{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T11:12:12Z","timestamp":1777893132371,"version":"3.51.4"},"reference-count":102,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2027,2,20]],"date-time":"2027-02-20T00:00:00Z","timestamp":1803081600000},"content-version":"am","delay-in-days":325,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000738","name":"US Department of Veterans Affairs","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000738","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jpain.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pain"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.jpain.2026.106212","type":"journal-article","created":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T00:47:36Z","timestamp":1770943656000},"page":"106212","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Brain mechanisms of pain anticipation in chronic low back pain: Insights into phenotypical responses to mind-body therapy"],"prefix":"10.1016","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8799-716X","authenticated-orcid":false,"given":"Irina A.","family":"Strigo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salvatore","family":"Torrisi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio Garcia","family":"Guerra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0171-3411","authenticated-orcid":false,"given":"Benedict J.","family":"Alter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey C.","family":"Lotz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0932-9844","authenticated-orcid":false,"given":"Wolf E.","family":"Mehling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan N.","family":"Simmons","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.jpain.2026.106212_bib1","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1001\/jama.2013.13805","article-title":"The state of US health, 1990-2010: burden of diseases, injuries, and risk factors","volume":"310","author":"Murray","year":"2013","journal-title":"JAMA"},{"issue":"7","key":"10.1016\/j.jpain.2026.106212_bib2","doi-asserted-by":"crossref","first-page":"514","DOI":"10.7326\/M16-2367","article-title":"Physicians* CGCotACo. Noninvasive treatments for acute, subacute, and chronic low back pain: a clinical practice guideline from the American College of Physicians","volume":"166","author":"Qaseem","year":"2017","journal-title":"Ann Intern Med"},{"issue":"2","key":"10.1016\/j.jpain.2026.106212_bib3","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1002\/ejp.931","article-title":"Clinical practice guidelines for the noninvasive management of low back pain: a systematic review by the Ontario Protocol for Traffic Injury Management (OPTIMa) collaboration","volume":"21","author":"Wong","year":"2017","journal-title":"Eur J Pain"},{"issue":"7-8","key":"10.1016\/j.jpain.2026.106212_bib4","doi-asserted-by":"crossref","first-page":"469","DOI":"10.20452\/pamw.741","article-title":"Clinical guidelines from the American Pain Society and the American Academy of Pain Medicine on the use of chronic opioid therapy in chronic noncancer pain: what are the key messages for clinical practice?","volume":"119","author":"Chou","year":"2009","journal-title":"Pol Arch Med Wewn"},{"key":"10.1016\/j.jpain.2026.106212_bib5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1472-6882-12-162","article-title":"Mindfulness-based stress reduction for low back pain. A systematic review","volume":"12","author":"Cramer","year":"2012","journal-title":"BMC Complement Altern Med"},{"issue":"2","key":"10.1016\/j.jpain.2026.106212_bib6","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/s12160-016-9844-2","article-title":"Mindfulness meditation for chronic pain: systematic review and meta-analysis","volume":"51","author":"Hilton","year":"2017","journal-title":"Ann Behav Med"},{"issue":"9","key":"10.1016\/j.jpain.2026.106212_bib7","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1016\/j.neunet.2003.06.005","article-title":"Learning and inference in the brain","volume":"16","author":"Friston","year":"2003","journal-title":"Neural Netw"},{"issue":"6","key":"10.1016\/j.jpain.2026.106212_bib8","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1016\/j.neuron.2014.02.042","article-title":"Placebo analgesia: a predictive coding perspective","volume":"81","author":"Buchel","year":"2014","journal-title":"Neuron"},{"key":"10.1016\/j.jpain.2026.106212_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.neubiorev.2024.105750","article-title":"Expectation of pain and relief: a dynamical model of the neural basis for pain-trauma co-morbidity","volume":"163","author":"Strigo","year":"2024","journal-title":"Neurosci Biobehav Rev"},{"issue":"36","key":"10.1016\/j.jpain.2026.106212_bib10","doi-asserted-by":"crossref","first-page":"12950","DOI":"10.1073\/pnas.0408576102","article-title":"The subjective experience of pain: where expectations become reality","volume":"102","author":"Koyama","year":"2005","journal-title":"Proc Natl Acad Sci USA"},{"issue":"1","key":"10.1016\/j.jpain.2026.106212_bib11","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1097\/j.pain.0000000000001272","article-title":"How expectations influence pain","volume":"159","author":"Fields","year":"2018","journal-title":"Pain"},{"issue":"2","key":"10.1016\/j.jpain.2026.106212_bib12","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1523\/JNEUROSCI.1082-19.2019","article-title":"Mesocorticolimbic pathways encode cue-based expectancy effects on pain","volume":"40","author":"Tu","year":"2020","journal-title":"J Neurosci"},{"issue":"7","key":"10.1016\/j.jpain.2026.106212_bib13","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.1523\/JNEUROSCI.2104-19.2019","article-title":"Threat prediction from schemas as a source of bias in pain perception","volume":"40","author":"Lim","year":"2020","journal-title":"J Neurosci"},{"issue":"6","key":"10.1016\/j.jpain.2026.106212_bib14","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.ejpain.2004.02.003","article-title":"Modification of attentional biases in chronic pain patients: a preliminary study","volume":"8","author":"Dehghani","year":"2004","journal-title":"Eur J Pain"},{"issue":"9","key":"10.1016\/j.jpain.2026.106212_bib15","doi-asserted-by":"crossref","first-page":"e150","DOI":"10.1097\/j.pain.0000000000003612","article-title":"Interpretation bias and its relationship with pain: a systematic review and meta-analysis","volume":"166","author":"Todd","year":"2025","journal-title":"Pain"},{"issue":"2","key":"10.1016\/j.jpain.2026.106212_bib16","article-title":"A systematic review with subset meta-analysis of studies exploring memory recall biases for pain-related information in adults with chronic pain","volume":"5","author":"Schoth","year":"2020","journal-title":"Pain Rep"},{"issue":"8","key":"10.1016\/j.jpain.2026.106212_bib17","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1097\/j.pain.0000000000003207","article-title":"Identification of group differences in predictive anticipatory biasing of pain during uncertainty: preparing for the worst but hoping for the best","volume":"165","author":"Strigo","year":"2024","journal-title":"Pain"},{"issue":"6","key":"10.1016\/j.jpain.2026.106212_bib18","doi-asserted-by":"crossref","first-page":"e316","DOI":"10.1016\/S2665-9913(23)00098-X","article-title":"Global, regional, and national burden of low back pain, 1990-2020, its attributable risk factors, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021","volume":"5","author":"2021","year":"2023","journal-title":"Lancet Rheuma"},{"issue":"10","key":"10.1016\/j.jpain.2026.106212_bib19","doi-asserted-by":"crossref","first-page":"1304","DOI":"10.1038\/nn.3811","article-title":"Reward and motivation in pain and pain relief","volume":"17","author":"Navratilova","year":"2014","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.jpain.2026.106212_bib20","series-title":"How do you feel?: an interoceptive moment with your neurobiological self","author":"Craig","year":"2015"},{"issue":"1","key":"10.1016\/j.jpain.2026.106212_bib21","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/nrn2555","article-title":"How do you feel - now? The anterior insula and human awareness","volume":"10","author":"Craig","year":"2009","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.jpain.2026.106212_bib22","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.24770","article-title":"Functional dissociation of stimulus intensity encoding and predictive coding of pain in the