{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T00:43:38Z","timestamp":1772239418899,"version":"3.50.1"},"reference-count":22,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"vor","delay-in-days":1096,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jpsmjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pain and Symptom Management"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1016\/j.jpainsymman.2017.06.005","type":"journal-article","created":{"date-parts":[[2017,8,14]],"date-time":"2017-08-14T19:16:38Z","timestamp":1502738198000},"page":"732-736","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":60,"title":["Topical Medical Cannabis: A New Treatment for Wound Pain\u2014Three Cases of Pyoderma Gangrenosum"],"prefix":"10.1016","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8693-0617","authenticated-orcid":false,"given":"Vincent","family":"Maida","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason","family":"Corban","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpainsymman.2017.06.005_bib1","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1097\/SPC.0b013e32835ac704","article-title":"The management of wound-related procedural pain (volitional incident pain) in advanced illness","volume":"71","author":"Gallagher","year":"2013","journal-title":"Curr Opin Support Palliat Care"},{"key":"10.1016\/j.jpainsymman.2017.06.005_bib2","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1097\/SPC.0b013e32835d7ed2","article-title":"Evidence-based approach to manage persistent wound-related pain","volume":"7","author":"Woo","year":"2013","journal-title":"Curr Opin Support Palliat Care"},{"key":"10.1016\/j.jpainsymman.2017.06.005_bib3","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/0304-3959(90)90004-W","article-title":"Breakthrough pain: definition, prevalence and characteristics","volume":"41","author":"Portenoy","year":"1990","journal-title":"Pain"},{"key":"10.1016\/j.jpainsymman.2017.06.005_bib4","series-title":"Oxford textbook of palliative medicine","first-page":"438","article-title":"Difficult pain problems: an integrated approach","author":"Portenoy","year":"2004"},{"key":"10.1016\/j.jpainsymman.2017.06.005_bib5","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1111\/jphp.12284","article-title":"A\u00a0randomized, controlled, clinical pilot study assessing the analgesic effect of morphine applied topically onto split-thickness skin wounds","volume":"66","author":"Zaslansky","year":"2014","journal-title":"J\u00a0Pharm Pharmacol"},{"key":"10.1016\/j.jpainsymman.2017.06.005_bib6","doi-asserted-by":"crossref","first-page":"1920","DOI":"10.1016\/j.pain.2013.06.016","article-title":"How are topical opioids used to manage painful cutaneous lesions in palliative care? A critical review","volume":"154","author":"Graham","year":"2013","journal-title":"Pain"},{"key":"10.1016\/j.jpainsymman.2017.06.005_bib7","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1111\/j.2042-7158.2011.01252.x","article-title":"Should topical opioid analgesics be regarded as effective and safe when applied to chronic cutaneous lesions?","volume":"63","author":"Farley","year":"2011","journal-title":"J\u00a0Pharm Pharmacol"},{"key":"10.1016\/j.jpainsymman.2017.06.005_bib8","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1111\/wrr.12496","article-title":"Relationship between opioid treatment and rate of healing in chronic wounds","volume":"25","author":"Shanmugan","year":"2017","journal-title":"Wound Repair Regen"},{"key":"10.1016\/j.jpainsymman.2017.06.005_bib9","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0304-3959(03)00068-X","article-title":"Topical cannabinoid antinociception: synergy with spinal sites","volume":"105","author":"Dougrul","year":"2003","journal-title":"Pain"},{"key":"10.1016\/j.jpainsymman.2017.06.005_bib10","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/S0304-3959(03)00245-8","article-title":"Topical cannabinoid enhances topical morphine antinociception","volume":"105","author":"Yesilyurt","year":"2003","journal-title":"Pain"},{"key":"10.1016\/j.jpainsymman.2017.06.005_bib11","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/S0304-3959(02)00271-3","article-title":"Topical cannabinoid agonist, WIN55,212-2, reduces