{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T12:12:22Z","timestamp":1791547942909,"version":"4.3.4"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFC3503805"],"award-info":[{"award-number":["2023YFC3503805"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010029","name":"Taishan Scholar Foundation of Shandong Province","doi-asserted-by":"publisher","award":["tsqn202306252"],"award-info":[{"award-number":["tsqn202306252"]}],"id":[{"id":"10.13039\/501100010029","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010040","name":"Taishan Scholar Project of Shandong Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010040","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1016\/j.jpba.2025.116845","type":"journal-article","created":{"date-parts":[[2025,4,4]],"date-time":"2025-04-04T07:11:58Z","timestamp":1743750718000},"page":"116845","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Macroporous covalent organic framework for efficient online solid-phase extraction of aflatoxins from traditional Chinese medicines"],"prefix":"10.1016","volume":"262","author":[{"given":"Wenhua","family":"Ji","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaojun","family":"Zong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heng","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuemei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaomei","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenfang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongyu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jpba.2025.116845_bib1","doi-asserted-by":"crossref","first-page":"46","DOI":"10.3390\/toxins13010046","article-title":"Aflatoxin detoxification using microorganisms and enzymes","volume":"13","author":"Guan","year":"2021","journal-title":"Toxins"},{"key":"10.1016\/j.jpba.2025.116845_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2024.125915","article-title":"A magnetic graphene oxide and UiO-66 based homogeneous dual recognition electrochemical aptasensor for accurate and sensitive detection of aflatoxin B1","volume":"273","author":"Yao","year":"2024","journal-title":"Talanta"},{"key":"10.1016\/j.jpba.2025.116845_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2024.137162","article-title":"Effective magnetic nanoadsorbent based on natural carboxymethyl cellulose\/polyaniline nanotube\/graphene oxide for aflatoxin B1 and B2 adsorption in rice utilizing a novel synthesis method","volume":"282","author":"Karami-Osboo","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.jpba.2025.116845_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2020.105206","article-title":"Rapid and sensitive extraction of aflatoxins by Fe3O4\/zeolite nanocomposite adsorbent in rice samples","volume":"158","author":"Karami-Osboo","year":"2020","journal-title":"Microchem. J."},{"key":"10.1016\/j.jpba.2025.116845_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2023.137342","article-title":"Molecularly imprinted dispersive micro solid-phase extraction coupled with high-performance liquid chromatography for the determination of four aflatoxins in various foods","volume":"433","author":"Thati","year":"2024","journal-title":"Food Chem."},{"key":"10.1016\/j.jpba.2025.116845_bib6","doi-asserted-by":"crossref","first-page":"5230","DOI":"10.1021\/acs.jafc.9b01044","article-title":"A rapid and nondestructive method for simultaneous determination of aflatoxigenic fungus and aflatoxin contamination on corn kernels","volume":"67","author":"Tao","year":"2019","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.jpba.2025.116845_bib7","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1007\/BF02945093","article-title":"Fungal and aflatoxin contamination of medicinal herbs","volume":"14","author":"Rizzo","year":"1998","journal-title":"Mycotoxin Res"},{"key":"10.1016\/j.jpba.2025.116845_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.chroma.2020.461515","article-title":"Reduced graphene oxide-zinc oxide nanocomposite as dispersive solid-phase extraction sorbent for simultaneous enrichment and purification of multiple mycotoxins in Coptidis rhizoma (Huanglian) and analysis by liquid chromatography tandem mass spectrometry","volume":"1630","author":"Tanveer","year":"2020","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jpba.2025.116845_bib9","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.1016\/j.fct.2005.05.019","article-title":"Evaluation of a method to determine the natural occurrence of aflatoxins in commercial traditional herbal medicines from Malaysia and Indonesia","volume":"43","author":"Ali","year":"2005","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.jpba.2025.116845_bib10","doi-asserted-by":"crossref","first-page":"339","DOI":"10.5941\/MYCO.2014.42.4.339","article-title":"Incidence and level of