{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T13:21:24Z","timestamp":1788441684347,"version":"build-2803163510"},"reference-count":38,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"published-print":{"date-parts":[[2016,1]]},"DOI":"10.1016\/j.jpba.2015.08.020","type":"journal-article","created":{"date-parts":[[2015,8,21]],"date-time":"2015-08-21T02:06:53Z","timestamp":1440122813000},"page":"18-25","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"special_numbering":"C","title":["Manganese modified CdTe\/CdS quantum dots as an immunoassay biosensor for the detection of Golgi protein-73"],"prefix":"10.1016","volume":"117","author":[{"given":"Wei","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aixia","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guanhong","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangdi","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qin","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpba.2015.08.020_bib0005","series-title":"Cancer Facts & Figures 2014","author":"American Cancer Society","year":"2014"},{"key":"10.1016\/j.jpba.2015.08.020_bib0010","first-page":"31","article-title":"Hepatocellular carcinoma in the world and the middle East","volume":"2","author":"Poustchi","year":"2010","journal-title":"Middle East J. Dig. Dis."},{"key":"10.1016\/j.jpba.2015.08.020_bib0015","doi-asserted-by":"publisher","first-page":"570","DOI":"10.1016\/S0168-8278(00)00053-2","article-title":"Serum alpha-fetoprotein for diagnosis of hepatocellular carcinoma in patients with chronic liver disease: influence of HBsAg and anti-HCV status","volume":"34","author":"Trevisani","year":"2001","journal-title":"J. Hepatol."},{"key":"10.1016\/j.jpba.2015.08.020_bib0020","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1111\/j.1572-0241.2006.00467.x","article-title":"Accuracy of ultrasonography, spiral CT, magnetic resonance, and alpha-fetoprotein in diagnosing hepatocellular carcinoma: a systematic review","volume":"101","author":"Colli","year":"2006","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.jpba.2015.08.020_bib0025","doi-asserted-by":"publisher","first-page":"493","DOI":"10.1053\/j.gastro.2009.10.031","article-title":"Des-gamma-carboxy prothrombin and alpha-fetoprotein as biomarkers for the early detection of hepatocellular carcinoma","volume":"138","author":"Lok","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1016\/j.jpba.2015.08.020_bib0030","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1002\/hep.510270140","article-title":"Screening for hepatocellular carcinoma","volume":"27","author":"Collier","year":"1998","journal-title":"Hepatology"},{"key":"10.1016\/j.jpba.2015.08.020_bib0035","first-page":"874","article-title":"GP73 expression and its significance in the diagnosis of hepatocellular carcinoma: a review","volume":"5","author":"Ba","year":"2012","journal-title":"Int. J. Clin. Exp. Pathol."},{"key":"10.1016\/j.jpba.2015.08.020_bib0040","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.1016\/j.jhep.2005.05.028","article-title":"GP73, a resident Golgi glycoprotein, is a novel serum marker for hepatocellular carcinoma","volume":"43","author":"Marrero","year":"2005","journal-title":"J. Hepatol."},{"key":"10.1016\/j.jpba.2015.08.020_bib0045","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1007\/s12032-009-9215-y","article-title":"GP73, a resident Golgi glycoprotein, is sensibility and specificity for hepatocellular carcinoma of diagnosis in a hepatitis B-endemic Asian population","volume":"27","author":"Hu","year":"2010","journal-title":"Med. Oncol."},{"key":"10.1016\/j.jpba.2015.08.020_bib0050","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1258\/acb.2008.008088","article-title":"Quantitative analysis of elevated serum Golgi protein-73 expression in patients with liver diseases","volume":"46","author":"Gu","year":"2009","journal-title":"Ann. Clin. Biochem."},{"key":"10.1016\/j.jpba.2015.08.020_bib0055","doi-asserted-by":"publisher","first-page":"467","DOI":"10.7555\/JBR.26.20120057","article-title":"Generation and characterization of an anti-GP73 monoclonal antibody for immunoblotting and sandwich ELISA","volume":"26","author":"Zhang","year":"2012","journal-title":"J. Biomed. Res."},{"key":"10.1016\/j.jpba.2015.08.020_bib0060","doi-asserted-by":"crossref","first-page":"287","DOI":"10.7785\/tcrt.2012.500205","article-title":"A study of diagnostic value of Golgi protein GP73 and its genetic assay in primary hepatic carcinoma","volume":"10","author":"Shi","year":"2011","journal-title":"Technol. Cancer Res. Treat."