{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T06:15:45Z","timestamp":1771481745484,"version":"3.50.1"},"reference-count":57,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2016,4,1]],"date-time":"2016-04-01T00:00:00Z","timestamp":1459468800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T00:00:00Z","timestamp":1694390400000},"content-version":"vor","delay-in-days":2719,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","jpain.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pain"],"published-print":{"date-parts":[[2016,4]]},"DOI":"10.1016\/j.jpain.2015.12.007","type":"journal-article","created":{"date-parts":[[2015,12,22]],"date-time":"2015-12-22T10:56:07Z","timestamp":1450781767000},"page":"444-450","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Role of Kv4.3 in Vibration-Induced Muscle Pain in the Rat"],"prefix":"10.1016","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2756-1233","authenticated-orcid":false,"given":"Lindsay B.","family":"Conner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Alvarez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oliver","family":"Bogen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jon D.","family":"Levine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpain.2015.12.007_bib1","doi-asserted-by":"crossref","first-page":"2077","DOI":"10.1152\/jn.1992.68.6.2077","article-title":"Increased responsiveness of sensory neurons in the saphenous nerve of the streptozotocin-diabetic rat","volume":"68","author":"Ahlgren","year":"1992","journal-title":"J Neurophysiol"},{"key":"10.1016\/j.jpain.2015.12.007_bib2","doi-asserted-by":"crossref","first-page":"4680","DOI":"10.1523\/JNEUROSCI.20-12-04680.2000","article-title":"Chronic hypersensitivity for inflammatory nociceptor sensitization mediated by the epsilon isozyme of protein kinase C","volume":"20","author":"Aley","year":"2000","journal-title":"J Neurosci"},{"key":"10.1016\/j.jpain.2015.12.007_bib3","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.1152\/jn.00576.2012","article-title":"IB4(+) nociceptors mediate persistent muscle pain induced by GDNF","volume":"108","author":"Alvarez","year":"2012","journal-title":"J Neurophysiol"},{"key":"10.1016\/j.jpain.2015.12.007_bib4","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/j.expneurol.2011.12.019","article-title":"IB4-saporin attenuates acute and eliminates chronic muscle pain in the rat","volume":"233","author":"Alvarez","year":"2012","journal-title":"Exp Neurol"},{"key":"10.1016\/j.jpain.2015.12.007_bib5","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1016\/j.pain.2014.03.004","article-title":"Role for monocyte chemoattractant protein-1 in the induction of chronic muscle pain in the rat","volume":"155","author":"Alvarez","year":"2014","journal-title":"Pain"},{"key":"10.1016\/j.jpain.2015.12.007_bib6","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1111\/j.1460-9568.2010.07359.x","article-title":"Eccentric exercise induces chronic alterations in musculoskeletal nociception in the rat","volume":"32","author":"Alvarez","year":"2010","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.jpain.2015.12.007_bib7","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1002\/cne.10655","article-title":"Chemical phenotypes of muscle and cutaneous afferent neurons in the rat trigeminal ganglion","volume":"460","author":"Ambalavanar","year":"2003","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.jpain.2015.12.007_bib8","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.cell.2009.09.028","article-title":"Cellular and molecular mechanisms of pain","volume":"139","author":"Basbaum","year":"2009","journal-title":"Cell"},{"key":"10.1016\/j.jpain.2015.12.007_bib9","doi-asserted-by":"crossref","first-page":"2018","DOI":"10.1523\/JNEUROSCI.5138-11.2012","article-title":"Generation of a pain memory in the primary afferent nociceptor triggered by PKC\u03b5 activation of CPEB","volume":"32","author":"Bogen","year":"2012","journal-title":"J Neurosci"},{"key":"10.1016\/j.jpain.2015.12.007_bib10","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1111\/jnc.13113","article-title":"Neuronally produced versican V2 renders C-fiber nociceptors IB4 -positive","volume":"134","author":"Bogen","year":"2015","journal-title":"J Neurochem"},{"key":"10.1016\/j.jpain.2015.12.007_bib11","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1016\/j.neuroscience.2008.12.049","article-title":"Dependence of monocyte chemoattractant protein 1 induced hyperalgesia on the isolectin B4-binding protein versican","volume":"159","author":"Bogen","year":"2009","journal-title":"Neuroscience"},{"key":"10.1016\/j.jpain.2015.12.007_bib12","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1111\/j.1460-9568.2008.06308.x","article-title":"GDNF hyperalgesia is mediated by PLCgamma, MAPK\/ERK, PI3K, CDK5 and Src family kinase signaling and dependent on the IB4-binding protein versican","volume":"28","author":"Bogen","year":"2008","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.jpain.2015.12.007_bib13","doi-asserted-by":"crossref","first-page":"2112","DOI":"10.1523\/JNEUROSCI.23-06-02112.2003","article-title":"Ischemic