cornea-evoked trigeminal brainstem activity in the rat","volume":"99","author":"Bereiter","year":"2002","journal-title":"Pain"},{"key":"10.1016\/j.jpainsymman.2017.06.005_bib12","series-title":"Handbook of cannabis","author":"Pertwee","year":"2014"},{"key":"10.1016\/j.jpainsymman.2017.06.005_bib13","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/s40257-017-0251-7","article-title":"Pyoderma gangrenosum: an update on pathophysiology, diagnosis and treatment","volume":"18","author":"Alavi","year":"2017","journal-title":"Am J Clin Dermatol"},{"key":"10.1016\/j.jpainsymman.2017.06.005_bib14","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1177\/1534734616639172","article-title":"Pyoderma gangrenosum: a report of 27 patients","volume":"15","author":"Adisen","year":"2016","journal-title":"Int J Low Extrem Wounds"},{"key":"10.1016\/j.jpainsymman.2017.06.005_bib15","doi-asserted-by":"crossref","first-page":"285","DOI":"10.2147\/CCID.S61202","article-title":"Pyoderma gangrenosum: challenges and solutions","volume":"8","author":"Gamiero","year":"2015","journal-title":"Clin Cosmet Investig Dermatol"},{"key":"10.1016\/j.jpainsymman.2017.06.005_bib16","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1111\/j.1365-4632.2011.05451.x","article-title":"Pyoderma gangrenosum\u2014a review of 24 cases over 10 years","volume":"52","author":"Pereira","year":"2013","journal-title":"Int J Dermatol"},{"key":"10.1016\/j.jpainsymman.2017.06.005_bib17","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s11916-009-0009-x","article-title":"Pain outcomes: a brief review of instruments and techniques","volume":"13","author":"Younger","year":"2009","journal-title":"Curr Pain Headache Rep"},{"key":"10.1016\/j.jpainsymman.2017.06.005_bib18","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.tips.2009.05.004","article-title":"The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities","volume":"30","author":"Biro","year":"2009","journal-title":"Trends Pharmacol Sci"},{"key":"10.1016\/j.jpainsymman.2017.06.005_bib19","doi-asserted-by":"crossref","first-page":"e4","DOI":"10.1016\/j.jpainsymman.2016.09.003","article-title":"Medical cannabis in the palliation of malignant wounds","volume":"53","author":"Maida","year":"2017","journal-title":"J\u00a0Pain Symptom Manage"},{"key":"10.1016\/j.jpainsymman.2017.06.005_bib20","doi-asserted-by":"crossref","first-page":"2456","DOI":"10.1001\/jama.2015.6358","article-title":"Cannabinoids for medical use: a systematic review and meta-analysis","volume":"313","author":"Whiting","year":"2015","journal-title":"JAMA"},{"key":"10.1016\/j.jpainsymman.2017.06.005_bib21","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1155\/2014\/754693","article-title":"Consensus statement: pharmacological management of chronic neuropathic pain: revised consensus statement from the Canadian Pain Society","volume":"19","author":"Moulin","year":"2014","journal-title":"Pain Res Manage"},{"key":"10.1016\/j.jpainsymman.2017.06.005_bib22","doi-asserted-by":"crossref","first-page":"E46","DOI":"10.1503\/cmaj.109-5360","article-title":"Curb prescriptions to combat opioid crisis","volume":"189","author":"Vogel","year":"2017","journal-title":"CMAJ"}],"container-title":["Journal of Pain and Symptom Management"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0885392417303512?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0885392417303512?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T21:19:47Z","timestamp":1760131187000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0885392417303512"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":22,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["S0885392417303512"],"URL":"https:\/\/doi.org\/10.1016\/j.jpainsymman.2017.06.005","relation":{},"ISSN":["0885-3924"],"issn-type":[{"value":"0885-3924","type":"print"}],"subject":[],"published":{"date-parts":[[2017,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Topical Medical Cannabis: A New Treatment for Wound Pain\u2014Three Cases of Pyoderma Gangrenosum","name":"articletitle","label":"Article Title"},{"value":"Journal of Pain and Symptom Management","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpainsymman.2017.06.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}