{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T17:19:03Z","timestamp":1760548743899},"reference-count":47,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2009,2,1]],"date-time":"2009-02-01T00:00:00Z","timestamp":1233446400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"published-print":{"date-parts":[[2009,2]]},"DOI":"10.1016\/j.jpba.2008.11.030","type":"journal-article","created":{"date-parts":[[2008,12,1]],"date-time":"2008-12-01T04:27:34Z","timestamp":1228105654000},"page":"547-553","source":"Crossref","is-referenced-by-count":18,"title":["LC method for the therapeutic drug monitoring of lamotrigine: Evaluation of the assay performance and validation of its application in the routine area"],"prefix":"10.1016","volume":"49","author":[{"given":"L.","family":"Zuf\u00eda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Aldaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Ib\u00e1\u00f1ez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Viteri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpba.2008.11.030_bib1","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1016\/0140-6736(92)91207-O","volume":"339","author":"Brodrie","year":"1993","journal-title":"Lancet"},{"key":"10.1016\/j.jpba.2008.11.030_bib2","doi-asserted-by":"crossref","first-page":"152","DOI":"10.2165\/00003495-199346010-00009","volume":"46","author":"Goa","year":"1993","journal-title":"Drugs"},{"issue":"Suppl. 2","key":"10.1016\/j.jpba.2008.11.030_bib3","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1111\/j.1528-1157.1995.tb06002.x","volume":"36","author":"Messenheimer","year":"1995","journal-title":"Epilepsia"},{"key":"10.1016\/j.jpba.2008.11.030_bib4","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/S0378-4347(00)82290-2","volume":"531","author":"Kepetanovic","year":"1990","journal-title":"J. Chromatogr."},{"key":"10.1016\/j.jpba.2008.11.030_bib5","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1046\/j.1365-2125.1998.00769.x","volume":"46","author":"Eadie","year":"1998","journal-title":"Br. J. Clin. Pharmacol."},{"key":"10.1016\/j.jpba.2008.11.030_bib6","doi-asserted-by":"crossref","first-page":"191","DOI":"10.2165\/00003088-200038030-00001","volume":"38","author":"Perucca","year":"2000","journal-title":"Clin. Pharmacokinet."},{"key":"10.1016\/j.jpba.2008.11.030_bib7","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1007\/s002280050001","volume":"55","author":"Tomson","year":"2000","journal-title":"Eur. Clin. Pharmacol."},{"key":"10.1016\/j.jpba.2008.11.030_bib8","doi-asserted-by":"crossref","first-page":"120","DOI":"10.2165\/00003088-199631020-00004","volume":"31","author":"Yukawa","year":"1996","journal-title":"Clin. Pharmacokinet."},{"key":"10.1016\/j.jpba.2008.11.030_bib9","doi-asserted-by":"crossref","first-page":"349","DOI":"10.2165\/00023210-199707050-00003","volume":"7","author":"Johannssen","year":"1997","journal-title":"CNS Drugs"},{"key":"10.1016\/j.jpba.2008.11.030_bib10","series-title":"Therapeutic Drug Monitoring","author":"Schumacher","year":"1995"},{"key":"10.1016\/j.jpba.2008.11.030_bib11","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1097\/00007691-199610000-00001","volume":"18","author":"May","year":"1996","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.jpba.2008.11.030_bib12","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1046\/j.1365-2125.1998.00835.x","volume":"46","author":"Morris","year":"1998","journal-title":"Br. J. Clin. Pharmacol."},{"key":"10.1016\/j.jpba.2008.11.030_bib13","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1097\/00007691-199904000-00006","volume":"21","author":"Bottiger","year":"1999","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.jpba.2008.11.030_bib14","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1097\/00007691-200112000-00006","volume":"23","author":"Chan","year":"2001","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.jpba.2008.11.030_bib15","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1097\/00007691-200012000-00003","volume":"22","author":"Morris","year":"2000","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.jpba.2008.11.030_bib16","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0378-4347(96)00146-6","volume":"683","author":"Shihabi","year":"1996","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.jpba.2008.11.030_bib17","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1111\/j.1365-2125.1992.tb04079.x","volume":"33","author":"Yuen","year":"1992","journal-title":"Br. J. Clin. Pharmacol."},{"key":"10.1016\/j.jpba.2008.11.030_bib18","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1097\/00007691-199212000-00012","volume":"14","author":"Fazio","year":"1992","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.jpba.2008.11.030_bib19","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/0378-4347(95)00170-0","volume":"670","author":"Yamashita","year":"1995","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.jpba.2008.11.030_bib20","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1097\/00007691-199702000-00020","volume":"19","author":"Bartoli","year":"1997","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.jpba.2008.11.030_bib21","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1097\/00007691-199708000-00012","volume":"19","author":"Hart","year":"1997","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.jpba.2008.11.030_bib22","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1097\/00007691-199804000-00012","volume":"20","author":"Ren","year":"1998","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.jpba.2008.11.030_bib23","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0378-4347(99)00043-2","volume":"727","author":