insula","volume":"6","author":"Geuter","year":"2017","journal-title":"Elife"},{"issue":"1","key":"10.1016\/j.jpain.2026.106212_bib23","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.neuroimage.2005.03.041","article-title":"Somatotopic organisation of the human insula to painful heat studied with high resolution functional imaging","volume":"27","author":"Brooks","year":"2005","journal-title":"Neuroimage"},{"issue":"12","key":"10.1016\/j.jpain.2026.106212_bib24","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/j.tics.2005.10.005","article-title":"Forebrain emotional asymmetry: a neuroanatomical basis?","volume":"9","author":"Craig","year":"2005","journal-title":"Trends Cogn Sci"},{"key":"10.1016\/j.jpain.2026.106212_bib25","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.neuroimage.2013.04.014","article-title":"Lateralization of affective processing in the insula","volume":"78","author":"Duerden","year":"2013","journal-title":"Neuroimage"},{"key":"10.1016\/j.jpain.2026.106212_bib26","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.neuroimage.2015.06.060","article-title":"Neural underpinnings of nocebo hyperalgesia in visceral pain: A fMRI study in healthy volunteers","volume":"120","author":"Schmid","year":"2015","journal-title":"Neuroimage"},{"issue":"11","key":"10.1016\/j.jpain.2026.106212_bib27","doi-asserted-by":"crossref","first-page":"2372","DOI":"10.1016\/j.pain.2013.07.013","article-title":"Neural mechanisms mediating positive and negative treatment expectations in visceral pain: a functional magnetic resonance imaging study on placebo and nocebo effects in healthy volunteers","volume":"154","author":"Schmid","year":"2013","journal-title":"Pain"},{"key":"10.1016\/j.jpain.2026.106212_bib28","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.neuroimage.2015.03.015","article-title":"Distinct neural representations of placebo and nocebo effects","volume":"112","author":"Freeman","year":"2015","journal-title":"Neuroimage"},{"issue":"4","key":"10.1016\/j.jpain.2026.106212_bib29","doi-asserted-by":"crossref","DOI":"10.1093\/braincomms\/fcab260","article-title":"Association of painful human immunodeficiency virus distal sensory polyneuropathy with aberrant expectation of pain relief: functional magnetic resonance imaging evidence","volume":"3","author":"Strigo","year":"2021","journal-title":"Brain Commun"},{"issue":"10","key":"10.1016\/j.jpain.2026.106212_bib30","doi-asserted-by":"crossref","first-page":"3898","DOI":"10.1002\/hbm.24219","article-title":"Altered brain activation and connectivity during anticipation of uncertain threat in trait anxiety","volume":"39","author":"Geng","year":"2018","journal-title":"Hum Brain Mapp"},{"issue":"10","key":"10.1016\/j.jpain.2026.106212_bib31","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0307690","article-title":"Mind your pain: A single-arm feasibility study to assess a smartphone-based interoceptive attention training for patients with chronic low back pain","volume":"19","author":"Mehling","year":"2024","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.jpain.2026.106212_bib32","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.2522\/ptj.2015.95.2.e1","article-title":"Report of the NIH Task Force on research standards for chronic low back pain","volume":"95","author":"Deyo","year":"2015","journal-title":"Phys Ther"},{"issue":"2","key":"10.1016\/j.jpain.2026.106212_bib33","first-page":"129","article-title":"Pain assessment: global use of the Brief Pain Inventory","volume":"23","author":"Cleeland","year":"1994","journal-title":"Ann Acad Med Singap"},{"issue":"12","key":"10.1016\/j.jpain.2026.106212_bib34","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0208034","article-title":"The Multidimensional Assessment of Interoceptive Awareness, Version 2 (MAIA-2)","volume":"13","author":"Mehling","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.jpain.2026.106212_bib35","doi-asserted-by":"crossref","first-page":"403","DOI":"10.2147\/JPR.S42418","article-title":"Self-reported interoceptive awareness in primary care patients with past or current low back pain","volume":"6","author":"Mehling","year":"2013","journal-title":"J Pain Res"},{"issue":"2","key":"10.1016\/j.jpain.2026.106212_bib36","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.jbi.2008.08.010","article-title":"Research