{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,3]],"date-time":"2025-12-03T20:40:38Z","timestamp":1764794438232},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.jpba.2024.116271","type":"journal-article","created":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T05:53:09Z","timestamp":1717393989000},"page":"116271","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Comparison of whole-blood sirolimus concentrations measured by EMIT-based Siemens Viva-ProE\u00ae System and LC-MS\/MS in Chinese transplant patients"],"prefix":"10.1016","volume":"247","author":[{"given":"Rongqi","family":"Lin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yipeng","family":"Cai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yingbin","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xueyong","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yiying","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bo","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaixian","family":"Lai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junnan","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maobai","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yisheng","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongqiang","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpba.2024.116271_bib1","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1002\/phar.2716","article-title":"Consensus recommendations for use of maintenance immunosuppression in solid organ transplantation: endorsed by the American College of Clinical Pharmacy, American Society of Transplantation, and the International Society for Heart and Lung Transplantation","volume":"42","author":"Nelson","year":"2022","journal-title":"Pharmacother. J. Hum. Pharm. Drug Ther."},{"key":"10.1016\/j.jpba.2024.116271_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpba.2021.114315","article-title":"Overview of therapeutic drug monitoring of immunosuppressive drugs: analytical and clinical practices","volume":"205","author":"Seyfinejad","year":"2021","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jpba.2024.116271_bib3","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1097\/TP.0b013e3181a059a1","article-title":"Sirolimus in Kidney Transplantation indications and practical guidelines: de novo sirolimus-based therapy without calcineurin inhibitors","volume":"87","author":"Flechner","year":"2009","journal-title":"Transplant"},{"key":"10.1016\/j.jpba.2024.116271_bib4","first-page":"765","article-title":"Chinese expert consensus on clinical application of inhibitors of mammalian target of rapamycin in liver transplant recipients (2023 edition)","volume":"14","author":"Huo","year":"2023","journal-title":"Organ Transpl."},{"key":"10.1016\/j.jpba.2024.116271_bib5","first-page":"801","article-title":"Consensus of medical experts on long-term management of immunosuppressive agents in renal transplant patients","volume":"32","author":"Liu","year":"2022","journal-title":"Pharm. Today"},{"key":"10.1016\/j.jpba.2024.116271_bib6","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1016\/j.healun.2020.06.024","article-title":"Report from the 2018 consensus conference on immunomodulating agents in thoracic transplantation: access, formulations, generics, therapeutic drug monitoring, and special populations","volume":"39","author":"Cochrane","year":"2020","journal-title":"J. Heart Lung Transplant."},{"key":"10.1016\/j.jpba.2024.116271_bib7","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1097\/FTD.0000000000000205","article-title":"Impact of laboratory practices on interlaboratory variability in therapeutic drug monitoring of immunosuppressive drugs","volume":"37","author":"Christians","year":"2015","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.jpba.2024.116271_bib8","first-page":"1699","article-title":"A survey on the implementation of therapeutic drug monitoring projects in medical and related institutions across China","volume":"41","author":"Liu","year":"2022","journal-title":"Her. Med."},{"key":"10.1016\/j.jpba.2024.116271_bib9","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.jpba.2013.08.001","article-title":"Liquid chromatography-tandem mass spectrometry method as the golden standard for therapeutic drug monitoring in renal transplant","volume":"86","author":"Aucella","year":"2013","journal-title":"J. Pharm. Biomed. Anal."