insults derepress the gene silencer REST in neurons destined to die","volume":"23","author":"Calderone","year":"2003","journal-title":"J Neurosci"},{"key":"10.1016\/j.jpain.2015.12.007_bib14","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1111\/j.1471-4159.2010.06863.x","article-title":"Reduction in voltage-gated K+ channel activity in primary sensory neurons in painful diabetic neuropathy: role of brain-derived neurotrophic factor","volume":"114","author":"Cao","year":"2010","journal-title":"J Neurochem"},{"key":"10.1016\/j.jpain.2015.12.007_bib15","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.pain.2010.08.004","article-title":"Neuropathic pain-like alterations in muscle nociceptor function associated with vibration-induced muscle pain","volume":"151","author":"Chen","year":"2010","journal-title":"Pain"},{"key":"10.1016\/j.jpain.2015.12.007_bib16","doi-asserted-by":"crossref","first-page":"9855","DOI":"10.1523\/JNEUROSCI.0604-07.2007","article-title":"Reduced expression of A-type potassium channels in primary sensory neurons induces mechanical hypersensitivity","volume":"27","author":"Chien","year":"2007","journal-title":"J Neurosci"},{"key":"10.1016\/j.jpain.2015.12.007_bib17","doi-asserted-by":"crossref","first-page":"f7656","DOI":"10.1136\/bmj.f7656","article-title":"Neuropathic pain: Mechanisms and their clinical implications","volume":"348","author":"Cohen","year":"2014","journal-title":"BMJ"},{"key":"10.1016\/j.jpain.2015.12.007_bib18","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1093\/bja\/aeu323","article-title":"Peripheral neuropathic pain: Signs, symptoms, mechanisms, and causes: Are they linked","volume":"114","author":"Colvin","year":"2015","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.jpain.2015.12.007_bib19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1146\/annurev.neuro.051508.135531","article-title":"Neuropathic pain: A maladaptive response of the nervous system to damage","volume":"32","author":"Costigan","year":"2009","journal-title":"Annu Rev Neurosci"},{"key":"10.1016\/j.jpain.2015.12.007_bib20","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.neuroscience.2008.01.006","article-title":"Role of interleukin-6 in chronic muscle hyperalgesic priming","volume":"152","author":"Dina","year":"2008","journal-title":"Neuroscience"},{"key":"10.1016\/j.jpain.2015.12.007_bib21","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.jpain.2009.08.007","article-title":"Mechanisms mediating vibration-induced chronic musculoskeletal pain analyzed in the rat","volume":"11","author":"Dina","year":"2010","journal-title":"J Pain"},{"key":"10.1016\/j.jpain.2015.12.007_bib22","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.jpain.2008.01.328","article-title":"Muscle inflammation induces a protein kinase Cepsilon-dependent chronic-latent muscle pain","volume":"9","author":"Dina","year":"2008","journal-title":"J Pain"},{"key":"10.1016\/j.jpain.2015.12.007_bib23","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/j.pain.2011.11.020","article-title":"Targeting A-type K(+) channels in primary sensory neurons for bone cancer pain in a rat model","volume":"153","author":"Duan","year":"2012","journal-title":"Pain"},{"key":"10.1016\/j.jpain.2015.12.007_bib24","doi-asserted-by":"crossref","first-page":"3760","DOI":"10.1172\/JCI42843","article-title":"Nociceptors: The sensors of the pain pathway","volume":"120","author":"Dubin","year":"2010","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jpain.2015.12.007_bib25","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/j.neuroscience.2009.11.029","article-title":"Nociceptor subpopulations involved in hyperalgesic priming","volume":"165","author":"Ferrari","year":"2010","journal-title":"Neuroscience"},{"key":"10.1016\/j.jpain.2015.12.007_bib26","doi-asserted-by":"crossref","first-page":"4170","DOI":"10.1073\/pnas.0611704104","article-title":"Ischemic insults promote epigenetic reprogramming of mu opioid receptor expression in hippocampal neurons","volume":"104","author":"Formisano","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jpain.2015.12.007_bib27","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1054\/jhsb.2001.0633","article-title":"Vibration damage to the hand: Clinical presentation, prognosis and length and severity of vibration required","volume":"26","author":"Frid\u00e9n","year":"2001","journal-title":"J Hand Surg Br"},{"key":"10.1016\/j.jpain.2015.12.007_bib28","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1093\/occmed\/kqt167","article-title":"The effect of hand-arm vibration syndrome on quality of life","volume":"64","author":"House","year":"2014","journal-title":"Occup Med (Lond)"},{"key":"10.1016\/j.jpain.2015.12.007_bib29","doi-asserted-by":"crossref","first-page":"924","DOI":"10.1016\/S1474-4422(14)70102-4","article-title":"Allodynia and hyperalgesia in neuropathic pain: Clinical manifestations and