},{"key":"10.1016\/j.jpba.2015.08.020_bib0065","doi-asserted-by":"publisher","first-page":"1957","DOI":"10.1074\/mcp.M600176-MCP200","article-title":"Lectin capture strategies combined with mass spectrometry for the discovery of serum glycoprotein biomarkers","volume":"5","author":"Drake","year":"2006","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1016\/j.jpba.2015.08.020_bib0070","doi-asserted-by":"publisher","first-page":"7327","DOI":"10.1021\/la9041887","article-title":"Compact and versatile nickel-nitrilotriacetate-modified quantum dots for protein imaging and forster resonance energy transfer based assay","volume":"26","author":"Park","year":"2010","journal-title":"Langmuir"},{"key":"10.1016\/j.jpba.2015.08.020_bib0075","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1016\/j.elecom.2014.01.021","article-title":"A novel electrochemical immunosensor for Golgi protein 73 assay","volume":"42","author":"Yu","year":"2014","journal-title":"Electrochem. Commun."},{"key":"10.1016\/j.jpba.2015.08.020_bib0080","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.aca.2012.10.060","article-title":"Sandwich-type immunosensors and immunoassays exploiting nanostructure labels: a review","volume":"758","author":"Pei","year":"2013","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.jpba.2015.08.020_bib0085","doi-asserted-by":"publisher","first-page":"9699","DOI":"10.1021\/ac402082s","article-title":"Quantum dot based fluorometric detection of cancer TF-antigen","volume":"85","author":"Li","year":"2013","journal-title":"Anal. Chem."},{"key":"10.1016\/j.jpba.2015.08.020_bib0090","doi-asserted-by":"publisher","first-page":"4578","DOI":"10.1021\/ac400226n","article-title":"Plasma-enhanced antibody immobilization for the development of a capillary-based carcinoembryonic antigen immunosensor using laser-induced fluorescence spectroscopy","volume":"85","author":"Yu","year":"2013","journal-title":"Anal. Chem."},{"key":"10.1016\/j.jpba.2015.08.020_bib0095","doi-asserted-by":"publisher","first-page":"2670","DOI":"10.1039\/b900319c","article-title":"CdTe quantum dot functionalized silica nanosphere labels for ultrasensitive detection of biomarker","volume":"19","author":"Chen","year":"2009","journal-title":"Chem. Commun."},{"key":"10.1016\/j.jpba.2015.08.020_bib0100","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.bios.2014.01.054","article-title":"Aptamer-based microfluidic beads array sensor for simultaneous detection of multiple analytes employing multienzyme-linked nanoparticle amplification and quantum dots labels","volume":"57","author":"Zhang","year":"2014","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.jpba.2015.08.020_bib0105","doi-asserted-by":"publisher","first-page":"6800","DOI":"10.1021\/ac201558w","article-title":"Polymer-functionalized silica nanosphere labels for ultrasensitive detection of tumor necrosis factor-alpha","volume":"83","author":"Yuan","year":"2011","journal-title":"Anal. Chem."},{"key":"10.1016\/j.jpba.2015.08.020_bib0110","doi-asserted-by":"publisher","first-page":"1601","DOI":"10.1039\/C3CS60277J","article-title":"Functional nanoprobes for ultrasensitive detection of biomolecules: an update","volume":"43","author":"Xu","year":"2014","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.jpba.2015.08.020_bib0115","doi-asserted-by":"publisher","first-page":"1283","DOI":"10.1016\/j.bios.2009.10.010","article-title":"High-sensitivity quantum dot-based fluorescence resonance energy transfer bioanalysis by capillary electrophoresis","volume":"25","author":"Li","year":"2010","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.jpba.2015.08.020_bib0120","doi-asserted-by":"publisher","first-page":"307","DOI":"10.1016\/j.talanta.2009.06.061","article-title":"Enhancement of sensitivity and specificity of the fluoroimmunoassay of hepatitis B virus surface antigen through flexible coupling between quantum dots and antibody","volume":"80","author":"Zeng","year":"2009","journal-title":"Talanta"},{"key":"10.1016\/j.jpba.2015.08.020_bib0125","doi-asserted-by":"publisher","first-page":"1438","DOI":"10.1039\/c2ay05794h","article-title":"Manganese modified CdTe\/CdS quantum dots as a highly selective probe to detect trace copper element in beer samples","volume":"4","author":"Wei","year":"2012","journal-title":"Anal. Methods"},{"key":"10.1016\/j.jpba.2015.08.020_bib0130","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1196\/annals.1430.021","article-title":"Stability and fluorescence quantum yield of CdSe-ZnS quantum dots influence of the thickness of the ZnS shell","volume":"1130","author":"Grabolle","year":"2008","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.jpba.2015.08.020_bib0135","doi-asserted-by":"publisher","first-page":"2508","DOI":"10.1021\/ja211224s","article-title":"Mn-doped quantum dot sensitized solar cells: a strategy to boost efficiency over 