},{"key":"10.1016\/j.jpba.2024.116271_bib10","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1016\/j.clinbiochem.2008.02.015","article-title":"Quantification of cyclosporine and tacrolimus in whole blood. Comparison of liquid chromatography\u2013electrospray mass spectrometry with the enzyme multiplied immunoassay technique","volume":"41","author":"Ansermot","year":"2008","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.jpba.2024.116271_bib11","doi-asserted-by":"crossref","unstructured":"Y.T. Zhao, H.R. Dai, Y. Li, Y.Y. Zhang, H.L. Guo, X.S. Ding, Y.H. Hu, F. Chen, Comparison of LC-MS\/MS and EMIT methods for the precise determination of blood sirolimus in children with vascular anomalies, Front. Pharm., vol. 13, 925018.","DOI":"10.3389\/fphar.2022.925018"},{"key":"10.1016\/j.jpba.2024.116271_bib12","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1097\/FTD.0000000000000252","article-title":"Evaluation of the waters masstrak LC\u2013MS\/MS assay for tacrolimus and a comparison to the Abbott Architect immunoassay","volume":"38","author":"Saitman","year":"2016","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.jpba.2024.116271_bib13","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.cca.2020.05.007","article-title":"Comparison of LC-MS\/MS and chemiluminescent immunoassays for immunosuppressive drugs reveals organ dependent variation in blood cyclosporine a concentrations","volume":"508","author":"Becker","year":"2020","journal-title":"Clin. Chim. Acta"},{"key":"10.1016\/j.jpba.2024.116271_bib14","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1093\/ajcp\/aqad114","article-title":"Is the automated Elecsys tacrolimus assay on the Roche cobase 602 analyzer an acceptable replacement for a liquid chromatography\u2013tandem mass spectrometry\u2013based assay?","volume":"161","author":"Kanegusuku","year":"2024","journal-title":"Am. J. Clin. Pathol."},{"key":"10.1016\/j.jpba.2024.116271_bib15","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.clinbiochem.2010.10.005","article-title":"Comparison of blood sirolimus, tacrolimus and everolimus concentrations measured by LC-MS\/MS, HPLC-UV and immunoassay methods","volume":"44","author":"Sallustio","year":"2011","journal-title":"Clin. Biochem."},{"key":"10.1016\/j.jpba.2024.116271_bib16","unstructured":"Siemens Healthineers, Viva-ProE System, 2024. \u3008https:\/\/www.siemens-healthineers.com\/en-sg\/drug-testing-diagnostics\/viva-drug-testing\/viva-pro-e-system\u3009, (Accessed 20 January 2024)."},{"key":"10.1016\/j.jpba.2024.116271_bib17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1208\/aapsj060428","article-title":"Exposure-response relationships and drug interactions of sirolimus","volume":"6","author":"Zimmerman","year":"2004","journal-title":"AAPS J."},{"key":"10.1016\/j.jpba.2024.116271_bib18","first-page":"674","article-title":"Current status and standardization conception of the testing quality of therapeutic drug monitoring samples","volume":"44","author":"Guo","year":"2021","journal-title":"Chin. J. Lab. Med."},{"key":"10.1016\/j.jpba.2024.116271_bib19","doi-asserted-by":"crossref","unstructured":"K. Shigeta, M. Kikuchi, M. Tanaka, S. Takasaki, H. Oishi, T. Sado, Y. Matsuda, M. Noda, Y. Okada, N. Mano, H. Yamaguchi, Development of a precise quantitative method for monitoring sirolimus in whole blood using LC\/ESI-MS\/MS, Biomed. Chromatogr., vol. 34, e4853.","DOI":"10.1002\/bmc.4853"},{"key":"10.1016\/j.jpba.2024.116271_bib20","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1080\/00031305.1990.10475751","article-title":"A suggestion for using powerful and informative tests of normality","volume":"44","author":"D\u2019agostino","year":"1990","journal-title":"Am. Stat."},{"key":"10.1016\/j.jpba.2024.116271_bib21","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1093\/clinchem\/46.1.100","article-title":"General Deming regression for estimating systematic bias and its confidence interval in method-comparison studies","volume":"46","author":"Martin","year":"2000","journal-title":"Clin. Chem."