{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T06:16:15Z","timestamp":1791526575907,"version":"4.3.4"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,8,1]],"date-time":"2015-08-01T00:00:00Z","timestamp":1438387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81220108028"],"award-info":[{"award-number":["81220108028"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["B13038"],"award-info":[{"award-number":["B13038"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Introducing Talents of Discipline to Universities"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"published-print":{"date-parts":[[2015,8]]},"DOI":"10.1016\/j.jpba.2015.03.026","type":"journal-article","created":{"date-parts":[[2015,4,25]],"date-time":"2015-04-25T23:21:02Z","timestamp":1430004062000},"page":"23-35","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":49,"special_numbering":"C","title":["Identification of metabolites of PSORALEAE FRUCTUS in rats by ultra performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry analysis"],"prefix":"10.1016","volume":"112","author":[{"given":"Pei-le","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhi-hong","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng-xiang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiu-yu","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin-sheng","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpba.2015.03.026_bib0150","series-title":"Pharmacopoeia of the People's Republic of China","first-page":"174","author":"The Pharmacopoeia Commission of People's Republic of China","year":"2010"},{"key":"10.1016\/j.jpba.2015.03.026_bib0155","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.fitote.2013.06.016","article-title":"Psoralea corylifolia L. (Buguchi)\u2014Folklore to modern evidence: review","volume":"90","author":"Chopra","year":"2013","journal-title":"Fitoterapia"},{"key":"10.1016\/j.jpba.2015.03.026_bib0160","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0367-326X(99)00151-3","article-title":"Immunomodulatory and antitumour properties of Psoralea corylifolia seeds","volume":"71","author":"Latha","year":"2000","journal-title":"Fitoterapia"},{"key":"10.1016\/j.jpba.2015.03.026_bib0165","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1021\/np970488q","article-title":"DNA polymerase and topoisomerase II inhibitors from Psoralea corylifolia","volume":"61","author":"Sun","year":"1998","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.jpba.2015.03.026_bib0170","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.foodchem.2004.04.029","article-title":"Antioxidants from a Chinese medicinal herb-Psoralea corylifolia L","volume":"91","author":"Guo","year":"2005","journal-title":"Food Chem."},{"key":"10.1016\/j.jpba.2015.03.026_bib0175","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1016\/j.peptides.2006.01.020","article-title":"Psc-AFP, an antifungal protein with trypsin inhibitor activity from Psoralea corylifolia seeds","volume":"27","author":"Yang","year":"2006","journal-title":"Peptides"},{"key":"10.1016\/j.jpba.2015.03.026_bib0180","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1021\/np960157y","article-title":"Antiplatelet flavonoids from seeds of Psoralea corylifolia","volume":"59","author":"Tsai","year":"1996","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.jpba.2015.03.026_bib0185","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.phymed.2009.05.015","article-title":"Phytoestrogens from Psoralea corylifolia reveal estrogen receptor-subtype selectivity","volume":"17","author":"Xin","year":"2010","journal-title":"Phytomedicine"},{"key":"10.1016\/j.jpba.2015.03.026_bib0190","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1055\/s-2001-18343","article-title":"Osteoblastic proliferation stimulating activity of Psoralea corylifolia extracts and two of its flavonoids","volume":"67","author":"Wang","year":"2001","journal-title":"Planta Med."},{"key":"10.1016\/j.jpba.2015.03.026_bib0195","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.jpba.2012.11.001","article-title":"Pre-column derivatization combined with UHPLC\u2013MS\/MS for rapid and sensitive quantification of bakuchiol in rat plasma","volume":"75","author":"Zhuang","year":"2013","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jpba.2015.03.026_bib0200","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/j.jep.2013.11.013","article-title":"A UPLC-MS\/MS method for in vivo and in vitro pharmacokinetic studies of psoralenoside, isopsoralenoside, psoralen and isopsoralen from Psoralea corylifolia extract","volume":"151","author":"Wang","year":"2014","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.jpba.2015.03.026_bib0205","doi-asserted-by":"crossref","first-page":"491","DOI":"10.2174\/1389200211209050491","article-title":"Absorption, disposition, and pharmacokinetics of herbal medicines: what and how?","volume":"13","author":"Li","year":"2012","journal-title":"Curr. Drug Metab."},{"key":"10.1016\/j.jpba.2015.03.026_bib0210","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1124\/dmd.111.038695","article-title":"From single compounds to herbal extract: a strategy to systematically characterize the metabolites of licorice in rats","volume":"39","author":"Xiang","year":"2011","journal-title":"Drug Metab. Dispos."},{"key":"10.1016\/j.jpba.2015.03.026_bib0215","doi-asserted-by":"crossref","first-page":"850","DOI":"10.2174\/138920011797470155","article-title":"Translational research insights into pharmacokinetic herb\u2013drug interactions","volume":"12","author":"Hao","year":"2011","journal-title":"Curr. Drug Metab."