aflatoxins contamination in medicinal plants in Korea","volume":"42","author":"Lee","year":"2014","journal-title":"Mycobiology"},{"key":"10.1016\/j.jpba.2025.116845_bib11","doi-asserted-by":"crossref","first-page":"3404","DOI":"10.1002\/jssc.202200420","article-title":"The presence and transfer characteristics of aflatoxins in medicinal herbs: From raw materials to edible dispensing granules","volume":"45","author":"Wang","year":"2022","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.jpba.2025.116845_bib12","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/j.foodcont.2017.08.032","article-title":"Detection of toxigenic mycobiota and mycotoxins in cereal feed market","volume":"84","author":"Hassan","year":"2018","journal-title":"Food Control"},{"key":"10.1016\/j.jpba.2025.116845_bib13","doi-asserted-by":"crossref","first-page":"2830","DOI":"10.1007\/s13197-021-05306-y","article-title":"Mycotoxins occurrence in medicinal herbs dietary supplements and exposure assessment","volume":"59","author":"Pallar\u00e9s","year":"2022","journal-title":"J. Food Sci. Technol."},{"key":"10.1016\/j.jpba.2025.116845_bib14","doi-asserted-by":"crossref","first-page":"125","DOI":"10.3390\/toxins13020125","article-title":"Occurrence of free and conjugated mycotoxins in aromatic and medicinal plants and dietary exposure assessment in the moroccan population","volume":"13","author":"Jai","year":"2021","journal-title":"Toxins"},{"key":"10.1016\/j.jpba.2025.116845_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodcont.2020.107621","article-title":"Assessment of aflatoxins and ochratoxin a in chili sauce samples and estimation of dietary intake","volume":"121","author":"Iqbal","year":"2021","journal-title":"Food Control"},{"key":"10.1016\/j.jpba.2025.116845_bib16","article-title":"Analysis of aflatoxins in traditional Chinese medicines: Classification of analytical method on the basis of matrix variations","volume":"6","author":"Zhao","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.jpba.2025.116845_bib17","doi-asserted-by":"crossref","first-page":"4160","DOI":"10.1002\/jsfa.7618","article-title":"Simultaneous determination of four aflatoxins and ochratoxin A in ginger after inoculation with fungi by ultra-fast liquid chromatography\u2013tandem mass spectrometry","volume":"96","author":"Yang","year":"2016","journal-title":"J. Sci. Food Agric."},{"key":"10.1016\/j.jpba.2025.116845_bib18","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.aca.2010.02.009","article-title":"An ultra-high-performance liquid chromatography-tandem mass spectrometry method for simultaneous determination of aflatoxins B1, B2, G1, G2, M1 and M2 in traditional Chinese medicines","volume":"664","author":"Han","year":"2010","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.jpba.2025.116845_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2022.108366","article-title":"A novel immunoaffinity column based metal\u2013organic framework deep eutectic solvents @ molecularly imprinted polymers as a sorbent for the solid phase extraction of aflatoxins AFB1, AFB2, AFG1 and AFG2 from cereals samples","volume":"187","author":"Kardani","year":"2023","journal-title":"Microchem. J."},{"key":"10.1016\/j.jpba.2025.116845_bib20","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.chroma.2018.03.015","article-title":"A monolithic column based on covalent cross-linked polymer gels for online extraction and analysis of trace aflatoxins in food sample","volume":"1548","author":"Wei","year":"2018","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jpba.2025.116845_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2024.110806","article-title":"MOF@N-doped carbon dots\u2013based dispersive solid phase extraction combined dispersive liquid-liquid microextraction of several aflatoxins from raw cow\u2019s milk samples prior to HPLC-FLD","volume":"202","author":"Khalilipour","year":"2024","journal-title":"Microchem. J."},{"key":"10.1016\/j.jpba.2025.116845_bib22","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1002\/jssc.201901129","article-title":"Combining ultrasound-assisted extraction and vortex-assisted liquid-liquid microextraction for the sensitive assessment of aflatoxins in aquaculture fish species","volume":"43","author":"Jayasinghe","year":"2020","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.jpba.2025.116845_bib23","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1080\/19440049.2023.2165172","article-title":"Modified-QuEChERS-LC\/MS method for the analysis of aflatoxins and ochratoxin A in coriander seeds","volume":"40","author":"Ouakhssase","year":"2023","journal-title":"Food Addit. Contam. Part A"},{"key":"10.1016\/j.jpba.2025.116845_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2022.135359","article-title":"Online solid-phase extraction based on size-controllable spherical covalent organic framework for efficient determination of polybrominated diphenyl ethers in foods","volume":"410","author":"Lu","year":"2023","journal-title":"Food Chem."