electronic data capture (REDCap)\u2014a metadata-driven methodology and workflow process for providing translational research informatics support","volume":"42","author":"Harris","year":"2009","journal-title":"J Biomed Inform"},{"issue":"6","key":"10.1016\/j.jpain.2026.106212_bib37","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1007\/s11606-009-0981-1","article-title":"Development and initial validation of the PEG, a three-item scale assessing pain intensity and interference","volume":"24","author":"Krebs","year":"2009","journal-title":"J Gen Intern Med"},{"key":"10.1016\/j.jpain.2026.106212_bib38","first-page":"143","article-title":"The brief pain inventory","author":"Cleeland","year":"1991","journal-title":"Pain Res Group"},{"key":"10.1016\/j.jpain.2026.106212_bib39","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1037\/1040-3590.7.4.524","article-title":"The Pain Catastrophizing Scale: Develompent and Validation","volume":"7","author":"Sullivan","year":"1995","journal-title":"Psychol Assess"},{"issue":"1","key":"10.1016\/j.jpain.2026.106212_bib40","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1155\/2002\/517163","article-title":"A short version of the Pain Anxiety Symptoms Scale (PASS-20): preliminary development and validity","volume":"7","author":"McCracken","year":"2002","journal-title":"Pain Res Manag"},{"key":"10.1016\/j.jpain.2026.106212_bib41","doi-asserted-by":"crossref","first-page":"385","DOI":"10.2307\/2136404","article-title":"A global measure of perceived stress","author":"Cohen","year":"1983","journal-title":"J Health Soc Behav"},{"issue":"2","key":"10.1016\/j.jpain.2026.106212_bib42","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/0304-3959(93)90127-B","article-title":"A Fear-Avoidance Beliefs Questionnaire (FABQ) and the role of fear-avoidance beliefs in chronic low back pain and disability","volume":"52","author":"Waddell","year":"1993","journal-title":"Pain"},{"issue":"1-2","key":"10.1016\/j.jpain.2026.106212_bib43","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0304-3959(03)00291-4","article-title":"Acceptance of pain is an independent predictor of mental well-being in patients with chronic pain: empirical evidence and reappraisal","volume":"106","author":"Viane","year":"2003","journal-title":"Pain"},{"issue":"2","key":"10.1016\/j.jpain.2026.106212_bib44","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.ejpain.2005.12.008","article-title":"The pain self-efficacy questionnaire: taking pain into account","volume":"11","author":"Nicholas","year":"2007","journal-title":"Eur J Pain"},{"issue":"12","key":"10.1016\/j.jpain.2026.106212_bib45","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0231124","article-title":"Onset hyperalgesia and offset analgesia: Transient increases or decreases of noxious thermal stimulus intensity robustly modulate subsequent perceived pain intensity","volume":"15","author":"Alter","year":"2020","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.jpain.2026.106212_bib46","doi-asserted-by":"crossref","first-page":"2205","DOI":"10.1152\/jn.00730.2001","article-title":"Transient analgesia evoked by noxious stimulus offset","volume":"87","author":"Grill","year":"2002","journal-title":"J Neurophysiol"},{"issue":"2","key":"10.1016\/j.jpain.2026.106212_bib47","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1097\/AJP.0000000000000657","article-title":"The magnitude of offset analgesia as a measure of endogenous pain modulation in healthy participants and patients with chronic pain: a systematic review and meta-analysis","volume":"35","author":"Szikszay","year":"2019","journal-title":"Clin J Pain"},{"issue":"1","key":"10.1016\/j.jpain.2026.106212_bib48","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1002\/ejp.1110","article-title":"Offset analgesia: the role of peripheral and central mechanisms","volume":"22","author":"Ligato","year":"2018","journal-title":"Eur J Pain"},{"issue":"4","key":"10.1016\/j.jpain.2026.106212_bib49","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.pain.2013.11.005","article-title":"Pain modulation profile and pain therapy: between pro- and