{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T09:44:43Z","timestamp":1780393483972,"version":"3.54.1"},"reference-count":38,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Tunisian Ministry of Higher Education and Scientific Research"},{"DOI":"10.13039\/501100004837","name":"Spanish Ministry of Science and Innovation","doi-asserted-by":"crossref","award":["AGL2011-29857-C03-02"],"award-info":[{"award-number":["AGL2011-29857-C03-02"]}],"id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004837","name":"Spanish Ministry of Science and Innovation","doi-asserted-by":"crossref","award":["AGL2011-29857-C03-03"],"award-info":[{"award-number":["AGL2011-29857-C03-03"]}],"id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004837","name":"Spanish Ministry of Science and Innovation","doi-asserted-by":"crossref","award":["BFU2014-5243-C3-1-R"],"award-info":[{"award-number":["BFU2014-5243-C3-1-R"]}],"id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004837","name":"Spanish Ministry of Science and Innovation","doi-asserted-by":"crossref","award":["AP2007-03246"],"award-info":[{"award-number":["AP2007-03246"]}],"id":[{"id":"10.13039\/501100004837","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Andalusian Regional Government Council of Innovation and Science","award":["P10-FQM-6563"],"award-info":[{"award-number":["P10-FQM-6563"]}]},{"name":"Andalusian Regional Government Council of Innovation and Science","award":["P11-CTS-7625"],"award-info":[{"award-number":["P11-CTS-7625"]}]},{"DOI":"10.13039\/501100003359","name":"Generalitat Valenciana","doi-asserted-by":"publisher","award":["PROMETEO\/2012\/007"],"award-info":[{"award-number":["PROMETEO\/2012\/007"]}],"id":[{"id":"10.13039\/501100003359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003359","name":"Generalitat Valenciana","doi-asserted-by":"publisher","award":["ACOMP\/2013\/093"],"award-info":[{"award-number":["ACOMP\/2013\/093"]}],"id":[{"id":"10.13039\/501100003359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006301","name":"CIBER","doi-asserted-by":"publisher","award":["CB12\/03\/30038"],"award-info":[{"award-number":["CB12\/03\/30038"]}],"id":[{"id":"10.13039\/100006301","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"published-print":{"date-parts":[[2015,2]]},"DOI":"10.1016\/j.jpba.2014.11.048","type":"journal-article","created":{"date-parts":[[2014,12,11]],"date-time":"2014-12-11T14:32:17Z","timestamp":1418308337000},"page":"156-162","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":41,"special_numbering":"C","title":["Differential metabolomic analysis of the potential antiproliferative mechanism of olive leaf extract on the JIMT-1 breast cancer cell line"],"prefix":"10.1016","volume":"105","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8113-0795","authenticated-orcid":false,"given":"Enrique","family":"Barraj\u00f3n-Catal\u00e1n","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amani","family":"Taamalli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa","family":"Quirantes-Pin\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Roldan-Segura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Arr\u00e1ez-Rom\u00e1n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Segura-Carretero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vicente","family":"Micol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mokhtar","family":"Zarrouk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpba.2014.11.048_bib0005","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.fct.2012.10.004","volume":"51","author":"Joven","year":"2013","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.jpba.2014.11.048_bib0010","doi-asserted-by":"crossref","first-page":"555","DOI":"10.4161\/cc.23756","volume":"12","author":"Menendez","year":"2013","journal-title":"Cell Cycle"},{"key":"10.1016\/j.jpba.2014.11.048_bib0015","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.jpba.2009.06.021","volume":"51","author":"Garcia-Villalba","year":"2010","journal-title":"J. Pharmaceut. Biomed."},{"key":"10.1016\/j.jpba.2014.11.048_bib0020","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1038\/nrc1189","volume":"3","author":"Surh","year":"2003","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.jpba.2014.11.048_bib0025","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1055\/s-0028-1084205","volume":"74","author":"Sannella","year":"2008","journal-title":"Planta Med."},{"key":"10.1016\/j.jpba.2014.11.048_bib0030","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/S0308-8146(99)00221-6","volume":"68","author":"Benavente-Garcia","year":"2000","journal-title":"Food Chem."},{"key":"10.1016\/j.jpba.2014.11.048_bib0035","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1046\/j.1439-0507.2003.00859.x","volume":"46","author":"Markin","year":"2003","journal-title":"Mycoses"},{"key":"10.1016\/j.jpba.2014.11.048_bib0040","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.cbi.2008.08.014","volume":"176","author":"Jemai","year":"2008","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.jpba.2014.11.048_bib0045","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.antiviral.2005.02.005","volume":"66","author":"Micol","year":"2005","journal-title":"Antivir. Res."},{"key":"10.1016\/j.jpba.2014.11.048_bib0050","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/j.bbrc.2005.06.161","volume":"334","author":"Hamdi","year":"2005","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.jpba.2014.11.048_bib0055","doi-asserted-by":"crossref","first-page":"20947","DOI":"10.3402\/ljm.v8i0.20947","volume":"8","author":"Dub","year":"2013","journal-title":"Lib. J. Med."},{"key":"10.1016\/j.jpba.2014.11.048_bib0060","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/S0924-2244(00)00068-6","volume":"11","author":"Saija","year":"2000","journal-title":"Trends Food Sci. Tech."},{"key":"10.1016\/j.jpba.2014.11.048_bib0065","first-page":"239","volume":"15","author":"Abaza","year":"2008","journal-title":"Anim. Cell Technol.: Bas. Appl. Asp."