{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:34:22Z","timestamp":1790739262031,"version":"4.1.0"},"reference-count":45,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T00:00:00Z","timestamp":1694390400000},"content-version":"vor","delay-in-days":1989,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"Cambridge Arthritis Research Endeavour"},{"name":"Cambridge University Hospitals NHS Foundation Trust"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","jpain.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pain"],"published-print":{"date-parts":[[2018,4]]},"DOI":"10.1016\/j.jpain.2017.11.008","type":"journal-article","created":{"date-parts":[[2017,12,8]],"date-time":"2017-12-08T19:17:05Z","timestamp":1512760625000},"page":"395-409","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Altered Neurocognitive Processing of Tactile Stimuli in Patients with Complex Regional Pain Syndrome"],"prefix":"10.1016","volume":"19","author":[{"given":"Anoop","family":"Kuttikat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valdas","family":"Noreika","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srivas","family":"Chennu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Shenker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tristan","family":"Bekinschtein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1414-2635","authenticated-orcid":false,"given":"Christopher A.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpain.2017.11.008_bib0010","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1038\/nrn3950","article-title":"Interoceptive predictions in the brain","volume":"16","author":"Barrett","year":"2015","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.jpain.2017.11.008_bib0015","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1162\/neco.1995.7.6.1129","article-title":"An information-maximization approach to blind separation and blind deconvolution","volume":"7","author":"Bell","year":"1995","journal-title":"Neural Comput"},{"key":"10.1016\/j.jpain.2017.11.008_bib0020","first-page":"371","article-title":"The lower extremity functional scale (LEFS): Scale development, measurement properties, and clinical application","volume":"79","author":"Binkley","year":"1999","journal-title":"Phys Ther"},{"key":"10.1016\/j.jpain.2017.11.008_bib0025","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1093\/brain\/awl004","article-title":"The precuneus: A review of its functional anatomy and behavioural correlates","volume":"129","author":"Cavanna","year":"2006","journal-title":"Brain"},{"key":"10.1016\/j.jpain.2017.11.008_bib0030","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.nicl.2013.10.008","article-title":"Dissociable endogenous and exogenous attention in disorders of consciousness","volume":"3","author":"Chennu","year":"2013","journal-title":"NeuroImage Clin"},{"key":"10.1016\/j.jpain.2017.11.008_bib0035","doi-asserted-by":"crossref","first-page":"11194","DOI":"10.1523\/JNEUROSCI.0114-13.2013","article-title":"Expectation and attention in hierarchical auditory prediction","volume":"33","author":"Chennu","year":"2013","journal-title":"J Neurosci"},{"key":"10.1016\/j.jpain.2017.11.008_bib0040","first-page":"129","article-title":"Pain assessment: Global use of the Brief Pain Inventory","volume":"23","author":"Cleeland","year":"1994","journal-title":"Ann Acad Med Singapore"},{"key":"10.1016\/j.jpain.2017.11.008_bib0045","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0926-6410(98)00009-3","article-title":"P3a, perceptual distinctiveness, and stimulus modality","volume":"7","author":"Comerchero","year":"1998","journal-title":"Brain Res Cogn Brain Res"},{"key":"10.1016\/j.jpain.2017.11.008_bib0050","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.jneumeth.2003.10.009","article-title":"EEGLAB: An open source toolbox for analysis of single-trial EEG dynamics including independent component analysis","volume":"134","author":"Delorme","year":"2004","journal-title":"J Neurosci Methods"},{"key":"10.1016\/j.jpain.2017.11.008_bib0055","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1053\/eujp.2001.0342","article-title":"The auditory event related potentials in episodic and chronic pain sufferers","volume":"6","author":"DeMirci","year":"2002","journal-title":"Eur J Pain"},{"key":"10.1016\/j.jpain.2017.11.008_bib0060","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1016\/j.jpain.2013.04.001","article-title":"Primary somatosensory cortex function in complex regional pain syndrome: A systematic review and meta-analysis","volume":"14","author":"Di Pietro","year":"2013","journal-title":"J Pain"},{"key":"10.1016\/j.jpain.2017.11.008_bib0065","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1002\/hbm.22643","article-title":"Interhemispheric somatosensory differences in chronic pain reflect abnormality of the Healthy side","volume":"36","author":"Di Pietro","year":"2015","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.jpain.2017.11.008_bib0070","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1016\/j.clinph.2009.07.045","article-title":"Event-related potentials in clinical research: Guidelines for eliciting, recording, and quantifying mismatch negativity, P300, and