antinociception","volume":"155","author":"Yarnitsky","year":"2014","journal-title":"Pain"},{"issue":"1","key":"10.1016\/j.jpain.2026.106212_bib50","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1111\/pme.12230","article-title":"Can quantitative sensory testing move us closer to mechanism-based pain management?","volume":"15","author":"Cruz-Almeida","year":"2014","journal-title":"Pain Med"},{"issue":"26","key":"10.1016\/j.jpain.2026.106212_bib51","doi-asserted-by":"crossref","first-page":"9689","DOI":"10.1523\/JNEUROSCI.5039-14.2015","article-title":"Individual differences in temporal summation of pain reflect pronociceptive and antinociceptive brain structure and function","volume":"35","author":"Cheng","year":"2015","journal-title":"J Neurosci"},{"issue":"3","key":"10.1016\/j.jpain.2026.106212_bib52","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.pain.2006.01.041","article-title":"Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): standardized protocol and reference values","volume":"123","author":"Rolke","year":"2006","journal-title":"Pain"},{"issue":"5","key":"10.1016\/j.jpain.2026.106212_bib53","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/j.ejpain.2010.10.001","article-title":"A psychophysical study of endogenous analgesia: the role of the conditioning pain in the induction and magnitude of conditioned pain modulation","volume":"15","author":"Nir","year":"2011","journal-title":"Eur J Pain"},{"issue":"1","key":"10.1016\/j.jpain.2026.106212_bib54","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1097\/AJP.0000000000000372","article-title":"Using a standardized clinical quantitative sensory testing battery to judge the clinical relevance of sensory differences between adjacent body areas","volume":"33","author":"Dimova","year":"2017","journal-title":"Clin J Pain"},{"issue":"3","key":"10.1016\/j.jpain.2026.106212_bib55","doi-asserted-by":"crossref","DOI":"10.1038\/tp.2013.15","article-title":"Decreased frontal regulation during pain anticipation in unmedicated subjects with major depressive disorder","volume":"3","author":"Strigo","year":"2013","journal-title":"Transl Psychiatry"},{"issue":"2","key":"10.1016\/j.jpain.2026.106212_bib56","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1089\/neu.2017.5061","article-title":"Repeated exposure to experimental pain differentiates combat traumatic brain injury with and without post-traumatic stress disorder","volume":"35","author":"Strigo","year":"2018","journal-title":"J Neurotrauma"},{"key":"10.1016\/j.jpain.2026.106212_bib57","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1162\/imag_a_00347","article-title":"Processing, evaluating, and understanding FMRI data with afni_proc.py","volume":"2","author":"Reynolds","year":"2024","journal-title":"Imaging Neurosci"},{"key":"10.1016\/j.jpain.2026.106212_bib58","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.neuroimage.2017.01.073","article-title":"Macroanatomy and 3D probabilistic atlas of the human insula","volume":"150","author":"Faillenot","year":"2017","journal-title":"Neuroimage"},{"issue":"4","key":"10.1016\/j.jpain.2026.106212_bib59","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1002\/hbm.10123","article-title":"Three-dimensional maximum probability atlas of the human brain, with particular reference to the temporal lobe","volume":"19","author":"Hammers","year":"2003","journal-title":"Hum Brain Mapp"},{"issue":"8","key":"10.1016\/j.jpain.2026.106212_bib60","first-page":"655","article-title":"How do you feel? Interoception: the sense of the physiological condition of the body","volume":"3","author":"Craig","year":"2002","journal-title":"NatRevNeurosci"},{"issue":"1","key":"10.1016\/j.jpain.2026.106212_bib61","doi-asserted-by":"crossref","first-page":"1","DOI":"10.18637\/jss.v033.i01","article-title":"Regularization Paths for Generalized Linear Models via Coordinate Descent","volume":"33","author":"Friedman","year":"2010","journal-title":"J Stat Softw"},{"key":"10.1016\/j.jpain.2026.106212_bib62","unstructured":"Team RC. R Development Core Team. R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria; 2014. Google Scholar. 