5%","volume":"134","author":"Santra","year":"2012","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jpba.2015.08.020_bib0140","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1039\/B510888H","article-title":"Simultaneous detection of E. coli O157: H7 and salmonella typhimurium using quantum dots as fluorescence labels","volume":"131","author":"Yang","year":"2006","journal-title":"Analyst"},{"key":"10.1016\/j.jpba.2015.08.020_bib0145","doi-asserted-by":"publisher","first-page":"7804","DOI":"10.1021\/es201333f","article-title":"Bead-based competitive fluorescence immunoassay for sensitive and rapid diagnosis of cyanotoxin risk in drinking water","volume":"45","author":"Yu","year":"2011","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.jpba.2015.08.020_bib0150","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1039\/B918623A","article-title":"Magnetic bead based assay for C-reactive protein using quantum-dot fluorescence labeling and immunoaffinity separation","volume":"135","author":"Zhu","year":"2010","journal-title":"Analyst"},{"key":"10.1016\/j.jpba.2015.08.020_bib0155","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevB.84.195324","article-title":"Orbital pathways for Mn2+-carrier sp-d exchange in diluted magnetic semiconductor quantum dots","volume":"84","author":"Beaulac","year":"2011","journal-title":"Phys. Rev. B"},{"key":"10.1016\/j.jpba.2015.08.020_bib0160","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevB.78.195311","article-title":"Electronic structure of Mn-doped III-V semiconductor quantum dots","volume":"78","author":"Chutia","year":"2008","journal-title":"Phys. Rev. B"},{"key":"10.1016\/j.jpba.2015.08.020_bib0165","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.bios.2012.08.003","article-title":"Homogeneous immunoassays based on fluorescence emission intensity variations of zinc selenide quantum dot sensors","volume":"41","author":"Wang","year":"2013","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.jpba.2015.08.020_bib0170","doi-asserted-by":"publisher","first-page":"15584","DOI":"10.1021\/ja066506k","article-title":"Aptamer-capped nanocrystal quantum dots: a new method for label-free protein detection","volume":"128","author":"Choi","year":"2006","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jpba.2015.08.020_bib0175","doi-asserted-by":"publisher","first-page":"3622","DOI":"10.1016\/j.bios.2009.05.026","article-title":"Nano-bio-chips for high performance multiplexed protein detection: determinations of cancer biomarkers in serum and saliva using quantum dot bioconjugate labels","volume":"24","author":"Jokerst","year":"2009","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.jpba.2015.08.020_bib0180","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1016\/j.snb.2013.05.094","article-title":"Multiplexed immunoassay biosensor for the detection of serum biomarkers -\u03b2-HCG and AFP of down syndrome based on photoluminescent water-soluble CdSe\/ZnS quantum dots","volume":"186","author":"Liu","year":"2013","journal-title":"Senors Actuators B: Chem."},{"key":"10.1016\/j.jpba.2015.08.020_bib0185","doi-asserted-by":"publisher","first-page":"1311","DOI":"10.1515\/CCLM.2011.640","article-title":"Golgi protein 73 (GP73), a useful serum marker in liver diseases","volume":"49","author":"Liu","year":"2011","journal-title":"Clin. Chem. Lab. Med."},{"key":"10.1016\/j.jpba.2015.08.020_bib0190","doi-asserted-by":"publisher","first-page":"12069","DOI":"10.1007\/s13277-014-2506-8","article-title":"Diagnostic value of alpha-fetoprotein-L3 and Golgi protein 73 in hepatocellular carcinomas with low AFP levels","volume":"35","author":"Xu","year":"2014","journal-title":"Tumor Biol."}],"container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0731708515301187?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0731708515301187?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,29]],"date-time":"2019-08-29T17:12:47Z","timestamp":1567098767000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0731708515301187"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,1]]},"references-count":38,"alternative-id":["S0731708515301187"],"URL":"https:\/\/doi.org\/10.1016\/j.jpba.2015.08.020","relation":{},"ISSN":["0731-7085"],"issn-type":[{"value":"0731-7085","type":"print"}],"subject":[],"published":{"date-parts":[[2016,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Manganese modified CdTe\/CdS quantum dots as an immunoassay biosensor for the detection of Golgi protein-73","name":"articletitle","label":"Article Title"},{"value":"Journal of Pharmaceutical and Biomedical Analysis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpba.2015.08.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}