{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T19:20:53Z","timestamp":1790882453835,"version":"4.1.0"},"reference-count":47,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["111-2314-B-075 -013"],"award-info":[{"award-number":["111-2314-B-075 -013"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["MOST111-2314-B-075 -014 -MY2"],"award-info":[{"award-number":["MOST111-2314-B-075 -014 -MY2"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["109-2314-B-010-050-MY3"],"award-info":[{"award-number":["109-2314-B-010-050-MY3"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["NSTC113-2314-B-075-042"],"award-info":[{"award-number":["NSTC113-2314-B-075-042"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["MOST110-2314-B-075-024 -MY3"],"award-info":[{"award-number":["MOST110-2314-B-075-024 -MY3"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["MOST110-2314-B-075-026"],"award-info":[{"award-number":["MOST110-2314-B-075-026"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011912","name":"Taipei Veterans General Hospital","doi-asserted-by":"publisher","award":["V113C-011"],"award-info":[{"award-number":["V113C-011"]}],"id":[{"id":"10.13039\/501100011912","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011912","name":"Taipei Veterans General Hospital","doi-asserted-by":"publisher","award":["V114C-064"],"award-info":[{"award-number":["V114C-064"]}],"id":[{"id":"10.13039\/501100011912","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011912","name":"Taipei Veterans General Hospital","doi-asserted-by":"publisher","award":["V113C-039"],"award-info":[{"award-number":["V113C-039"]}],"id":[{"id":"10.13039\/501100011912","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011912","name":"Taipei Veterans General Hospital","doi-asserted-by":"publisher","award":["V113C-010"],"award-info":[{"award-number":["V113C-010"]}],"id":[{"id":"10.13039\/501100011912","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011912","name":"Taipei Veterans General Hospital","doi-asserted-by":"publisher","award":["V114C-089"],"award-info":[{"award-number":["V114C-089"]}],"id":[{"id":"10.13039\/501100011912","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011912","name":"Taipei Veterans General Hospital","doi-asserted-by":"publisher","award":["V114C-217"],"award-info":[{"award-number":["V114C-217"]}],"id":[{"id":"10.13039\/501100011912","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011913","name":"Kaohsiung Veterans General Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011913","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010425","name":"Tri-Service General Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010425","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007354","name":"Yen Tjing Ling Medical Foundation","doi-asserted-by":"publisher","award":["CI-113-32"],"award-info":[{"award-number":["CI-113-32"]}],"id":[{"id":"10.13039\/501100007354","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007354","name":"Yen Tjing Ling Medical Foundation","doi-asserted-by":"publisher","award":["CI-114-35"],"award-info":[{"award-number":["CI-114-35"]}],"id":[{"id":"10.13039\/501100007354","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007354","name":"Yen Tjing Ling Medical Foundation","doi-asserted-by":"publisher","award":["CI-113-30"],"award-info":[{"award-number":["CI-113-30"]}],"id":[{"id":"10.13039\/501100007354","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001869","name":"Academia Sinica","doi-asserted-by":"publisher","award":["VTA114-V1-4-1"],"award-info":[{"award-number":["VTA114-V1-4-1"]}],"id":[{"id":"10.13039\/501100001869","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001869","name":"Academia Sinica","doi-asserted-by":"publisher","award":["VTA112-V1-6-1"],"award-info":[{"award-number":["VTA112-V1-6-1"]}],"id":[{"id":"10.13039\/501100001869","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jpain.