2018;"},{"issue":"1","key":"10.1016\/j.jpain.2026.106212_bib63","doi-asserted-by":"crossref","first-page":"289","DOI":"10.32614\/RJ-2016-021","article-title":"mclust 5: clustering, classification and density estimation using Gaussian finite mixture models","volume":"8","author":"Scrucca","year":"2016","journal-title":"R J"},{"issue":"2","key":"10.1016\/j.jpain.2026.106212_bib64","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1093\/bioinformatics\/btr653","article-title":"Modelling time course gene expression data with finite mixtures of linear additive models","volume":"28","author":"Gr\u00fcn","year":"2012","journal-title":"Bioinformatics"},{"key":"10.1016\/j.jpain.2026.106212_bib65","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.neuroimage.2013.01.047","article-title":"Linear mixed-effects modeling approach to FMRI group analysis","volume":"73","author":"Chen","year":"2013","journal-title":"Neuroimage"},{"key":"10.1016\/j.jpain.2026.106212_bib66","doi-asserted-by":"crossref","DOI":"10.1016\/j.compbiomed.2020.103742","article-title":"Fast detection and reduction of local transient artifacts in resting-state fMRI","volume":"120","author":"Jo","year":"2020","journal-title":"Comput Biol Med"},{"issue":"2","key":"10.1016\/j.jpain.2026.106212_bib67","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.neuroimage.2010.04.246","article-title":"Mapping sources of correlation in resting state FMRI, with artifact detection and removal","volume":"52","author":"Jo","year":"2010","journal-title":"Neuroimage"},{"issue":"1","key":"10.1016\/j.jpain.2026.106212_bib68","doi-asserted-by":"crossref","first-page":"9068","DOI":"10.1038\/s41598-021-87564-6","article-title":"The ANTsX ecosystem for quantitative biological and medical imaging","volume":"11","author":"Tustison","year":"2021","journal-title":"Sci Rep"},{"key":"10.1016\/j.jpain.2026.106212_bib69","doi-asserted-by":"crossref","DOI":"10.1007\/7854_2025_588","article-title":"The Intersection of Interoception and Anticipation Related to Pain","author":"Strigo","year":"2025","journal-title":"Curr Top Behav Neurosci"},{"issue":"1","key":"10.1016\/j.jpain.2026.106212_bib70","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0163-8343(82)90026-3","article-title":"An outpatient program in behavioral medicine for chronic pain patients based on the practice of mindfulness meditation: theoretical considerations and preliminary results","volume":"4","author":"Kabat-Zinn","year":"1982","journal-title":"Gen Hosp Psychiatry"},{"key":"10.1016\/j.jpain.2026.106212_bib71","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2023.120138","article-title":"Highlight results, don't hide them: Enhance interpretation, reduce biases and improve reproducibility","volume":"274","author":"Taylor","year":"2023","journal-title":"Neuroimage"},{"issue":"1","key":"10.1016\/j.jpain.2026.106212_bib72","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1037\/a0014699","article-title":"Effect sizes for growth-modeling analysis for controlled clinical trials in the same metric as for classical analysis","volume":"14","author":"Feingold","year":"2009","journal-title":"Psychol Methods"},{"issue":"2","key":"10.1016\/j.jpain.2026.106212_bib73","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1177\/1073858413494269","article-title":"Dorsal and ventral attention systems: distinct neural circuits but collaborative roles","volume":"20","author":"Vossel","year":"2014","journal-title":"Neuroscientist"},{"key":"10.1016\/j.jpain.2026.106212_bib74","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1747-5341-6-6","article-title":"Body Awareness: a phenomenological inquiry into the common ground of mind-body therapies","volume":"6","author":"Mehling","year":"2011","journal-title":"Philos Ethics Humanit Med"},{"issue":"1-2","key":"10.1016\/j.jpain.2026.106212_bib75","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.pain.2004.03.034","article-title":"Distraction from chronic pain during a pain-inducing activity is associated with greater post-activity pain","volume":"110","author":"Goubert","year":"2004","journal-title":"Pain"},{"key":"10.1016\/j.jpain.2026.106212_bib76","doi-asserted-by":"crossref","DOI":"10.3389\/fpain.2024.1266974","article-title":"Insights into pain distraction and the impact of pain catastrophizing on pain perception during different types of distraction tasks","volume":"5","author":"Asefi Rad","year":"2024","journal-title":"Front Pain