{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T19:11:11Z","timestamp":1780341071516,"version":"3.54.1"},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2012,11,1]],"date-time":"2012-11-01T00:00:00Z","timestamp":1351728000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Spanish Ministerio de Educaci\u00f3n y Ciencia (MICINN)"},{"name":"FEDER Program"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"published-print":{"date-parts":[[2012,11]]},"DOI":"10.1016\/j.jpba.2012.06.033","type":"journal-article","created":{"date-parts":[[2012,7,2]],"date-time":"2012-07-02T10:01:26Z","timestamp":1341223286000},"page":"476-484","source":"Crossref","is-referenced-by-count":32,"special_numbering":"C","title":["Determination of essential amino acids in human serum by a targeting method based on automated SPE\u2013LC\u2013MS\/MS: Discrimination between artherosclerotic patients"],"prefix":"10.1016","volume":"70","author":[{"given":"M.","family":"Calder\u00f3n-Santiago","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Priego-Capote","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.G.","family":"Galache-Osuna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.D.","family":"Luque de Castro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpba.2012.06.033_bib0005","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00726-009-0269-0","article-title":"Amino acids: metabolism, functions, and nutrition","volume":"37","author":"Wu","year":"2009","journal-title":"Amino Acids"},{"key":"10.1016\/j.jpba.2012.06.033_bib0010","first-page":"209","article-title":"Oxidative stress and ischemic myocardial syndromes","volume":"15","author":"Misra","year":"2009","journal-title":"Med. Sci. Monit."},{"key":"10.1016\/j.jpba.2012.06.033_bib0015","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/s10557-011-6341-5","article-title":"Oxidized LDL, LOX-1 and atherosclerosis","volume":"25","author":"Mitra","year":"2011","journal-title":"Cardiovasc. Drugs Ther."},{"key":"10.1016\/j.jpba.2012.06.033_bib0020","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1016\/j.freeradbiomed.2011.05.004","article-title":"Reactive oxygen species in cardiovascular disease","volume":"51","author":"Sugamura","year":"2011","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.jpba.2012.06.033_bib0025","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1152\/physrev.00047.2003","article-title":"Role of oxidative modifications in atherosclerosis","volume":"84","author":"Stocker","year":"2004","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.jpba.2012.06.033_bib0030","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1111\/j.1538-7836.2004.01085.x","article-title":"Oxidative stress in atherogenesis and arterial thrombosis: the disconnect between cellular studies and clinical outcomes","volume":"3","author":"Madamanchi","year":"2005","journal-title":"J. Thromb. Haemost."},{"key":"10.1016\/j.jpba.2012.06.033_bib0035","first-page":"18","article-title":"The treatment of coronary heart disease: an update\u2014Part 1. An overview of the risk factors for cardiovascular disease","volume":"17","author":"Elisaf","year":"2001","journal-title":"Curr. Med. Res. Opin."},{"key":"10.1016\/j.jpba.2012.06.033_bib0040","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.1467-789X.2007.00437.x","article-title":"International strategies to address obesity","volume":"9","author":"Hill","year":"2008","journal-title":"Obes. Rev."},{"key":"10.1016\/j.jpba.2012.06.033_bib0045","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1152\/ajpendo.00134.2007","article-title":"Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism","volume":"293","author":"She","year":"2007","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.jpba.2012.06.033_bib0050","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1039\/b925612a","article-title":"Untargeted metabolic profiling reveals potential biomarkers in myocardial infarction and its application","volume":"6","author":"Yao","year":"2010","journal-title":"Mol. Biosyst."},{"key":"10.1016\/j.jpba.2012.06.033_bib0055","doi-asserted-by":"crossref","first-page":"3503","DOI":"10.1172\/JCI35111","article-title":"Metabolite profiling of blood from individuals undergoing planned myocardial infarction reveals early markers of myocardial injury","volume":"118","author":"Lewis","year":"2008","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.jpba.2012.06.033_bib0060","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1016\/j.cca.2011.02.015","article-title":"HPLC-FLD determination of serum aromatic amino acids: application in chronic kidney disease patients","volume":"412","author":"Li","year":"2011","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.jpba.2012.06.033_bib0065","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1007\/s10337-011-2112-5","article-title":"HPLC with in-capillary optical fiber