{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T03:59:48Z","timestamp":1792555188625,"version":"4.5.0"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100019065","name":"Tianjin Municipal Science and Technology Program","doi-asserted-by":"publisher","award":["3502Z20224020"],"award-info":[{"award-number":["3502Z20224020"]}],"id":[{"id":"10.13039\/501100019065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017686","name":"Fujian Provincial Health Technology Project","doi-asserted-by":"publisher","award":["2022GGB020"],"award-info":[{"award-number":["2022GGB020"]}],"id":[{"id":"10.13039\/501100017686","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003785","name":"Guangdong Medical Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003785","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2021A1515110114"],"award-info":[{"award-number":["2021A1515110114"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2023A1515011957"],"award-info":[{"award-number":["2023A1515011957"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2022A1515110205"],"award-info":[{"award-number":["2022A1515110205"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2020A1515010979"],"award-info":[{"award-number":["2020A1515010979"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2022A1515110096"],"award-info":[{"award-number":["2022A1515110096"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82002137"],"award-info":[{"award-number":["82002137"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82172283"],"award-info":[{"award-number":["82172283"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.jpba.2024.116023","type":"journal-article","created":{"date-parts":[[2024,2,9]],"date-time":"2024-02-09T00:56:18Z","timestamp":1707440178000},"page":"116023","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Impacts of small-molecule STAT3 inhibitor SC-43 on toxicity, global proteomics and metabolomics of HepG2 cells"],"prefix":"10.1016","volume":"242","author":[{"given":"Ting","family":"Mao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peikun","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhichao","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingying","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinlian","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhijian","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peiyu","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianqiong","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.jpba.2024.116023_bib1","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1001\/jamasurg.2022.7989","article-title":"Management of hepatocellular carcinoma: a review","volume":"158","author":"BROWN","year":"2023","journal-title":"JAMA Surg."},{"issue":"4","key":"10.1016\/j.jpba.2024.116023_bib2","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1038\/s41388-020-01566-8","article-title":"STAT3 phosphorylation at Ser727 and Tyr705 differentially regulates the EMT-MET switch and cancer metastasis","volume":"40","author":"LIN","year":"2021","journal-title":"Oncogene"},{"issue":"41","key":"10.1016\/j.jpba.2024.116023_bib3","doi-asserted-by":"crossref","first-page":"5252","DOI":"10.1038\/onc.2014.445","article-title":"SHP-1 is a negative regulator of epithelial-mesenchymal transition in hepatocellular carcinoma","volume":"34","author":"FAN","year":"2015","journal-title":"Oncogene"},{"issue":"7","key":"10.1016\/j.jpba.2024.116023_bib4","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1038\/nrgastro.2014.10","article-title":"HCC therapies--lessons learned .","volume":"11","author":"W\u00f6RNS","year":"2014","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"issue":"5","key":"10.1016\/j.jpba.2024.116023_bib5","doi-asserted-by":"crossref","first-page":"541","DOI":"10.6004\/jnccn.2021.0022","article-title":"Hepatobiliary cancers, version 2.2021, NCCN clinical practice guidelines in oncology","volume":"19","author":"BENSON","year":"2021","journal-title":"J. Natl. Compr. Canc Netw."},{"issue":"1","key":"10.1016\/j.jpba.2024.116023_bib6","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1002\/hep.26640","article-title":"Discovery of novel Src homology region 2 domain-containing phosphatase 1 agonists from sorafenib for the treatment of hepatocellular carcinoma","volume":"59","author":"TAI","year":"2014","journal-title":"Hepatology"},{"issue":"9","key":"10.1016\/j.jpba.2024.116023_bib7","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1007\/s00109-017-1549-x","article-title":"Sequential combination of docetaxel with a SHP-1 agonist enhanced suppression of p-STAT3 signaling and apoptosis in triple negative breast cancer cells","volume":"95","author":"LIU","year":"2017","journal-title":"J. Mol. Med. (Berl.)"