Res"},{"issue":"2","key":"10.1016\/j.jpain.2026.106212_bib77","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.neulet.2012.03.095","article-title":"Pain and emotion in the insular cortex: evidence for functional reorganization in major depression","volume":"520","author":"Mutschler","year":"2012","journal-title":"Neurosci Lett"},{"issue":"6","key":"10.1016\/j.jpain.2026.106212_bib78","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1093\/cercor\/bhp208","article-title":"Cytoarchitecture and probabilistic maps of the human posterior insular cortex","volume":"20","author":"Kurth","year":"2010","journal-title":"Cereb Cortex"},{"issue":"2","key":"10.1016\/j.jpain.2026.106212_bib79","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.neulet.2009.03.101","article-title":"Functional organization of the human anterior insular cortex","volume":"457","author":"Mutschler","year":"2009","journal-title":"Neurosci Lett"},{"issue":"6","key":"10.1016\/j.jpain.2026.106212_bib80","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/S0301-0082(02)00009-6","article-title":"Descending control of pain","volume":"66","author":"Millan","year":"2002","journal-title":"Prog Neurobiol"},{"issue":"4","key":"10.1016\/j.jpain.2026.106212_bib81","article-title":"Brainstem neuroimaging of nociception and pain circuitries","volume":"4","author":"Napadow","year":"2019","journal-title":"Pain Rep"},{"key":"10.1016\/j.jpain.2026.106212_bib82","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2020.117548","article-title":"Parallel cortical-brainstem pathways to attentional analgesia","volume":"226","author":"Oliva","year":"2021","journal-title":"NeuroImage"},{"issue":"12","key":"10.1016\/j.jpain.2026.106212_bib83","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1016\/j.biopsych.2010.04.027","article-title":"Amygdala activity, fear, and anxiety: modulation by stress","volume":"67","author":"Ressler","year":"2010","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.jpain.2026.106212_bib84","doi-asserted-by":"crossref","DOI":"10.1016\/j.neubiorev.2022.104736","article-title":"Anterior insula as a gatekeeper of executive control","volume":"139","author":"Molnar-Szakacs","year":"2022","journal-title":"Neurosci Biobehav Rev"},{"issue":"4","key":"10.1016\/j.jpain.2026.106212_bib85","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.1016\/j.neuroimage.2012.02.012","article-title":"Dissociable large-scale networks anchored in the right anterior insula subserve affective experience and attention","volume":"60","author":"Touroutoglou","year":"2012","journal-title":"Neuroimage"},{"issue":"2","key":"10.1016\/j.jpain.2026.106212_bib86","first-page":"184","article-title":"Thermosensory activation of insular cortex","volume":"3","author":"Craig","year":"2000","journal-title":"NatNeurosci"},{"key":"10.1016\/j.jpain.2026.106212_bib87","first-page":"1","article-title":"Pain mechanisms: labeled lines versus convergence in central processing","volume":"26","author":"Craig","year":"2003","journal-title":"AnnuRevNeurosci"},{"issue":"7","key":"10.1016\/j.jpain.2026.106212_bib88","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1093\/cercor\/bhq186","article-title":"Three systems of insular functional connectivity identified with cluster analysis","volume":"21","author":"Deen","year":"2011","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.jpain.2026.106212_bib89","article-title":"Probabilistic tractography recovers a rostrocaudal trajectory of connectivity variability in the human insular cortex","author":"Cerliani","year":"2011","journal-title":"Hum Brain Mapp"},{"issue":"3","key":"10.1016\/j.jpain.2026.106212_bib90","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1097\/j.pain.0000000000001737","article-title":"Alterations in pronociceptive and antinociceptive mechanisms in patients with low back pain: a systematic review with meta-analysis","volume":"161","author":"McPhee","year":"2020","journal-title":"Pain"},{"issue":"1","key":"10.1016\/j.jpain.2026.106212_bib91","doi-asserted-by":"crossref","first-page":"3894","DOI":"10.1038\/s41598-017-04009-9","article-title":"A central mechanism enhances pain perception of noxious thermal stimulus changes","volume":"7","author":"Petre","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.jpain.2026.106212_bib92","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1016\/j.neuroimage.2018.09.003","article-title":"Evidence