{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T18:59:51Z","timestamp":1786993191593,"version":"build-2736575974"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.jpba.2024.116272","type":"journal-article","created":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T12:03:38Z","timestamp":1717416218000},"page":"116272","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Estimation of the time of zolpidem intake and differentiation between consumption and external contamination using MALDI-MSI for investigations on single hair samples"],"prefix":"10.1016","volume":"248","author":[{"given":"Jiao-Jiao","family":"Ji","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaman","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiran","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duoqi","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Xiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junling","family":"Dun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.jpba.2024.116272_bib1","doi-asserted-by":"crossref","first-page":"e16","DOI":"10.1093\/jat\/bkaa174","article-title":"Long-Term Detection in Hair of Zolpidem, Oxazepam and flunitrazepam in a case of drug-facilitated sexual assault","volume":"46","author":"Carfora","year":"2022","journal-title":"J. Anal. Toxicol."},{"issue":"4","key":"10.1016\/j.jpba.2024.116272_bib2","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1093\/jat\/25.4.221","article-title":"Amphetamine and N-acetylamphetamine incorporation into hair: an investigation of the potential role of drug basicity in hair color bias","volume":"25","author":"Borges","year":"2001","journal-title":"J. Anal. Toxicol."},{"issue":"1-3","key":"10.1016\/j.jpba.2024.116272_bib3","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0379-0738(96)02060-9","article-title":"analysis for Drug Abuse XV. Disposition of 3,4-methylenedioxymethamphetamine (MDMA) and its related compounds into rat hair and application to hair analysis for MDMA abuse","volume":"84","author":"Ruri","year":"1997","journal-title":"Forensic Sci. Int."},{"issue":"116","key":"10.1016\/j.jpba.2024.116272_bib4","first-page":"30","article-title":"Studies on mechanism of drug incorporation into hair","volume":"116","author":"Kikura","year":"1998","journal-title":"Bull. Natl. Inst. Health Sci."},{"key":"10.1016\/j.jpba.2024.116272_bib5","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.forsciint.2018.01.028","article-title":"Hair analysis when external contamination is in question: A review of practical approach for the interpretation of results","volume":"285","author":"Tsanaclis","year":"2018","journal-title":"Forensic Sci. Int."},{"key":"10.1016\/j.jpba.2024.116272_bib6","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.forsciint.2018.04.027","article-title":"Micro-segmental hair analysis for proving drug-facilitated crimes: Evidence that a victim ingested a sleeping aid, diphenhydramine, on a specific day","volume":"288","author":"Kuwayama","year":"2018","journal-title":"Forensic Sci. Int."},{"issue":"7","key":"10.1016\/j.jpba.2024.116272_bib7","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1002\/dta.3025","article-title":"Development of an improved method to estimate the days of continuous drug ingestion, based on the micro-segmental hair analysis","volume":"13","author":"Kuwayama","year":"2021","journal-title":"Drug. Test. Anal."},{"key":"10.1016\/j.jpba.2024.116272_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.forsciint.2020.110643","article-title":"Application of MALDI MS imaging after sequential processing of latent fingermarks","volume":"319","author":"Bradshaw","year":"2021","journal-title":"Forensic Sci. Int."},{"issue":"14","key":"10.1016\/j.jpba.2024.116272_bib9","doi-asserted-by":"crossref","first-page":"5585","DOI":"10.1021\/ac200619f","article-title":"Two-step matrix application for the enhancement and imaging of latent fingermarks","volume":"83","author":"Ferguson","year":"2011","journal-title":"Anal. Chem."},{"issue":"12","key":"10.1016\/j.jpba.2024.116272_bib10","doi-asserted-by":"crossref","first-page":"4080","DOI":"10.1039\/D1AN00474C","article-title":"A general purpose MALDI matrix for the analyses of small organic, peptide and protein molecules","volume":"146","author":"Gu","year":"2021","journal-title":"Analyst"},{"issue":"4","key":"10.1016\/j.jpba.2024.116272_bib11","doi-asserted-by":"crossref","DOI":"10.1002\/wfs2.1403","article-title":"The forensic exploitation of fingermark chemistry: a review","volume":"3","author":"Bleay","year":"2021","journal-title":"WIREs Forensic Sci."