},{"issue":"9","key":"10.1016\/j.jpba.2024.116023_bib8","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.neo.2015.08.007","article-title":"Pharmacological targeting SHP-1-STAT3 signaling is a promising therapeutic approach for the treatment of colorectal cancer","volume":"17","author":"FAN","year":"2015","journal-title":"Neoplasia"},{"issue":"2","key":"10.1016\/j.jpba.2024.116023_bib9","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.canlet.2015.11.039","article-title":"A combination of sorafenib and SC-43 is a synergistic SHP-1 agonist duo to advance hepatocellular carcinoma therapy","volume":"371","author":"CHAO","year":"2016","journal-title":"Cancer Lett."},{"issue":"4","key":"10.1016\/j.jpba.2024.116023_bib10","doi-asserted-by":"crossref","first-page":"R63","DOI":"10.1186\/bcr3457","article-title":"Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells","volume":"15","author":"LIU","year":"2013","journal-title":"Breast Cancer Res."},{"issue":"1","key":"10.1016\/j.jpba.2024.116023_bib11","doi-asserted-by":"crossref","first-page":"1728","DOI":"10.1038\/s41598-017-01572-z","article-title":"Src-homology protein tyrosine phosphatase-1 agonist, SC-43, reduces liver fibrosis","volume":"7","author":"SU","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jpba.2024.116023_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpba.2021.113994","article-title":"Integrated omics and bioinformatics analyses for the toxic mechanism and material basis of Sophorae Tonkinensis radix et rhizome-induced hepatotoxicity","volume":"198","author":"ZHANG","year":"2021","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"9","key":"10.1016\/j.jpba.2024.116023_bib13","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1007\/s00204-006-0091-3","article-title":"High concordance of drug-induced human hepatotoxicity with in vitro cytotoxicity measured in a novel cell-based model using high content screening","volume":"80","author":"O'BRIEN","year":"2006","journal-title":"Arch. Toxicol."},{"issue":"1","key":"10.1016\/j.jpba.2024.116023_bib14","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1093\/toxsci\/kfq026","article-title":"Comparison of HepG2 and HepaRG by whole-genome gene expression analysis for the purpose of chemical hazard identification","volume":"115","author":"JENNEN","year":"2010","journal-title":"Toxicol. Sci."},{"issue":"1","key":"10.1016\/j.jpba.2024.116023_bib15","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1093\/toxsci\/kfq380","article-title":"Proteomics investigations of drug-induced hepatotoxicity in HepG2 cells","volume":"120","author":"VAN SUMMEREN","year":"2011","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.jpba.2024.116023_bib16","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.intimp.2019.04.027","article-title":"Curcumin attenuates collagen-induced rat arthritis via anti-inflammatory and apoptotic effects","volume":"72","author":"WANG","year":"2019","journal-title":"Int. Immunopharmacol."},{"issue":"W1","key":"10.1016\/j.jpba.2024.116023_bib17","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gkac394","article-title":"CB-Dock2: improved protein-ligand blind docking by integrating cavity detection, docking and homologous template fitting","volume":"50","author":"LIU","year":"2022","journal-title":"Nucleic Acids Res."},{"issue":"D1","key":"10.1016\/j.jpba.2024.116023_bib18","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gky1131","article-title":"STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets","volume":"47","author":"SZKLARCZYK","year":"2019","journal-title":"Nucleic Acids Res."},{"issue":"5","key":"10.1016\/j.jpba.2024.116023_bib19","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.3892\/ijmm.2015.2350","article-title":"shRNA-mediated silencing of the RFC3 gene suppresses hepatocellular carcinoma cell proliferation","volume":"36","author":"YAO","year":"2015","journal-title":"Int. J. Mol. Med."},{"issue":"20","key":"10.1016\/j.jpba.2024.116023_bib20","doi-asserted-by":"crossref","first-page":"12008","DOI":"10.1111\/jcmm.15829","article-title":"LMNA functions as an oncogene in hepatocellular carcinoma by regulating the proliferation and migration ability","volume":"24","author":"LIU","year":"2020","journal-title":"J. Cell Mol. Med."