},{"key":"10.1016\/j.jpba.2014.11.048_bib0070","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1007\/s00216-010-3604-0","volume":"397","author":"Fu","year":"2010","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.jpba.2014.11.048_bib0075","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.fct.2010.10.014","volume":"49","author":"Bouallagui","year":"2011","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.jpba.2014.11.048_bib0080","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1016\/j.fct.2012.02.090","volume":"50","author":"Taamalli","year":"2012","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.jpba.2014.11.048_bib0085","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1111\/j.1753-4887.2009.00248.x","volume":"67","author":"El","year":"2009","journal-title":"Nutr. Rev."},{"key":"10.1016\/j.jpba.2014.11.048_bib0090","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1002\/mnfr.201200795","volume":"57","author":"de Bock","year":"2013","journal-title":"Mol. Nutr. Food Res."},{"key":"10.1016\/j.jpba.2014.11.048_bib0095","doi-asserted-by":"crossref","first-page":"6190","DOI":"10.1021\/jf501414h","volume":"62","author":"Ahmad-Qasem","year":"2014","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.jpba.2014.11.048_bib0100","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.foodres.2012.10.028","volume":"50","author":"Ahmad-Qasem","year":"2013","journal-title":"Food Res. Int."},{"key":"10.1016\/j.jpba.2014.11.048_bib0105","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1158\/1535-7163.1585.3.12","volume":"3","author":"Tanner","year":"2004","journal-title":"Mol. Cancer Ther."},{"key":"10.1016\/j.jpba.2014.11.048_bib0110","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.ejphar.2010.10.063","volume":"651","author":"Attoub","year":"2011","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.jpba.2014.11.048_bib0115","doi-asserted-by":"crossref","first-page":"819","DOI":"10.3892\/or.2012.2158","volume":"29","author":"Jeon","year":"2013","journal-title":"Oncol. Rep."},{"key":"10.1016\/j.jpba.2014.11.048_bib0120","doi-asserted-by":"crossref","first-page":"480","DOI":"10.18632\/aging.100472","volume":"4","author":"Corominas-Faja","year":"2012","journal-title":"Aging"},{"key":"10.1016\/j.jpba.2014.11.048_bib0125","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.jpba.2012.09.029","volume":"72","author":"Quirantes-Pine","year":"2012","journal-title":"J. Pharm. Biomed."},{"key":"10.1016\/j.jpba.2014.11.048_bib0130","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.foodchem.2012.08.027","volume":"136","author":"Roldan","year":"2013","journal-title":"Food Chem."},{"key":"10.1016\/j.jpba.2014.11.048_bib0135","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1007\/s11306-009-0168-0","volume":"5","author":"Scalbert","year":"2009","journal-title":"Metabolomics"},{"key":"10.1016\/j.jpba.2014.11.048_bib0140","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.jpba.2012.01.033","volume":"63","author":"Fernandez-Arroyo","year":"2012","journal-title":"J. Pharm. Biomed."},{"key":"10.1016\/j.jpba.2014.11.048_bib0145","first-page":"563","volume":"24","author":"Landis-Piwowar","year":"2010","journal-title":"Oncol. Rep."},{"key":"10.1016\/j.jpba.2014.11.048_bib0150","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1124\/dmd.110.037333","volume":"39","author":"Chen","year":"2011","journal-title":"Drug Metab. Dispos."},{"key":"10.1016\/j.jpba.2014.11.048_bib0155","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1038\/nrc839","volume":"2","author":"Vivanco","year":"2002","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.jpba.2014.11.048_bib0160","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.ctrv.2003.07.007","volume":"30","author":"Fresno Vara","year":"2004","journal-title":"Cancer Treat. Rev."},{"key":"10.1016\/j.jpba.2014.11.048_bib0165","doi-asserted-by":"crossref","first-page":"3279","DOI":"10.1038\/sj.onc.1210421","volume":"26","author":"Dhillon","year":"2007","journal-title":"Oncogene"},{"key":"10.1016\/j.jpba.2014.11.048_bib0170","doi-asserted-by":"crossref","first-page":"4136","DOI":"10.1016\/j.fct.2012.08.025","volume":"50","author":"Lee","year":"2012","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.jpba.2014.11.048_bib0175","doi-asserted-by":"crossref","first-page":"2082","DOI":"10.1016\/j.biochi.2013.07.021","volume":"95","author":"Park","year":"2013","journal-title":"Biochimie"},{"key":"10.1016\/j.jpba.2014.11.048_bib0180","first-page":"1525","volume":"21","author":"Androutsopoulos","year":"2009","journal-title":"Oncol. Rep."},{"key":"10.1016\/j.jpba.2014.11.048_bib0185","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1007\/s11010-012-1310-2","volume":"366","author":"Seo","year":"2012","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.jpba.2014.11.048_bib0190","doi-asserted-by":"crossref","first-page":"4479","DOI":"10.1074\/jbc.M305529200","volume":"279","author":"Way","year":"2004","journal-title":"J. Biol. Chem."}],"container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0731708514005925?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0731708514005925?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T08:53:22Z","timestamp":1760000002000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0731708514005925"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2]]},"references-count":38,"alternative-id":["S0731708514005925"],"URL":"https:\/\/doi.org\/10.1016\/j.jpba.2014.11.048","relation":{},"ISSN":["0731-7085"],"issn-type":[{"value":"0731-7085","type":"print"}],"subject":[],"published":{"date-parts":[[2015,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Differential metabolomic analysis of the potential antiproliferative mechanism of olive leaf extract on the JIMT-1 breast cancer cell line","name":"articletitle","label":"Article Title"},{"value":"Journal of Pharmaceutical and Biomedical Analysis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpba.2014.11.048","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}