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pain"],"published-print":{"date-parts":[[2025,4]]},"DOI":"10.1016\/j.jpain.2025.105335","type":"journal-article","created":{"date-parts":[[2025,2,8]],"date-time":"2025-02-08T11:29:29Z","timestamp":1739014169000},"page":"105335","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Risks and familial coaggregation of suicide, accident mortality, and psychiatric disorders in first-degree relatives of individuals with migraine"],"prefix":"10.1016","volume":"29","author":[{"given":"Ju-Wei","family":"Hsu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shih-Jen","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Han","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih-Ming","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3779-9074","authenticated-orcid":false,"given":"Ya-Mei","family":"Bai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tung-Ping","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tzeng-Ji","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6516-1073","authenticated-orcid":false,"given":"Mu-Hong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.jpain.2025.105335_bib1","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1017\/thg.2016.43","article-title":"Familial aggregation of migraine and depression: insights from a large Australian twin sample","volume":"19","author":"Yang","year":"2016","journal-title":"Twin Research and Human Genetics"},{"issue":"3","key":"10.1016\/j.jpain.2025.105335_bib2","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2019.0154","article-title":"Family history of mental and neurological disorders and risk of autism","volume":"2","author":"Xie","year":"2019","journal-title":"JAMA Network Open"},{"key":"10.1016\/j.jpain.2025.105335_bib3","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.jad.2016.07.034","article-title":"Parental and comorbid migraine in individuals with bipolar disorder: A nationwide register study","volume":"206","author":"Sucksdorff","year":"2016","journal-title":"Journal of Affective Disorders"},{"issue":"6395","key":"10.1016\/j.jpain.2025.105335_bib4","article-title":"Analysis of shared heritability in common disorders of the brain","volume":"360","author":"Brainstorm","year":"2018","journal-title":"Science"},{"issue":"1","key":"10.1016\/j.jpain.2025.105335_bib5","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1093\/brain\/awab267","article-title":"Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools","volume":"145","author":"Bahrami","year":"2022","journal-title":"Brain"},{"issue":"3","key":"10.1016\/j.jpain.2025.105335_bib6","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1111\/head.12300","article-title":"Influence of family psychiatric and headache history on migraine-related health care utilization","volume":"54","author":"Minen","year":"2014","journal-title":"Headache"},{"issue":"6","key":"10.1016\/j.jpain.2025.105335_bib7","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1016\/j.biopsych.2007.07.021","article-title":"Panic disorder, social anxiety disorder, and a possible medical syndrome previously linked to chromosome 13","volume":"63","author":"Talati","year":"2008","journal-title":"Biological Psychiatry"},{"issue":"1","key":"10.1016\/j.jpain.2025.105335_bib8","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.1526-4610.2006.00629.x","article-title":"Similarities and differences between chronic migraine and episodic migraine","volume":"47","author":"Ferrari","year":"2007","journal-title":"Headache"},{"issue":"1","key":"10.1016\/j.jpain.2025.105335_bib9","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1111\/j.1468-2982.2008.01698.x","article-title":"Parental psychopathology and migraine headaches among adolescent girls","volume":"29","author":"Marmorstein","year":"2009","journal-title":"Cephalalgia"},{"key":"10.1016\/j.jpain.2025.105335_bib10","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2023.1160204","article-title":"Risks of suicide in migraine, non-migraine headache, back, and neck pain: a systematic review and meta-analysis","volume":"14","author":"Giakas","year":"2023","journal-title":"Frontiers in Neurology"},{"issue":"1","key":"10.1016\/j.jpain.2025.105335_bib11","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1111\/head.13716","article-title":"The influence of migraine on driving: current understanding, future directions, and potential implications of findings","volume":"60","author":"Tepper","year":"2020","journal-title":"Headache"},{"key":"10.1016\/j.jpain.2025.105335_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.mayocp.2024.06.014","article-title":"Familial coaggregation of suicide, accidental death, and major psychiatric disorders in first-degree relatives of individuals dying