},{"issue":"1","key":"10.1016\/j.jpba.2024.116272_bib12","doi-asserted-by":"crossref","DOI":"10.1038\/srep11716","article-title":"Detection and mapping of illicit drugs and their metabolites in fingermarks by MALDI MS and compatibility with forensic techniques","volume":"5","author":"Groeneveld","year":"2015","journal-title":"Sci. Rep."},{"issue":"8","key":"10.1016\/j.jpba.2024.116272_bib13","doi-asserted-by":"crossref","first-page":"5821","DOI":"10.1021\/acs.analchem.9b05401","article-title":"High spatial-resolution matrix-assisted laser desorption\/ionization-ion trap-time-of-flight tandem mass spectrometry imaging for depicting longitudinal and transverse distribution of drugs incorporated into hair","volume":"92","author":"Kamata","year":"2020","journal-title":"Anal. Chem."},{"issue":"1","key":"10.1016\/j.jpba.2024.116272_bib14","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1002\/jms.1463","article-title":"A fast screening MALDI method for the detection of cocaine and its metabolites in hair","volume":"44","author":"Vogliardi","year":"2009","journal-title":"J. Mass. Spectrom.: J. Mass. Spectrom."},{"key":"10.1016\/j.jpba.2024.116272_bib15","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.jpba.2017.04.015","article-title":"Matrix-assisted laser-desorption\/ionization mass spectrometric imaging of olanzapine in a single hair using esculetin as a matrix","volume":"141","author":"Wang","year":"2017","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"23","key":"10.1016\/j.jpba.2024.116272_bib16","doi-asserted-by":"crossref","first-page":"11758","DOI":"10.1021\/ac503193w","article-title":"Single hair analysis of small molecules using MALDI-triple quadrupole MS imaging and LC-MS\/MS: investigations on opportunities and pitfalls","volume":"86","author":"Poetzsch","year":"2014","journal-title":"Anal. Chem."},{"issue":"2","key":"10.1016\/j.jpba.2024.116272_bib17","first-page":"151","article-title":"Analysis of Forty-Two Psychoactive Substances in a Single Hair by Micro-Segmental Technique","volume":"39","author":"Ji","year":"2023","journal-title":"Fa yi xue za zhi"},{"key":"10.1016\/j.jpba.2024.116272_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpba.2020.113459","article-title":"Internal quality control samples for hair testing","volume":"188","author":"Nielsen","year":"2020","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"17","key":"10.1016\/j.jpba.2024.116272_bib19","doi-asserted-by":"crossref","first-page":"4015","DOI":"10.1007\/s00216-018-1014-x","article-title":"MALDI matrices for low molecular weight compounds: an endless story","volume":"410","author":"Calvano","year":"2018","journal-title":"Anal. Bioanal. Chem."},{"issue":"8","key":"10.1016\/j.jpba.2024.116272_bib20","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1002\/asia.202100044","article-title":"MALDI matrices for the analysis of low molecular weight compounds: rational design, challenges and perspectives","volume":"16","author":"Qiao","year":"2021","journal-title":"Chem. Asian J."},{"issue":"5","key":"10.1016\/j.jpba.2024.116272_bib21","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1007\/s00216-007-1491-9","article-title":"Laser-induced Fourier transform ion cyclotron resonance mass spectrometry of organic and inorganic compounds: methodologies and applications","volume":"389","author":"Aubriet","year":"2007","journal-title":"Anal. Bioanal. Chem."},{"issue":"Suppl 1","key":"10.1016\/j.jpba.2024.116272_bib22","article-title":"Toward understanding the ionization mechanism of matrix-assisted ionization using mass spectrometry experiment and theory","volume":"35","author":"Lee","year":"2021","journal-title":"Rapid\u00a0Commun. Mass. Spectrom."},{"issue":"10","key":"10.1016\/j.jpba.2024.116272_bib23","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1002\/dta.1812","article-title":"Preparation of longitudinal sections of hair samples for the analysis of cocaine by MALDI-MS\/MS and TOF-SIMS imaging","volume":"7","author":"Flinders","year":"2015","journal-title":"Drug. Test. Anal."