N400","volume":"120","author":"Duncan","year":"2009","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.jpain.2017.11.008_bib0075","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/j.pain.2004.05.019","article-title":"Impaired self-perception of the hand in complex regional pain syndrome (CRPS)","volume":"110","author":"F\u00f6rderreuther","year":"2004","journal-title":"Pain"},{"key":"10.1016\/j.jpain.2017.11.008_bib0080","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S0885-3924(99)00076-7","article-title":"Neglect-like symptoms in CRPS. Results of a self-administered survey","volume":"18","author":"Galer","year":"1999","journal-title":"J Pain Symptom Manage"},{"key":"10.1016\/j.jpain.2017.11.008_bib0085","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1111\/j.1526-4637.2006.00169.x","article-title":"Proposed new diagnostic criteria for complex regional pain syndrome","volume":"8","author":"Harden","year":"2007","journal-title":"Pain Med"},{"key":"10.1016\/j.jpain.2017.11.008_bib0090","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/S0896-6273(02)00613-X","article-title":"Temporal evolution of a decision-making process in medial premotor cortex","volume":"33","author":"Hern\u00e1ndez","year":"2002","journal-title":"Neuron"},{"key":"10.1016\/j.jpain.2017.11.008_bib0095","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1152\/jn.00533.2011","article-title":"Roles of default-mode network and supplementary motor area in human vigilance performance: Evidence from real-time fMRI","volume":"109","author":"Hinds","year":"2013","journal-title":"J Neurophysiol"},{"key":"10.1016\/j.jpain.2017.11.008_bib0100","series-title":"IBM SPSS Statistics for Windows, Version 21.0","author":"IBM","year":"2012"},{"key":"10.1016\/j.jpain.2017.11.008_bib0105","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.pain.2004.03.003","article-title":"P300-amplitudes in upper limb amputees with and without phantom limb pain in a visual oddball paradigm","volume":"110","author":"Karl","year":"2004","journal-title":"Pain"},{"key":"10.1016\/j.jpain.2017.11.008_bib0110","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.neuropsychologia.2014.09.028","article-title":"Role of the precuneus in the detection of incongruency between tactile and visual texture information: A functional MRI study","volume":"64","author":"Kitada","year":"2014","journal-title":"Neuropsychologia"},{"key":"10.1016\/j.jpain.2017.11.008_bib0115","doi-asserted-by":"crossref","first-page":"16","DOI":"10.3389\/fnhum.2016.00016","article-title":"Neurocognitive and neuroplastic mechanisms of novel clinical signs in CRPS","volume":"10","author":"Kuttikat","year":"2016","journal-title":"Front Hum Neurosci"},{"key":"10.1016\/j.jpain.2017.11.008_bib0120","article-title":"Novel signs and their clinical utility in diagnosing complex regional pain syndrome (CRPS)\u2014a prospective observational cohort study","volume":"1","author":"Kuttikat","year":"2016","journal-title":"Clin J Pain"},{"key":"10.1016\/j.jpain.2017.11.008_bib0125","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1016\/j.neuroimage.2008.06.022","article-title":"Electromagnetic source reconstruction for group studies","volume":"42","author":"Litvak","year":"2008","journal-title":"Neuroimage"},{"key":"10.1016\/j.jpain.2017.11.008_bib0130","doi-asserted-by":"crossref","first-page":"852961","DOI":"10.1155\/2011\/852961","article-title":"EEG and MEG data analysis in SPM8","volume":"2011","author":"Litvak","year":"2011","journal-title":"Comput Intell Neurosci"},{"key":"10.1016\/j.jpain.2017.11.008_bib0135","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/S1474-4422(11)70106-5","article-title":"Clinical features and pathophysiology of CRPS","volume":"10","author":"Marinus","year":"2011","journal-title":"Lancet Neurol"},{"key":"10.1016\/j.jpain.2017.11.008_bib0140","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.brainres.2006.12.067","article-title":"The effect of task-relevance on primary somatosensory cortex during continuous sensory-guided movement in the presence of bimodal competition","volume":"1138","author":"Meehan","year":"2007","journal-title":"Brain Res"},{"key":"10.1016\/j.jpain.2017.11.008_bib0145","doi-asserted-by":"crossref","first-page":"2182","DOI":"10.1212\/01.WNL.0000130156.05828.43","article-title":"Why do people with complex regional pain syndrome take longer to recognize their affected hand?","volume":"62","author":"Moseley","year":"2004","journal-title":"Neurology"},{"key":"10.1016\/j.jpain.2017.11.008_bib0150","doi-asserted-by":"crossref","first-page":"172","DOI":"10.3389\/fneur.2012.00172","article-title":"P300 and neuropsychological assessment in mild cognitive impairment and Alzheimer dementia","volume":"3","author":"Parra","year":"2012","journal-title":"Front Neurol"},{"key":"10.1016\/j.jpain.2017.11.008_bib0155","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.neuroimage.2006.03.045","article-title":"Patterns of cortical reorganization parallel impaired tactile discrimination and pain intensity in complex regional pain syndrome","volume":"32","author":"Pleger","year":"2006","journal-title":"Neuroimage"},{"key":"10.1016\/j.jpain.2017.11.008_bib0160","doi-asserted-by":"crossref","first-page":"2128","DOI":"10.1016\/j.clinph.2007.04.019","article-title":"Updating P300: An integrative theory of P3a and P3b","volume":"118","author":"Polich","year":"2009","journal-title":"Clin