{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T00:10:03Z","timestamp":1793319003916,"version":"4.5.0"},"reference-count":16,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2005,12,1]],"date-time":"2005-12-01T00:00:00Z","timestamp":1133395200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,12,1]],"date-time":"2005-12-01T00:00:00Z","timestamp":1133395200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,1,13]],"date-time":"2020-01-13T00:00:00Z","timestamp":1578873600000},"content-version":"vor","delay-in-days":5156,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jpsmjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pain and Symptom Management"],"published-print":{"date-parts":[[2005,12]]},"DOI":"10.1016\/j.jpainsymman.2005.05.017","type":"journal-article","created":{"date-parts":[[2005,12,22]],"date-time":"2005-12-22T19:18:57Z","timestamp":1135279137000},"page":"570-577","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":67,"title":["When Nothing Helps: Propofol as Sedative and Antiemetic in Palliative Cancer Care"],"prefix":"10.1016","volume":"30","author":[{"given":"Staffan","family":"Lundstr\u00f6m","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulla","family":"Zachrisson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carl Johan","family":"F\u00fcrst","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpainsymman.2005.05.017_bib1","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1007\/s11912-002-0022-2","article-title":"Practical guide to palliative sedation","volume":"4","author":"Cowan","year":"2002","journal-title":"Curr Oncol Rep"},{"key":"10.1016\/j.jpainsymman.2005.05.017_bib2","first-page":"181","article-title":"Palliative sedation in the management of refractory symptoms","volume":"2","author":"Rousseau","year":"2004","journal-title":"J Support Oncol"},{"key":"10.1016\/j.jpainsymman.2005.05.017_bib3","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1378\/chest.108.2.539","article-title":"Propofol as used for sedation in the ICU","volume":"108","author":"Mirenda","year":"1995","journal-title":"Chest"},{"key":"10.1016\/j.jpainsymman.2005.05.017_bib4","first-page":"403","article-title":"Terminal sedation in palliative medicine\u2013definition and review of the literature","volume":"9","author":"Cowan","year":"2001","journal-title":"Support Care Cancer"},{"key":"10.1016\/j.jpainsymman.2005.05.017_bib5","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/0885-3924(95)00131-X","article-title":"Propofol in terminal care","volume":"10","author":"Mercadante","year":"1995","journal-title":"J Pain Symptom Manage"},{"key":"10.1016\/j.jpainsymman.2005.05.017_bib6","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/0885-3924(95)00125-5","article-title":"The use of propofol in palliative medicine","volume":"10","author":"Moyle","year":"1995","journal-title":"J Pain Symptom Manage"},{"key":"10.1016\/j.jpainsymman.2005.05.017_bib7","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1634\/theoncologist.5-1-53","article-title":"Sedation for intractable distress of a dying patient: acute palliative care and the principle of double effect","volume":"5","author":"Krakauer","year":"2000","journal-title":"Oncologist"},{"key":"10.1016\/j.jpainsymman.2005.05.017_bib8","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1097\/00043426-199611000-00008","article-title":"Continuous propofol infusion for the relief of treatment-resistant discomfort in a terminally ill pediatric patient with cancer","volume":"18","author":"Glover","year":"1996","journal-title":"J Pediatr Hematol Oncol"},{"key":"10.1016\/j.jpainsymman.2005.05.017_bib9","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/s00101-004-0787-9","article-title":"Total intravenous anesthesia with propofol and remifentanil. Results of a multicenter study of 6,161 patients","volume":"54","author":"Schmidt","year":"2005","journal-title":"Anaesthesist"},{"key":"10.1016\/j.jpainsymman.2005.05.017_bib10","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1007\/BF03015664","article-title":"Adjuvant propofol enables better control of nausea and emesis secondary to chemotherapy for breast cancer","volume":"41","author":"Borgeat","year":"1994","journal-title":"Can J Anaesth"},{"key":"10.1016\/j.jpainsymman.2005.05.017_bib11","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1097\/00000539-200104000-00027","article-title":"The effects of propofol in the area postrema of rats","volume":"92","author":"Cechetto","year":"2001","journal-title":"Anesth Analg"},{"key":"10.1016\/j.jpainsymman.2005.05.017_bib12","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1097\/00004311-200341040-00007","article-title":"The use of propofol as an antiemetic","volume":"41","author":"DeBalli","year":"2003","journal-title":"Int Anesthesiol Clin"},{"key":"10.1016\/j.jpainsymman.2005.05.017_bib13","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1213\/00000539-199701000-00035","article-title":"Subhypnotic doses of propofol do not possess antidopaminergic properties","volume":"84","author":"Borgeat","year":"1997","journal-title":"Anesth Analg"},{"key":"10.1016\/j.jpainsymman.2005.05.017_bib14","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/S0885-3924(01)00412-2","article-title":"When midazolam fails","volume":"23","author":"Cheng","year":"2002","journal-title":"J Pain Symptom Manage"},{"key":"10.1016\/j.jpainsymman.2005.05.017_bib15","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/S0885-3924(02)00683-8","article-title":"Correlation of the dose of midazolam for symptom control with administration periods: the possibility of tolerance","volume":"25","author":"Morita","year":"2003","journal-title":"J Pain Symptom Manage"},{"key":"10.1016\/j.jpainsymman.2005.05.017_bib16","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1001\/archinte.163.3.341","article-title":"Sedative use in the last week of life and the implications for end-of-life decision making","volume":"163","author":"Sykes","year":"2003","journal-title":"Arch Intern Med"}],"container-title":["Journal of Pain and Symptom Management"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0885392405005361?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0885392405005361?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T20:56:25Z","timestamp":1760129785000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0885392405005361"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,12]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2005,12]]}},"alternative-id":["S0885392405005361"],"URL":"https:\/\/doi.org\/10.1016\/j.jpainsymman.2005.05.017","relation":{},"ISSN":["0885-3924"],"issn-type":[{"value":"0885-3924","type":"print"}],"subject":[],"published":{"date-parts":[[2005,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"When Nothing Helps: Propofol as Sedative and Antiemetic in Palliative Cancer Care","name":"articletitle","label":"Article Title"},{"value":"Journal of Pain and Symptom Management","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpainsymman.2005.05.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 U.S. Cancer Pain Relief Committee. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}