpes simplex virus immunobiology and vaccine research","volume":"16","author":"Koelle","year":"2003","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.jpain.2008.02.003_bib10","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1086\/315208","article-title":"Limited antibody-dependent cellular cytotoxicity antibody response induced by a herpes simplex virus type 2 subunit vaccine","volume":"181","author":"Kohl","year":"2000","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jpain.2008.02.003_bib11","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1007\/s00415-005-0743-x","article-title":"A quantitative method for the assessment of intraepidermal nerve fibers in small-fiber neuropathy","volume":"252","author":"Koskinen","year":"2005","journal-title":"J Neurol"},{"key":"10.1016\/j.jpain.2008.02.003_bib12","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1002\/mus.10181","article-title":"Small-fiber neuropathy","volume":"26","author":"Lacomis","year":"2002","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.jpain.2008.02.003_bib13","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1086\/314729","article-title":"Association of major histocompatibility complex determinants with the development of symptomatic and asymptomatic genital herpes simplex virus type 2 infections","volume":"179","author":"Lekstrom-Himes","year":"1999","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jpain.2008.02.003_bib14","author":"Lokki"},{"key":"10.1016\/j.jpain.2008.02.003_bib15","doi-asserted-by":"crossref","first-page":"S30","DOI":"10.1212\/WNL.62.5_suppl_2.S30","article-title":"Evaluation and treatment of central pain syndromes","volume":"62","author":"Nicholson","year":"2004","journal-title":"Neurology"},{"key":"10.1016\/j.jpain.2008.02.003_bib16","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.pain.2005.09.036","article-title":"Evidence of focal small fiber axonal degeneration in complex regional pain syndrome","volume":"120","author":"Oaklander","year":"2006","journal-title":"Pain"},{"key":"10.1016\/j.jpain.2008.02.003_bib17","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1034\/j.1600-065X.2000.17815.x","article-title":"Molecular basis of IgG subclass deficiency","volume":"178","author":"Pan","year":"2000","journal-title":"Immunol Rev"},{"key":"10.1016\/j.jpain.2008.02.003_bib18","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1136\/sti.2003.005850","article-title":"The seroepidemiology of herpes simplex virus type 1 and 2 in Europe","volume":"80","author":"Pebody","year":"2004","journal-title":"Sex Transm Infect"},{"key":"10.1016\/j.jpain.2008.02.003_bib19","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1002\/glia.20560","article-title":"Microglial GLT-1 is upregulated in response to herpes simplex virus infection to provide an antiviral defence via glutathione","volume":"55","author":"Persson","year":"2007","journal-title":"Glia"},{"key":"10.1016\/j.jpain.2008.02.003_bib20","doi-asserted-by":"crossref","first-page":"11990","DOI":"10.1128\/JVI.79.18.11990-12001.2005","article-title":"The extracellular domain of herpes simplex virus gE is indispensable for efficient cell-to-cell spread: Evidence for gE\/gI receptors","volume":"79","author":"Polcicova","year":"2005","journal-title":"J Virol"},{"key":"10.1016\/j.jpain.2008.02.003_bib21","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1038\/sj.mp.4001915","article-title":"Brain morphological changes associated with exposure to HSV1 in first-episode schizophrenia","volume":"12","author":"Prasad","year":"2007","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.jpain.2008.02.003_bib22","first-page":"369","article-title":"Herpes latency, meningitis, radiculomyelopathy and disseminated infection","volume":"70","author":"Sasadeusz","year":"1994","journal-title":"Genitourin Med"},{"key":"10.1016\/j.jpain.2008.02.003_bib23","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1097\/00000542-200605000-00024","article-title":"Major histocompatibility complex haplotype is associated with postherpetic pain in mice","volume":"104","author":"Sato-Takeda","year":"2006","journal-title":"Anesthesiology"},{"key":"10.1016\/j.jpain.2008.02.003_bib24","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1097\/01.wco.0000236620.89710.63","article-title":"Imaging pain in patients: Is it meaningful?","volume":"19","author":"Schweinhardt","year":"2006","journal-title":"Curr Opin