{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:20:46Z","timestamp":1761862846178},"reference-count":7,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2010,1,1]],"date-time":"2010-01-01T00:00:00Z","timestamp":1262304000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"published-print":{"date-parts":[[2010,1]]},"DOI":"10.1016\/j.jpba.2009.07.023","type":"journal-article","created":{"date-parts":[[2009,7,26]],"date-time":"2009-07-26T09:35:54Z","timestamp":1248600954000},"page":"264-267","source":"Crossref","is-referenced-by-count":14,"title":["Enantioselective determination of sibutramine and its active metabolites in human plasma"],"prefix":"10.1016","volume":"51","author":[{"given":"Wonku","family":"Kang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyoungjin","family":"Bae","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keumhan","family":"Noh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpba.2009.07.023_bib1","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1345\/aph.18319","article-title":"Sibutramine: a serotonin-norepinephrine reuptake-inhibitor for the treatment of obesity","volume":"33","author":"Luque","year":"1999","journal-title":"Ann. Pharmacother."},{"key":"10.1016\/j.jpba.2009.07.023_bib2","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1211\/0022357055678","article-title":"The stereoselective biotransformation of the anti-obesity drug sibutramine in rat liver microsomes and in primary cultures of rat hepatocytes","volume":"57","author":"Link","year":"2005","journal-title":"J. Pharm. Pharmacol."},{"key":"10.1016\/j.jpba.2009.07.023_bib3","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1093\/chromsci\/45.2.91","article-title":"Rapid and sensitive method for the determination of sibutramine active metabolites in human plasma by reversed-phase liquid chromatography\u2013tandem mass spectroscopy","volume":"45","author":"Bhatt","year":"2007","journal-title":"J. Chromatogr. Sci."},{"key":"10.1016\/j.jpba.2009.07.023_bib4","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.jpba.2009.04.024","article-title":"Analysis of enantiomers of sibutramine and its metabolites in rat plasma by liquid chromatography-mass spectrometry using a chiral stationary-phase column","volume":"50","author":"Bae","year":"2009","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jpba.2009.07.023_bib5","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0014-2999(00)00216-8","article-title":"Enantioselective behavioral effects of sibutramine metabolites","volume":"397","author":"Glick","year":"2000","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.jpba.2009.07.023_bib6","doi-asserted-by":"crossref","first-page":"4477","DOI":"10.1016\/S0957-4166(99)00511-X","article-title":"First preparation of enantiometrically pure sibutramine and its major metabolite, and determination of their absolute configuration by single crystal X-ray analysis","volume":"10","author":"Fang","year":"1999","journal-title":"Tetrahedron: Asymmetry"},{"key":"10.1016\/j.jpba.2009.07.023_bib7","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1002\/jms.1082","article-title":"Metabolite profile of sibutramine in human urine: a liquid chromatography\u2013electrospray ionization mass spectrometric study","volume":"41","author":"Link","year":"2006","journal-title":"J. Mass Spectrom."}],"container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0731708509004798?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0731708509004798?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,18]],"date-time":"2018-12-18T00:22:02Z","timestamp":1545092522000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0731708509004798"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,1]]},"references-count":7,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,1]]}},"alternative-id":["S0731708509004798"],"URL":"https:\/\/doi.org\/10.1016\/j.jpba.2009.07.023","relation":{},"ISSN":["0731-7085"],"issn-type":[{"value":"0731-7085","type":"print"}],"subject":[],"published":{"date-parts":[[2010,1]]}}}