},{"key":"10.1016\/j.jpba.2024.116271_bib22","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0140-6736(86)90837-8","article-title":"Statistical methods for assessing agreement between two methods of clinical measurement","volume":"1","author":"Bland","year":"1986","journal-title":"Lancet"},{"key":"10.1016\/j.jpba.2024.116271_bib23","series-title":"Wiley StatsRef: Statistics Reference Online","author":"Ruggeri","year":"2014"},{"key":"10.1016\/j.jpba.2024.116271_bib24","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1080\/00365513.2020.1868048","article-title":"Correlation between enzyme multiplied immunoassay technique and high-performance liquid chromatography in the quantification of voriconazole in a paediatric population","volume":"81","author":"Li","year":"2021","journal-title":"Scand. J. Clin. Lab. Invest."},{"key":"10.1016\/j.jpba.2024.116271_bib25","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1097\/01.ftd.0000199360.25755.20","article-title":"Comparison of the reintroduced MEIA assay with HPLC-MS\/MS for the determination of whole-blood sirolimus from transplant recipients","volume":"28","author":"Morris","year":"2006","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.jpba.2024.116271_bib26","doi-asserted-by":"crossref","unstructured":"Y. Xia, J.Y. Long, M.Y. Shen, N. Dong, H.L. Guo, Y.H. Hu, X.P. Lu, X.S. Ding, F. Chen, J.C. Qiu, Switching between LC-ESI-MS\/MS and EMIT methods for routine TDM of valproic acid in pediatric patients with epilepsy: what clinicians and researchers need to know, Front. Pharm., vol. 12, 750744.","DOI":"10.3389\/fphar.2021.750744"},{"key":"10.1016\/j.jpba.2024.116271_bib27","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1097\/01.ftd.0000197092.84935.ef","article-title":"Determination of mycophenolic acid plasma levels in renal transplant recipients co-administered sirolimus: comparison of an enzyme multiplied immunoassay technique (EMIT) and liquid chromatography-tandem mass spectrometry","volume":"28","author":"Pr\u00e9maud","year":"2006","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.jpba.2024.116271_bib28","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1111\/j.1399-3046.2008.00956.x","article-title":"Characterization of sirolimus metabolites in pediatric solid organ transplant recipients","volume":"13","author":"Filler","year":"2009","journal-title":"Pediatr. Transplant."},{"key":"10.1016\/j.jpba.2024.116271_bib29","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1097\/FTD.0b013e31816ba73a","article-title":"Pharmacokinetics of mycophenolate mofetil and sirolimus in children","volume":"30","author":"Filler","year":"2008","journal-title":"Ther. Drug Monit."},{"key":"10.1016\/j.jpba.2024.116271_bib30","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1515\/CCLM.2006.080","article-title":"Evaluation of an immunoassay of whole blood sirolimus in pediatric transplant patients in comparison with high-performance liquid chromatography\/tandem mass spectrometry","volume":"44","author":"Vicente","year":"2006","journal-title":"Clin. Chem. Lab. Med."},{"key":"10.1016\/j.jpba.2024.116271_bib31","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1097\/01.tp.0000331663.71507.7e","article-title":"The EMIT\u00ae 2000 sirolimus assay* on the V-TWIN\u00ae\/VIVA E\u00ae analyzers","volume":"86","author":"Ryzewski","year":"2008","journal-title":"Transplant"},{"key":"10.1016\/j.jpba.2024.116271_bib32","doi-asserted-by":"crossref","first-page":"3223","DOI":"10.1016\/j.transproceed.2004.12.005","article-title":"The relative proportions of sirolimus metabolites in blood using HPLC with mass-spectrometric detection","volume":"36","author":"Holt","year":"2004","journal-title":"Transplant. Proc."}],"container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073170852400311X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073170852400311X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,7,10]],"date-time":"2024-07-10T06:39:01Z","timestamp":1720593541000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S073170852400311X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":32,"alternative-id":["S073170852400311X"],"URL":"https:\/\/doi.org\/10.1016\/j.jpba.2024.116271","relation":{},"ISSN":["0731-7085"],"issn-type":[{"value":"0731-7085","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparison of whole-blood sirolimus concentrations measured by EMIT-based Siemens Viva-ProE\u00ae System and LC-MS\/MS in Chinese transplant patients","name":"articletitle","label":"Article Title"},{"value":"Journal of Pharmaceutical and Biomedical Analysis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpba.2024.116271","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"116271"}}