},{"key":"10.1016\/j.jpba.2024.116023_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.tice.2022.101954","article-title":"SRRM1 promotes the proliferation, migration, and invasion of hepatocellular carcinoma cells by regulating the JAK\/STAT signaling pathway","volume":"79","author":"SONG","year":"2022","journal-title":"Tissue Cell"},{"issue":"6","key":"10.1016\/j.jpba.2024.116023_bib22","doi-asserted-by":"crossref","first-page":"2342","DOI":"10.1002\/hep.31614","article-title":"Genomic analysis of vascular invasion in HCC reveals molecular drivers and predictive biomarkers","volume":"73","author":"KRISHNAN","year":"2021","journal-title":"Hepatology"},{"issue":"4","key":"10.1016\/j.jpba.2024.116023_bib23","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1002\/9780470559277.ch110180","article-title":"Target identification using drug affinity responsive target stability (DARTS)","volume":"3","author":"LOMENICK","year":"2011","journal-title":"Curr. Protoc. Chem. Biol."},{"issue":"10","key":"10.1016\/j.jpba.2024.116023_bib24","doi-asserted-by":"crossref","first-page":"2783","DOI":"10.1080\/15548627.2020.1841953","article-title":"Antidepressant drug sertraline modulates AMPK-MTOR signaling-mediated autophagy via targeting mitochondrial VDAC1 protein","volume":"17","author":"HWANG","year":"2021","journal-title":"Autophagy"},{"issue":"5","key":"10.1016\/j.jpba.2024.116023_bib25","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1002\/ijc.1391","article-title":"Binding of a SART3 tumor-rejection antigen to a pre-mRNA splicing factor RNPS1: a possible regulation of splicing by a complex formation","volume":"93","author":"HARADA","year":"2001","journal-title":"Int. J. Cancer"},{"issue":"4","key":"10.1016\/j.jpba.2024.116023_bib26","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1002\/hep.24149","article-title":"Comparative analysis of various tumor-associated antigen-specific T-cell responses in patients with hepatocellular carcinoma","volume":"53","author":"MIZUKOSHI","year":"2011","journal-title":"Hepatology"},{"issue":"1","key":"10.1016\/j.jpba.2024.116023_bib27","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0170291","article-title":"Cellular immune responses for squamous cell carcinoma antigen recognized by T Cells 3 in patients with hepatocellular carcinoma","volume":"12","author":"KAJI","year":"2017","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.jpba.2024.116023_bib28","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a026070","article-title":"p53 in the DNA-damage-repair process","volume":"6","author":"WILLIAMS","year":"2016","journal-title":"Cold Spring Harb. Perspect. Med."},{"issue":"16","key":"10.1016\/j.jpba.2024.116023_bib29","doi-asserted-by":"crossref","first-page":"8408","DOI":"10.18632\/aging.204978","article-title":"SART3, regulated by p53, is a biomarker for diagnosis, prognosis and immune infiltration in hepatocellular carcinoma","volume":"15","author":"NONG","year":"2023","journal-title":"Aging (Albany NY)"},{"issue":"6","key":"10.1016\/j.jpba.2024.116023_bib30","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1016\/j.jhep.2019.02.014","article-title":"Clinical practice guidelines: drug-induced liver injury","volume":"70","year":"2019","journal-title":"J. Hepatol."},{"issue":"2","key":"10.1016\/j.jpba.2024.116023_bib31","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1007\/s12072-021-10144-3","article-title":"Drug-induced liver injury: Asia Pacific association of study of liver consensus guidelines","volume":"15","author":"DEVARBHAVI","year":"2021","journal-title":"Hepatol. Int"},{"issue":"3","key":"10.1016\/j.jpba.2024.116023_bib32","doi-asserted-by":"crossref","first-page":"681","DOI":"10.2353\/ajpath.2008.070613","article-title":"Pyrimidine nucleoside depletion sensitizes to the mitochondrial hepatotoxicity of the reverse transcriptase inhibitor stavudine","volume":"172","author":"SETZER","year":"2008","journal-title":"Am. J. Pathol."},{"issue":"Suppl 1","key":"10.1016\/j.jpba.2024.116023_bib33","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1111\/j.1438-8677.2010.00351.x","article-title":"Nucleoside transport and associated metabolism","volume":"12","author":"M\u00f6HLMANN","year":"2010","journal-title":"Plant Biol. (Stuttg.)"