"Angelis-Stoforidis","year":"1999","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.jpba.2008.11.030_bib24","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1097\/00007691-200112000-00012","volume":"23","author":"Croci","year":"2001","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.jpba.2008.11.030_bib25","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/S0021-9673(02)01257-8","volume":"979","author":"Theurillat","year":"2002","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jpba.2008.11.030_bib26","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/0731-7085(90)80104-W","volume":"8","author":"Biddlecombe","year":"1990","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jpba.2008.11.030_bib27","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1097\/00007691-199109000-00008","volume":"13","author":"Sailstad","year":"1991","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.jpba.2008.11.030_bib28","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/S0731-7085(03)00182-1","volume":"32","author":"Boulanger","year":"2003","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jpba.2008.11.030_bib29","first-page":"101","volume":"13","author":"Hubert","year":"2003","journal-title":"S.T.P. Pharma Pratiques"},{"key":"10.1016\/j.jpba.2008.11.030_bib30","first-page":"579","volume":"36","author":"Hubert","year":"2004","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jpba.2008.11.030_bib31","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.jpba.2007.06.013","volume":"45","author":"Hubert","year":"2007","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jpba.2008.11.030_bib32","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.jpba.2007.06.032","volume":"45","author":"Hubert","year":"2007","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jpba.2008.11.030_bib33","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/j.jpba.2008.07.018","volume":"48","author":"Hubert","year":"2008","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jpba.2008.11.030_bib34","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/S0003-2670(02)00980-7","volume":"472","author":"Bugamelli","year":"2002","journal-title":"Anal. Chem. Acta"},{"key":"10.1016\/j.jpba.2008.11.030_bib35","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1097\/00007691-199708000-00016","volume":"19","author":"Watelle","year":"1997","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.jpba.2008.11.030_bib36","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1097\/00007691-199504000-00012","volume":"17","author":"Fraser","year":"1995","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.jpba.2008.11.030_bib37","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1038\/clpt.1987.193","volume":"42","author":"Cohen","year":"1987","journal-title":"Clin. Pharmacol. Ther."},{"key":"10.1016\/j.jpba.2008.11.030_bib38","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1111\/j.1365-2125.1989.tb03514.x","volume":"28","author":"Posner","year":"1989","journal-title":"Br. J. Clin. Pharmacol."},{"key":"10.1016\/j.jpba.2008.11.030_bib39","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1007\/BF02263831","volume":"36","author":"Meyler","year":"1993","journal-title":"Chromatographia"},{"key":"10.1016\/j.jpba.2008.11.030_bib40","doi-asserted-by":"crossref","first-page":"2249","DOI":"10.1002\/jssc.200700110","volume":"30","author":"Saracino","year":"2007","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.jpba.2008.11.030_bib41","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1016\/j.talanta.2006.02.010","volume":"70","author":"Gonzalez","year":"2006","journal-title":"Talanta"},{"key":"10.1016\/j.jpba.2008.11.030_bib42","unstructured":"Guidance for industry: Bioanalytical Method Validation, US Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER), Center for Biologics Evaluation and Research (CBER), May 2001."},{"key":"10.1016\/j.jpba.2008.11.030_bib43","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1002\/jps.2600810324","volume":"81","author":"Shah","year":"1992","journal-title":"J. Pharm. Sci."},{"key":"10.1016\/j.jpba.2008.11.030_bib44","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1023\/A:1007669411738","volume":"17","author":"Shah","year":"2000","journal-title":"Pharm. Res."},{"key":"10.1016\/j.jpba.2008.11.030_bib45","unstructured":"ISO5725-1, Application of the statistics-accuracy (trueness and precision) of the results and methods of measurement: Part 1, General principles and definitions, International Organization for Standardisation (ISO), Geneva, Switzerland."},{"key":"10.1016\/j.jpba.2008.11.030_bib46","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1023\/A:1015829422034","volume":"9","author":"Shah","year":"1992","journal-title":"Pharm. Res."},{"key":"10.1016\/j.jpba.2008.11.030_bib47","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1080\/03610928808829692","volume":"17","author":"Mee","year":"1988","journal-title":"Commun. Stat. Theory Method"}],"container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0731708508006225?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0731708508006225?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,23]],"date-time":"2018-12-23T20:57:52Z","timestamp":1545598672000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0731708508006225"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,2]]},"references-count":47,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2009,2]]}},"alternative-id":["S0731708508006225"],"URL":"https:\/\/doi.org\/10.1016\/j.jpba.2008.11.030","relation":{},"ISSN":["0731-7085"],"issn-type":[{"value":"0731-7085","type":"print"}],"subject":[],"published":{"date-parts":[[2009,2]]}}}