mechanisms","volume":"13","author":"Jensen","year":"2014","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.jpain.2015.12.007_bib30","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.neuroscience.2010.04.082","article-title":"Hyperalgesic priming is restricted to isolectin B4-positive nociceptors","volume":"169","author":"Joseph","year":"2010","journal-title":"Neuroscience"},{"key":"10.1016\/j.jpain.2015.12.007_bib31","doi-asserted-by":"crossref","first-page":"363","DOI":"10.5271\/sjweh.2043","article-title":"Pathogenic and clinical aspects of polyneuropathies, with reference to the hand-arm vibration syndrome","volume":"13","author":"Juntunen","year":"1987","journal-title":"Scand J Work Environ Health"},{"key":"10.1016\/j.jpain.2015.12.007_bib32","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/S0169-328X(02)00388-1","article-title":"Downregulation of voltage-gated potassium channel alpha gene expression in dorsal root ganglia following chronic constriction injury of the rat sciatic nerve","volume":"105","author":"Kim","year":"2002","journal-title":"Brain Res Mol Brain Res"},{"key":"10.1016\/j.jpain.2015.12.007_bib33","doi-asserted-by":"crossref","first-page":"3262","DOI":"10.1002\/cne.23595","article-title":"Kv7.2 regulates the function of peripheral sensory neurons","volume":"522","author":"King","year":"2014","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.jpain.2015.12.007_bib34","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.yjmcc.2010.05.004","article-title":"High-mobility group box 1 (HMGB1) downregulates cardiac transient outward potassium current (Ito) through downregulation of Kv4.2 and Kv4.3 channel transcripts and proteins","volume":"49","author":"Liu","year":"2010","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.jpain.2015.12.007_bib35","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1002\/mus.21235","article-title":"Persistent reduction of conduction velocity and myelinated axon damage in vibrated rat tail nerves","volume":"39","author":"Loffredo","year":"2009","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.jpain.2015.12.007_bib36","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/1056-8719(94)90087-6","article-title":"A method to perform direct transcutaneous intrathecal injection in rats","volume":"32","author":"Mestre","year":"1994","journal-title":"J Pharmacol Toxicol Methods"},{"key":"10.1016\/j.jpain.2015.12.007_bib37","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.pain.2008.10.024","article-title":"Peripheral mechanisms underlying the essential role of P2X3,2\/3 receptors in the development of inflammatory hyperalgesia","volume":"141","author":"Oliveira","year":"2009","journal-title":"Pain"},{"key":"10.1016\/j.jpain.2015.12.007_bib38","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.1046\/j.1460-9568.2003.02626.x","article-title":"Tumor necrosis factor receptor type-1 in sensory neurons contributes to induction of chronic enhancement of inflammatory hyperalgesia in rat","volume":"17","author":"Parada","year":"2003","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.jpain.2015.12.007_bib39","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0306-4522(03)00267-7","article-title":"Transient attenuation of protein kinase Cepsilon can terminate a chronic hyperalgesic state in the rat","volume":"120","author":"Parada","year":"2003","journal-title":"Neuroscience"},{"key":"10.1016\/j.jpain.2015.12.007_bib40","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0304-3940(93)90787-L","article-title":"The plant lectin Bandeiraea simplicifolia I-B4 identifies a subpopulation of small diameter primary sensory neurones which innervate the skin in the rat","volume":"159","author":"Plenderleith","year":"1993","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.jpain.2015.12.007_bib41","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1080\/15298669091370013","article-title":"Vibration exposure for selected power hand tools used in automobile assembly","volume":"51","author":"Radwin","year":"1990","journal-title":"Am Ind Hyg Assoc J"},{"key":"10.1016\/j.jpain.2015.12.007_bib42","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1002\/mus.22206","article-title":"Vibration from a riveting hammer causes severe nerve damage in the rat tail model","volume":"44","author":"Raju","year":"2011","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.jpain.2015.12.007_bib43","doi-asserted-by":"crossref","first-page":"13373","DOI":"10.1073\/pnas.231376298","article-title":"Distinct potassium channels on pain-sensing neurons","volume":"98","author":"Rasband","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.jpain.2015.12.007_bib44","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.tins.2009.07.007","article-title":"Critical role of nociceptor plasticity in chronic pain","volume":"32","author":"Reichling","year":"2009","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.jpain.2015.12.007_bib45","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1523\/JNEUROSCI.1594-14.2015","article-title":"Dysregulation