{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T10:37:30Z","timestamp":1778755050967,"version":"3.51.4"},"reference-count":23,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.1016\/j.jpba.2023.115795","type":"journal-article","created":{"date-parts":[[2023,10,13]],"date-time":"2023-10-13T02:26:04Z","timestamp":1697163964000},"page":"115795","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Testing for 2,4-dinitrophenol in human hair by LC-MS\/MS and interpretation issues"],"prefix":"10.1016","volume":"237","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4174-5362","authenticated-orcid":false,"given":"Pascal","family":"Kintz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alice","family":"Ameline","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpba.2023.115795_bib1","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1093\/jat\/31.1.55","article-title":"LC-MS-MS analysis of 2,4-dinitrophenol and its phase I and II metabolites in a case of fatal poisoning","volume":"31","author":"Politi","year":"2007","journal-title":"J. Anal. Toxicol."},{"key":"10.1016\/j.jpba.2023.115795_bib2","first-page":"281","article-title":"Pediatric fatality following ingestion of dinitrophenol: post-mortem identification of a \u201cdietary supplement\u201d","volume":"43","author":"Hsiao","year":"2005","journal-title":"Clin. Toxicol."},{"key":"10.1016\/j.jpba.2023.115795_bib3","first-page":"1363","article-title":"Dinitrophenol \u2013 a dangerous doping agent","volume":"122","author":"Sand","year":"2020","journal-title":"Tidsskr. Nor. Laege"},{"key":"10.1016\/j.jpba.2023.115795_bib4","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1007\/s00204-020-02675-9","article-title":"Diet aid or aid to die: an update on 2,4-dinitrophenol (2,4-DNP) use as a weight-loss product","volume":"94","author":"Sousa","year":"2020","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.jpba.2023.115795_bib5","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s13181-011-0162-6","article-title":"2,4-Dinitrophenol (DNP): a weight-loss agent with significant acute toxicity and risk of death","volume":"7","author":"Grundlingh","year":"2012","journal-title":"J. Med. Toxicol."},{"key":"10.1016\/j.jpba.2023.115795_bib6","first-page":"S51","article-title":"Le 2,4-dinitroph\u00e9nol, un br\u00fbleur de graisse interdit mortellement efficace","volume":"33","author":"Tison","year":"2021","journal-title":"Toxicol. Anal. Clin."},{"key":"10.1016\/j.jpba.2023.115795_bib7","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1111\/1556-4029.14154","article-title":"Analysis of 2,4-dinitrophenol in post-mortem blood and urine by gas chromatography-mass spectrometry: method development and validation and report of three fatalities in the United States","volume":"65","author":"de Campos","year":"2020","journal-title":"J. Forensic Sci."},{"key":"10.1016\/j.jpba.2023.115795_bib8","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1093\/jat\/30.3.219","article-title":"Two deaths attributed to the use of 2,4-dinitrophenol","volume":"30","author":"Miranda","year":"2006","journal-title":"J. Anal. Toxicol."},{"key":"10.1016\/j.jpba.2023.115795_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.jflm.2021.102148","article-title":"2,4-dinitrophenol overdose \u2013 everything old is new again","volume":"79","author":"Griffiths","year":"2021","journal-title":"J. Forensic Leg. Med."},{"key":"10.1016\/j.jpba.2023.115795_bib10","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1007\/s00414-016-1378-4","article-title":"Death within 44 days of 2,4-dinitrophenol intake","volume":"130","author":"Zack","year":"2016","journal-title":"Int. J. Leg. Med."},{"key":"10.1016\/j.jpba.2023.115795_bib11","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1007\/s00414-020-02268-2","article-title":"Death of an apprentice bodybuilder following 2,4-dinitrophenol and clenbuterol intake","volume":"134","author":"Dufayet","year":"2020","journal-title":"Int. J. Leg. Med."},{"key":"10.1016\/j.jpba.2023.115795_bib12","first-page":"5480","article-title":"Hair analysis in forensic toxicology: an updated review with a special focus on pitfalls","volume":"23","author":"Kintz","year":"2017","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.jpba.2023.115795_bib13","first-page":"S119","article-title":"2,4-dinitrophenol (2,4-DNP) poisoning in young athlets: clinical description of chronic exposure and public health perspectives \u2013 around a case report","volume":"34","author":"Hermetet","year":"2022","journal-title":"Toxicol. Anal. Clin."