Neurophysiol"},{"key":"10.1016\/j.jpain.2017.11.008_bib0165","doi-asserted-by":"crossref","first-page":"13231","DOI":"10.1523\/JNEUROSCI.2767-06.2006","article-title":"Neural correlates of vibrotactile working memory in the human brain","volume":"26","author":"Preuschhof","year":"2006","journal-title":"J Neurosci"},{"key":"10.1016\/j.jpain.2017.11.008_bib0170","doi-asserted-by":"crossref","first-page":"557","DOI":"10.3389\/fnhum.2014.00557","article-title":"Intraindividual reaction time variability affects P300 amplitude rather than latency","volume":"8","author":"Ramchurn","year":"2014","journal-title":"Front Hum Neurosci"},{"key":"10.1016\/j.jpain.2017.11.008_bib0175","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/nrn1058","article-title":"Flutter discrimination: Neural codes, perception, memory and decision making","volume":"4","author":"Romo","year":"2003","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.jpain.2017.11.008_bib0180","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.1600-0447.1983.tb09716.x","article-title":"The hospital anxiety and depression scale","volume":"67","author":"Zigmond","year":"1983","journal-title":"Acta Psychiatr Scand"},{"key":"10.1016\/j.jpain.2017.11.008_bib0185","first-page":"259","article-title":"Development and initial validation of the upper extremity functional index","volume":"53","author":"Stratford","year":"2001","journal-title":"Physiother Can"},{"key":"10.1016\/j.jpain.2017.11.008_bib0190","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1111\/j.1365-2044.1997.228-az0363.x","article-title":"Event-related evoked potential responses (P 300) following epidural methylprednisolone therapy in chronic low back pain patients","volume":"52","author":"Tandon","year":"1997","journal-title":"Anaesthesia"},{"key":"10.1016\/j.jpain.2017.11.008_bib0195","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/0306-4522(96)00287-4","article-title":"Generators for human P300 elicited by somatosensory stimuli using multiple dipole source analysis","volume":"75","author":"Tarkka","year":"1996","journal-title":"Neuroscience"},{"key":"10.1016\/j.jpain.2017.11.008_bib0200","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1007\/s11062-015-9510-5","article-title":"Auditory event-related p300 potentials in rheumatoid arthritis patients","volume":"47","author":"Tomasevic-Todorovic","year":"2015","journal-title":"Neurophysiology"},{"key":"10.1016\/j.jpain.2017.11.008_bib0205","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1093\/schbul\/sbl060","article-title":"Neurophysiological endophenotypes of schizophrenia: The viability of selected candidate measures","volume":"33","author":"Turetsky","year":"2006","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.jpain.2017.11.008_bib0210","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1002\/ejp.882","article-title":"Is the brain of complex regional pain syndrome patients truly different?","volume":"20","author":"van Velzen","year":"2016","journal-title":"Eur J Pain"},{"key":"10.1016\/j.jpain.2017.11.008_bib0215","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1002\/mus.1203","article-title":"Dipolar source modeling of the P300 event-related potential after somatosensory stimulation","volume":"24","author":"Valeriani","year":"2001","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.jpain.2017.11.008_bib9005","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1214\/10-AOAS337","article-title":"Topological inference for EEG and MEG","volume":"4","author":"Kilner","year":"2010","journal-title":"Ann Appl Stat"},{"key":"10.1016\/j.jpain.2017.11.008_bib9010","series-title":"Statistical parametric mapping: The analysis of functional brain images","first-page":"352","article-title":"Forward models for EEG","author":"Phillips","year":"2007"},{"key":"10.1016\/j.jpain.2017.11.008_bib9015","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/j.neuroimage.2005.10.037","article-title":"MEG source localization under multiple constraints: An extended Bayesian framework","volume":"30","author":"Mattout","year":"2006","journal-title":"Neuroimage"}],"container-title":["The Journal of Pain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S152659001730785X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S152659001730785X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,9,16]],"date-time":"2023-09-16T19:58:32Z","timestamp":1694894312000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S152659001730785X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4]]},"references-count":45,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,4]]}},"alternative-id":["S152659001730785X"],"URL":"https:\/\/doi.org\/10.1016\/j.jpain.2017.11.008","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/146613","asserted-by":"object"}]},"ISSN":["1526-5900"],"issn-type":[{"value":"1526-5900","type":"print"}],"subject":[],"published":{"date-parts":[[2018,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Altered Neurocognitive Processing of Tactile Stimuli in Patients with Complex Regional Pain Syndrome","name":"articletitle","label":"Article Title"},{"value":"The Journal of Pain","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpain.2017.11.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 by the American Pain Society","name":"copyright","label":"Copyright"}]}}