},{"issue":"19","key":"10.1016\/j.jpba.2024.116272_bib24","doi-asserted-by":"crossref","first-page":"4611","DOI":"10.1007\/s00216-014-7898-1","article-title":"Mass imaging of ketamine in a single scalp hair by MALDI-FTMS","volume":"406","author":"Shen","year":"2014","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.jpba.2024.116272_bib25","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.aca.2017.04.012","article-title":"Matrix-assisted laser desorption\/ionization mass spectrometric imaging for the rapid segmental analysis of methamphetamine in a single hair using umbelliferone as a matrix","volume":"975","author":"Wang","year":"2017","journal-title":"Anal. Chim. Acta"},{"issue":"2","key":"10.1016\/j.jpba.2024.116272_bib26","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s11419-011-0109-2","article-title":"Imaging of methamphetamine incorporated into hair by MALDI-TOF mass spectrometry","volume":"29","author":"Miki","year":"2011","journal-title":"Forensic Toxicol."},{"key":"10.1016\/j.jpba.2024.116272_bib27","doi-asserted-by":"crossref","first-page":"2805","DOI":"10.1038\/srep02805","article-title":"In situ label-free imaging for visualizing the biotransformation of a bioactive polyphenol","volume":"3","author":"Kim","year":"2013","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.jpba.2024.116272_bib28","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s11419-022-00619-9","article-title":"Micro-segmental hair analysis: detailed procedures and applications in forensic toxicology","volume":"40","author":"Kuwayama","year":"2022","journal-title":"Forensic Toxicol."},{"issue":"3","key":"10.1016\/j.jpba.2024.116272_bib29","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1124\/dmd.116.074211","article-title":"Incorporation of zolpidem into hair and its distribution after a single administration","volume":"45","author":"Shima","year":"2017","journal-title":"Drug. Metab. Dispos."},{"issue":"1-3","key":"10.1016\/j.jpba.2024.116272_bib30","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/0379-0738(93)90256-A","article-title":"Mechanisms of drug incorporation into hair","volume":"63","author":"Henderson","year":"1993","journal-title":"Forensic Sci. Int."},{"issue":"9","key":"10.1016\/j.jpba.2024.116272_bib31","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1093\/jat\/bkaa151","article-title":"The distribution of quetiapine and 7-hydroxyquetiapine in guinea pig hair roots and shafts after repeated administration: exploration of the mechanism of drug entry and retention in hair","volume":"45","author":"Ji","year":"2021","journal-title":"J. Anal. Toxicol."},{"issue":"1","key":"10.1016\/j.jpba.2024.116272_bib32","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1520\/JFS13907J","article-title":"On pathways for small molecules into and out of human hair fibers","volume":"41","author":"P\u00f6tsch","year":"1996","journal-title":"J. Forensic Sci."},{"issue":"1-3","key":"10.1016\/j.jpba.2024.116272_bib33","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0379-0738(99)00153-X","article-title":"The incorporation of dyes into hair as a model for drug binding","volume":"107","author":"DeLauder","year":"2000","journal-title":"Forensic Sci. Int."},{"key":"10.1016\/j.jpba.2024.116272_bib34","first-page":"1","article-title":"Recent trends in analytical methods and separation techniques for drugs of abuse in hair","volume":"856","author":"Baciu","year":"2015","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.jpba.2024.116272_bib35","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.forsciint.2015.07.023","article-title":"Ethnic hair care products may increase false positives in hair drug testing","volume":"257","author":"Kidwell","year":"2015","journal-title":"Forensic Sci. Int."}],"container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0731708524003121?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0731708524003121?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,20]],"date-time":"2024-09-20T23:44:16Z","timestamp":1726875856000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0731708524003121"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":35,"alternative-id":["S0731708524003121"],"URL":"https:\/\/doi.org\/10.1016\/j.jpba.2024.116272","relation":{},"ISSN":["0731-7085"],"issn-type":[{"value":"0731-7085","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Estimation of the time of zolpidem intake and differentiation between consumption and external contamination using MALDI-MSI for investigations on single hair samples","name":"articletitle","label":"Article Title"},{"value":"Journal of Pharmaceutical and Biomedical Analysis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpba.2024.116272","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"116272"}}