},{"key":"10.1016\/j.jpba.2023.115795_bib14","doi-asserted-by":"crossref","first-page":"g4188","DOI":"10.1136\/bmj.g4188","article-title":"Increase in reports of toxicity from fat burning supplement seen in the UK","volume":"348","author":"Wise","year":"2014","journal-title":"BMJ"},{"key":"10.1016\/j.jpba.2023.115795_bib15","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1111\/1556-4029.13947","article-title":"Segmental hair analysis \u2013 interpretation of the time of drug intake in two patients undergoing drug treatment","volume":"64","author":"Wang","year":"2019","journal-title":"J. Forensic Sci."},{"key":"10.1016\/j.jpba.2023.115795_bib16","article-title":"A different insight in hair analysis: simultaneous measurement of antipsychotic drugs and metabolites in the protein and melanin fraction of hair from criminal justice patients","volume":"312","author":"Del Mar Ramirez Fernandez","year":"2020","journal-title":"Forensic Sci. Int."},{"key":"10.1016\/j.jpba.2023.115795_bib17","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1002\/dta.1674","article-title":"Segmental hair analysis for differentiation of tilidine intake from external contamination using LC-ESI-MS\/MS and MALDI-MS\/MS imaging","volume":"7","author":"Poetzsch","year":"2015","journal-title":"Drug Test. Anal."},{"key":"10.1016\/j.jpba.2023.115795_bib18","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1093\/jat\/bkw052","article-title":"A novel approach to document single exposure to GHB: hair analysis after sweat contamination","volume":"40","author":"Kintz","year":"2016","journal-title":"J. Anal. Toxicol."},{"key":"10.1016\/j.jpba.2023.115795_bib19","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/j.forsciint.2017.10.013","article-title":"High risk of misinterpreting hair analysis results for children tested for methadone","volume":"280","author":"Kintz","year":"2017","journal-title":"Forensic Sci. Int."},{"key":"10.1016\/j.jpba.2023.115795_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.legalmed.2020.101803","article-title":"Specific interpretation of hair concentrations in 2 fatal metformin intoxication cases","volume":"48","author":"Arbouche","year":"2021","journal-title":"Leg. Med."},{"key":"10.1016\/j.jpba.2023.115795_bib21","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.forsciint.2011.01.041","article-title":"Segmental hair analysis can demonstrate external contamination in post-mortem cases","volume":"215","author":"Kintz","year":"2012","journal-title":"Forensic Sci. Int."},{"key":"10.1016\/j.jpba.2023.115795_bib22","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1097\/FTD.0b013e318285d5fa","article-title":"Issues about axial diffusion during segmental hair analysis","volume":"35","author":"Kintz","year":"2013","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.jpba.2023.115795_bib23","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1093\/jat\/bkaa047","article-title":"The difficult interpretation of a hair test result from a 32-month-old child: administration of propranolol and quetiapine or contamination?","volume":"44","author":"Kintz","year":"2020","journal-title":"J. Anal. Toxicol."}],"container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0731708523005642?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0731708523005642?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T09:31:40Z","timestamp":1760002300000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0731708523005642"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":23,"alternative-id":["S0731708523005642"],"URL":"https:\/\/doi.org\/10.1016\/j.jpba.2023.115795","relation":{},"ISSN":["0731-7085"],"issn-type":[{"value":"0731-7085","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Testing for 2,4-dinitrophenol in human hair by LC-MS\/MS and interpretation issues","name":"articletitle","label":"Article Title"},{"value":"Journal of Pharmaceutical and Biomedical Analysis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpba.2023.115795","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"115795"}}