},{"issue":"12","key":"10.1016\/j.jpba.2024.116023_bib34","first-page":"722","article-title":"Effect of cytidine and uridine on liver regeneration in rats poisoned by carbon tetrachloride","volume":"88","author":"BUSHMA","year":"1979","journal-title":"Biull Eksp. Biol. Med."},{"issue":"3","key":"10.1016\/j.jpba.2024.116023_bib35","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1038\/s41418-022-00941-0","article-title":"The multifaceted role of ferroptosis in liver disease","volume":"29","author":"CHEN","year":"2022","journal-title":"Cell Death Differ."},{"issue":"14","key":"10.1016\/j.jpba.2024.116023_bib36","doi-asserted-by":"crossref","first-page":"2401","DOI":"10.1016\/j.cell.2022.06.003","article-title":"Ferroptosis turns 10: emerging mechanisms, physiological functions, and therapeutic applications","volume":"185","author":"STOCKWELL","year":"2022","journal-title":"Cell"},{"issue":"15","key":"10.1016\/j.jpba.2024.116023_bib37","doi-asserted-by":"crossref","first-page":"4383","DOI":"10.1158\/0008-5472.CAN-15-2926","article-title":"MSH2 dysregulation is triggered by proinflammatory cytokine stimulation and is associated with liver cancer development","volume":"76","author":"ESO","year":"2016","journal-title":"Cancer Res."},{"issue":"3","key":"10.1016\/j.jpba.2024.116023_bib38","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/j.bbrc.2018.02.167","article-title":"Oncogene RPA1 promotes proliferation of hepatocellular carcinoma via CDK4\/Cyclin-D pathway","volume":"498","author":"WANG","year":"2018","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"20","key":"10.1016\/j.jpba.2024.116023_bib39","doi-asserted-by":"crossref","DOI":"10.3390\/ijms232012213","article-title":"Aluminum, arsenic, beryllium, cadmium, chromium, cobalt, copper, iron, lead, mercury, molybdenum, nickel, platinum, thallium, titanium, vanadium, and zinc: molecular aspects in experimental liver injury","volume":"23","author":"TESCHKE","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.jpba.2024.116023_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2023.102749","article-title":"Glycerol as a precursor for hepatic de novo glutathione synthesis in human liver","volume":"63","author":"JIN","year":"2023","journal-title":"Redox Biol."},{"issue":"7","key":"10.1016\/j.jpba.2024.116023_bib41","doi-asserted-by":"crossref","first-page":"4298","DOI":"10.1111\/jcmm.15090","article-title":"Hedgehog signalling mediates drug resistance through targeting TAP1 in hepatocellular carcinoma","volume":"24","author":"ZHOU","year":"2020","journal-title":"J. Cell Mol. Med."},{"issue":"8","key":"10.1016\/j.jpba.2024.116023_bib42","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1111\/jgh.12186","article-title":"Antigen peptide transporter 1 is involved in the development of fructose-induced hepatic steatosis in mice","volume":"28","author":"ARINDKAR","year":"2013","journal-title":"J. Gastroenterol. Hepatol."},{"issue":"9","key":"10.1016\/j.jpba.2024.116023_bib43","doi-asserted-by":"crossref","first-page":"4560","DOI":"10.1093\/nar\/gky220","article-title":"RNA-splicing factor SART3 regulates translesion DNA synthesis","volume":"46","author":"HUANG","year":"2018","journal-title":"Nucleic Acids Res."},{"issue":"21","key":"10.1016\/j.jpba.2024.116023_bib44","doi-asserted-by":"crossref","first-page":"5643","DOI":"10.1182\/blood-2010-12-325332","article-title":"TIP110\/p110nrb\/SART3\/p110 regulation of hematopoiesis through CMYC","volume":"117","author":"LIU","year":"2011","journal-title":"Blood"}],"container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0731708524000633?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0731708524000633?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T18:06:51Z","timestamp":1777572411000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0731708524000633"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":44,"alternative-id":["S0731708524000633"],"URL":"https:\/\/doi.org\/10.1016\/j.jpba.2024.116023","relation":{},"ISSN":["0731-7085"],"issn-type":[{"value":"0731-7085","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impacts of small-molecule STAT3 inhibitor SC-43 on toxicity, global proteomics and metabolomics of HepG2 cells","name":"articletitle","label":"Article Title"},{"value":"Journal of Pharmaceutical and Biomedical Analysis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpba.2024.116023","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"116023"}}