{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T15:54:14Z","timestamp":1780588454002,"version":"3.54.1"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T00:00:00Z","timestamp":1443657600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Jiangsu Specially Appointed Professor Program","award":["Sujiaoshi[2012]27"],"award-info":[{"award-number":["Sujiaoshi[2012]27"]}]},{"name":"China National High Tech R&D program"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"published-print":{"date-parts":[[2015,10]]},"DOI":"10.1016\/j.jpba.2015.06.010","type":"journal-article","created":{"date-parts":[[2015,6,20]],"date-time":"2015-06-20T05:17:01Z","timestamp":1434777421000},"page":"447-454","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":33,"special_numbering":"C","title":["Rapid determination of 1-deoxynojirimycin in Morus alba L. leaves by direct analysis in real time (DART) mass spectrometry"],"prefix":"10.1016","volume":"114","author":[{"given":"Bin","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Yang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ze-Yu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Long","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles C.","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guo-Hua","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpba.2015.06.010_bib0005","doi-asserted-by":"crossref","first-page":"2613","DOI":"10.1021\/jf073223i","article-title":"Antiobesity effects and improvement of insulin sensitivity by 1-dexynojirimycin in animal models","volume":"56","author":"Kong","year":"2008","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.jpba.2015.06.010_bib0010","doi-asserted-by":"crossref","first-page":"155","DOI":"10.7164\/antibiotics.49.155","article-title":"Inhibition of mouse tumor metastasis with nojirimycin-related compounds","volume":"49","author":"Tsuruoka","year":"1996","journal-title":"J. Antibiot."},{"key":"10.1016\/j.jpba.2015.06.010_bib0015","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1006\/viro.1997.8505","article-title":"Recombinant HIV envelope expressed in an alpha-glucosidase I-deficient CHO cell line and its parental cell line in the presence of 1-deoxynojirimycin is functional","volume":"231","author":"Fenouillet","year":"1997","journal-title":"Virology"},{"key":"10.1016\/j.jpba.2015.06.010_bib0020","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1002\/humu.21121","article-title":"The pharmacological chaperone 1-deoxynojirimycin increases the activity and lysosomal trafficking of multiple mutant forms of acid alpha-glucosidase","volume":"30","author":"Flanagan","year":"2009","journal-title":"Hum. Mutat."},{"key":"10.1016\/j.jpba.2015.06.010_bib0025","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.antiviral.2006.03.016","article-title":"Antiviral effects of glycosylation and glucose trimming inhibitors on human parainfluenza virus type 3","volume":"72","author":"Tanaka","year":"2006","journal-title":"Antiviral Res."},{"key":"10.1016\/j.jpba.2015.06.010_bib0030","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.cca.2008.02.014","article-title":"Binding with parameters and thermodynamics of the interaction of imino sugars with a recombinant human acid \u03b1-glucosidase (alglucosidase alfa): insight into the complex formation mechanism","volume":"319","author":"Yoshimizu","year":"2008","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.jpba.2015.06.010_bib0035","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1021\/np970277l","article-title":"Antihyperglycemic effects of N-containing sugars from xan-thoeercis zambesiaca, morusbombycis, aglaonematreubii, and casranospermum austral instreptozotoein-diabetiemiee","volume":"61","author":"Nojima","year":"1998","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.jpba.2015.06.010_bib0040","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0021-9673(03)00728-3","article-title":"Determination of 1-deoxynojirimycin in Morus alba L. leaves by derivatization with 9-fluorenylmethyl chloroformate followed by reversed-phase high-performance liquid chromatography","volume":"1002","author":"Kim","year":"2003","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jpba.2015.06.010_bib0045","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1021\/jf0306901","article-title":"Determination of 1-deoxynojirimycin in mulberry leaves using hydrophilic interaction chromatography with evaporative light scattering detection","volume":"52","author":"Kimura","year":"2004","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.jpba.2015.06.010_bib0050","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1016\/j.jpba.2007.03.031","article-title":"Quantitative determination of 1-deoxynojirimycin in mulberry leaves using liquid chromatography-tandem mass spectrometry","volume":"44","author":"Nuengchamnong","year":"2007","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jpba.2015.06.010_bib0055","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.foodchem.2010.10.097","article-title":"A derivatization procedure for the simultaneous analysis of iminosugars and other low molecular weight carbohydrates by GC\u2013MS in mulberry","volume":"126","author":"Rodr\u00edgue-S\u00e1nchez","year":"2011","journal-title":"Food Chem."},{"key":"10.1016\/j.jpba.2015.06.010_bib0060","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1002\/pca.645","article-title":"Detection of polyhydroxyalkaloids in Lonchocarpus extracts by GC\u2013MS of acetylated derivatives","volume":"13","author":"Magalh\u00e3es","year":"2002","journal-title":"Phytochem. Anal."