{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:37:32Z","timestamp":1792784252972,"version":"4.5.0"},"reference-count":15,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T00:00:00Z","timestamp":1383264000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T00:00:00Z","timestamp":1383264000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,1,13]],"date-time":"2020-01-13T00:00:00Z","timestamp":1578873600000},"content-version":"vor","delay-in-days":2264,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"Dr. Davies's Palliative Care Research"},{"name":"Nycomed"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jpsmjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pain and Symptom Management"],"published-print":{"date-parts":[[2013,11]]},"DOI":"10.1016\/j.jpainsymman.2012.12.009","type":"journal-article","created":{"date-parts":[[2013,3,22]],"date-time":"2013-03-22T10:30:58Z","timestamp":1363948258000},"page":"619-628","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":162,"title":["Breakthrough Cancer Pain: An Observational Study of 1000 European Oncology Patients"],"prefix":"10.1016","volume":"46","author":[{"given":"Andrew","family":"Davies","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison","family":"Buchanan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovambattista","family":"Zeppetella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep","family":"Porta-Sales","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudolf","family":"Likar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Weismayr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ondrej","family":"Slama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarja","family":"Korhonen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marilene","family":"Filbet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Poulain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyriaki","family":"Mystakidou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandros","family":"Ardavanis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tony","family":"O\u2019Brien","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pauline","family":"Wilkinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Augusto","family":"Caraceni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Furio","family":"Zucco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wouter","family":"Zuurmond","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steen","family":"Andersen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anette","family":"Damkier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tove","family":"Vejlgaard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Friedemann","family":"Nauck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lukas","family":"Radbruch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl-Fredrik","family":"Sjolund","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariann","family":"Stenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpainsymman.2012.12.009_bib1","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1093\/annonc\/mdm056","article-title":"Prevalence of pain in patients with cancer: a systematic review of the past 40 years","volume":"18","author":"van den Beuken-van Everdingen","year":"2007","journal-title":"Ann Oncol"},{"key":"10.1016\/j.jpainsymman.2012.12.009_bib2","first-page":"1655","article-title":"Use of routine and breakthrough analgesia in home care","volume":"26","author":"Ferrell","year":"1999","journal-title":"Oncol Nurs Forum"},{"key":"10.1016\/j.jpainsymman.2012.12.009_bib3","first-page":"331","article-title":"The management of cancer-related breakthrough pain: recommendations of a task group of the Science Committee of the Association for Palliative Medicine of Great Britain and Ireland","volume":"13","author":"Davies","year":"2009","journal-title":"E\u00a0J Pain"},{"key":"10.1016\/j.jpainsymman.2012.12.009_bib4","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1002\/cncr.10249","article-title":"Episodic (breakthrough) pain: consensus conference of an expert working group of the European Association for Palliative Care","volume":"94","author":"Mercadante","year":"2002","journal-title":"Cancer"},{"key":"10.1016\/j.jpainsymman.2012.12.009_bib5","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0304-3959(99)00006-8","article-title":"Breakthrough pain: characteristics and impact in patients with cancer pain","volume":"81","author":"Portenoy","year":"1999","journal-title":"Pain"},{"key":"10.1016\/j.jpainsymman.2012.12.009_bib6","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0304-3959(02)00293-2","article-title":"Cancer breakthrough pain characteristics and responses to treatment at a VA medical center","volume":"101","author":"Hwang","year":"2003","journal-title":"Pain"},{"key":"10.1016\/j.jpainsymman.2012.12.009_bib7","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1517\/14656566.4.4.493","article-title":"Pharmacotherapy of cancer-related episodic pain","volume":"4","author":"Zeppetella","year":"2003","journal-title":"Expert Opin Pharmacother"},{"key":"10.1016\/j.jpainsymman.2012.12.009_bib8","series-title":"Cancer-related breakthrough pain","author":"Davies","year":"2012"},{"key":"10.1016\/j.jpainsymman.2012.12.009_bib9","first-page":"129","article-title":"Pain assessment: global use of the Brief Pain Inventory","volume":"23","author":"Cleeland","year":"1994","journal-title":"Ann Acad Med Singapore"},{"key":"10.1016\/j.jpainsymman.2012.12.009_bib10","doi-asserted-by":"crossref","first-page":"97","DOI":"10.5055\/jom.2010.0009","article-title":"Breakthrough pain in community-dwelling patients with cancer pain and non-cancer pain, part 1: prevalence and characteristics","volume":"6","author":"Portenoy","year":"2010","journal-title":"J Opioid Manag"},{"key":"10.1016\/j.jpainsymman.2012.12.009_bib11","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/S0885-3924(98)00045-1","article-title":"Characterization of breakthrough pain by hospice patients and their caregivers","volume":"16","author":"Fine","year":"1998","journal-title":"J\u00a0Pain Symptom Manage"},{"key":"10.1016\/j.jpainsymman.2012.12.009_bib12","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/0304-3959(90)90004-W","article-title":"Breakthrough pain: definition, prevalence and characteristics","volume":"41","author":"Portenoy","year":"1990","journal-title":"Pain"},{"key":"10.1016\/j.jpainsymman.2012.12.009_bib13","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0885-3924(00)00161-5","article-title":"Prevalence and characteristics of breakthrough pain in cancer patients admitted to a hospice","volume":"20","author":"Zeppetella","year":"2000","journal-title":"J\u00a0Pain Symptom Manage"},{"key":"10.1016\/j.jpainsymman.2012.12.009_bib14","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0885-3924(02)00421-9","article-title":"Breakthrough cancer pain: prevalence and characteristics in patients in Catalonia, Spain","volume":"24","author":"Gomez-Batiste","year":"2002","journal-title":"J\u00a0Pain Symptom Manage"},{"issue":"S16","key":"10.1016\/j.jpainsymman.2012.12.009_bib15","first-page":"7","article-title":"Treatment of temporal variations in chronic cancer pain","volume":"5","author":"Portenoy","year":"1997","journal-title":"Semin Oncol"}],"container-title":["Journal of Pain and Symptom Management"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0885392413001206?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0885392413001206?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T21:10:11Z","timestamp":1760130611000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0885392413001206"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11]]},"references-count":15,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["S0885392413001206"],"URL":"https:\/\/doi.org\/10.1016\/j.jpainsymman.2012.12.009","relation":{},"ISSN":["0885-3924"],"issn-type":[{"value":"0885-3924","type":"print"}],"subject":[],"published":{"date-parts":[[2013,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Breakthrough Cancer Pain: An Observational Study of 1000 European Oncology Patients","name":"articletitle","label":"Article Title"},{"value":"Journal of Pain and Symptom Management","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpainsymman.2012.12.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 U.S. Cancer Pain Relief Committee. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}