{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,5]],"date-time":"2026-04-05T14:43:27Z","timestamp":1775400207860,"version":"3.50.1"},"reference-count":13,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2008,11,1]],"date-time":"2008-11-01T00:00:00Z","timestamp":1225497600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"published-print":{"date-parts":[[2008,11]]},"DOI":"10.1016\/j.jpba.2008.05.032","type":"journal-article","created":{"date-parts":[[2008,6,1]],"date-time":"2008-06-01T08:24:41Z","timestamp":1212308681000},"page":"829-834","source":"Crossref","is-referenced-by-count":48,"title":["Simultaneous determination of amoxicillin and ambroxol in human plasma by LC\u2013MS\/MS: Validation and application to pharmacokinetic study"],"prefix":"10.1016","volume":"48","author":[{"given":"Aidong","family":"Wen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taijun","family":"Hang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suning","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhirui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Likun","family":"Ding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun","family":"Tian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinxin","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpba.2008.05.032_bib1","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/S0140-6736(08)60071-9","volume":"371","author":"Hazir","year":"2008","journal-title":"Lancet."},{"key":"10.1016\/j.jpba.2008.05.032_bib2","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.ijantimicag.2007.07.037","volume":"30","author":"Ball","year":"2007","journal-title":"Int. J. Antimicrob. Ag."},{"key":"10.1016\/j.jpba.2008.05.032_bib3","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1002\/bdd.2510160504","volume":"16","author":"Paganin","year":"1995","journal-title":"Biopharm. Drug Dispos."},{"key":"10.1016\/j.jpba.2008.05.032_bib4","first-page":"974","volume":"31","author":"Wiemeyer","year":"1981","journal-title":"Arzneim-Forsch."},{"key":"10.1016\/j.jpba.2008.05.032_bib5","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.jpba.2004.12.031","volume":"38","author":"Hwang","year":"2005","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jpba.2008.05.032_bib6","first-page":"965","volume":"37","author":"Sp\u00e1tola","year":"1987","journal-title":"Arzneimittelforschung"},{"key":"10.1016\/j.jpba.2008.05.032_bib7","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/S0731-7085(00)00533-1","volume":"24","author":"Hein\u00e4nen","year":"2001","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jpba.2008.05.032_bib8","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.saa.2007.08.016","volume":"70","author":"Hadad","year":"2008","journal-title":"Spectrochim. Acta A Mol. Biomol. Spectrosc."},{"key":"10.1016\/j.jpba.2008.05.032_bib9","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.jpba.2007.06.019","volume":"45","author":"Foroutan","year":"2007","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jpba.2008.05.032_bib10","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.jchromb.2007.03.015","volume":"853","author":"Su","year":"2007","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.jpba.2008.05.032_bib11","first-page":"91","volume":"58","author":"Gon\u00e7alves","year":"2008","journal-title":"Arzneimittelforschung"},{"key":"10.1016\/j.jpba.2008.05.032_bib12","first-page":"40","volume":"22","author":"Hou","year":"2006","journal-title":"Chin. J. Clin. Pharmacol."},{"key":"10.1016\/j.jpba.2008.05.032_bib13","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1016\/j.jpba.2004.04.001","volume":"35","author":"Qi","year":"2004","journal-title":"J. Pharm. Biomed. Anal."}],"container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073170850800335X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073170850800335X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,28]],"date-time":"2018-12-28T04:51:05Z","timestamp":1545972665000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S073170850800335X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,11]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2008,11]]}},"alternative-id":["S073170850800335X"],"URL":"https:\/\/doi.org\/10.1016\/j.jpba.2008.05.032","relation":{},"ISSN":["0731-7085"],"issn-type":[{"value":"0731-7085","type":"print"}],"subject":[],"published":{"date-parts":[[2008,11]]}}}