accidentally","author":"Chen","year":"2024","journal-title":"Mayo Clinic Proceedings"},{"issue":"4","key":"10.1016\/j.jpain.2025.105335_bib13","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1192\/bjp.2023.85","article-title":"Risks and familial coaggregation of death by suicide, accidental death and major psychiatric disorders in first-degree relatives of individuals who died by suicide","volume":"223","author":"Tsai","year":"2023","journal-title":"The British Journal of Psychiatry: The Journal of Mental Science"},{"issue":"2","key":"10.1016\/j.jpain.2025.105335_bib14","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1017\/S0033291706008750","article-title":"The endophenotype concept in psychiatric genetics","volume":"37","author":"Flint","year":"2007","journal-title":"Psychological Medicine"},{"issue":"1","key":"10.1016\/j.jpain.2025.105335_bib15","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1038\/s41398-020-00872-9","article-title":"Shared polygenic risk for ADHD, executive dysfunction and other psychiatric disorders","volume":"10","author":"Chang","year":"2020","journal-title":"Translational Psychiatry"},{"issue":"1","key":"10.1016\/j.jpain.2025.105335_bib16","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1186\/s10194-020-01187-2","article-title":"Response inhibition alterations in migraine: evidence from event-related potentials and evoked oscillations","volume":"21","author":"Chen","year":"2020","journal-title":"The Journal of Headache and Pain"},{"issue":"8","key":"10.1016\/j.jpain.2025.105335_bib17","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1038\/mp.2017.217","article-title":"Co-aggregation of major psychiatric disorders in individuals with first-degree relatives with schizophrenia: a nationwide population-based study","volume":"23","author":"Cheng","year":"2018","journal-title":"Molecular Psychiatry"},{"issue":"14","key":"10.1016\/j.jpain.2025.105335_bib18","doi-asserted-by":"crossref","first-page":"2397","DOI":"10.1017\/S003329171800332X","article-title":"Risk and coaggregation of major psychiatric disorders among first-degree relatives of patients with bipolar disorder: a nationwide population-based study","volume":"49","author":"Chen","year":"2019","journal-title":"Psychological Medicine"},{"key":"10.1016\/j.jpain.2025.105335_bib19","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.jpsychires.2023.07.022","article-title":"Effects of low-dose ketamine infusion on vascular endothelial growth factor and matrix metalloproteinase-9 among patients with treatment-resistant depression and suicidal ideation","volume":"165","author":"Chen","year":"2023","journal-title":"Journal of Psychiatric Research"},{"issue":"5","key":"10.1016\/j.jpain.2025.105335_bib20","doi-asserted-by":"crossref","first-page":"788","DOI":"10.2337\/dc15-1807","article-title":"Risk of developing type 2 diabetes in adolescents and young adults with autism spectrum disorder: a nationwide longitudinal study","volume":"39","author":"Chen","year":"2016","journal-title":"Diabetes Care"},{"key":"10.1016\/j.jpain.2025.105335_bib21","first-page":"1","article-title":"Familial coaggregation of major psychiatric disorders among first-degree relatives of patients with obsessive-compulsive disorder: a nationwide study","author":"Huang","year":"2020","journal-title":"Psychological Medicine"},{"issue":"5","key":"10.1016\/j.jpain.2025.105335_bib22","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/0021-9681(87)90171-8","article-title":"A new method of classifying prognostic comorbidity in longitudinal studies: development and validation","volume":"40","author":"Charlson","year":"1987","journal-title":"Journal of Chronic Diseases"},{"key":"10.1016\/j.jpain.2025.105335_bib23","first-page":"1","article-title":"Incorporating development stratification of Taiwan townships into sampling design of large scale health interview survey","volume":"4","author":"Liu","year":"2006","journal-title":"Journal\u00a0of\u00a0Health Management (Chin)"},{"issue":"7","key":"10.1016\/j.jpain.2025.105335_bib24","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1093\/aje\/kwh090","article-title":"A modified poisson regression approach to prospective studies with binary data","volume":"159","author":"Zou","year":"2004","journal-title":"American Journal of