for a spinal involvement in temporal pain contrast enhancement","volume":"183","author":"Sprenger","year":"2018","journal-title":"Neuroimage"},{"issue":"1","key":"10.1016\/j.jpain.2026.106212_bib93","article-title":"Offset analgesia and onset hyperalgesia with different stimulus ranges","volume":"6","author":"Fust","year":"2021","journal-title":"Pain Rep"},{"issue":"1","key":"10.1016\/j.jpain.2026.106212_bib94","doi-asserted-by":"crossref","first-page":"3397","DOI":"10.1038\/s41467-018-05859-1","article-title":"Brain and psychological determinants of placebo pill response in chronic pain patients","volume":"9","author":"Vachon-Presseau","year":"2018","journal-title":"Nat Commun"},{"key":"10.1016\/j.jpain.2026.106212_bib95","doi-asserted-by":"crossref","first-page":"215","DOI":"10.3389\/fnhum.2010.00215","article-title":"Attention, uncertainty, and free-energy","volume":"4","author":"Feldman","year":"2010","journal-title":"Front Hum Neurosci"},{"issue":"1","key":"10.1016\/j.jpain.2026.106212_bib96","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms12416","article-title":"Neural processes mediating contextual influences on human choice behaviour","volume":"7","author":"Rigoli","year":"2016","journal-title":"Nat Commun"},{"issue":"1","key":"10.1016\/j.jpain.2026.106212_bib97","doi-asserted-by":"crossref","first-page":"7581","DOI":"10.1038\/s41598-023-34611-z","article-title":"Unsupervised learning for prognostic validity in patients with chronic pain in transdisciplinary pain care","volume":"13","author":"Strigo","year":"2023","journal-title":"Sci Rep"},{"issue":"37","key":"10.1016\/j.jpain.2026.106212_bib98","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abj0320","article-title":"Classifying chronic pain using multidimensional pain-agnostic symptom assessments and clustering analysis","volume":"7","author":"Gilam","year":"2021","journal-title":"Sci Adv"},{"key":"10.1016\/j.jpain.2026.106212_bib99","article-title":"Understanding pain and trauma symptoms in veterans from resting-state connectivity: unsupervised modeling","volume":"3","author":"Strigo","year":"2022","journal-title":"Orig Res Front Pain Res"},{"issue":"1","key":"10.1016\/j.jpain.2026.106212_bib100","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1111\/j.2517-6161.1996.tb02080.x","article-title":"Regression shrinkage and selection via the lasso","volume":"58","author":"Tibshirani","year":"1996","journal-title":"J R Stat Soc Ser B"},{"issue":"1","key":"10.1016\/j.jpain.2026.106212_bib101","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1080\/00401706.1970.10488634","article-title":"Ridge regression: biased estimation for nonorthogonal problems","volume":"12","author":"Hoerl","year":"1970","journal-title":"Technometrics"},{"issue":"3","key":"10.1016\/j.jpain.2026.106212_bib102","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1152\/jn.00338.2011","article-title":"The organization of the human cerebral cortex estimated by intrinsic functional connectivity","volume":"106","author":"Yeo","year":"2011","journal-title":"J Neurophysiol"}],"container-title":["The Journal of Pain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1526590026000301?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1526590026000301?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T06:49:27Z","timestamp":1777618167000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1526590026000301"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":102,"alternative-id":["S1526590026000301"],"URL":"https:\/\/doi.org\/10.1016\/j.jpain.2026.106212","relation":{},"ISSN":["1526-5900"],"issn-type":[{"value":"1526-5900","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Brain mechanisms of pain anticipation in chronic low back pain: Insights into phenotypical responses to mind-body therapy","name":"articletitle","label":"Article Title"},{"value":"The Journal of Pain","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpain.2026.106212","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 Published by Elsevier Inc. on behalf of United States Association for the Study of Pain, Inc","name":"copyright","label":"Copyright"}],"article-number":"106212"}}