},{"key":"10.1016\/j.jpba.2025.116845_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2022.107831","article-title":"Fabrication of a lignin-dopped monolithic adsorbent and its properties for the extraction of hyperin from Senecionis Scandentis Hebra","volume":"181","author":"Mao","year":"2022","journal-title":"Microchem. J."},{"key":"10.1016\/j.jpba.2025.116845_bib26","doi-asserted-by":"crossref","first-page":"6623","DOI":"10.1021\/jacs.9b01226","article-title":"Macro\/microporous covalent organic frameworks for efficient electrocatalysis","volume":"141","author":"Zhao","year":"2019","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.jpba.2025.116845_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2023.133017","article-title":"Fluorine-functionalized covalent organic framework as efficient solid phase extraction sorbent for adsorption of aflatoxins in nuts","volume":"464","author":"Wang","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.jpba.2025.116845_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2024.133755","article-title":"Integrating molecular imprinting into flexible covalent organic frameworks for selective recognition and efficient extraction of aflatoxins","volume":"467","author":"Su","year":"2024","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.jpba.2025.116845_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2022.134464","article-title":"Fast extraction of aflatoxins, ochratoxins and enniatins from maize with magnetic covalent organic framework prior to HPLC-MS\/MS detection","volume":"404","author":"Wei","year":"2023","journal-title":"Food Chem."},{"key":"10.1016\/j.jpba.2025.116845_bib30","article-title":"Size-controllable synthesis of large-size spherical 3D covalent organic frameworks as efficient on\u2013line solid-phase extraction sorbents coupled to HPLC","volume":"1284","author":"Chen","year":"2024","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.jpba.2025.116845_bib31","doi-asserted-by":"crossref","first-page":"3754","DOI":"10.1002\/chem.201704929","article-title":"A macroporous metalorganic framework with enhanced hydrophobicity for efficient oil adsorption","volume":"24","author":"Jing","year":"2018","journal-title":"Chem. -Eur. J."},{"key":"10.1016\/j.jpba.2025.116845_bib32","unstructured":"Validation of analytical procedures: text and methodology Q2(R1), in: Proceedings of the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use, Geneva, ICH, 2005. ICH Harmonised Tripartite Guideline, \u3008https:\/\/database.ich.org\/sites\/default\/files\/Q2%28R1%29%20Guideline.pdf\u3009."},{"key":"10.1016\/j.jpba.2025.116845_bib33","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.chroma.2014.08.037","article-title":"Optimization and validation of a quantitative liquid chromatography\u2013tandem mass spectrometric method covering 295 bacterial and fungal metabolites including all regulated mycotoxins in four model food matrices","volume":"1362","author":"Malachov\u00e1","year":"2014","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.jpba.2025.116845_bib34","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.foodcont.2016.08.040","article-title":"Effect of different microbial concentrations on binding of aflatoxin M1 and stability testing","volume":"73","author":"Ismail","year":"2017","journal-title":"Food Control"},{"key":"10.1016\/j.jpba.2025.116845_bib35","first-page":"462","article-title":"Extraction of sulfathiazole from urine samples using biosynthesized magnetic nanoparticles, Iran","volume":"16","author":"Maham","year":"2017","journal-title":"J. Pharm. Res."}],"container-title":["Journal of Pharmaceutical and Biomedical Analysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0731708525001864?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0731708525001864?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T02:14:13Z","timestamp":1762308853000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0731708525001864"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":35,"alternative-id":["S0731708525001864"],"URL":"https:\/\/doi.org\/10.1016\/j.jpba.2025.116845","relation":{},"ISSN":["0731-7085"],"issn-type":[{"value":"0731-7085","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Macroporous covalent organic framework for efficient online solid-phase extraction of aflatoxins from traditional Chinese medicines","name":"articletitle","label":"Article Title"},{"value":"Journal of Pharmaceutical and Biomedical Analysis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jpba.2025.116845","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"116845"}}