Epidemiology"},{"issue":"2","key":"10.1016\/j.jpain.2025.105335_bib25","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1001\/archpsyc.60.2.170","article-title":"Family study of affective spectrum disorder","volume":"60","author":"Hudson","year":"2003","journal-title":"Archives Of General Psychiatry"},{"issue":"5","key":"10.1016\/j.jpain.2025.105335_bib26","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1176\/ajp.147.5.552","article-title":"Hudson JI, Pope HG, Jr. Affective spectrum disorder: does antidepressant response identify a family of disorders with a common pathophysiology?","volume":"147","year":"1990","journal-title":"American Journal of\u00a0Psychiatry"},{"issue":"11","key":"10.1016\/j.jpain.2025.105335_bib27","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/s11920-018-0969-9","article-title":"Social determinants of mental health: where we are and where we need to go","volume":"20","author":"Alegria","year":"2018","journal-title":"Current Psychiatry Reports"},{"issue":"1","key":"10.1016\/j.jpain.2025.105335_bib28","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1097\/YPG.0b013e32834acd07","article-title":"Genome-wide association study of comorbid depressive syndrome and alcohol dependence","volume":"22","author":"Edwards","year":"2012","journal-title":"Genetics in Psychiatry"},{"key":"10.1016\/j.jpain.2025.105335_bib29","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.eurpsy.2016.03.004","article-title":"Genome-wide significant loci for addiction and anxiety","volume":"36","author":"Hodgson","year":"2016","journal-title":"European Psychiatry"},{"issue":"2","key":"10.1016\/j.jpain.2025.105335_bib30","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1375\/twin.15.2.158","article-title":"Causes of comorbidity: pleiotropy or causality? Shared genetic and environmental influences on migraine and neuroticism","volume":"15","author":"Ligthart","year":"2012","journal-title":"Twin Research and Human Genetics"},{"issue":"4","key":"10.1016\/j.jpain.2025.105335_bib31","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1007\/s00702-017-1834-4","article-title":"Gamma-aminobutyric acid (GABA) receptors GABRA4, GABRE, and GABRQ gene polymorphisms and risk for migraine","volume":"125","author":"Garcia-Martin","year":"2018","journal-title":"Journal of Neural Transmission (Vienna)"},{"key":"10.1016\/j.jpain.2025.105335_bib32","doi-asserted-by":"crossref","first-page":"10","DOI":"10.3389\/fncel.2018.00010","article-title":"Missense gamma-aminobutyric acid receptor polymorphisms are associated with reaction time, motor time, and ethanol effects in vivo","volume":"12","author":"Garcia-Martin","year":"2018","journal-title":"Frontiers in Cellular Neuroscience"},{"issue":"4","key":"10.1016\/j.jpain.2025.105335_bib33","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1002\/ajmg.b.32037","article-title":"Autosomal linkage scan for loci predisposing to comorbid dependence on multiple substances","volume":"159B","author":"Yang","year":"2012","journal-title":"American Journal of Medical Genetics Part B\u00a0Neuropsychiatr Genetics"},{"issue":"2-3","key":"10.1016\/j.jpain.2025.105335_bib34","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.jad.2003.11.007","article-title":"Is migraine in unipolar depressed patients a bipolar spectrum trait?","volume":"84","author":"Oedegaard","year":"2005","journal-title":"Journal of Affective Disorders"},{"key":"10.1016\/j.jpain.2025.105335_bib35","doi-asserted-by":"crossref","DOI":"10.1017\/S2045796021000421","article-title":"Maternal migraine and the risk of psychiatric disorders in offspring: a population-based cohort study","volume":"30","author":"Wang","year":"2021","journal-title":"Epidemiology and Psychiatric Sciences"},{"key":"10.1016\/j.jpain.2025.105335_bib36","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/j.1749-6632.2008.03572.x","article-title":"Genetic calcium signaling abnormalities in the central nervous system: seizures, migraine, and autism","volume":"1151","author":"Gargus","year":"2009","journal-title":"Annals of the New York Academy of Sciences"},{"issue":"1","key":"10.1016\/j.jpain.2025.105335_bib37","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.ijdevneu.2005.10.003","article-title":"Selected neurotrophins, neuropeptides, and cytokines: developmental trajectory and concentrations in neonatal blood of children with autism or Down