Neurol"},{"key":"10.1016\/j.jpain.2008.02.003_bib25","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1097\/00007611-198411000-00032","article-title":"Polyneuropathy after herpes simplex type 2 meningitis","volume":"77","author":"Seibert","year":"1984","journal-title":"South Med J"},{"key":"10.1016\/j.jpain.2008.02.003_bib26","doi-asserted-by":"crossref","first-page":"2529","DOI":"10.4049\/jimmunol.151.5.2529","article-title":"Low concentrations of Gm allotypic subsets G3 mg and G1 mf in homozygotes and heterozygotes","volume":"151","author":"Seppala","year":"1993","journal-title":"J Immunol"},{"key":"10.1016\/j.jpain.2008.02.003_bib27","doi-asserted-by":"crossref","first-page":"1604","DOI":"10.1086\/323462","article-title":"Complement C4 deficiency and HLA homozygosity in patients with frequent intraoral herpes simplex virus type 1 infections","volume":"33","author":"Seppanen","year":"2001","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.jpain.2008.02.003_bib28","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1086\/506477","article-title":"Subtly impaired humoral immunity predisposes to frequently recurring genital herpes simplex virus type 2 infection and herpetic neuralgia","volume":"194","author":"Seppanen","year":"2006","journal-title":"J Infect Dis"},{"key":"10.1016\/j.jpain.2008.02.003_bib29","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1111\/j.1399-0039.2004.00327.x","article-title":"An update of the HLA genomic region, locus information and disease associations: 2004","volume":"64","author":"Shiina","year":"2004","journal-title":"Tissue Antigens"},{"key":"10.1016\/j.jpain.2008.02.003_bib30","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1038\/sj.gene.6364362","article-title":"Non-B27 MHC associations of ankylosing spondylitis","volume":"8","author":"Sims","year":"2007","journal-title":"Genes Immunol"},{"key":"10.1016\/j.jpain.2008.02.003_bib31","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1189\/jlb.0403128","article-title":"Fcgamma receptor signaling in primary human microglia: Differential roles of PI-3K and Ras\/ERK MAPK pathways in phagocytosis and chemokine induction","volume":"75","author":"Song","year":"2004","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.jpain.2008.02.003_bib32","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.brainresrev.2007.06.006","article-title":"\u201cListening\u201d and \u201ctalking\u201d to neurons: Implications of immune activation for pain control and increasing the efficacy of opioids","volume":"56","author":"Watkins","year":"2007","journal-title":"Brain Research Reviews"},{"key":"10.1016\/j.jpain.2008.02.003_bib33","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1016\/S0140-6736(00)04638-9","article-title":"Herpes simplex virus infections","volume":"357","author":"Whitley","year":"2001","journal-title":"Lancet"},{"key":"10.1016\/j.jpain.2008.02.003_bib34","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.neuint.2003.09.009","article-title":"Glial activation and pathological pain","volume":"45","author":"Wieseler-Frank","year":"2004","journal-title":"Neurochem Int"},{"key":"10.1016\/j.jpain.2008.02.003_bib35","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1136\/jnnp.74.2.262","article-title":"Relapsing herpes simplex encephalitis: Pathological confirmation of viral reactivation","volume":"74","author":"Yamada","year":"2003","journal-title":"J Neurol Neurosurg Psychiatry"}],"container-title":["The Journal of Pain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1526590008004197?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1526590008004197?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T19:45:58Z","timestamp":1761507958000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1526590008004197"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,7]]},"references-count":35,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2008,7]]}},"alternative-id":["S1526590008004197"],"URL":"https:\/\/doi.org\/10.1016\/j.jpain.2008.02.003","relation":{},"ISSN":["1526-5900"],"issn-type":[{"value":"1526-5900","type":"print"}],"subject":[],"published":{"date-parts":[[2008,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Widespread Unilateral Pain Associated With Herpes Simplex Virus Infections","name":"articletitle","label":"Article Title"},{"value":"The Journal of Pain","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpain.2008.02.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2008 American Pain Society. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}