{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T01:28:41Z","timestamp":1790126921428,"version":"4.0.1"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2013,1,1]],"date-time":"2013-01-01T00:00:00Z","timestamp":1356998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"published-print":{"date-parts":[[2013,1]]},"DOI":"10.1016\/j.jpba.2012.09.006","type":"journal-article","created":{"date-parts":[[2012,9,18]],"date-time":"2012-09-18T14:18:03Z","timestamp":1347977883000},"page":"65-73","source":"Crossref","is-referenced-by-count":28,"special_numbering":"C","title":["Chromatographic retention parameters in correlation analysis with in silico biological descriptors of a novel series of N-phenyl-3-methyl succinimide derivatives"],"prefix":"10.1016","volume":"72","author":[{"given":"Nada","family":"Perisic-Janjic","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roman","family":"Kaliszan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natasa","family":"Milosevic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gordana","family":"Uscumlic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nebojsa","family":"Banjac","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpba.2012.09.006_bib0005","doi-asserted-by":"crossref","first-page":"4921","DOI":"10.1016\/j.bmc.2008.03.037","article-title":"Design, synthesis, and anticonvulsant activity of N-phenylamino derivatives of 3,3-dialkyl-pyrrolidine-2,5-diones and hexahydro-isoindole-1,3-diones","volume":"16","author":"Kaminski","year":"2008","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.jpba.2012.09.006_bib0010","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/S0014-827X(99)00033-6","article-title":"Synthesis, physicochemical and anticonvulsant properties of new N-pyridyl derivatives of 3-phenyl- and 3,3-diphenyl succinimides","volume":"54","author":"Obniska","year":"1999","journal-title":"Farmaco"},{"key":"10.1016\/j.jpba.2012.09.006_bib0015","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1021\/mp100373d","article-title":"Reversed-phase TLC and HPLC tetention data in correlation studies with in silico molecular descriptors and druglikness properties of newly sinthesized anticonvulsant succinimide derivatives","volume":"8","author":"Perisic Janjic","year":"2011","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.jpba.2012.09.006_bib0020","first-page":"9","article-title":"Synthesis of 3,3-diarylpyrrolidines from diaryl ketones","author":"Katritzky","year":"2003","journal-title":"ARKIVOC, Issue in Honor of Prof. G\u00e1bor Bern\u00e1th"},{"key":"10.1016\/j.jpba.2012.09.006_bib0025","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/S0960-894X(97)00143-1","article-title":"Design of dual acting anticonvulsant\u2013antimuscarinic succinimide and hydantoin derivatives","volume":"7","author":"Hudkins","year":"1997","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.jpba.2012.09.006_bib0030","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1021\/jm00367a015","article-title":"Structure\u2013activity relationships of phenytoin-like anticonvulsant drugs","volume":"27","author":"Poupaert","year":"1984","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.jpba.2012.09.006_bib0035","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1186\/1752-153X-5-62","article-title":"Solvent effects on the structure\u2013property relationship of anticonvulsant hydantoin derivatives: a solvatochromic analysis","volume":"5","author":"Trisovic","year":"2011","journal-title":"Chem. Cent. J."},{"key":"10.1016\/j.jpba.2012.09.006_bib0040","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1038\/nrd1086","article-title":"Hit and lead generation: beyond high-throughput screening","volume":"2","author":"Bleicher","year":"2003","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.jpba.2012.09.006_bib0045","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0163-7258(99)00052-2","article-title":"Pharmacokinetic profile of levetiracetam: toward ideal characteristics","volume":"85","author":"Patsalosa","year":"2000","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.jpba.2012.09.006_bib0050","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1038\/nrd1032","article-title":"ADMET in silico modelling: towards prediction paradise?","volume":"2","author":"van de Waterbeemd","year":"2003","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.jpba.2012.09.006_bib0055","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.chroma.2007.03.108","article-title":"Quantitative structure\u2013(chromatographic) retention relationships","volume":"1158","author":"Heberger","year":"2007","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jpba.2012.09.006_bib0060","doi-asserted-by":"crossref","first-page":"3212","DOI":"10.1021\/cr068412z","article-title":"QSRR: quantitative structure\u2013(chromatographic) retention relationships","volume":"107","author":"Kaliszan","year":"2007","journal-title":"Chem. Rev."