},{"key":"10.1016\/j.jpba.2015.06.010_bib0065","doi-asserted-by":"crossref","first-page":"4204","DOI":"10.1016\/j.chroma.2010.03.014","article-title":"Rapid determination of melamine and cyanuric acid in milk powder using direct analysis in real time-time-of-flight mass spectrometry","volume":"1217","author":"Vaclavik","year":"2010","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jpba.2015.06.010_bib0070","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1002\/rcm.5316","article-title":"Optimization of direct analysis in real time (DART) linear ion trap parameters for the detection and quantitation of glucose","volume":"26","author":"Saang'onyo","year":"2012","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"10.1016\/j.jpba.2015.06.010_bib0075","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1002\/rcm.6235","article-title":"The evaluation and implementation of direct analysis in real time quadrupole time-of-flight tandem mass spectrometry for characterization and quantification of geniposide in Re Du Ning Injections","volume":"26","author":"Li","year":"2012","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"10.1016\/j.jpba.2015.06.010_bib0080","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.chroma.2014.01.076","article-title":"Rapid quantification of highly polar trimethyl phosphate in wastewater via direct analysis in real-time mass spectrometry","volume":"1333","author":"Wang","year":"2014","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jpba.2015.06.010_bib0085","doi-asserted-by":"crossref","first-page":"7135","DOI":"10.1073\/pnas.0802692105","article-title":"Cuticular hydrocarbon analysis of an awake behaving fly using direct analysis in real-time time-of-flight mass spectrometry","volume":"105","author":"Yew","year":"2008","journal-title":"PNAS"},{"key":"10.1016\/j.jpba.2015.06.010_bib0090","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1111\/j.1556-4029.2008.00955.x","article-title":"Detection of gamma-hydroxybutyric acid in various drink matrices via AccuTOF-DART","volume":"54","author":"Bennett","year":"2009","journal-title":"J. Forensic Sci."},{"key":"10.1016\/j.jpba.2015.06.010_bib0095","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.aca.2014.06.014","article-title":"Rapid identification of traditional Chinese herbal medicine by direct analysis in real time (DART) mass spectrometry","volume":"845","author":"Wang","year":"2014","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.jpba.2015.06.010_bib0100","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.jpba.2013.02.037","article-title":"Direct analysis in real time-mass spectrometry (DART-MS) for rapid qualitative screening of toxic glycols in glycerin-containing products","volume":"80","author":"Self","year":"2013","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jpba.2015.06.010_bib0105","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1021\/ac8022108","article-title":"Observation of molecular ions and analysis of nonpolar compounds with the direct analysis in real time ion source","volume":"81","author":"Cody","year":"2009","journal-title":"Anal. Chem."},{"key":"10.1016\/j.jpba.2015.06.010_bib0110","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.jasms.2008.09.016","article-title":"Ionization mechanism of negative ion-direct analysis in real time: acomparative study with negative ion-atmospheric pressure photoionization","volume":"20","author":"Song","year":"2009","journal-title":"J. Am. Soc. Mass Spectrom."},{"key":"10.1016\/j.jpba.2015.06.010_bib0115","doi-asserted-by":"crossref","first-page":"2589","DOI":"10.1039\/C3AN02193A","article-title":"Ionization characteristics of amino acids in direct analysis in real time mass spectrometry","volume":"10","author":"Sekimoto","year":"2014","journal-title":"Analyst"},{"key":"10.1016\/j.jpba.2015.06.010_bib0120","doi-asserted-by":"crossref","first-page":"2297","DOI":"10.1021\/ac050162j","article-title":"Versatile new ion source for the analysis of materials in open air under ambient conditions","volume":"77","author":"Cody","year":"2005","journal-title":"Anal. Chem."},{"key":"10.1016\/j.jpba.2015.06.010_bib0125","doi-asserted-by":"crossref","first-page":"9834","DOI":"10.1021\/ac901778n","article-title":"Ambient mass spectrometric detection of organometallic compounds using direct analysis in real time","volume":"81","author":"Borges","year":"2009","journal-title":"Anal. Chem."},{"key":"10.1016\/j.jpba.2015.06.010_bib0130","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1021\/ac802117u","article-title":"Simulations and experimental investigation of atmospheric transport in an ambient metastable-induced chemical ionization source","volume":"81","author":"Harris","year":"2009","journal-title":"Anal. Chem."},{"key":"10.1016\/j.jpba.2015.06.010_bib0135","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.aca.2012.04.025","article-title":"Direct analysis in real time mass spectrometry and multivariate data analysis: a novel approach to rapid identification of analytical markers for quality control of traditional Chinese medicine preparation","volume":"733","author":"Zeng","year":"2012","journal-title":"Anal. Chim. Acta"}],"container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0731708515300273?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0731708515300273?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,21]],"date-time":"2018-09-21T12:24:10Z","timestamp":1537532650000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0731708515300273"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10]]},"references-count":27,"alternative-id":["S0731708515300273"],"URL":"https:\/\/doi.org\/10.1016\/j.jpba.2015.06.010","relation":{},"ISSN":["0731-7085"],"issn-type":[{"value":"0731-7085","type":"print"}],"subject":[],"published":{"date-parts":[[2015,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Rapid determination of 1-deoxynojirimycin in Morus alba L. leaves by direct analysis in real time (DART) mass spectrometry","name":"articletitle","label":"Article Title"},{"value":"Journal of Pharmaceutical and Biomedical Analysis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpba.2015.06.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}