syndrome","volume":"24","author":"Nelson","year":"2006","journal-title":"International Journal of Developmental Neuroscience"},{"issue":"6","key":"10.1016\/j.jpain.2025.105335_bib38","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1038\/s41582-018-0003-1","article-title":"CGRP as the target of new migraine therapies - successful translation from bench to clinic","volume":"14","author":"Edvinsson","year":"2018","journal-title":"Nature Reviews Neurology"},{"key":"10.1016\/j.jpain.2025.105335_bib39","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.brainres.2007.10.063","article-title":"Further studies in the developmental hyperserotonemia model (DHS) of autism: social, behavioral and peptide changes","volume":"1189","author":"McNamara","year":"2008","journal-title":"Brain Research"},{"key":"10.1016\/j.jpain.2025.105335_bib40","first-page":"16","article-title":"JL. Comorbidities of migraine","volume":"1","author":"Chen","year":"2010","journal-title":"Frontiers in Neurology"},{"key":"10.1016\/j.jpain.2025.105335_bib41","doi-asserted-by":"crossref","DOI":"10.3389\/fpubh.2023.1140682","article-title":"Associations of migraines with suicide ideation or attempts: A meta-analysis","volume":"11","author":"Wei","year":"2023","journal-title":"Frontiers in Public Health"},{"issue":"2","key":"10.1016\/j.jpain.2025.105335_bib42","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1002\/ajmg.b.32767","article-title":"Targeted sequencing of the LRRTM gene family in suicide attempters with bipolar disorder","volume":"183","author":"Reichman","year":"2020","journal-title":"American Journal of Medical Genetics Part B Neuropsychiatr Genetics"},{"key":"10.1016\/j.jpain.2025.105335_bib43","doi-asserted-by":"crossref","DOI":"10.3389\/fnbeh.2021.749180","article-title":"A multiscale view of the mechanisms underlying ketamine's antidepressant effects: an update on neuronal calcium signaling","volume":"15","author":"Kawatake-Kuno","year":"2021","journal-title":"Frontiers in Behavioral Neuroscience"},{"issue":"1","key":"10.1016\/j.jpain.2025.105335_bib44","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1358\/dot.2020.56.1.3069863","article-title":"Galcanezumab: a humanized monoclonal antibody for the prevention of migraine and cluster headache","volume":"56","author":"Ossipov","year":"2020","journal-title":"Drugs Today ((Barc))"},{"issue":"3","key":"10.1016\/j.jpain.2025.105335_bib45","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.berh.2007.02.011","article-title":"Genetics of chronic pain states","volume":"21","author":"Buskila","year":"2007","journal-title":"Best Practice & Research: Clinical Rheumatology"},{"issue":"8","key":"10.1016\/j.jpain.2025.105335_bib46","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1111\/j.1601-0825.2008.01458.x","article-title":"Genetic contributions to pain: a review of findings in humans","volume":"14","author":"Fillingim","year":"2008","journal-title":"Oral Diseases"},{"key":"10.1016\/j.jpain.2025.105335_bib47","article-title":"Bidirectional two-sample Mendelian randomization analysis identifies causal associations between migraine and five psychiatric disorders","volume":"15","author":"Li","year":"2024","journal-title":"Frontiers in Neurology"}],"container-title":["The Journal of Pain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1526590025005620?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1526590025005620?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T11:14:12Z","timestamp":1775042052000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1526590025005620"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":47,"alternative-id":["S1526590025005620"],"URL":"https:\/\/doi.org\/10.1016\/j.jpain.2025.105335","relation":{},"ISSN":["1526-5900"],"issn-type":[{"value":"1526-5900","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Risks and familial coaggregation of suicide, accident mortality, and psychiatric disorders in first-degree relatives of individuals with migraine","name":"articletitle","label":"Article Title"},{"value":"The Journal of Pain","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpain.2025.105335","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 Published by Elsevier Inc. on behalf of United States Association for the Study of Pain, Inc","name":"copyright","label":"Copyright"}],"article-number":"105335"}}