of Kv3.4 channels in dorsal root ganglia following spinal cord injury","volume":"35","author":"Ritter","year":"2015","journal-title":"J Neurosci"},{"key":"10.1016\/j.jpain.2015.12.007_bib46","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.pain.2009.11.022","article-title":"NGF induces non-inflammatory localized and lasting mechanical and thermal hypersensitivity in human skin","volume":"148","author":"Rukwied","year":"2010","journal-title":"Pain"},{"key":"10.1016\/j.jpain.2015.12.007_bib47","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/S0304-3959(03)00115-5","article-title":"Intramuscular injection of tumor necrosis factor-alpha induces muscle hyperalgesia in rats","volume":"104","author":"Sch\u00e4fers","year":"2003","journal-title":"Pain"},{"key":"10.1016\/j.jpain.2015.12.007_bib48","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.neuroscience.2014.11.020","article-title":"Muscle hyperalgesia induced by peripheral P2X3 receptors is modulated by inflammatory mediators","volume":"285","author":"Schiavuzzo","year":"2015","journal-title":"Neuroscience"},{"key":"10.1016\/j.jpain.2015.12.007_bib49","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1038\/nn1992","article-title":"The neuropathic pain triad: Neurons, immune cells and glia","volume":"10","author":"Scholz","year":"2007","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.jpain.2015.12.007_bib50","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.neuroscience.2004.12.036","article-title":"Mechanical and heat sensitization of cutaneous nociceptors in rats with experimental peripheral neuropathy","volume":"132","author":"Shim","year":"2005","journal-title":"Neuroscience"},{"key":"10.1016\/j.jpain.2015.12.007_bib51","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1186\/1744-8069-9-61","article-title":"Mechanical sensitization of cutaneous sensory fibers in the spared nerve injury mouse model","volume":"9","author":"Smith","year":"2013","journal-title":"Mol Pain"},{"key":"10.1016\/j.jpain.2015.12.007_bib52","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1046\/j.1529-8027.2002.02002.x","article-title":"Degeneration and regeneration of the peripheral nervous system: from Augustus Waller's observations to neuroinflammation","volume":"7","author":"Stoll","year":"2002","journal-title":"J Peripher Nerv Syst"},{"key":"10.1016\/j.jpain.2015.12.007_bib53","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.pain.2007.05.012","article-title":"Proinflammatory cytokines mediating burn-injury pain","volume":"135","author":"Summer","year":"2008","journal-title":"Pain"},{"key":"10.1016\/j.jpain.2015.12.007_bib54","doi-asserted-by":"crossref","first-page":"280","DOI":"10.5271\/sjweh.2140","article-title":"Pathological changes observed in the finger biopsy of patients with vibration-induced white finger","volume":"12","author":"Takeuchi","year":"1986","journal-title":"Scand J Work Environ Health"},{"key":"10.1016\/j.jpain.2015.12.007_bib55","doi-asserted-by":"crossref","first-page":"6480","DOI":"10.1523\/JNEUROSCI.18-16-06480.1998","article-title":"Nociceptor hyper-responsiveness during vincristine-induced painful peripheral neuropathy in the rat","volume":"18","author":"Tanner","year":"1998","journal-title":"J Neurosci"},{"key":"10.1016\/j.jpain.2015.12.007_bib56","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.neuroscience.2009.12.021","article-title":"Neuron-restrictive silencer factor causes epigenetic silencing of Kv4.3 gene after peripheral nerve injury","volume":"166","author":"Uchida","year":"2010","journal-title":"Neuroscience"},{"key":"10.1016\/j.jpain.2015.12.007_bib57","doi-asserted-by":"crossref","first-page":"3401","DOI":"10.1152\/jn.01267.2004","article-title":"A-type voltage-gated K+ currents influence firing properties of isolectin B4-positive but not isolectin B4-negative primary sensory neurons","volume":"93","author":"Vydyanathan","year":"2005","journal-title":"J Neurophysiol"}],"container-title":["The Journal of Pain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1526590015009864?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1526590015009864?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T08:48:28Z","timestamp":1718268508000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1526590015009864"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4]]},"references-count":57,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,4]]}},"alternative-id":["S1526590015009864"],"URL":"https:\/\/doi.org\/10.1016\/j.jpain.2015.12.007","relation":{},"ISSN":["1526-5900"],"issn-type":[{"value":"1526-5900","type":"print"}],"subject":[],"published":{"date-parts":[[2016,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Role of Kv4.3 in Vibration-Induced Muscle Pain in the Rat","name":"articletitle","label":"Article Title"},{"value":"The Journal of Pain","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpain.2015.12.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 American Pain Society. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}