},{"key":"10.1016\/j.jpba.2015.03.026_bib0220","doi-asserted-by":"crossref","first-page":"2343","DOI":"10.1002\/rcm.6361","article-title":"Simultaneous characterization of prenylated flavonoids and isoflavonoids in Psoralea corylifolia L. by liquid chromatography with diode-array detection and quadrupole time-of-flight mass spectrometry","volume":"26","author":"Xu","year":"2012","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"10.1016\/j.jpba.2015.03.026_bib0225","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.jpba.2014.03.024","article-title":"Metabolites profile of Xian-Ling-Gu-Bao capsule, a traditional Chinese medicine prescription, in rats by ultra performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry analysis","volume":"96","author":"Geng","year":"2014","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jpba.2015.03.026_bib0230","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1002\/jms.1610","article-title":"Mass defect filter technique and its applications to drug metabolite identification by high-resolution mass spectrometry","volume":"44","author":"Zhang","year":"2009","journal-title":"J. Mass Spectrom."},{"key":"10.1016\/j.jpba.2015.03.026_bib0235","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.jpba.2013.04.029","volume":"83","author":"Liang","year":"2013","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jpba.2015.03.026_bib0240","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.foodchem.2013.02.068","article-title":"Identification of in vitro and in vivo metabolites of isoimperatorin using liquid chromatography\/mass spectrometry","volume":"141","author":"Shi","year":"2013","journal-title":"Food Chem."},{"key":"10.1016\/j.jpba.2015.03.026_bib0245","doi-asserted-by":"crossref","first-page":"2110","DOI":"10.1124\/dmd.110.034553","article-title":"The effects of single nucleotide polymorphisms in CYP2A13 on metabolism of 5-methoxypsoralen","volume":"38","author":"Goto","year":"2010","journal-title":"Drug Metab. Dispos."},{"key":"10.1016\/j.jpba.2015.03.026_bib0250","first-page":"223","article-title":"In vitro biotransformation of xanthohumol, a flavonoid from hops (Humulus lupulus), by rat liver microsomes","volume":"29","author":"Yilmazer","year":"2001","journal-title":"Drug Metab. Dispos."},{"key":"10.1016\/j.jpba.2015.03.026_bib0255","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1002\/mnfr.201100554","article-title":"Pharmacokinetics of xanthohumol and metabolites in rats after oral and intravenous administration","volume":"56","author":"Legette","year":"2012","journal-title":"Mol. Nutr. Food Res."},{"key":"10.1016\/j.jpba.2015.03.026_bib0260","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1365\/s10337-009-1118-8","article-title":"A rapid method for the analysis of ten compounds in Psoralea corylifolia L. by UPLC","volume":"70","author":"Wang","year":"2009","journal-title":"Chromatographia"},{"key":"10.1016\/j.jpba.2015.03.026_bib0265","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1007\/BF02974112","article-title":"Antitumor activity of Psoralea corylifolia","volume":"15","author":"Ryu","year":"1992","journal-title":"Arch. Pharm. Res."},{"key":"10.1016\/j.jpba.2015.03.026_bib0270","doi-asserted-by":"crossref","first-page":"4387","DOI":"10.1016\/j.bmc.2004.06.014","article-title":"Antibacterial prenylflavone derivatives from Psoralea corylifolia and their structure\u2013activity relationship study","volume":"12","author":"Yin","year":"2004","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.jpba.2015.03.026_bib0275","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1021\/np020241f","article-title":"Brosimacutins A-I, nine new flavonoids from Brosimum acutifolium","volume":"65","author":"Takashima","year":"2002","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.jpba.2015.03.026_bib0280","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S0031-9422(98)00621-9","article-title":"Prenylated flavonoids and a dihydro-4-phenylcoumarin from Dorstenia poinsettifolia","volume":"51","author":"Ngadjui","year":"1999","journal-title":"Phytochemistry"},{"key":"10.1016\/j.jpba.2015.03.026_bib0285","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jchromb.2013.09.033","article-title":"Metabolic profile of irisolidone in rats obtained by ultra-high performance liquid chromatography\/quadrupole time-of-flight mass spectrometry","volume":"941","author":"Zhang","year":"2013","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.jpba.2015.03.026_bib0290","first-page":"50","article-title":"Cytotoxic effect and mechanism of bakuchiol and bakuchiol combined with psoralen on HK-2 cell","volume":"24","author":"Jiang","year":"2010","journal-title":"Chin. J. Pharmacol. Toxicol."}],"container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0731708515002034?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0731708515002034?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,23]],"date-time":"2018-09-23T01:51:46Z","timestamp":1537667506000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0731708515002034"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8]]},"references-count":29,"alternative-id":["S0731708515002034"],"URL":"https:\/\/doi.org\/10.1016\/j.jpba.2015.03.026","relation":{},"ISSN":["0731-7085"],"issn-type":[{"value":"0731-7085","type":"print"}],"subject":[],"published":{"date-parts":[[2015,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identification of metabolites of PSORALEAE FRUCTUS in rats by ultra performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry analysis","name":"articletitle","label":"Article Title"},{"value":"Journal of Pharmaceutical and Biomedical Analysis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpba.2015.03.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}