},{"key":"10.1016\/j.jpba.2012.09.006_bib0065","doi-asserted-by":"crossref","first-page":"381","DOI":"10.2174\/0929867033368268","article-title":"Chromatographic retention parameters in medicinal chemistry and molecular pharmacology","volume":"10","author":"Nasal","year":"2003","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.jpba.2012.09.006_bib0070","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.steroids.2004.11.002","article-title":"HPTLC chromatography of androstene derivates. Application of normal phase thin-layer chromatographic retention data in QSAR studies","volume":"70","author":"Perisic -Janjic","year":"2005","journal-title":"Steroids"},{"key":"10.1016\/j.jpba.2012.09.006_bib0075","doi-asserted-by":"crossref","first-page":"439","DOI":"10.2298\/HEMIND110224030B","article-title":"Succinimides: synthesis, properties and anticonvulsant activity","volume":"65","author":"Banjac","year":"2011","journal-title":"Chem. Ind."},{"key":"10.1016\/j.jpba.2012.09.006_bib0080","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0021-9673(01)01278-X","article-title":"Mechanistic molecular model of liquid\u2013solid chromatography retention\u2013eluent composition relationship","volume":"965","author":"Soczewi\u0144ski","year":"2002","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jpba.2012.09.006_bib0085","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1365\/s10337-004-0252-6","article-title":"Evaluation of the lipophilicity of some dehydroepiandrostene derivates using RP-18 HPTLC chromatography","volume":"60","author":"Peri\u0161i\u0107-Janji\u0107","year":"2004","journal-title":"Chromatographia"},{"key":"10.1016\/j.jpba.2012.09.006_bib0090","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1093\/bib\/3.1.73","article-title":"The role of quantitative structure activity relationship (QSAR) in biomolecular discovery","volume":"3","author":"Winkler","year":"2002","journal-title":"Brief. Bioinform."},{"key":"10.1016\/j.jpba.2012.09.006_bib0105","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1016\/j.jpba.2010.06.024","article-title":"Revisiting thin-layer chromatography as a lipophilicity determination tool \u2013 a comparative study on several techniques with a model solute set","volume":"53","author":"Komsta","year":"2010","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jpba.2012.09.006_bib0110","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1080\/10826079308021688","article-title":"Lipophilicity determination of some monoamine oxidase inhibitors: the effect of methanol and ammonium chloride","volume":"16","author":"Cserh\u00e1ti","year":"1993","journal-title":"J. Liq. Chromatogr."},{"key":"10.1016\/j.jpba.2012.09.006_bib0115","series-title":"Separation Methods in Drug Synthesis and Purification","first-page":"535","article-title":"Measurements of physical properties for drug design in industry","author":"Valk\u00f3","year":"2000"},{"key":"10.1016\/j.jpba.2012.09.006_bib0120","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0169-409X(00)00129-0","article-title":"Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings","volume":"46","author":"Lipinski","year":"2001","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.jpba.2012.09.006_bib0125","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.ejps.2008.03.001","article-title":"Passive oral drug absorption can be predicted more reliably by experimental than computational models \u2013 fact or myth","volume":"34","author":"Linnankoski","year":"2008","journal-title":"Eur. J. Pharm. Sci."},{"key":"10.1016\/j.jpba.2012.09.006_bib0130","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.ijpharm.2006.03.043","article-title":"QSPR models for the prediction of apparent volume of distribution","volume":"319","author":"Ghafourian","year":"2006","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.jpba.2012.09.006_bib0135","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.ejps.2010.10.011","article-title":"Use of unbound volumes of drug distribution in pharmacokinetic calculations","volume":"42","author":"Stepensky","year":"2011","journal-title":"Eur. J. Pharm. Sci."},{"key":"10.1016\/j.jpba.2012.09.006_bib0140","doi-asserted-by":"crossref","first-page":"502","DOI":"10.2174\/157018007781788480","article-title":"In Silico Prediction of Human Plasma Protein Binding Using Hologram QSAR","volume":"4","author":"Modaa","year":"2007","journal-title":"QSAR Lett. Drug Des. Discov."},{"key":"10.1016\/j.jpba.2012.09.006_bib0145","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/nrd2368","article-title":"Modelling of the blood\u2013brain barrier in drug discovery and development","volume":"6","author":"Cecchelli","year":"2007","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.jpba.2012.09.006_bib0150","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1002\/jps.2600760902","article-title":"Hydrophobicity and central nervous system agents: on the principle of minimal hydrophobicity in drug design","volume":"76","author":"Hansch","year":"1987","journal-title":"J. Pharm. Sci."}],"container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0731708512004955?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0731708512004955?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,11,20]],"date-time":"2018-11-20T13:25:30Z","timestamp":1542720330000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0731708512004955"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":28,"alternative-id":["S0731708512004955"],"URL":"https:\/\/doi.org\/10.1016\/j.jpba.2012.09.006","relation":{},"ISSN":["0731-7085"],"issn-type":[{"value":"0731-7085","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1]]}}}