laser-induced fluorescence detection of picomolar amounts of amino acids by precolumn fluorescence derivatization with fluorescein isothiocyanate","volume":"74","author":"He","year":"2011","journal-title":"Chromatographia"},{"key":"10.1016\/j.jpba.2012.06.033_bib0070","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.aca.2011.07.042","article-title":"One-pot labeling-based capillary zone electrophoresis for separation of amino acid mixture and assay of biofluids","volume":"703","author":"Song","year":"2011","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.jpba.2012.06.033_bib0075","doi-asserted-by":"crossref","first-page":"2054","DOI":"10.1021\/ac001243c","article-title":"Derivatization and fluorescence detection of amino acids and peptides with 9-fluorenylmethyl chloroformate on the surface of a solid adsorbent","volume":"73","author":"Shangguan","year":"2001","journal-title":"Anal. Chem."},{"key":"10.1016\/j.jpba.2012.06.033_bib0080","doi-asserted-by":"crossref","first-page":"6248","DOI":"10.1016\/j.chroma.2011.07.011","article-title":"Electromembrane extraction of amino acids from body fluids followed by capillary electrophoresis with capacitively coupled contactless conductivity detection","volume":"1218","author":"Strieglerova","year":"2011","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jpba.2012.06.033_bib0085","doi-asserted-by":"crossref","first-page":"3275","DOI":"10.1007\/s00216-011-5445-x","article-title":"Optimization of dynamic pH junction for the sensitive determination of amino acids in urine by capillary electrophoresis","volume":"401","author":"Tak","year":"2011","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.jpba.2012.06.033_bib0090","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1093\/clinchem\/43.8.1421","article-title":"Amino acid determination in biological fluids by automated ion-exchange chromatography: performance of Hitachi L-8500A","volume":"43","author":"LeBoucher","year":"1997","journal-title":"Clin. Chem."},{"key":"10.1016\/j.jpba.2012.06.033_bib0095","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1677\/JOE-10-0060","article-title":"An online solid-phase extraction\u2013liquid chromatography\u2013tandem mass spectrometry method to study the presence of thyronamines in plasma and tissue and their putative conversion from (13)C(6)-thyroxine","volume":"206","author":"Ackermans","year":"2010","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.jpba.2012.06.033_bib0100","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1093\/jat\/32.8.570","article-title":"Rapid analysis of cocaine and metabolites in urine using a completely automated solid-phase extraction\u2013high-performance liquid chromatography\u2013tandem mass spectrometry method","volume":"32","author":"Jagerdeo","year":"2008","journal-title":"J. Anal. Toxicol."},{"key":"10.1016\/j.jpba.2012.06.033_bib0105","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.jchromb.2008.08.026","article-title":"An automated SPE\/LC\/MS\/MS method for the analysis of cocaine and metabolites in whole blood","volume":"874","author":"Jagerdeo","year":"2008","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.jpba.2012.06.033_bib0110","series-title":"Handbook of Chemometrics and Qualimetrics. Part A","author":"Massart","year":"1997"},{"key":"10.1016\/j.jpba.2012.06.033_bib0115","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/S0899-9007(02)00780-3","article-title":"Plasma amino acid levels with a note on membrane transport: characteristics, regulation, and metabolic significance","volume":"18","author":"Cynober","year":"2002","journal-title":"Nutrition"},{"key":"10.1016\/j.jpba.2012.06.033_bib0120","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1054\/clnu.1999.0131","article-title":"Methods, who cares?","volume":"19","author":"Wernerman","year":"2000","journal-title":"Clin. Nutr."},{"key":"10.1016\/j.jpba.2012.06.033_bib0125","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/j.1365-2796.2006.01663.x","article-title":"Abnormalities of whole body protein turnover, muscle metabolism and levels of metabolic hormones in patients with chronic heart failure","volume":"260","author":"Norrelund","year":"2006","journal-title":"J. Intern. Med."}],"container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0731708512003652?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0731708512003652?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,7,10]],"date-time":"2020-07-10T04:55:48Z","timestamp":1594356948000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0731708512003652"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11]]},"references-count":25,"alternative-id":["S0731708512003652"],"URL":"https:\/\/doi.org\/10.1016\/j.jpba.2012.06.033","relation":{},"ISSN":["0731-7085"],"issn-type":[{"value":"0731-7085","type":"print"}],"subject":[],"published":{"date-parts":[[2012,11]]}}}