{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T15:58:03Z","timestamp":1767974283194,"version":"3.49.0"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"published-print":{"date-parts":[[2012,3]]},"DOI":"10.1016\/j.jpba.2011.12.029","type":"journal-article","created":{"date-parts":[[2012,1,5]],"date-time":"2012-01-05T06:03:26Z","timestamp":1325743406000},"page":"33-41","source":"Crossref","is-referenced-by-count":49,"special_numbering":"C","title":["Comparative HPLC methods for \u03b2-blockers separation using different types of chiral stationary phases in normal phase and polar organic phase elution modes. Analysis of propranolol enantiomers in natural waters"],"prefix":"10.1016","volume":"62","author":[{"given":"Sonia","family":"Morante-Zarcero","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel","family":"Sierra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpba.2011.12.029_bib0005","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0165-022X(02)00143-4","article-title":"Stereoselective chromatography of cardiovascular drugs: an update","volume":"54","author":"Jacek","year":"2002","journal-title":"J. Biochem. Biophys. Methods"},{"key":"10.1016\/j.jpba.2011.12.029_bib0010","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1016\/j.watres.2007.01.004","article-title":"Elimination of \u03b2-blockers in sewage treatment plants","volume":"41","author":"Maurer","year":"2007","journal-title":"Water Res."},{"key":"10.1016\/j.jpba.2011.12.029_bib0015","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/S0378-4274(02)00041-3","article-title":"Occurrence, fate and removal of pharmaceutical residues in the aquatic environment: a review of recent research data","volume":"131","author":"Heberer","year":"2002","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.jpba.2011.12.029_bib0020","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0021-9673(01)01266-3","article-title":"Pharmaceuticals in groundwaters analytical methods and results of a monitoring program in Baden-W\u00fcrttemberg, Germany","volume":"938","author":"Sacher","year":"2001","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jpba.2011.12.029_bib0025","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.chroma.2006.07.033","article-title":"Stereoisomer quantification of the \u03b2-blocker drugs atenolol, metoprolol and propranolol in wastewaters by chiral high-performance liquid chromatography\u2013tandem mass spectrometry","volume":"1131","author":"Nikolai","year":"2006","journal-title":"J Chromatogr. A"},{"key":"10.1016\/j.jpba.2011.12.029_bib0105","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1021\/cr00092a006","article-title":"Considerations of chiral recognition relevant to the liquid chromatography separation of enantiomers","volume":"89","author":"Pirkle","year":"1989","journal-title":"Chem. Rev."},{"key":"10.1016\/j.jpba.2011.12.029_bib0110","series-title":"Chirality in Drug Research","author":"Maier","year":"2006"},{"key":"10.1016\/j.jpba.2011.12.029_bib0115","series-title":"Chiral Separations: Macrocyclic Antibiotics in Chromatography: Liquid Encyclopedia of Separation Science","author":"Xiao","year":"2007"},{"key":"10.1016\/j.jpba.2011.12.029_bib0045","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1002\/bmc.1130070602","article-title":"Enantioselective bioanalysis of \u03b2-blocking agents: focus on atenolol, betaxolol, carvedilol, metoprolol, pindolol, propranolol and sotalol","volume":"7","author":"Egginger","year":"1993","journal-title":"Biomed. Chromatogr."},{"key":"10.1016\/j.jpba.2011.12.029_bib0050","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1002\/(SICI)1099-0801(199905)13:3<197::AID-BMC822>3.0.CO;2-T","article-title":"Recent chromatography and electrophoretic enantioseparations of cardiovascular drugs","volume":"13","author":"Jacek","year":"1999","journal-title":"Biomed. Chromatogr."},{"key":"10.1016\/j.jpba.2011.12.029_bib0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jchromb.2007.11.034","article-title":"Recent developments of enantioseparation techniques for adrenergic drugs using liquid chromatography and capillary electrophoresis: a review","volume":"862","author":"Wang","year":"2008","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.jpba.2011.12.029_bib0060","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.chroma.2007.09.010","article-title":"Stereoselective analysis of wastewaters \u2013 derived \u03b2-blockers, selective serotonin re-uptake inhibitors and salbutamol by high-performance liquid chromatography\u2013tandem mass spectrometry","volume":"1170","author":"MacLeod","year":"2007","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jpba.2011.12.029_bib0065","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1365\/s10337-006-0097-2","article-title":"Molecularly imprinted polymers for solid phase extraction","volume":"64","author":"Qiao","year":"2006","journal-title":"Chromatographia"},{"key":"10.1016\/j.jpba.2011.12.029_bib0070","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0021-9673(00)00501-X","article-title":"Polysaccharide-based chiral stationary phases for high-performance liquid chromatographic enantioseparation","volume":"906","author":"Yashima","year":"2001","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jpba.2011.12.029_bib0075","first-page":"345","article-title":"The impact of stereochemistry on drug development and use","volume":"vol. 142","author":"Yashima","year":"1997"},{"key":"10.1016\/j.jpba.2011.12.029_bib0080","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0021-9673(01)01573-4","article-title":"Screening approach for chiral separation of pharmaceuticals. Part I. Normal-phase liquid chromatography","volume":"947","author":"Perrin","year":"2002","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jpba.2011.12.029_bib0085","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0021-9673(01)01059-7","article-title":"Effect of mobile phase amine additives on enantioselectivity for phenylalanine analogs","volume":"927","author":"Ye","year":"2001","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jpba.2011.12.029_bib0090","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.jpba.2010.10.020","article-title":"Development and validation of a LC method for the enantiomeric purity determination of S-ropivacaine in a pharmaceutical formulation using a recently commercialized cellulose-based chiral stationary phase and polar non-aqueous mobile phase","volume":"54","author":"Dossou","year":"2011","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jpba.2011.12.029_bib0095","doi-asserted-by":"crossref","first-page":"2819","DOI":"10.1081\/JLC-100101234","article-title":"Comparative study of amylose and cellulose derivatized chiral stationary phases in the reversed-phase mode","volume":"23","author":"Kazusaki","year":"2000","journal-title":"J. Liq. Chromatogr. Ref. Technol."},{"key":"10.1016\/j.jpba.2011.12.029_bib0100","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.trac.2007.03.005","article-title":"LC\u2013MS analysis of basic pharmaceuticals (beta-blockers and anti-ulcer agents) in wastewater and surface water","volume":"26","author":"Hernando","year":"2007","journal-title":"Trends Anal. Chem."}],"container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0731708511007369?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0731708511007369?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,27]],"date-time":"2018-11-27T03:28:08Z","timestamp":1543289288000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0731708511007369"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3]]},"references-count":20,"alternative-id":["S0731708511007369"],"URL":"https:\/\/doi.org\/10.1016\/j.jpba.2011.12.029","relation":{},"ISSN":["0731-7085"],"issn-type":[{"value":"0731-7085","type":"print"}],"subject":[],"published":{"date-parts":[[2012,3]]}}}